Why does methylfolate act as the off-switch for the glycine buffer system?

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  • Опубліковано 1 січ 2025

КОМЕНТАРІ • 16

  • @Phi1eap
    @Phi1eap 3 роки тому +6

    Please do piece containing lists of popular supplements that shouldn't be taken before bed because they stop autophagy, and list that are ok to take in fasting state/before bed, especially of those that help to fall asleep. I think Scutellaria is ok before sleep, but they often add fillers from rice powder, are amout of carbs used as fillers are significant?

  • @notsogreen
    @notsogreen 3 роки тому +6

    It's complicated....

  • @richardreeves6708
    @richardreeves6708 3 роки тому +12

    could you repeat that

  • @MarmaladeINFP
    @MarmaladeINFP 3 роки тому +4

    What happens when supplementing SAMe. My bottle says to take SAMe 3-4 times a day. But if it indicates a fed state, what does it do to the body to keep the body in a fed state? I also usually limit my meals to the morning. So, should I limit my SAMe supplementation to the morning as well?

  • @fyrerayne8882
    @fyrerayne8882 Рік тому +2

    So the ideal time to take a methylfolate supplement would be right before a meal that contains a high amount of methionine?

    • @chrismasterjohn
      @chrismasterjohn  Рік тому +4

      The normal time to get folate is at a meal. And under normal conditions the methyl group doesn’t matter, because your cells will add methyl groups to the same molecule 18,000 times a day when they find it appropriate, which is when methionine intakes have dropped.

  • @BlackSeedOil20
    @BlackSeedOil20 23 дні тому

    Can someone who eat enough proteins and thus making methionine be low in cysteine?

  • @rocpile2773
    @rocpile2773 8 місяців тому

    Does this mean that low SAM-E from folate deficiency can inhibit transsulfuration?

  • @futureflow8645
    @futureflow8645 3 роки тому +2

    Any helpful advice on why the immune system attacks ragweed & other pollens?
    What makes the immune system fight against some allergens having hay fever etc, instead of fighting EBV & other stuff.
    Are these things related to some deficiency?

    • @Phi1eap
      @Phi1eap 3 роки тому +1

      You can unsesitize to grass pollens, consult allergologist. Allergy is something like fucked up vaccination, for example if you have infection, and eat something that is known allergen (it shares some mimicry/similarity in molecule shapes to molecules that are also present in pathogens) during that infection, body can mistakenly train immune system to react to substance contained in that food. That is called cross reaction. Way to fix it is increase Treg cells taht increase tolerance and expose yourself in that state to low dose of allergens for prolonged time. Other way is to use probiotics to correct dysbiosis, which is best done with multiple sampling of flora. Some autoimmunities are just undiagnosed hidden infections, whith those, Moringa, Qercetine and Andrographis may help, those are wide spectrum antiinflammatiories, antyvirals, antibacterials.

    • @eugeniebreida
      @eugeniebreida 3 роки тому

      @@Phi1eap Watch out on Moringa, or very high energy/ Insomnia will kick your behind.
      Quercetin 3x’s day good.
      I should try the androgrphis,(yt blocking your comment while i’m texting - sorry attempt to remember spelling)

  • @Phi1eap
    @Phi1eap 3 роки тому

    So you shouldn't take methyfolate if you don't have MTHFR mutations because it screws up fed/fast state signaling?

  • @vrillion7588
    @vrillion7588 5 місяців тому

    I think Comment guy taking About Methyfolate supplement ?

  • @shackinternational
    @shackinternational 3 роки тому +1

    Che supercazzola!