Serotonin The Multifunctional Neurotransmitter: What it Is and What it Does
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- Опубліковано 2 січ 2019
- Dr. Dawn-Elise Snipes is a Licensed Professional Counselor and Qualified Clinical Supervisor. She received her PhD in Mental Health Counseling from the University of Florida in 2002. In addition to being a practicing clinician, she has provided training to counselors, social workers, nurses and case managers internationally since 2006 through AllCEUs.com Learn about the many functions of serotonin including anxiety relief and depression recovery and how to improve it naturally with Dr. Dawn Elise Snipes. #serotonin #depression #neurotransmitters
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Thank you for new learning and sharing your knowledge on us will very appreciated.
Welcome
This was SO Great! Thank you for all of your tid bits also : ]
You're so welcome!
So happy I found channel.
Wishing you peace, health and happiness
Thank you so much.
very nice explanation thank you so much
You are most welcome
Thank you so much, very interesting
You are very welcome. Thanks for watching.
Excellent review Dr. Dawn!
Thank you kindly!
Great info, thank you
Glad it was helpful!
Thank you so much for this lesson, I just got my degree in Biochem and I was astonished the endocannabinoidal system was not mentioned once! I love this professor!
TY!
5:05
Thats a very new area of research,it wasnt even mentioned when I trained in medicine 20 yrs ago.
Dopamine is considered to be prolactin inhibiting hormone. Dopamine agonists such as Parlodel (bromocriptine) are used to manage hyperprolactinemia and menstrual irregularities due to elevated prolactin level. On the other hand, dopamine antagonists such as domperidone (Motilium) are used to increase milk production after delivery.
wait , isnt that the opposite of what she said? low dopamine ---> low prolactin?
There is a negative feedback look. You're right in that DA decreases prolactin production
I think she mis-spoke with the dopamine. High dopamine causes low prolactin
Prolactin and dopamine have an inverse relationship😢
We used intravenous dopamine to increase blood pressure & perfusion to the kidneys in the intensive care unit. Dopamine is incredible for the body.
Amazing content - thanks for sharing!!! ❤
Thanks for watching.
Very thorough. Your video on se may be the best on youtube. Ty ty
Wow, thank you!
So very helpful. Thank you.
So welcome!
amazing thank you!
You're very welcome!
Doc Snipes, I just love your videos!
And I am grateful to be of help and love the fact that you are watching them. What did you find most useful from this video?
Thank You Sincerely!
This was very informative and interesting thank you!
You’re so welcome. Thank you so much for watching
Amazing video. Thank you so much! Abraços do Brasil!
Glad you enjoyed it! Are the Spanish subtitles any good? I don't speak Spanish, so I have no idea how good the translations are?
They speak portuguese in Brazil.
Absolutely in incredible. It would be nice if you had a flash card system that people could use. One side symptoms the other side Neurotransmitter infomatiom. I love you for the work you do. May the great Father/ Mother creator bless you.
absolutely mind blowing
Thanks for watching. Wishing you peace, health, and happiness.
Thank you thank You 🙏🏽
I’m crying bc u just helped me understand what is wrong with me
All these diagnoses and it’s causes from serotonin issues
Wishing you peace, health and happiness
@@DocSnipes THANK YOU LOVE!
I HAVE LEARNED A LOT TOO!!😉😁🤍
I always thought it was a given that dopamine deficiency was the leading cause of depression. The problem is modulating dopamine is difficult and dangerous in some cases.
Best cure would be to recreate society entirely because there are too many direct causes of depression in our everyday lives.
Thank you so much for watching and for sharing your opinion. What is your favorite tip from the video?
Serotonin is the happy hormone 😊 that makes you feel happier
@@cindyrobertson3780 That's simply not how it works. There's much more nuance involved in levels of neuromodulators, and too much serotonin can actually cause depression in and of itself.
Similarly, dopamine isn't just the "motivation neurotransmitter".
@@BasedChadman I know.
I've been taking an ssri for 20 years and found out recently I have a heart murmur. Interesting. Thanks so much.
Thanks for watching.
The SSRI I am on helps to keep my heart murmur in check. My mom, her twin, and her daughter all have a murmur and are on low dose SSRI for heart rate management.
I would like to hear her take on downregulation of 5HT1A/2A after prolonged use of reuptake inhibitors. Particularly 5HT1A inhibits serotonergic activity. I want to know more about its neuronal plasticity effects as patients take these meds for years. It's also important to note that immediate inhibition of SERTs does not mean immediate clinical effect as antidepressants take weeks.
Additionally, there are studies out there indicating NEs prevalence in conjunction with 5HT, so SNRI may be a more viable choice.
You are right, alteration of serotonin impacts NE and dopamine levels as well. I do discuss SNRIs in the presentation on norepinephrine and SNDRIs in the presentation on dopamine.
Suggestion that a key part of the need for sleep is the body's need to make serotonin, which it does in a symbiotic relationship with gut bacteria in the large intestine.
We sleep to first produce serotonin, then to draw it into the body through the extraction of water in the large intestine.
Though it can be synthesized, there seems to be a major difference in the health benefits from the micro made serotonin, and the artificially made serotonin.
Here's some notes on both how important serotonin is and how widespread it is in all living things.
Besides mammals, serotonin is found in all bilateral animals including worms and insects,[19] as well as in fungi and in plants.[20] Serotonin's presence in insect venoms and plant spines serves to cause pain, which is a side-effect of serotonin injection.[21][22] Serotonin is produced by pathogenic amoebae, and its effect in the human gut is diarrhea.[23] Its widespread presence in many seeds and fruits may serve to stimulate the digestive tract into expelling the seeds.[24]
Gut bacteria manufacture about 95 percent of the body's supply of serotonin, which influences both mood and GI activity.
Thanks for watching!
Thanks for the very useful lecture. You mention low dopamine means low prolactin around 5 minutes through the presentation. I thought that dopamine acts as an inhibitory factor for prolactin secretagogues in the anterior pituitary. Again prolactin antagonists are used in some cases of hyperprolactinaemia. Is it in a different context where this relationship is different?
At that point in the video right now and thinking the exact same thing. Now I wonder how accurate the rest of this video is??
V ery nice information. Daily breath observing meditation for 10-20 minutes increases serotonin and relaxes the mind.
Thanks for sharing
I have been doing the exact opposite of all the points you mentioned to increase Serotonin for past 2 yrs
No doubt I have bad mental health with Excess Dopamine activities taking up all my day. But I never reach that state of happiness or in other words no serotonin abundance.
Any follow-up to report? Did you try any of the practices she suggested? I hope you’re doing better.
@@ngprovidence1275 yes
Any update?
I take Zoloft for my anxiety.
Take lsd or Mushrooms
Well, I know what my problem is and that is Addison’s disease and it’s screwing up my life and I am trying to do the best. I can to balance myself out because I don’t take medication and sometimes it affects my sleep well of course it affects everything I really enjoy your videos and looking for all the help I can get.
If higher levels of serotonin are found in more anxious people, then why are SSRI's and SNRI's so commonly prescribed for anxiety disorders? Genuinely curious here if someone has an answer. Effexor has helped immensely with my anxiety and panic attacks.
Hmmmm.. i remember that response to hormone increasing will be receptor lessening. Maybe in this model...
Sorry for bad english
Depends on the receptor subtype activated by serotonin.The serotonin hypothesis of depression is also incorrect.
Fantastic coverage. Thank you. Would be nice to know how ashwagandha impacts serotonin / receptors
Thanks for watching!
I didn’t help me
Rhodiola rosea, was more effective for me, over aswaghanda.
39:00 You missed that 5-HT2B controls the general release of serotonin through its transporter, which in turn will influence all the serotonergic system. You upregulate this receptor a bit and you get a significant increase of serotonin in all receptors.
24 mins good about serotonin
Watching this whilst having lunch at work hehe. Thank you
Welcome.
26:43 "5-HT1A agonists decrease learning... I don't know why"
Because 1A activation decreases glutamate (and acetylcholine in part) so you get less LTP.
Is there any link between DHEASO4 and Serotonin ..? Tell
I am going through benzo withdrawals. Not been able to sleep for the last three months. I don't know if serotonin could help
Hey doctor,
great video. How about Modafinil 400 mg per day combined with Escitalopram 10 mg per day? My doctor and my online medication checker sais that it's fine, but in the video it doesn't sound like it's fine...
You need to consult your medical doctor, or get a second opinion from another medical doctor if you have questions.
Thanks for watching. Wishing you peace, health, and happiness.
@@DocSnipes alright, thanks for your answer. I will do that
Sir in how many months sero and dopa balances
There are too many individual variables to quantify that blindly. Age, reason for imbalance, duration and severity of the imbalance, genetics, nutrition, current stress level, sleep quality, confounding physical conditions, gonadal hormone imbalances etc.
Hi Mam, I am Shanmukha from India, may I ask you a question.
I am taking ssrs(seretonin, nextio 5) as prescribed by doctor with Lonozep0.5.
Now I am tampering it by nexito 2.5 and lonizeo 0.25.
When I stop a day taking these dose, my head is slightly spining and getting stability issues, is this normal and will go away slowly? Can I stop taking these?
My age is 31 and weight is 68, height 5' 5.
As you mentioned in video I am doing sun bath 10 min a day, exercise to naturally increase serotinin. Please kindly advise...
You should consult your Medical Doctor.
Super
I have Serotonin Syndrome. My doctor had me on 3 Serotonin meds for 3 years- cyclobenzaprine, Effexor and Trazodone. I've been too ill to function for 2 years and no doctor was able to diagnose what was wrong. I recently researched the meds I was on and discovered that the overload of Serotonin in my system was what was making me so sick. I'm off them all now. Would you know how long before it leaves my system and how long before I'm well again? Thank you so much if you could let me know.
The meds are typically out in 30 days, but physiological alterations can take a lot longer and dependent on the individual.
@@DocSnipes Thank you.
@@DocSnipes I went to hospital yesterday because I'm hugely bloated and the amount of urine and feces coming out are very small. I also have no bladder or bowel control. Can you recommend something I could take for this? Oh, and genius doctor told me there's no such illness as Serotonin Syndrome.....
@@lisaboyle8138 moderate you diet!!
Ginger and lemon in the morning !
Drink more greens blend with water and ice like pineapple cucumber green apple celery one blended
Add a big chunk of aloe vera lemon juice just to break the aloe vera and cut meat and cheese
Also check your hormones!
And exercise!
I recently wind off myself from my ssri and is a huge difference!!
Amazing how I am recuperating my life back again!!!
No more anxiety or panic attacks!!
It all started to get worse when I was put on this devilish medication
Thank God I opened my eyes and I am free again!!
Good luck to you!
Hii, what kind of symptoms you have ??
Hi mam how are you I hope you are good mam I am patient of OCD doctor prescribed me prozac 20mg and clomipronine 75mg I take this medicine from six months mam what you prescribed me
Increase Serotonin 49:40
Thank you sir
Have you ever heard of the Runner's High
Is there a way to contact her for a medical mystery for which I sense she may be able to provide insight?
members.docsnipes.com/ Have a good day.
@@DocSnipes Thank you. Looking into it now.
And yet 5 htp and SSRIs mess with my sleep and either cause insomnia or restless sleep. What gives?
10:00 Couldn´t it be that that excess serotonin is the one produced/learned to be produced during acute anxiety periods? In an acute anxiety period any evitative (disfunctional) behavior is reinforced. When the acute anxiety is over, the learning and the behaviour stays there and keeps producing anxiety, generating a viciuos cicle between learned helplessness and reward.
She is so pretty
Thank you for your kind words and thank you for watching the video
What's the reason low dopamine correlates with low prolactin? I thought dopamine inhibits prolactin?
Here’s an awesome video on the connection between prolactin and dopamine
pubmed.ncbi.nlm.nih.gov/18477617/
It is true that Ionized air helps increased Serotonin ?
It decreases it I think
Negative ions found in nature have been found to increase seretonin, positive ions produced by electrical devices decrease seretonin.
I believe I’m exhausted because I’m tired a lot because of my adrenals and I stay away from coffee even though I would love to have a cup I don’t because it’s not helping my adrenals at all and I do my best
Thanks for watching the video and for sharing
How about taking magic mushrooms and serotonin receptors
Hello Remeron
I think it sounds more gooder When you say psychotropics that have psychedelic effects fax because the word psychedelic has been misused and misrepresented for a long time. They got the cart in front of the horse so to speak
Thank you for watching the video
Hey. U told wrong. Dopamine is opposite to prolactin Plz correct ur concept mam
Dopamine inhibits prolactin; serotonin may inhibit dopamine production. Both are mood regulators
Dopamine agonists "decrease" dopamin. You mention that low dopamine, low prolactine. So dopamin agonist causes prolactine increase. I think it is not true. Dopamine agonists like bromocriptine is used to treat hyperprolactinemia
Thanks for watching. Dopamine agonists activates dopamine receptors. Dopamine antagonists are dopamine receptor blockers.
What I get out of this is to not take anything.
Exactly!!!
Just learned that taking ssri's causes valve damage in the heart
Which is why I am now very sure I won't take my stupid antidepressant
Pristique 50mg any more !!
I have enough since 2011
Not any longer!!!
I am done with pharma since 2 week ago and never will!!
@@yardartistry4121 good ! That stuff is so bad for you !!!! Diet and herbs are the way ! Exercise and yes sun !! All natural is the only way !!
All natural has not been working for me :/
I exercise and eat lots of green things.. go outside, etc.
@@forgor4410 hmm ... have you ever tried magnesium ? I take magnesium glycinate by the brand nested and it’s been really helping me .
All I know is Zoloft lowest dose helps me but they are saying it can cause Alzheimer’s so what to do?????
Im on 10mg citalopram of i get 5mg higher im so sick my heart is beating out my chest heavy breating in my past i taken 20mg for years but now my body can not handle it i think🤢
I am sorry to read that. Please talk to your doctor about your symptoms. Large citalopram ingestions can lead to serotonin syndrome and severe serotonin syndrome can cause death, if not treated.
Marcy's and I have to work around my grocery stores
For many years I've tried to find out a basic reason why we and almost all creatures need to sleep.
So taking a break from physics ...
Suggestion that a key part of the need for sleep is the body's need to make serotonin, which it does in a symbiotic relationship with gut bacteria in the large intestine.
Suggestion that we sleep to first produce serotonin, then to draw it into the body through the extraction of water in the large intestine.
Though it can be synthesized, there seems to be a major difference in the health benefits from the microbiome made serotonin, and the artificially made serotonin.
Here's some notes on both how important serotonin is and how widespread it is in all living things.
Besides mammals, serotonin is found in all bilateral animals including worms and insects,[19] as well as in fungi and in plants.[20] Serotonin's presence in insect venoms and plant spines serves to cause pain, which is a side-effect of serotonin injection.[21][22] Serotonin is produced by pathogenic amoebae, and its effect in the human gut is diarrhea.[23] Its widespread presence in many seeds and fruits may serve to stimulate the digestive tract into expelling the seeds.[24]
Gut bacteria manufacture about 95 percent of the body's supply of serotonin, which influences both mood and GI activity.
Serotonin was shown to exert functions in innate as well as adaptive immunity. Serotonin stimulates monocytes (23) and lymphocytes (24) and hence influences the secretion of cytokines. Vascular smooth muscle cells respond to serotonin by synthesizing interleukin (IL)-6, a possibly atherogenic mechanism (25)
Serotonin is a neurotransmitter than has been identified across all forms of life. In recent years the presence and function of serotonin in plants (phytoserotonin) is becoming an increasingly active area of research. Serotonin has been found to function as a plant growth regulator, and a stress defense molecule.May 24, 2017
Although serotonin (5-hydroxytryptamine, 5-HT) was discovered 60 years ago (1), the study of serotonin and its receptors continues to yield new biological insights of medical relevance in virtually all major organ systems, including the cardiovascular, pulmonary, gastrointestinal (GI), and genitourinary systems as well as the central nervous system (CNS) (2).
Serotonin is made from the essential amino acid tryptophan. An essential amino acid means it can’t be made by your body. It has to be obtained from the foods you eat.
Why prescribe SSRIs for anxiety. If they increase serotonin = more anxiety.
Damn i was just searching for a song
Anyways good video, keep up the good work
Thanks for watching. Wishing you peace, health, and happiness.
THANKS FOR THE GREAT PRESENTATION. I KNOW IT IS NECESSARY FOR THE UNDERSTANDING OF MANY THINGS BUT THE MORE I THINK ABOUT IT THE MORE IT SEEMS CLEAR TO ME THAT THE MENTAL HEALTH SECTOR IS ENTIRELY TOO MUCH SO BASED ON UNIFORMITARIANISM WITH NATURALISM. MECHANICALLY FIXING PROBLEMS THAT QUITE RIGHTLY OUGHT TO BE CONTROLLED BY PROPER THOUGHT.
Glad it was helpful. Thanks for watching.
Very nice. Seems like throwing spaghetti at the wall to see what sticks, in psychiatry.
Thanks for watching.
You don't need drugs,
Good diet and activity fix this problem.
High animal base fat carnivore diet, zero carb.
5 years on this, never felt better.
I am so glad that diet worked out for you. Congratulations! Thank you for watching the video! What was your favorite tip from it?
@@DocSnipes The most important thing that I learned from the video is that, messing with any hormone can affect other hormones, and it is very dangerous to use these drugs.
Doctors never try to find out the root of the problem, they never ask what is your diet like? Saturated fats are demonized by big pharma, which are very important for brain health. Eating carbs and processed foods, cause depression, addiction, diabetics.....etc... High saturated animal base diets are demonized, by big pharma.
Why do people who are having a good diet ie eat plenty tryptophane, sill get low serotonin
There are several reasons why someone might still have low serotonin levels despite consuming a diet rich in tryptophan, the amino acid precursor to serotonin. Here are some factors that could contribute to this issue:
Nutrient Absorption and Conversion: The body requires various vitamins and minerals to convert tryptophan into serotonin, such as iron, magnesium, calcium, vitamin B6, and folic acid. If there is a deficiency in any of these nutrients, the conversion process may be impaired.
Vitamin D: Vitamin D is involved in the serotonin system, and insufficient levels of vitamin D can affect serotonin production.
Digestive Health: The gut microbiome plays a role in breaking down tryptophan. An imbalance in gut bacteria or poor gut health can hinder this process.
Genetic Factors: Individual genetic differences can affect how efficiently tryptophan is converted to serotonin.
Hormonal Influences: Hormones such as estrogen and testosterone can potentiate the effects of serotonin. Low levels of these hormones might contribute to lower serotonin activity.
High Cortisol Levels: Stress and high cortisol levels can suppress serotonin production.
Dietary Composition: The presence of other amino acids in the diet can affect the absorption of tryptophan. Consuming tryptophan with a high carbohydrate meal can increase its absorption into the brain.
Medication Interactions: Certain medications can affect serotonin levels, and dietary tryptophan variations can influence the effectiveness of SSRIs in major depression.
Overall Diet Quality: Even if the diet is rich in tryptophan, other aspects of the diet may be lacking, which can affect overall health and the body's ability to produce serotonin.
It's important to consider these factors as part of a comprehensive approach to understanding and potentially addressing low serotonin levels. If someone is concerned about their serotonin levels, it would be advisable to consult with a healthcare professional who can assess their individual situation and provide personalized recommendations.
@@DocSnipes Thank you for such a prompt and detailed response. In Hindsight, I should have realized that some of factors were already explained in your slide show. I must be deficient in one of those 5HTP somewhere, which has hindered my learning abilities! I look forward to more of your knowledge that you are sharing.
29:55
low dopamine ---> low prolactin? maybe prolactin should be high?
Off topic, putting salt in coffee takes away its bitter taste.
Thanks for the tip.
I appreciated this comment 😄
Nice contradiction yup
Thanks for watching.
WHEN IT COMES TO SEROTONIN, YOU'RE TALKING ABOUT PSILOCYBIN.
LET ME TRANSLATE THAT FOR YOU. WHEN YOU'RE TALKING ABOUT SOUL WE'RE TALKING ABOUT MUSHROOMS.
SEROTONIN IS THE SOUL. THE SEROTONIN SYSTEM IS THE INDIVIDUAL SOUL. SEROTONIN IS THE SUBSTANCE CALLED SOUL.
YOU KNOW THE OLD SAYING...
CHICKEN SOUP IS GOOD FOR THE 5-HT.
LOOK AT IT THIS WAY. HOW MUCH SOUL DOES IT TAKE FOR A CHICKEN TO RUN AROUND WITH ITS HEAD CUT OFF?
ALL LIVING CREATURES HAVE SEROTONIN. SOUL.
THE LIMBIC SYSTEM IS THE EGO WITH ITS LAST RESORT DEFENSE THE ID.