RESET Your Age, LOOK Younger and Live FOREVER (Seriously!) | David Sinclair
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- Опубліковано 11 чер 2024
- This episode is sponsored by Future. Future makes one on one training available to our audience for just $19 Go to tryfuture.co/impact to sign up to crush your fitness goals!
Are we closer to becoming biologically immortal? What would you strive to do or dream of if you could extend your life to even 150 years? Until recently the idea of longevity felt more like reaching your 90s and possibly 100 at best, and if you manage to accomplish that goal, a high quality of life would be best and expected. But what if you could extend your lifespan by even 10 years? Making sure that those years are exciting and meaningful would be a priority. Dr.David Sinclair, a world-renowned geneticist, is joining Tom in this episode to break down exactly why it is that we age on a cellular level, and what is now becoming possible in terms of slowing down our biological clock and even possibly reversing our biological age. If you want to know what you can do to start improving the quality of your aging life and stay younger longer this episode is for you, and you’ll want to check out Dr. David Sinclair’s newest podcast, Lifespan (link below).
SHOW NOTES:
0:00 | Introduction to David Sinclair
0:28 | Why We Age
9:40 | What Goes Wrong With Aging
23:44 | How to Reverse Aging
37:35 | Face Adversity
45:37 | How Metformin Works
55:02 | Lifestyle for Longevity
“We could have reversed aging just by making all cells a stem cell, we have the technology to do that.” [23:43]
“So we're reversing the aging of the eye, that's not hard at all, but we can reverse the age of the liver, the skin, other labs are doing the spleen, thymus, through this method.” [31:13]
“Humanity lucked out that we can actually do this and that there's a backup copy of youth in each of our cells that can be tapped into.” [32:03]
“We don't think about what it's like at the end, it is not fun. It's not typically like, Oh, you just go to sleep. Those are the lucky ones.” [36:39]
“The main concept that I think we all need to remember is that our bodies respond well to perceived adversity.” [38:55]
Follow David Sinclair:
Website: sinclair.hms.harvard.edu/
UA-cam: / davidsinclairpodcast
Podcast: anchor.fm/lifespan
Instagram: / davidsinclairphd
Twitter: / davidasinclair
Facebook: / davidsinclairphd
Do you think humanity will achieve immortality in your lifetime?
Hopefully it doesn't. It could very well lead to a tyranny of posthumans over humans. Also, the thing that makes life so precious is the fact that it's finite. Remove the urgency and watch modern life become even more devoid of meaning.
Faith and Reason are symbiotic and complementary. Brother, you have everything one could want except the one thing that matters most.
We are already immortal as consciousness. But the body is subject to the universal laws of decay. Your body will die along with your ego self. Your body is just food that you ate, it’s not you. You are not your thoughts either, those are also just things you have gathered from outside. Who are you? You are definitely confused about what you are, but do you even know who you are?
I sure hope not.
We’re already immortal! Our real life begins in the Hereafter, this life is but a short exam. A “simulation” if you want to call it that. Nothing wrong with trying to extend this life if the intention is to serve God more, but death is inevitable and required for our souls to transition from this world to the next.
The key to looking younger is telling people you’re older.
jijijijiji
@@freedom4dworld642 ❤❤❤
😂 I like that!
David really looks great for 52
@@Sunshine-co8vf 😄
I've reversed aging by no longer spending time with my mother in law
🤣
😂
Lol
🤣🤣😵
Try pirn for a week and week and see what happens
I am legally blind in one eye and have very low vision in the other. So as I heard the part about blindness being reversed I immediately started to cry because it gave me so much hope. Thankank you so much. God bless you and your family stay safe everyone. 🙏🕊️👸🌹
❤
Bless you, don’t follow these crooks sending you watsap numbers ok. Stay safe, keep the faith.
@@mattcunliffe2807 report them.
Technology is the closest thing to magic we have in the real world. Attribute it to Arthur C Clarke if you like but I thought this myself as a kid when I was pre 10, just looking at the world I have been born into. Technology and science can do amazing things
Search "dr berge eyes" he has explained why it happened and how to heal/ improve eye sight, how to stop damaging it
At 43 years young I’m very healthy and grateful. I believe that HOW you feel is very important on how you age. But I’ve always had this undeniable belief that I’ll live to 120; with today’s knowledge I truly believe I will.
Hey dude, I think you could be more optimistic, especially after watching this video.
I reversed my age by selling my house, out of debt.
STRESS KILLS.
Very wise decision
@@hermanhelmich thank you!
I am gonna do the same.
@@magdal3nam.353 FREE YOURSELF! While folks are refinancing, many are selling homes. Be free!
N move to asia, thailand vietnam, indonesia, malaysia,..❤
This year has been ground breaking for me. I have applied many of the suggestions that I have gotten from this channel and Dr. Berg and this year for the first time since I was 13 I am not overweight. My goal now is a simple one and I feel like it will heighten my health benefits to the max and that is to maximize my digestion. With proper digestion not only will I look great but feel great too! Happy Health people!!!
Check out sten ekberg too he's got great videos too
well, maybe youre not overweight anymore rather cause you got cancer and it essentially consumes you. okay, sorry, thats not funny. but imagining that youd panic right away is kinda hilarious.
@@muzzletov is it?
Listen to the podcast of David Sinclair and pay attention to the companies that are supporting him. If you are serious about living well. It still might cost you $$. But you would invest in your health than paying the medicine to make you well or trying to be healthy.
@@muzzletov huh ???
I'm sitting here working from home feeling EXACTLY the way he described at the end. Ate lunch had too many bbq chips, iced coffee w/ whip cream for breakfast... wondering why around 3 I need a nap, thinking I didn't sleep enough. I'm seriously gonna try Intermittent fasting and cutting down on sugar because this is ridiculous. Also, his work is amazing. Future generations will thank him!
Good luck Bri, if you really embrace fasted focus lifestyle and keto/carnivore diet you'll lost the weight and feel amazing. That's what it did for me on this journey the last six years of my life and I am a new man with much more energy!!
I can completely relate
You have no idea how nice your future's gonna be if you just man the hell up and stay off sugar Better
When I was eating less I had the most enegy and my sht was a lot less messy and healthier lol
💯
How to stop aging: be black or asian
Our body is ‘always making energy otherwise we would be dead in less than 30 seconds’ was one of the most profound real things he said that has me understanding why we meditate and focus on our good thoughts everyday. Making energy work for us is our goal daily
Tom,
I’ve followed you for years now and I have to say- while I didn’t think it was possible, your interview style has gotten even better!
I love the questions you ask. I love the level of preparation you got through for each guest. I love the genuine interest you have for the information your guests are there to share.
I’ve listened to Dr. Sinclair dozens of times and have loved every single one. You’ve found a way to get even more out of him. The excitement he exudes as he’s answering your questions has me thrilled to hear the next words he’s going to share.
Thank you both!! 🙏
I think this has become one of the prime podcasts in existence today. Tom, you are doing a great work by bringing together all these great minds and allowing their ideas to be public. Whatever happens, whether we live forever or not, you have done a wonderful thing in your life. And there's no limit to where you can go with it even in the "natural" lifespan.
So, sincerely thank you for all you're doing.
If you just stare into David's gaze, you'll feel 10 years younger
Lol
can i just say - everytime that Tom interupts - i wanna get aggravated - but then he somehow makes me appreciative of the questions he asks and the way he frames his current understanding …. and then always makes sure that the topic goes back to when he interrupted. that is literally GOAT :) this one of the best interviews i’ve ever seen
You’re more generous than I. I watch the guests and I swear I can see their eyes glazing over, wondering when he’s going to let them talk about what they were invited for. But he’s harmless.
Thank you, Tom! This episode was top class!
Adverse Childhood Experiences (ACEs) show that the more (unhealed) trauma, the shorter your life expectancy. Emotion is the most powerful aspect of health.
Our hearts are literally radio transmitters, and the signal is modulated by our emotional state. That signal impacts the genetic expression of every strand of DNA in your body.
How much trauma you are carrying can be easily revealed by measuring your Heart Rate Variability (HRV). As you age, your HRV reduces...unless you heal your wounds...especially the wounds that most everyone views as normal. Most of the emotional trauma you experienced happened before you were even conscious of yourself as an individual (conception through about 18 months of age).
Heal those early wounds, and you will easily live for hundreds of years. Heal all of your wounds and you will have an indefinite lifespan...no nutritional supplements required.
Unresolved trauma is something that these biohackers never look into. They only want to add numbers to the overall lifespan instead of improving the overall quality of that lifespan. The more I've faced and healed my past trauma the more I feel alive.
So true. I’m 27 and I’ve got unhealed trauma. My connection to my body is minimal and my posture is bad. I’m trying to heal it through spiritual work, which I found out recently is the right way. Mind and body are definitely linked together.
We specialize for reason. Everyone can’t do EVERYTHING. If the people you call biohackers don’t focus on trauma… well then YOU can do that and educate the rest of us with your findings .
Also, I don’t understand why everything has to be “either or” we can literally apply both approaches and live healthier lives since both approaches are important 🤷🏾♂️
@@Remag123 I also believe in using both, but I see the “nutraceuticals” as training wheels that we will eventually discard because our highly efficient metabolisms will be able to provide the energy for our bodies to manufacture everything needed for perfect health…for as long as you want to stay on this rock! 😁
I'm reversing my age.
Wherever I go, I always walk backwards
My girlfriend says I'm acting like an eighteen year old.
Itvs working already!
what lol
Dr. David Sinclair is amazing. Thank you for inviting him again.
A great beautiful healthy day to you Tom, Thanks a million, I think I watch this episode at least 5 or 6 times, very informative, thanks for asking great questions, and opening the puzzle more and more for me, awesome interview with Dr. Sinclair, thanks again, keep it up.
Sinclair is so amazing. True science based doctor who explains things so well.
Sinclair is obviously in love with his work, refreshing and a pleasure to watch.
This is absolutely amazing Sinclair and Tom. This interview is mind blowing. Thanks for sharing knowledge and your expertise to help everyone who listened to your program. Thanks again GB
It´s so hopeful for me to realize we can focus our energy and pocket on the celullar repair and hopefully reverse our age instead of wasting time and money on supplements that will have not that much effect on a long term for us. The podcast David has is incredible. I like his ability to explain things in a very clear way.
Wow! I didn't know. Vitamin C doesn't
work, except it would of saved the 100,000 British sailors that died of
Scurvy. They've found it works on
Cancer. See the million dollar study
in Australia. It works on Heart disease
& Strokes according to Doctor Matthias Rath. It can knock out a Cold if you take
it quick enough. Poor old Linus Pauling
taking 18 grams a day & living into his
90's. Who wants health and a long life?
Don't run out to get some. Promise not
to tell. It's a secret. 😆
I'm about to watch this and I'm very excited as this guy is one of the top in his field, but I do hope you don't keep interrupting him as he is incredibly knowledgeable.Sometimes bro you don't let your expert guests finish their thought or you steer them in another direction just as it's getting to the juicy parts.
Fingers cross you don't kill his flow with constant interruptions, sorry bro just keeping it real!
Tom, you changed my life for the better! Thank you :)
This interview is freaking wonderful! It'll help tons of people! Thank you Tom and thank you David for your service to the world!👏🏼👏🏼👏🏼
Damn it’s fascinating on one hand and really fucked up on the other hand what humans do to animals in labs. How cold and calm he was able to say “we gave the mouse glaucoma” it’s just a normal part of his day, damn.
remind me of all the aliens abduction story of what alien do to us while they abducting us for experiments lol
I wonder if this man has any emotions..??
This conversation is so fascinating. Thank you.
Every being on earth is only here temporarily. Enjoy the time we have.
Phenomenal!
Ps. I wish the audio volume was just a bit higher.
Death is definitely inevitable- I don’t care how far advanced we become. We will all face it & should be thinking about where we’ll spend eternity. However, we can reverse the signs of aging - this is actually attainable
Amen 🙏🏿 🙏🏿 finally someone said the most important message, which is the power of the gospel, Jesus save, he die so that you and I will live, he who have Jesus Christ, shall not die, but have eternal life, we have a choice to choose were we will spend eternity, I urge you, to choose life eternal, Jesus in John ch11v25 "I am the resurrection and the life, he that believeth in me, though he were dead, yet shall he live". Salvation is free come to know Jesus today, and you shall have eternal life, God bless you in Jesus mighty name 🙏🏿 🙏🏿 ❤😘.
Yup , having wisdom is all we need
Yep, even if we can stop the aging process, we can still be killed by violence, war, disease, natural disasters, etc. Some people might be lucky to live hundreds or even thousands of years, but eventually, they will be killed in some way.
@@bigguy130 reason I don't care much about the flesh dying compared to spiritual death (eternal death)
@@bigguy130 i'm gonna be honest here. I am not too materialistic to the point of not wanting to ever let go of the stuff i own. I mean, i kind of don't want to, but if i have to it's okay. However.... i really, really fear death because i genuinely do not know what comes after it... i don't know if i will be a ble to think again, to have joy, i don't know if afterlife exists.... i really, really want it to be a thing, but i don't know if it is.. that's basically why it scares me so much
your use of indexing is so very considerate and appreciated.
FANTASTIC interview Tom
My life has changed because of you tom! I have read 400 books & lost 60 pounds. As a form of gratitude I made a vIdeo on you. Thank you :)
Gosh! I never knew reading that much could make someone lose weight!
What a waste of time, why would you read 400 books..
Incredible person reading this, you have everything there is to succeed in life, whatever that is for you. Go after the life you truly want NOW! ✨
I believe in you! Love - Nat ❤️
Out of this world episode! As usual😊Thank you!
Thank you for all the hard work and for sharing this with us!
Wow!!! This is insane to think about and sooo exciting!!! It made me cry… Maybe one day I’ll be able to get a new spine?? 🤞💪🏽👍🏼 I loved every minute of it..Thank you so much for this clip…
One thing is sure, someday you won’t need a spine.
I can sense a vampire vibe, on the look and smile of Dr David
Amazing David and Tom as the best interviewer !! thanks
Love it Tom. How he did not allowed Dr David to talk on his level and bring the whole discussion to meaningful to normal people!! As always this is what makes whole conversation so engaging
I think age is a mind thing. I know it sounds weird, but if u don't worry about your age that helps not focusing on it. ❤
If that was true, the millions of people in history who also believed that wouldn't have died
@@themitchellbrothers it's one of the factors. Can't be the only one.
I see what you are saying and maybe but not when you NEED to know these things. I know you are not suggesting ignoring age but I know some will perceive what you have said as that or even something even more off topic. Yes age is only a number. 👍
Nah.....sorry.
Absolutely agree indeed…..!!! However one cannot expect to continue eating the common American diet full of junk food. Loaded with refined sugars & playing couch potato. Plus expect to look n stay young forever obviously 🙄
I literally was just going to suggest having David Sinclair on your show again because if anyone can solve longevity it is him!! and Tom I’m pretty sure you’ll get your wish of living longer if David Sinclair has anything to do with it!!!! I’m so glad you guys are doing this podcast .. while I love his lifespan podcast I find it easier to absorb information through Tom’s podcasts over the lifespan podcasts that I have recently been listening to. I haven’t listened to this one yet as I was overcome with joy and wanted to comment right away when I saw the two of you have gotten together again!!
He has a podcast. They mentioned, there will be 8. UA-cam has 4 right now.
Always amazing to see your shows Tom and David Sinclair is always interesting.
Just awesome! Thank you so much for sharing this!
I love it when David Sinclair comes on. He’s all about longevity. Amazing, please keep bringing him back
Why does he look like he uses botox?
@@2drealms196 I think not, but even if so, what a meaningless comment.
*Diet, sleep and exercise* 🙏❤️
Hell yeah!! 🔥
Been waiting for this for so long Tom!
Great episode by Tom again that I'm watching with a cup of tea right now
Reminder to myself:
10:15-12:00 Sirtuines (proteins) = hide the parts of the DNA that are unimportant for one particular cell, because all cells consist of the same 6feet of DNA but not every part of it is relevant for every cell. This hiding-process is relevant for survival.
It just blows my mind how our body works and how we have learned so much about it!
David Sinclair is the future indeed. His book is amazing!
Thanks Tom for a great job all together. But considering the immense expertise of your guest, I wish him more freedom in his talk than constant interruptions and your restrictive templates of questions. I liked your former episodes where you were more quiet and reciever than mediator of the conversetaion too actively.
I felt that way too for the first 10 min or so. But then he dialed the interruptions back. It seems like he wants to set the stage for his audience to understand the rudiments of a pretty complex subject.
I have been doing intermittent fasting and eating keto for about 3 years. Started taking NMN and resvereratrol, I feel like a machine!!! Never felt better!!
What is NMN?
This is amazing!Thankyou for the video! 😀
The dude is insane
I don't know; on my maternal side, my great grandfather and grandfather lived to 106, and on paternal side, my grandparents lived to 97+. My uncle at 82+ still climbs his rooftop. I have longevity in my blood. I just want to optimize my healthspan.
Agreed
and your parents?
@@360.Tapestry My parents and siblings all have metabolic issues and diseases due to standard America diet. I tried to convince them to go low carb but to no avail.
@@TheShumoby that's very unfortunate to hear. all you can do is be that beacon for the day they are ready to listen
@@360.Tapestry a
Thank you so much for everything gentlemen.
Just discovered your channel and I'm so glad I did. You're such a great communicator and your guests are all trail blazers.
I'm going to be making changes to my life and diet as well!
To the *incredible person* that's seeing this, I wish you all the best in life❤ don't over blame yourself, accept things and go forward. Don't let others define what “success” is for you. Get up, learn the skills needed and get after it, all the keys to a happy life is in your hands. Keep pushing.
Very informative!! I am looking for the day someone can explain why menopause exist and how to keep the body from experiencing it!!
It exists because once your body becomes too old to raise children there is no need to be fertile or experience menstruation any longer. Now you know!
If I’m not mistaken a female body has a certain amount of eggs that if don’t get fertilized the body releases each month with period. Once there is no more eggs there’s Nothing to release and here comes the menopause. That’s my understanding but I might be wrong.
It is a natural process and we have to tolerate 😒drink herbal teas to fight it
The reversed it in mice ☝🏾
@@mahgul8414 , I don't think it should be natural. The body shouldn't cause discomfort. I'm sure if more doctors or scientists studied it a relief for most women would be appreciated. My experience has been it's just a process and try hormone therapy! I decided this year at 54 to try natural supplements some have worked. And eventually they stop as our bodies change hormonal . I've talked to several women and many of them suffer in silence.
How wonderful to be a scientist. Your brain is always in motion, inventing, experimenting and achieving to levels beyond expectation which is so satisfying
Tom you are brilliant thank you for all that you give. ❤️
We want to hear Dr. Sinclair talk, this guy Tom wants to hear himself sound smart and it takes away from the quality and education of the podcast. For future podcasts, advice, shut up and let the experts talk.
I finished a 39 hour fast today. I’m going to try and keep pushing it further.
Great knowledge📚!! Thanks Dr.
This was excellent thank you!
Dr Sinclair looks even younger and energetic than his last time on Tom’s channel! Appreciate this video so much ❤️
It looks like he uses botox.
creams, botox, hair dye...the key is "looking younger" and there's nothing wrong with that.
in one of J.R podcast he does mentioned he dyed his hair as a "curiousity"
@@cginternationalconsulting2417 to cover the grey,in his book he said he didn’t have any grey hair, now I know why,having said that his knowledge of ageing is excellent
Urine
I've been on track with diet for about 4-5 years. I cold press Kale, Spinach, carrots, and celery, with moringa powder most days, followed by 1 meal around noon every day. It has transformed my life, I feel 25 at 59 years old. I do 100 pushups every other day, and at least 50 curls (20lbs) per arm other days. My main issue is drinking a lot of beer every day too, and I smoke cigarettes, and marijuana. I simply won't lose belly fat as long as I keep on with the beer. I do believe aging is controllable.
Lol this comment started out great but then you fell off a cliff
@@spruxo yeah, I get it.
I love the honesty! Thanks for sharing!
Now imagine you without the beer!!! I recently stopped doing drugs and drinking overall and it’s been fantastic. I was able to do it by outgrowing wanting it, instead of wanting to but not indulging, which makes all the difference.
@@chefmj_adventures thanks, candor is a strong point.
Thank y'all so much dearest 🌹
Y'all such an inspiration 🥰
Appreciate y'all from the bottom of my heart 💖
Be Blissful Eternally 🙏👼🌈
Amazing love to see all this information thank you both for hard work there is hope.😀
Wouldn't an increase in mitochondria from metformin accelerate aging/oxidation?
First, i skipped most of the video as nothing new really. I heard the same from David one year ago. Just have a healthy lifestyle that's all we have as always been.
Then the fact that he mentioned that gene therapy will be out of reach forever due to insane price tag, that really killed my hope and im in my late 30's. I have been following longevity trends almost 15 years now and frankly i feel like a serious life extention will not happen in my lifetime.
What do you think of stem cell therapy?
Stop being so negative jesus man 🤣💀
Gene therapy is simply technology. Since when does technology stay expensive forever?
@@mouthpiece200 since there iis demand for it
Thanks for this Tom ! Dr David always looks so healthy and youthful and You are looking really good too .
He uses botox and seems to have little body tension.
Exceptional, one of the best interviews.
Four things, be hungry, NMN, Metformin and resveratrol. That's the secret 🤣
Before I began IF , once my hunger reached a certain level I became my body's "beach" ( rhymes with ditch, actually). Ever since I became a regular faster, even when not fasting regularly, it's as if I've shown my body that I'M the boss and hunger never feels really bad anymore , like it once did.
I am falling in love with omad lifestyle.
It gets easier with practice. I remeber the first day I did a 24 hour fast..I nearly died. mow I can do easily.
@@magdal3nam.353 you won't get enough protein. Do it 1-2X week only. Rest 2 X day
@@momentumstocks3493 yes I am testing every way :). Thanks for sharing.
This interview was amazing
Absolutely amazing epidode
How to reverse aging:
1. Don't get married
2. Don't have kids
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Nice talk. Each time tom talks I feel empowered..
Didnt know this guy before.. now he is the number 1 person in the world i want to follow and see/watch everything
I think this pandemic has taught people the importance of multiple streams of income, unfortunately having a job doesn't mean security rather having different investments is the real deal.
Having some kind of side hustle or alternative way of making money, in addition to a regular job, is really important. Not just true now, but it was true 20 years ago. There hasn't been such a thing as a "secure job" in over a generation. Learned this the hard way.
Most people remain poor only because friends and relatives stopped them against Investing and trading Crypto while the wise ones kept investing and growing higher financially.
Seriously Crypto is a life changing business which can change any one.
General the world is now aware of Crypto trade
investment in Crypto now should be at the top of every wise individuals list
@@witzemacher783 You are right the market is profiting if you are really a good broker or account manager
@emilia patricial Trading with the help of a professional broker is the best way. As for me I work with a trusted and a sincere broker sir Chris Pulver who manage and return profits why not try and invest with him
Wtf is going on with this commentsection lol
Wondering the same thing lol attack of the bots
I thought the same
Love the little section highlighter! Great touch to the product!
Awesome! I definitely want to live over 100, health!
*WHY DOES HE LOOK HIS AGE??? IF HE’S ADVISING US HOW TO GET YOUNGER ? WHY DOESNT HE LOOK YOUNGER??*
He’s 90.
Very good question!!
“Every soul will taste death. Then to Us will you be returned” (29:57)
Damnit! You guys are right, but I don't wanna do it! 😭😭😭 Thank you so much both of you! We are so lucky to live in a day and age where this knowledge is available for us to choose. Thank you so much!
So interesting and exciting!!
I want to look 25 again.
Will never happen
@@neromachiavelli5670 it will happen😠
David Sinclair promotes a plant based diet!! 💪🌱❤️
Yes, go vegan!! For the planet too
21:00 I’ve been thinking Tom ends too many sentences with uptalk but this is another level.
I just saw an news article featuring a photo of David Sinclair from 2017. He looks 5 years younger now than he does in that picture.
Rise and shine, it's "becoming biologically immortal" time! 💪😁 Stay fit, stay healthy... AND YOUNG FOREVER!!
Humans, dolphins & whales are the only 3 species on Earth NOT genetically (DNA) programmed for physical death. . . It's just been a false belief. . .
This guy literally makes me look forward to the future when he starts talking
This needs more praise and likes
Tom you are doing great job
The guy looks like a super villain . I don’t trust it