Why Do Bacteria Move Like Vibrating Chaos Snakes?
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- Опубліковано 3 січ 2021
- This video was sponsored by Skillshare. The first 1000 people to use the link will get a free trial of Skillshare Premium Membership: skl.sh/journeytothemicrocosmo...
Bacterial flagella are very hard to spot in our footage, but we see evidence of them in almost every single one of our videos. The question is, how do they work, and are they different from the other flagella we've discussed?
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SOURCES:
academic.oup.com/femsre/artic...
www.ks.uiuc.edu/Research/flage...
www.pnas.org/content/112/32/E...
www.britannica.com/science/fl...
jb.asm.org/content/182/10/2793 - Наука та технологія
"Vibrating Chaos Snakes" is an awesome name for a band.
Hells y3s
Or a laxative.
I'm thinking speed metal.
😄😄😄
Chaotic BuzzSerpents is better
I see the phrase “vibrating chaos snakes”, I click
that why you get hooked easy
@@KurtCollier ayy
i just hope they're safety strings and not danger ropes
....and try to use it in a sentence today.....
Eukaryotes: I whip my hair back and forth!
Procaryotes: *Heavy metal windmill hair* - *forms mosh pit*
Lmao correct
Bahahahaha, that's funny.
Hell yeah knowing that my body's become a massive mosh pit will probably make me feel less terrible when I'm ill
“Vibrating chaos snakes” are definitely gonna feature in my next D&D campaign.
Wait -- just wait a gosh darn minute. Are you telling me that even for *bacteria* it's "Lefty loosey, Righty Tighty"? What a planet we live on
One turn drives straight, another turns the vessel.
The first time I heard that phrase (I am not American, nor is my first language English) I failed at demonstrating a left threaded lock nut correctly...
Because, of course, I first wanted to loosen it turning left.
The whole planet's righty tighty left loosey
@@Ezekiel_Allium That depends on whether you perceive the north or south pole as the "top" of the planet. .
It's cool how their size and the properties of water make flagella better for bacteria and fins better for fish. Like this channel said before, at the small scales water is so much more _syrupy or thick_ that if you stop propelling yourself, you will just stop suddenly.
I want to know how they know how their flagella work if you can't see them or dissect them
@@nicholasgeere5125 yeah! In the video hank mentioned briefly something about the 2 separate kinds of flagella, some going in circle and back and forth, and they found out how they moved by taping them down, with the spinning and stuff. I can't imagine how this was done, especially back in the olden days with less tech.
Electron microscopes and X-Ray spectroscopy is how we know the shapes of the molecules inside microbes today.
@@SquirrelASMR with FLEX TAPE you can do anything!
@@nicholasgeere5125 Dyes and stains. Certain slide stains will colour some bits more than others, and with the right magnification, you can see into the transparent cell membrane to discern the different types.
Using “vibrating chaos 🐍 “ in my biology class now during microbio
I love the mental image of taping a flagella down and watching the bacteria spin in confusion. How do you even?
I just imagined the guy in charge of doing the taping 😂
very precisely.
I looked at the sources briefly and think the video got it wrong, the bacteria were immobilized not the flagella
With very, very small pieces of duct tape
In the 80's I was reading a Transformers comic and giggling over the stupidity of their evolution of "naturally-occurring cogs, gears, and wheels" Yeah... who feels silly now? This nerd.
Look for animations of how ATPases (the evolutionary root of flagella) work. Truly wild and huge. Hard to image how that comes from soft, squishy, fragile structures with the consistency of jello made from elaborately but repeatably folded strings.
@@b.griffin317 the video just explained that the bacteria flagella has nothing to do with ATP so why are you bringing that up when hes literally not talking about it?
@@nom6758 bacterial flagella and ATPase are structurally similar and evolutionarily connected. Both are the only two known protein motors that use ion gradient to move instead of ATP
@@nom6758 Similar mechanisms are deserving of comparison, are they not? Simply because they are different doesn't mean they cannot be likened to one another. Each instance is an example of evolution having created fascinating mechanisms that resemble human manufacturing. ^^
For those looking for a video on ATPase/ATP synthase I'd recommend this one from a channel I discovered yesterday: ua-cam.com/video/lUrEewYLIQg/v-deo.html
"The 7,800 RPM Motor that Powers Everything You Do"
Can we expect “flagella fan club” merch in the future?
i hope not. for the planet‘s sake
@@kisnpisn4919 No, we need this!
Remember those old remote controlled cars that go forward in a straight line but they turn when you put it in reverse? It's kinda like that. 💕
My microbiology professor used that exact example in class
Hank: the Bob Ross of tiny vibrating chaos snakes
Guys, “flagella” and “bacteria” are plurals. The singular versions are “flagellum” and “bacterium.”
THANK you! Signed, an annoyed zoologist
Love getting shrunk down for these videos!
I've always heard that nature never created a wheel. This essentially seems like it's almost there. They managed to make a hub.
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Exactly & I still don't understand how, for a wheel to exist, the two parts need to be completely separate or else turning would rip the fleshy bits apart.
Molecular wheels are easier since on that scale things don't really touch.
@@sirjamesfancy bacteria dont have flesh
@@animationspace8550 I was referring to living things in general
The creativity of this science channel really makes it epic
I think it should be noted that the effects of the rotating the flagella one way or another is dependent on the specific bacteria. For example E. coli runs when the flagella rotates counter-clockwise and tumbles when it rotates clockwise.
Also some bacteria like those of the genus Vibrio have a bidirectional flagellum that moves the organism forwards or backwards depending on the rotation
I just posted my question on the direction of bacterial flagella rotation too and your comment kinda answers my confusion on the direction! Great job! Epar321!
The Flagellation Fan Club may get misunderstood.
The bacteria at 6:00 look like the milky way
That's so cool!
the molecular drivers behind their chaotic and straight movement is also really cool! During chemotaxis, the bacteria will go straight as long at the receptors for the chemical signal detect an increasing concentration. And yes, I don't just mean big, I mean increasing. If the concentration of the chemical attractant stays the same (i.e. the bacteria is moving roughly perpendicular to the direction of the source), it's receptors will become tolerant of the signal. This stops the straight swimming and causes that chaotic tumbling into a new direction, until the receptors detect an increase and the straight movement begins again!
Through this cycle of swimming, becoming tolerant to a signal, then tumbling, reliably directs bacteria to the source of an a stimulus, even though they don't know where the source is, and don't have any mechanism to consciously "turn" in a direction
So many beautiful shots I couldn't help but take screenshots. So detailed
Thanks for the episode
Will Andrew Huang ever release the music for this channel on Spotify? It’s chill as fuck
thanks for putting videos out as often as you do, gang. i like to save up microcosmos adventures for when i have migraines and can barely tolerate noise, but need something to distract me- you guys really get me through the garbagetime before my meds kick in. :~) love what you do!!
Thanks again for a fantastic video!
Nice! I've never seen the flagella "live" so to speak, only when using a flagella stain.
Someone put gmod ragdoll sounds to this.
LOL I can hear the physics collisions already.
You guys genuinely make the best content on UA-cam
Wonderful video!
I used to work in a laboratory and watching spirochetes under magnification was always a blast. Great video!
This is pretty much the only channel I watch in normal speed :p Gracias, as usual
Commenting for support.
I'm so happy you guys made this video! I know it's hard to get the footage, but it's to cool not to discuss!
Enjoyed your video and I gave it a Thumbs Up
Just in time to watch before sleep. Thank you all!
i've always wonders how flagella work at such a tiny scale.
Look for animations of how ATPases (the evolutionary root of flagella) work. Truly wild and huge. Hard to image how that comes from soft, squishy, fragile structures with the consistency of jello made from elaborately but repeatably folded strings who's 3D shapes are precisely locked together and held in place and shape only by the electrostatic pressure of water.
@@b.griffin317 you really still believe in evolution did complex things like that lmao
@@howtodoit4204 You’re in the wrong channel. Nonsense isn’t welcome here.
@@miko5167 this channel isn’t yours slug head
@@howtodoit4204 No, but I doubt anyone wants your unscientific nonsense here. This is a science channel after all.
Remember fellas it's not about the size of your wiggly appendage. It's how you use it
inspiring, thank you
To be fair, not having an adequately massive wiggly bit prevents you from stumbling around when you perform a helicopter impersonation..
I would love to see more on bacteria like this on this channel.
Huge fan of these videos. I'm a bit obsessed. I'm so stoked about all the content y'all've made.
Side note: when does this become a sleep podcast? Your voice has trumped the Sleep with Me guy as most wanted sleep podcast voices.
Thanks again
Your channel is gonna blow up soon, love this content, kept it up. Also, a minor but important criticism, you should use the language “evolutionarily advantageous” as opposed to “evolutionarily planned” because it more precisely conveys the nature of evolution and the principles of Darwinism to people who don’t understand. As scientists it sounds rather eloquent and like good writing, but many people who aren’t educated in the sciences ask questions like “how did things decide what to evolve?” in complete sincerity.
I just bought a 4k tv and can't stop going back to older episodes and rewatching everything. You can't truly appreciate how beautiful the microcosmos is on a phone.
Every part of this episode is beautiful, from the title to the music, this was an incredible experience the whole time, thank you
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It's always a good day when Journey to the Microcosmos uploads.
These are always so good XD
I love this channel.
Another great episode of Bacteria ASMR!
Seeing flagellates nearly as small as bacteria was not something my mind was prepared to process.
I think the obvious question is: if looked at from above wouldn‘t we look just as chaotic?
Ofcourse the also obvious answer is 42.
Vibrating chaos... That makes me think of browninan motion. You should do a video on this. It's pretty cool when you realise that everything is vibrating quite a lot, even if it's not alive.
Vibrating Chaos Snakes is the most interesting phrase and most interesting video title I've ever heard.
to move forward run It's counter clockwise , not clockwise . so flagella bend at their hooks to form a bundle that propels the cell to move forward.
Flagellar rotation in clockwise direction disrupts the bundle and the cell tumbles.
This is my favorite ASMR channel
So they aren't like "winding" up , then releasing it to move?? This is so cool! I'm going to look closer into this 🤩 thank you!
you guys ever think about getting an scanning electromicroscope to go in even deeper?
No video then.
@@b.griffin317 just lower framerate. And i dont think moving bacteria are doable in SEM. But on the other end. You can zoom on the flagella and see what its surface looks like. (black/white ofcourse, as colour doesnt exist in those sizes.)
How did they dissect a bacterial to figure out how it works
They zoomed in and did chemical tests probably, not literally cut one open. You can cool the plate down to slow them and use an electron microscope to zoom into the flagella
I held a lecture on cell membranes and rotary molecular motors incl. Bacterial Flagella on Tuesday and you release this video on Monday. I have 2 lectures on Cytoskeleton and Linear Motors coming up. So if you could maybe release those videos not so last minute. Thank you!
Why is it that when I'm about to go to sleep a ton of videos from my favourite youtubers come out
You should look into acne bacteria. How, why and what does it look like under a microscope
this video covered parts of my homework assignment from 2 weeks ago so perfectly it's kinda eerie😂😂😂
Hank, you are a giant dork, and I love it! 🥰
well, i definitely learned something new about Bacterial Flagella.
Seriously, though... i wasn't aware that your microscopes could zoom in that far!
i wonder if any of you attempted to find or look at Virons?
I've often wondered that exact thing.
that is eye-popping!!! I never thought living creatures can have rotation parts like motors!!!
it's so wild that bacteria mastered the concept of exploration vs exploitation!
thank you for the skillshare Premium 😊
You need a part two on this subject including the amazing evolution of flagella
The is nothing called evolution totally made up blind process
Amazing
Thanks.
I tried to show the kids down at school my flagela, and they called the cops!
Comments for the chaotic algorithm.
This soundtrack never ceases to amaze me
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Coming here after the crazy cause I can’t sleep. Thanks for the soothing in the sea of chaos. At least this is soothing chaos
Keep those DIC picks coming
"Best. Video. EVER!!!!!"
--Vibrio cholera
WAIT! How did I not know until just now that this is Hank Green 🤦♂️ I've been watching Journey to the Microcosmos
forever!
Vibrating Chaos Snakes sounds like the name of an old school gang who snap their fingers against their rivals The Shaking Disorder Vipers in a musical.
Love the "microtubes surrounded by salmon brain". Took me a while to figure out that it was not salmon brain afterall.
What happened to the extreamly soft calming voice you would use? Slow and low! I really enjoyed that
> sugar detected
> engage clockwise rotation
.
.
> press "anti-clockwise" to doubt
I can't tell you how many times I ask "hmmm... does this move like a vibrating chaos snake?" So glad I'm not the only one. People are starting to wonder about me....
More diagrams please!
Would be nice if your Master of Microscopes had access to a 1000x or 1250x scope so we could get a good view of these things spinning around. Biological motors do not exist on the macro scale and thus it's incredibly hard to see nature generate infinite rotation.
I'm never this early looks like I get skillshare for freeeee
This is amazing. I think you should have compared them to electric motors, though, not an engine. They are biological inrunners!
Gee willikers, Batman! I’m early for some Microcosmos!
Bacteria: *start vibrating*
UA-cam video: *Confused screaming*
Do have a spatial frequency spectrum of flagella movements analysis? How it looks like and changes cross types, environment conditions? If no, would be good field for the study. Not too complex one, but might be useful.
Random motility. Describes my life so far.
they just vibin
Hi I happen to watch this video for my microbiology test tomorrow and found there’s a inconsistency from this video and my textbook on which direction a bacterial flagellum rotate to make the run and tumble. My textbook says “counter-clockwise for the run and clockwise for the tumbling “. I am curious now. Please let us know. Thanks.
B. Cereus sure felt like a vibrating chaos snake in my stomach when I had it.
The description of the flagella going clockwise vs anticlockwise amazes me. Its hard to understand how the effects are so different. I kinda want someone to make a life sized one to understand the microfillaments working differently
You’re like Mr. Rogers with a microscope 😄❤️❤️
Huang's back on form
Why would anyone dislike this?
Science is awesome.
The motor that spins the hook on the bacterial flagella is clear evidence of intelligent design. An example of irreducible complexity.
Not to mention the ATPsynthetase in mitochondria are just bacterial flagella working in reverse. In that way, the biological machinery of bacterial flagella not only helps bacteria find food, its one of the fundamental machinery that keeps life going.
How to move forward? Step on the gas pedal.
How to turn? Step on the reverse pedal and let chaos handle the rest.
Hank: "... with a lot of magnification ... you will see these faint lines coming off of them"
My computer: "not with this screen you ain't"
So I just looked at bigger fuzzy snakes having a dance party