How does Narcan (naloxone) Work?

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  • Опубліковано 15 вер 2024
  • How does Narcan (naloxone) Work? Pharmacology for Nurses
    Narcan (naloxone) is an opioid antagonist which means it will move any opioids currently sitting in a receptor site - out, and Narcan will take its place to prevent opioids from binding. The opioid that was originally sitting in the receptor site functioned to change the cell activity. Opioid receptor sites can be found in the brain, nervous system, and intestines. The ones we are concerned with here are the ones in the brainstem as when opioids connect to those receptor sites, the drive to breathe decreases.
    You may come upon a patient who is breathing very slow or not breathing at all. If Narcan is available, you can administer it. It will not harm someone who has never taken Narcan and it may potentially save a life.
    Narcan is given every 2 to 3 minutes if there is no response and in your kit, there will be three doses. If the patient does respond to the first dose, they may wake up agitated because all their pain is back. They should stay awake for 2o to 60 minutes before the Narcan is depleted, leaving the opioid receptor sites free for the opioids that are still circulating to bind. As opioids have a longer half-life, many doses of Narcan are usually required.
    As opioids have a longer half-life, we often need to use Narcan more than one time on the same patient.
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КОМЕНТАРІ • 83

  • @toyalambeth366
    @toyalambeth366 Рік тому +6

    Living in Las Vegas I think we need to blast your video on the billboards. Everyone needs to have narcan on hand to help out with the opioid pandemic. Thank you!

    • @MeaThreattoDemocracy
      @MeaThreattoDemocracy Рік тому

      I'm inclined to believe with Narcan, the cure is worse than the disease.

  • @lilcxtofficial1264
    @lilcxtofficial1264 2 роки тому +6

    You’re the kind of non-judgemental person I feel like would incubate an incredible conversation. Thank you for the video, it was an enjoyable lesson 🙏

  • @Cyclegladiator
    @Cyclegladiator 3 роки тому +15

    When you mention that all of the pain a patient previously had will come back immediately, you should also remind that the patient will be in full-blown opiate withdrawal which is most likely the reason for hostility

  • @HollieMM
    @HollieMM 2 роки тому +12

    When I was in grade 10-12 there was an opioid pandemic. I graduated in 1999, I'm 40 now. And thankfully it never happened to me but it is still happening. I recently picked up a kit from the pharmacy. I hope I never have to use it. Thank you for the video!!

    • @NurseMinder
      @NurseMinder  2 роки тому +2

      I hope you never need it, but having it is awesome in case you do

    • @jamesclinesr2511
      @jamesclinesr2511 Рік тому

      It wasn’t half as bad then as it is now. I am 43 I graduated in 98 I don’t remember no opioid pandemic down at all media people did it, but it wasn’t. They weren’t dropping dead like they are now not even close.

  • @BigBadBalrog
    @BigBadBalrog 4 місяці тому +1

    What a beautiful video. Thank you for dispelling doubts and questions about a highly stigmatized topic.

    • @NurseMinder
      @NurseMinder  4 місяці тому

      Thank you for your comment, and time

  • @mannystarz1644
    @mannystarz1644 Рік тому +4

    I’m usually never into this type of stuff but this was so interesting to me. The biology behind it and the history is really cool. Hopefully I don’t have to use this information in the future 😂

    • @NurseMinder
      @NurseMinder  Рік тому +1

      It is pretty cool! Thank you for sharing

  • @tuskiomisham
    @tuskiomisham 9 місяців тому +1

    3 years on this is the only youtube video I can find on narcan's functional mechanishm. Thank you!

  • @AdamGrier
    @AdamGrier 2 роки тому +2

    You diving on top of the patient is badass

  • @pirate0bloodyskull
    @pirate0bloodyskull 2 роки тому +4

    This video was so informative. It answered every question I had about naloxone.

  • @crod8387
    @crod8387 Рік тому +1

    I'm learning about hypertension so that I can get off the meds. I find your videos very informative. Thank you!

    • @NurseMinder
      @NurseMinder  Рік тому

      Great! Keep your healthcare team involved.

  • @daveamoroso
    @daveamoroso Рік тому +2

    Very Good Explanation.. Good Job...

  • @janana6138
    @janana6138 3 роки тому +9

    Very informative, I’ve always been curious and this in depth explanation has really explained things. I thought your personal experience was interesting as well. 👍

  • @lloydpenney6689
    @lloydpenney6689 2 роки тому +2

    I got a Naloxone kit because I go to festivals and other events during the summer and I wanted one handy. (my brother-in-law lost a nephew to a fentanyl OD.) I'm glad I watched your video now I understand a lot more on the drugs work and the responses to expect. Thanks for doing this.
    Y Penney - in Ontario

  • @Nan-59
    @Nan-59 2 роки тому +2

    That's a fabulous kit!! In the states, our kits come with only 2 doses, and none of the extras! Gloves, breathing device, etc!

    • @NurseMinder
      @NurseMinder  2 роки тому

      Oh wow! I always find it fascinating how different places do things

    • @ValFromMontreal
      @ValFromMontreal Рік тому

      @@NurseMinder In Quebec too, only two doses. Thanks for the video!

  • @lbabytutorials4852
    @lbabytutorials4852 2 роки тому +4

    I overdosed on heroin one time and they put Narcan up my nose. I swear to God when I woke up it was like I had so much energy. I didn’t know why everyone was around me staring at me. It was so crazy, I want to know why Narcan put me into rapid withdrawal. My skin started crawling, I was sweating, it was hell. So I want to know what’s in Narcan that makes someone that overdose is going to withdraw

    • @NurseMinder
      @NurseMinder  2 роки тому +2

      Thanks for sharing your experience. When Narcan is used, it will look for any narcotic and remove the narcotic from a receptor site. And then Narcan will block that site so the medication cannot find. It is as if you have not taken any medication once Narcan is on board. Problem is Narcan only last for a short time, and then as it dissolves the medication will again connect into the receptor. So it can be a up-and-down ride

  • @pixie1768
    @pixie1768 3 роки тому +1

    No idea how I got to this video but glad I did. Thanks for sharing the info. You are a great trainer too!

  • @Istandal0ne1
    @Istandal0ne1 Рік тому +1

    This video is priceless! Thank you Nurse!

  • @brendanfogel4573
    @brendanfogel4573 3 роки тому +2

    It’s crazy what scientist have done

  • @PinkJoy143
    @PinkJoy143 Рік тому +1

    Wonderful job, thank you so much. This may be a silly question....is it possible to give it to bring yourself back? Like as you feel yourself going down. Is that unheard of? You addressed a terrifying, shameful, and secretive subject un~biased with ease in quirky

    • @PinkJoy143
      @PinkJoy143 Рік тому

      with ease in a quirky and thorough delivery.

    • @NurseMinder
      @NurseMinder  Рік тому

      Yes you can give it to yourself. Its one of the benefits of having the kit

  • @leejganderson7827
    @leejganderson7827 2 роки тому +2

    Thank you for this more simplicity way to understand Narcan
    Peace
    *Have a Safe*
    *Happy Holiday Season*
    👍😉🍀👍😉🍀

    • @NurseMinder
      @NurseMinder  2 роки тому +1

      Appreciate the feedback. Happy holiday season to you as well

  • @westfield90
    @westfield90 Рік тому +1

    Thank you. So well explained.

  • @TheFlatEarthChannelcom
    @TheFlatEarthChannelcom 2 роки тому +1

    Saved my life last night

  • @maliksutton6634
    @maliksutton6634 3 роки тому +1

    Hi Mrs Tammy, I enjoyed watching you explaining Narcan also known as Nalcoxone and how they can be a pain reliever for Opioid.
    I found this topic interesting because I am a Human Services major at college and have taken some courses which explains addiction, pain relief, aging, substance abuse and so on.
    Can Narcan make a person addicted just as if it was a prescription or another drug.
    Also, I checked out your mask fog prevention video an hour ago and found it helpful to learn about how to reduce foggy glasses.
    I left behind a link to a product that may help because I purchase mine's last Monday and it has made a difference in wearing a mask to where I can breathe better and less suffocation.
    I also have some other tips on how to reduce foggy glasses.
    1 Use good anti-fog product.
    2 Place glasses on top of the mask.
    3 Fit mask to your face.
    4 Use medical tape to create a seal.
    5 Absorb the moisture by inserting tissue inside the mask.

    • @NurseMinder
      @NurseMinder  3 роки тому

      Thanks Malik. Narcan does not create an addiction. Narcan has no effect on someone who has no opioids on board.

    • @maliksutton6634
      @maliksutton6634 3 роки тому +1

      Thanks for the clarification Mrs Tammy, I really appreciate it.

  • @roland.j.ruttledge
    @roland.j.ruttledge 2 роки тому +1

    great info, many thanks UK

  • @robbymann5839
    @robbymann5839 2 роки тому +1

    Cool
    Thank you

  • @orangeguy8859
    @orangeguy8859 2 роки тому +1

    I’ve always wanted to know what other things can narcan take care of

  • @kenbrownfield6584
    @kenbrownfield6584 2 роки тому +1

    Can you do a vid on how to use the nasal spray please

    • @NurseMinder
      @NurseMinder  2 роки тому +1

      I don’t have access to the nasal spray for demo. If I get a kit, then I will

    • @kenbrownfield6584
      @kenbrownfield6584 2 роки тому

      @@NurseMinder Thanks

  • @williamkeech9359
    @williamkeech9359 3 роки тому +1

    Would it be legal for me, a citizen of North Carolina, to carry Narcan in case of an emergency where I have to use it to save someone?

    • @NurseMinder
      @NurseMinder  3 роки тому

      It is handed out here free no questions asked

    • @Nan-59
      @Nan-59 2 роки тому

      Yes! Please carry Narcan! You could save someone's life! I've been carrying for years.

  • @mwoods4608
    @mwoods4608 2 роки тому

    my son needed 4 doses last night

    • @NurseMinder
      @NurseMinder  2 роки тому

      Yes it is commonly needed more than one time. I hope all is ok

  • @Earthboundmisfit1
    @Earthboundmisfit1 2 роки тому

    Can you explain accutane

    • @NurseMinder
      @NurseMinder  Рік тому

      Did you find your answers? I have not researched accutane yet

  • @spongebobstiddies2960
    @spongebobstiddies2960 2 роки тому +1

    of course the first time you needed to use narcan was in downtown winnipeg😂

    • @NurseMinder
      @NurseMinder  2 роки тому

      Familiar with the area are you 😁

  • @MikiBreki
    @MikiBreki 3 роки тому +1

    Cool stuff

  • @raebennett1174
    @raebennett1174 Рік тому +1

    When someone is overdosing there no way in hell you got the time to take a wipe and clean the vile

    • @NurseMinder
      @NurseMinder  Рік тому

      I get it. It feels like a stressful situation and that every second counts, but you have time. Research shows we can go up to 4 minutes without oxygen before damage begins

  • @JB-xl3ix
    @JB-xl3ix 3 роки тому

    me at 2am

  • @RedLoveShow
    @RedLoveShow 3 роки тому +1

    if any one need Opiod to forget pain. It's much better to smoke weed than opiod.

  • @kimberlycararillo2475
    @kimberlycararillo2475 Рік тому +1

    Narcan will bring the dead back to life

  • @r4k00n5
    @r4k00n5 2 роки тому +1

    Working on a song.
    Woke up with shit in my nose
    Smell was stuffy and i needed to blow
    People hold me down tell me its okay
    This is gonna be an interesting day
    Ambulance rushes me away
    Make small talk the nurse, name was Trey
    Worked in biomedical
    Told me my weed had fentanyl
    Arive at the hopital, feelin blue
    Wondering if my suspicions are true
    That my dealer is
    A massive fucking piece of shit
    They wheel me to my new apartment
    Nurse reaches in the glove conpartment
    Touches my face and checks my eyes
    Holy fuck I want fo die
    Parents arive, blank look on their face
    Tell me I'm the family disgrace

    • @NurseMinder
      @NurseMinder  2 роки тому

      Sounds like you have had an experience

  • @jb1611
    @jb1611 2 роки тому +1

    u bad i’m ngl