How Moderna And Pfizer-BioNTech Developed Vaccines In Record Time
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- Опубліковано 26 сер 2021
- The decision to pivot an entire business to focus on the coronavirus is an obvious one in hindsight, at least for Moderna, BioNTech and Pfizer, which succeeded beyond anyone’s expectations - and will reap billions of dollars in sales of their vaccines this year alone.
It wasn’t such a clear decision in the early months of 2020, though that’s when Moderna’s chief executive, Stephane Bancel, and BioNTech’s chief, Ugur Sahin, starting turning their ships, they told CNBC in interviews for this documentary about the vaccine race, produced by CNBC senior health and science reporter Meg Tirrell and senior digital producer Sam Rega.
“The night that China locked down Wuhan, I’m like: ‘When was the last time I know a city has been locked down because of an infectious disease?’” Bancel recalled. “And what goes through my mind is: what do the Chinese know that we don’t know?“
Bancel said he awoke sweating at 4 a.m., realizing, “Jeez, there’s going to be a pandemic like 1918.”
For Sahin, it was reading a paper in the Lancet in late January describing the outbreak in China.
“I did a number of calculations, fast calculations, and realized it had already spread,” Sahin said. “And it was clear that it was already too late to stop the disease.”
But he was convinced BioNTech, then focused mainly on personalized cancer therapies, may be able to do something. His company reached out to Pfizer, he said, proposing to work on a vaccine for the novel coronavirus using the same technology, messenger RNA, on which they’d already partnered to try to tackle the flu.
“We had the first contact a few days after starting the project,” Sahin said. “At that time, Pfizer was not yet interested.”
Albert Bourla, Pfizer’s CEO, confirmed Sahin’s account, saying in the earliest months of 2020, he was focused on maintaining the company’s operations in China. But by late February, he said, he’d determined Pfizer needed to work on a treatment and a vaccine.
“What is the best approach?” Bourla said he asked his team.
Kathrin Jansen, head of Pfizer’s vaccine research and development, said they assessed all existing technologies, including protein-based vaccines and vaccines using viral vectors.
“They all have too few pros and too many cons,” she said.
But messenger RNA was a risk; it had never been used before as an approved vaccine or drug.
“I wrestled a little bit with the decision,” Bourla said. But after another meeting with the team, “they convinced me.”
That’s when Sahin called a second time. The outbreak, by that point, was already in New York, he said. Reaching Jansen, he described the work that BioNTech already had underway, and asked if Pfizer would like to work together.
“And I said: absolutely,” Jansen remembered. “Let’s talk about this.”
At Moderna, it was never a question that messenger RNA would be the way forward; that was the technology around which the company was founded in 2010. But that didn’t mean questions didn’t exist.
“Even going into March, there were voices that said vaccines were false hope,” recalled Dr. Stephen Hoge, Moderna’s president. “It did feel for a period of time that we needed to defend even the idea of trying.”
“When we were thinking about how do we get into Phase 1, what does it look like to prepare for a pandemic, the eyes of the world felt as though they were looking at Moderna as this biotech ... ‘what are they trying to do?’” said Hamilton Bennett, Moderna’s senior director of vaccine access and partnerships.
“It was only when we transitioned in that March notification from the WHO that this was a global pandemic, it’s an emergency, that I think people started to realize that what we’re doing isn’t playing in a sandbox trying to demonstrate our technology,” Bennett said. “We’re developing a vaccine that’s going to stop the pandemic.”
The companies succeeded, in what became one of the greatest medical races in history. Here, they recall how it happened.
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A Race Against Covid: How Moderna And Pfizer-BioNTech Developed Vaccines In Record Time
It is a shame that the Reporter only talks about "Pfizer", when the crucial technology/Knowhow came from Biontech and it was a team-effort.
The devils work
@@sl4074 BS, you should brush-up your high school biology.
They don’t only mention Pfizer… watch the entire video. BioNtech is mentioned right after the Pfizer segment.
@@sl4074 I guess the devil actually loves humanity since it’s keeping so many ppl, including myself safe and healthy! 🤪😉😋
@@EndeavorsDnB that is exactly my point Biontech was "mentioned" when in fact they have partnered with Pfizer and so one should talk about "Pfizer-Biontech" or "Biontech-Pfizer" as they launched the vaccine together.
I love Ugur's and Özlem's work ethic.
Alex seek help.
I prefer Stéphane Bancel
ahh, when moderna stock was $28 instead of $400
No worries.. the recent "withheld from american news mainstream" Japan halt.. brings them into suspect through out the rest of the world hearing about it.
I got in early
Yeah it had recorded losses year on year since its formation and now has two Billionaire executives since signing a liability free contract . It's far from a good thing.
@@SeeTheWholeTruth why us Japan halting this vaccine
@@lamondhaughton1598 It is in the news, not "withheld" - there is a batch that may be polluted.
The REAL hero is the German Company BioNTech!
All three companies are heroes. And astra zence and j and j
Yes, 500 of their scientist were involved, thousands man hours....?
I dont even know The Type of vaccine i should Take i have appointment on tuesday am even confuse
No heroes in big pharma. Only profit mongers. Follow the decades long patent and money trail of cv19 and the vax. Nothing novel. Nothing unplanned. ua-cam.com/video/ihjNDf32_Ac/v-deo.html
@@gmw3083 Pfizer.JJ, maderna and others can’t come up with the cure for CANCER in “record time”....
You’re the only one that got it right on these replies to this post..
Dr Ugur Sahim "We didn't start the company to become rich. We really start the company to make a difference."
A big Salute to that and the world thank you and your wonderful team!
😂😂😂😂😂😂😂
People: Hurry up with the vaccine, fast!
The same people: Now that you made the vaccine, I don't want it because you made it too fast.
I regret ever having the vaccine, my heart and lungs are inflammed, shortness of breath, heartpain...
@@kadd14 cap
@@kadd14 I really hope your OK my dad died of a heart attack after the vaccine but none of this ever gets mentioned by the media
@@buzzkillington3354 ur dad could die for a lot of reasons from heart attack ...but whatever ... U can't change a covidiots mind
@@kadd14 Follow the decades long patent and money trail of cv19 and the vax. Nothing novel. Nothing unplanned. ua-cam.com/video/ihjNDf32_Ac/v-deo.html
I like how they say polite “Possibility to help” instead of rough “Possibility to multiple income”
So what? They help and make money
@@peres9559 And, if it doesn't help, there is also no money.
@@pizzablender But if it is actively pushed and mandated its very hard not to make money!
@@dendradwar9464 if the virus spreads and economies have to close then no one makes money
I rather call that ”The beauty of capitalism”. There is a beauty in that capitalism drives innovation while saving lives.
It's called not testing your products.
Via having zero safety concerns anything is possible.
If we can get a vaccine so fast why cant we find a cure for cancer?????
They are trying to modify the mRNA vaccine to attack cancer cells. Not sure if anything will come out of it but I sure hope so!
Cancer isn’t COVID.
@@theroman2130 did I say that it is??
A bit of a silly question buddy cancer is a whole different ball game
@@Whyoakdbi I wasn’t responding to you. I was responding to the original comment.
It was really the courage to go after this very early even thought it was completely unclear whether the work would be relevant.
"This is a sign how this pandemic is gonna end"
Delta: hold that thought
Yawa
Vaccines are also very effective against severe disease with Delta. In the Netherlands: 95% lower chance of hospitalization for the vaccinated group.
I think this is a great documentary, very informative. Just wondering why CNBC felt it necessary to do an Apple product placement ad?
Johnson and Johnson: Am I a joke to you?
JJ used to be targeted at babies bottoms ( baby powder and baby shampoo)..NOW.....?
well.... yeah?
42:14
It was the first sign the pandemic is going to end
Anti-vaxxer: "Hold my corona beer"
With the leaky "vaccines"... it's never going to end. The vaccinated will envy the unvaccinated.
All you had to do was ask for a beer you didn’t have to be weird and stand in the corner
@@chaosengine3772 the vaccinated will envy the unvaccinated? What exactly are you smoking? Although the vaccine only provides a low protection, it is still better than no protection, and the side effects aren't really that big of a deal as what anti vaxxers made it out to be anyways. People all around me have been vaccinated, and they can't be any better than that.
@@mischievousalien8873 The vaccines protect 95% against hospitalization and possibly more against death. How is that "low"?
@@pizzablender Is it still 95% against delta though? Last I heard, it's way lower than that, regardless it is still better than no vaccination
Come up with a vaccine for Dengue Fever at the speed of science and you will make me a believer.
It's all about the money, from it's beginning, to the end...
At least 99.9 percent ...the rest actually want to help people..lol
great video! very informative about what was going on behind the scenes. the whole world should be grateful to all the people that dedicated themselves to solving this gargantuan problem and also to the people at cnbc and other news outlets who helped to keep us informed about the progress and continue to do so even to this day. great job everyone! 😊
Wow great video really..........wow
Propaganda its called
@@sl4074 I'm surprised you could spell propaganda, I guess you watch enough of it, right?
@@dodgemF1 why so friendly?
The real question is -have been they working to develop a vaccin since the 2002-2003 corona virus outbreak or they have it already.
who played the largest criminal fine in history??? look that up
Hamilton Bennet looks and sounds like Rachel McAdams.
Moderna staff are all smiling as their stock is almost at $500 now.. must have made these people very very rich
Sure. That doesn't mean the vaccine isn't effective, because it is.
''If you Tolerate this then your Childeren will be next" 1998 Manic Street Preachers
How did they do it? They probably had this ready before the public ever heard of Covid. And there were exceptions made for every normal safeguard.
These guys have no choice. The opportunity landed on their lap on something they're prepared for. Success = preparation and opportunity.
To save you 55 min. They did it by funding! Yay cause it proves that all those donations given for research barely do anything until it’s real direct funding that does it
Many scientists grind out a life using those donations. If you have the ability to support similar causes by donations, it’s going to help the silent heroes everywhere.
Lab scientists of these companies are the unsung heroes.
absolutely
Nice 1 hour ad. Why push mRNA and do not to tell anything about J&J and other vaccines?
Those vaccines aren’t very exciting or as effective
@@MikeJones-kb9ub AZ is actually better now . So are sputnik
@@thewolfofswingthat2035 CDC data published 3 days ago shows moderna 95% effective against hospitalization due to delta, Pfizer 80%, Jnj 60%. It didn’t list the others because they’re not widespread in the US. Do you have data on those?
@@MikeJones-kb9ub I read in my country that AZ death after 2 doses is the lowest. Probably not interesting enough for you but just providing context of what i said.
But I'm still player one though. Not in service .
Billions and billions let's talk
The beauty of capitalism! 🖤
Moderna vaccine recipient thank you for all of your efforts and Pfizer too. You have saved the world
Please dude hold your thought, as the saying goes don't praise the morning before its over. "Saved the world" - are you unaware of the people dieing everyday from this chemical they're forcing upon the human race? If not, you might do some research before stating such BS in future.
@@CompelledFungus The benefits outweigh the risks. Vaccination is the way to go, sure there will be some risks involved, but its all worthwhile
Thank you @@mischievousalien8873for making the healthy beautiful life I've lost worth it. Total closure.
Show us your pay stubs for this lying statement. Who was it? Sorros, Gates, Bezos?
Your last comment about rethinking cloned animals for food production. I don't think that's a thing. They do artificial insemination, may use a lot of sperm from one male to inseminate many females, but there's limits to one male's sperm production so many males have to be used. There's a lot of monoculture using a single species, also using individuals that are related closely to each other, but not animal cloning on a large scale.
Shame on CNBC for not pointing out that Moderna and Biontec’s work hinges upon the research done by a Hungarian American researcher when the medical science field gave up on MRNA. Biontec literally hired her. She believed in MRNA even when U Penn demoted her for a lack of grants for her work. She made personal sacrifices that benefitted the world. Shame on CNBC.
Shame on her for not crediting Dr. Robert Malone for the original idea and work.
Inspiring. Amazing. Informative. What a great video. Thank you for creating and posting this. These are the people who deserve Nobel Peace Prizes. What courageous actions.
You really have no clue
At least first 15 minutes of that video it's all about money and stocks....
It’s CNBC, a business-oriented channel
Welcome to late stage capitalism. Money is the reason for any "humanity". Not actual humans.
@@ashleekat3 You're on CNBC. If this was on the Food Network you wouldn't say "shut up about food already and talk about the peeeople."
Its a business channel. Plus, some of these companies have raised billions from the stock market through stock sales, which helped them raise capital for big clinical trials and ramping up manufacturing, which means the stock market has helped as well in getting these vaccines out in a record time.
@@amols101 "for big clinical trials" can you tell us more about big clinical trials? Do you ever know stats and numbers?.............. Business, sales, stocks - everyhing is nice, but until that vax became mandatory....
Adding a comment here to get the comment count to 667.
I do that too.
I remember the excitement of these news stories breaking in late 2020. Unfortunately now in late 2021, we are facing into 3rd and 4th doses which is not what we had hoped for. The vaccine’s effectiveness in limiting transmission has also been disappointing.
With hindsight, the vaccines are saving millions of live. Didn't block transmission, but that was never the intent. They still reduce hospitalizations and deaths.
Because they didn’t test for transmission before releasing it
What would we do without these folks; they giving up their precious hours 🤧; unselfishly giving up precious, personal lives. 💙
Making billions and billions of dollars...
@@josefdenis3799 just throwing numbers like an idiot ...
precious hours exchanged for 3 billion dollars of net worth. Anyone who studied Biotechnology within the RNA-field would do the same
None of them are giving up hours.. they are all getting paid big bucks for each hour
@lakeshop your comment is nonsensical. It seems you fail to comprehend what exactly OP said, and what me response was to.
Thank you for coming out of left field with a comment that has nothing to do with anything being stated here.
Additonally, Not sure if you're calling someone here an "antivaxxer", but I find only communists use that terminology. Get out of here with your polarized politisism.
Also, anything that comes to the people is not free, the cost is merely reallocated. Companies manufacturing "vaccines" are making plenty of money because the government buys each shot with your tax dollars, instead of making you pay for it directly.
Nothing us ever 'free'
Thank you to the companies, doctors, scientists, geneticists, and frontline workers that made this possible. A true achievement in human healthcare and logistics.
I agree with your comment
Lmao what a sheep
@@Adam-tw8yd lol says a laker fan
@@iceman18211 hows the vaccine doing for u lol
@@wenzyybeats9223 Preety good got all three doses. Nothing different from the regular flu shot.
THE TWO LEAD FDA VACCINE REVIEWERS ARE QUITTING
Gee, I wonder why?
Pls make a video on different covid vaccines(Name wise specific) explaining them all including indian vaccines such as zycovd
cannot make anything that does not support the WHO ideology. if it is against WHO , then the video gets deleted. i already tried and got warning about it.
ZyCov-D is an interesting one. I suppose they can all be explained, but the effectiveness and safety must always be tested no matter how great the theory behind it.
@@miimbiits what do you mean by WHO ideology
Vaccine explanation is promoted by WHO to grow awareness about them
Well done CNBC! It so great to hear from the people that worked so hard to bring a vaccine to us in record time!
🤣🤣🤣
You are so low info
He came from under a rock 🪨
an hour long video :O
:O
Don't think anti-vaxxers have the attention capacity to watch a hour long documentary
agree way to long. watched at 3 x
Just because we want more then 10 months of data, does not mean we are anti vaxxers.
Helll nah.. your people made the virus and now cashing in on a fake vax .. that doesn’t help
Sheep do want some grass while you watch it
I'm an anti vaxxer and I watched and listened
This is a Story Humans Best Side
I agree !
This is how humanity can survive disasters... by working for the greater good (especially on the Oxford/AZ side of things, they are non-commercial).
#pureblood4life, because the salt must flow!
"You got the jab?"
*preps metal slab
Tonix Phamaceutical ! TNXP ! A2PUSY
Thanks for the vaccines.
Imagine a world where there was a 99.8% chance you would not poop your pants. But you're forced to wear diapers just in case. Not for you, but for others.
Totally the exact same scenario, great observation Plato
covid nurse here - all us nurses knew immediately how bad this would be just from watching china -if only the phblic had more knowledge of public health and infection control they wouldve known too just follow the science
@mmiller4255 they won't ever know the true death rate because it's all clouded by lies. Most hospitals report their deaths as covid ones regardless of the prognosis so they can fill their pockets.
are you still alive? Just checking. 🤔
But it wasn’t as bad we didn’t have ppl collapsing in the streets suddenly. And they now say covid was likely in USA in November 2019
PERTAMAX
Just throw a little this little that in dere
‘94.5 & 95.5 percent effective’ yeah in another dimension maybe
Like maybe length or width? Which dimension. Maybe height?
In preventing severe illness and death? Did you miss that dimension?
@@amols101 FLU
Against hospitalization for the Delta variant, yes. Those are the current numbers.
@@istvandjumber6474 I am sorry about your friend, but what about "not 100% effective" doesn't make sense to you? 94% does not mean complete immunity.
I love how the french guy says "mRna"
really remarkable
Great day for science. Great day for humanity.
ZERO LIABILITY.
Zero liability for vaccine manufacturers isn’t new. Been that way for a while.
If we few hundred ppl suing these companies when millions benefit, no one will make future vaccines. Get a grip.
Singapore teen receives S$225,000 compensation from the Singapore government after getting cardiac arrest from the pfizer jab. Are there any compensation program in your country? why are pharmaceutical companies exempt from lawsuits?
How about sputnik, sinovac and that of Cuba. ... they don't appear to have media exposure...😎
$$$$$$$ thats how it was developed so fast..
this documentary is all about businesses and how well they make it to the market. :D
美国莫德纳制造了新冠
hmmmmmm
… they appear to be doing a victory lap. Sorry we can’t watch but large groups can’t gather as we have a pandemic still going on .. but really so excited how much money this made you all .. I gotta go my house is being foreclosed today. But your work ethic in the office by 8:30 In a room on the phone and thinking about it all the time., wow that’s commitment. I found out i was not essential so you billions.. others homeless .., makes sense .. good for you guys.
and the thought of not being the first to announce it.. oh the horror.
Great documentary. .. Keep it up !! 👍🏾👍🏼
PROPAGANDA
The real heroes.
They only care about money
o7 to those sacrificing their own life for Coronavirus Pandemic and also those who risk their life for eliminating Coronavirus for life return to normality and per Dr Fauci in recent CNN interview said that United States to return to ‘degrees’ of normalcy in Spring of 2012 (2022) and my home country Saudi Arabia is returning to normalcy by Summer of 2012 (2022)
@@doomi4055 you are brainwashed. Corona virus is all a scam man wake up
@@sl4074 Says who? That Mercola or so who is peddling his fake "cures"?
@@pizzablender alot of respected INDIPENDENT doctors thats not corrupt
Ahaa yes, I see am late for the comments section,
Gather here comrades
👇
Amazing stuff guys! Pandemic stopped in Israel after 4th shot. Zero side effects. We should put this mRNA tech into our drinking water too.
What about long term side effects?
are you still alive? Just checking. 🤔
We need universal healthcare where ALL medicine is free and 0 profit, then we will see where these good hearts truly are in the world.
so who is gonna pay these guys to do the work for free? You want free housing to end homelessness too??? same argument. lmfao
@@cutehumor I don't want MAGA anti-vaxxers to get free healthcare. I totally agree with you.
These guys and their teams are all the real heroes and deserve more praise.
đội cái rế nồi lên đầu là đỉnh rồi
Business is doing great
Intellectweb
Did someone expect to hear something else from direct employees, co-founders, CEO, chief and head of research about their products?..... With in the first sentence in the description "and will reap billions of dollars in sales of their vaccines this year alone." What did you think they could tell you?.....
Which vaccine according to the data is better against delta variant, sputnik V, moderna, Chinese vaccines??? Which country do best in beating coronavirus??? Could you tell us or your videos are doing only propaganda ????
It's almost like they planned it years in advance...🤔 Too bad they couldn't finish it until their fanboy joey b was in charge...
Firing squad needs to be ready for these demons. It was so obvious it was dangerous from the get go. That's why I didn't get involved.
I’m usually a bit cynical 🤨, but these scientists with their decisive actions saved a lot of lives
14:59 The Ab is oriented the wrong way.
Amazing story of teamwork, private enterprise, and biological innovation that we were able to deliver a safe and effective vaccine in less than 1 year - truly admirable
Wish u were here rn cuz I could show u how "effective" the vaccine is
😅🤣😅😆😂🤣😅
@@drewywgx924 3 billion jabs given, people still doubt it lmao
@@thetaomega7816 if it doesn't keep you from getting it, or spreading it. What's the point.
@@drewywgx924 It does keep you from getting it, even with just partial vaccination... have you read ANY of the peer-reviewed data on these issues? Or just InfoWars?
no person ,who is informed, trusts these companies or their posions
There is a world beyond USA which had also developed vaccine in record time
Which countries Mr Gupta and are they effective !
@@anaveragejoe6710 lol that is the most typical arrogant American thing I have read for awhile.. The UK are mostly vaccinated with something not developed in the US and although it's too early to judge yet it looks like it will have a longer duration between the booster shot duration of the American vaccines....which is currently looking like a jab every 8 months lol
@@anaveragejoe6710 India, UK, China, even Iran. I think it is not a hard virus to create a vaccine for.
Disaster
Lots of people complain that these companies earns a lot of money.
Have you often do your job for free for many months?
If these people don't earn money the will be no vaccines or something else next time.
It really is fascinating how they expect private companies to... not ask for compensation for their vaccines?
Problem with that is, the pay is excessive..they’re really only earning about half. The rest is simply gouging every one. Healthcare industry is a game ..
Really, it is too early to show happiness, as we don't know what is the side effect after taking this new biontech vaccines on us after years.
blah blah blah, still would never take this sh^t
They air this nonsense.. a day after hiding this fact from the Usa news.. "Japan suspends 1.6 million doses of Moderna shot"
Dinosaur.
Good. Your account won't be active to make more comments.
. . . Same - I hear dewormer paste for sheep is the way to go. “They” want you to take the FDA approved vaccine with proven safety and efficacy, but the people who aren’t actually virologists or vaccine experts know that off label stuff that isn’t proven and has horrific side effects is the real solution.
@@BoomerPlusUltra FDA approved, now thats a joke.
someone forgot sputnik beats pfizer-BioNtech and moderna
I’m sorry, did they say they only infected 80 some people out of 30,000?
I was in detp when I came across ☝️☝️👆, now they cleared all.
So...the narcs and capitalists saved us all!
Keep kids koi
It's "science". You're not allowed to question it anymore, just believe in it. You know, like religion and stuff...
But science is about questioning...
@@seasong7655 Except if you dare too in this case you will be banned and shunned off the internet. LMAO. #TrustTheScience
@@ashleysigurdson6982 Yeah but for good reason
Right brainwashed we are
@@seasong7655 Rules for thee, but not for me. I mean if its legit then let them analyse it themselves, unless.. ¯\_(ツ)_/¯
.
One Answer: Donald Trump
and His Mission Warp Speed,developed these vaccines.
very disappointed with this interview, hoped to see more technical "how its made" vaccine content.
And the ingredients in this vax
If you haven’t seen, there’s an excellent article titled “Reverse Engineering the source code of the BioNTech/Pfizer SARS-CoV-2 Vaccine” by Bert Hubert (oddly, a software developer-but with background in writing on these topics and well-checked by experts in the field). You can go down a few rabbit holes from the linked articles; there’s a good one on the supply chain for actually producing these vaccines, and another on the lipids that allow the vaccine to actually be delivered into cells.
@@AmbientMorality what about this ua-cam.com/video/ihjNDf32_Ac/v-deo.html
@@jameskptan I don't really care to listen to an hour of misinformation. What's your point?
@@jameskptan The Bert Hubert article is great, actually.
a race again humanity...
They had a deal with the devil 😈
Amazing clip.
i n t e l l e c t w e b you are the best term in the world thanks for the payout I really appreciate you
mRNA
🌎 🇺🇸 🇨🇦Hats off to Moderna & Pfizer- BioNTech for becoming saviours of humanity 🌍 🇬🇧 🇩🇪 ... The top scientists had a lot to prove before actually being taken seriously such as: efficacy and effectiveness of mRNA vaccine and expedient approval process for such vaccine that otherwise could take several several years. Satshriakal, pranam, natmastakam and sincere best wishes to Moderna& Pfizer- BioNTech and to all concerned 🌏🎅 ✝ ☸ ⛩ ☯ ☪ 🕉 ✡🌸🌸🍁🏵🏰🗻🎄🏞🦅🌲💐💐🙏🙏🙏🙏