Why Evolution Hasn't Gotten Rid of Allergies
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- Опубліковано 1 чер 2024
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Patreon: / realscience
Twitter: / stephaniesamma
Instagram: / stephaniesammann
Credits:
Narrator/Writer: Stephanie Sammann
Editor: Dylan Hennessy (www.behance.net/dylanhennessy1)
Illustrator/Animator: Kirtan Patel (kpatart.com/illustrations)
Animator: Mike Ridolfi (www.moboxgraphics.com/)
Sound: Graham Haerther (haerther.net)
Thumbnail: Simon Buckmaster ( / forgottentowel )
Producer: Brian McManus ( / realengineering )
Imagery courtesy of Getty Images
Music:
special by anbr
still-life by anbr
pieces---instrumental-version by oroka
aftershocks by ardie-son
fury by ardie-son
waiting by brianna-tam
growth by brianna-tam
morning-sunbeams by yehezkel-raz
References:
[1] pubmed.ncbi.nlm.nih.gov/26943...
[2] health.howstuffworks.com/dise...
[3] www.who.int/news-room/fact-sh...
[4] www.ncbi.nlm.nih.gov/pmc/arti...
[5] pubmed.ncbi.nlm.nih.gov/26513...
[6] www.jstor.org/stable/2830331
[7] naturemed.org/how-toxins-caus....
[8] www.sciencedirect.com/science...
[9]pubmed.ncbi.nlm.nih.gov/24210...
[10] www.cell.com/current-biology/... - Наука та технологія
Remember that for every negative comment you get there was probably 100s of us who watched, enjoyed and simply didn't comment. The mean ones are always the loudest. All the best!
I try to remind myself of that! at least I can now laugh at the mean ones
Negative comments?
I have never seen them.
Is it okay if I ask you what they criticize.
I just want to know what their negativity is about.
@@Handsome_Thanos I was referring to her sponsor segment at the end of the video where she shows some examples
It's definitely true!
@@realscience Love your videos! Actually have recommended to many of my friends ❤️
I don't think mice get anywhere near enough credit for what we put them through...
Well, they've build them several statues... But yeah.
If you had read the hitchhikers guide of the galaxy you would know mice are actually controlling the earth. Them being our guinea pig is just a trick to fool us
Rest In Peace to all the ones that didn’t make it
dunno if its only Russia that has a statue honored for all the laboratory mice that were experimented on
There actually generated, Mice 🐁 for the credit, unfortunately others are not credited for destroying plagues of them, so please try to understand the human body is a complex system, constructed for repair.
It's a glitch, I'm waiting for the patches updates so I can eat shrimps again
Gene-Editing
Your mom and dad gave you a bad version yo.
You can't it's unfixable unless to reborn/respawn. It sucks.
@@128Cores
Gene therapy works
Well, with CRISPR, you might be able to in the near future. That is if anti-science people afraid every advancement doesn't prevent it.
I was quite surprised that people comment negatively ever about this channel. So much research is clearly done and lots of effort is put into staying relevant and not biased when delivering the information. Just wanted to say people should be thankful that this level of quality is available for free. Also, I always have found the narration to be compelling in terms of calm delivery and tone. Stay awesome!!
thanks! haters gonna hate
every channel has got em right, learn and focus on the good ones !
After all, the weirdest it can get is, being allergic to allergy medication.
Me too 😳😝
Also, an alergy to the water and _sun_
Yeah it's strange I can't take a certain antihistamine (allergy med) because I throw up
@@rac1equalsbestgame853 I think those allergies work differently, because there are no proteins for the IgE to attach to. So calling them allergies might be a misleading in the first place.
@@rac1equalsbestgame853 You cant be allergic to water (H20) you are 70% water.
I really liked the way this explanation was: showing the "bad guy" inside of your body is in fact the good guy
Maybe I don't want to be the bad guy anymore.
no no no I'm tired of dealing with pollen from flowers because some moron cells thought It's helpful, STOP PRODUCING THE ITCHY EYE AND SNEEZY JUICE EVERY SPRING IDOIT CELLS.
More like the bad guy in your body gives you some benefits
@@Shuker8964 yeah like not overthrowing everything with autoimmnune diseases
Nah, it is still a toxic relationship xD
I had a scratch test done when I was 5 back in the '60's and was allergic to over 200 things. Through my teen years, my sinuses would close completely during certain times of the year with no meds available. Then in adulthood, the allergies lessened to just a mild annoyance. Now past 60 they have come back with a vengeance but at least we have meds for it because without the meds the allergies are overwhelming. I enjoyed the video.
God I couldn’t imagine not having meds available. I’m in my 20’s and as a child I suffered horribly from allergies. Didn’t help living in an old farm house. My well meaning mother didn’t want me taking any pills so I had to always tough it out with strong cups of coffee and steam.
As a person who suffers from allergies from sources such as seasonal, pets, dust and mold, I appreciate a video that delves deep into this topic. It's good to know that researchers are working on this. Glad to get here via Tom Scott
Nearly everyone has those allergies lol, and everyone is allergic to dust
@@VantageX what? Im defineatly NOT allergic to dust and most people arent (though it surely isnt rare either), my body doesnt have allergic reaction to dust.
And WHAT? "Nearly everyone has thoose allergies"?? Majority defineatly have one of thoose allergies, but "nearly everyone" isnt allergic to PETS (sure, many people are allergic to some pet type).
Mold allergy? Ok, that is something nearly everyone(or just everyone? I dont know) has.
Nearly everyone? That's quite an exaggeration - most people I know look at me like I have 3 heads when I sneeze uncontrollably
@@colleenmarin8907 yep, and then he claimed "everyone is allergic to dust", without even "nearly everyone"
@@VantageX Wow, it's rare for someone to be as completely wrong as you are.
Finally, an explanation to my BLOODY SNIFFLES
I realize you're not from the US but bloody sniffles sound terrifying
@@Saltiren lol
I learned so much in a very short amount of time. I probably wont be able to remember details like specific names of the parasites or the cells, but I will now forever know how allergies work. Thank you.
2:01 What are allergies?
4:53 The Worm theory
7:57 The Toxin theory
12:59 Final thoughts
Passenger of Shit - Staple Tapeworms On My Penis
Thank you
If you click the description and scroll down, you can see the chapters there. Maybe they have been added in later than this comment but now they are there.
"...and my favorite, almost-but-not-quite sneezing."
It's a mood, lol.
Good job bringing this topic to light. I've read enough BS on Facebook regarding allergies & the crazier treatments prescribed there. This video needs to go viral for everyone to get the basics.
Also, amazing revision on how it's the histamines that get released post-allergies. The animation really cemented it for me.
Those crazy ppl tend to have numerous followers. And to some ppl with fallacious reasoning, more followers = more credible.
nowadays everyone is an expert in *insert field of science*
That’s your problem there. You are on Facebook
@@jimmymememe5917 Yeah... a GOOGLE expert!!! But the problem with all the algorithms that feed you stuff is that they feed you the stuff that have already liked!!! Ya gotta go for the opposite viewpoint(s) too in order to find what you really want to see. I always do that. If you only like the stuff that you are already biased towards... you won't expand your mind or your knowledge very much.
@Rohit Pant Get your REAL info off of FB! It is a good place to engage in discussion but not so much for any REAL info! I subscribe to several groups that are there for SCIENCE and not bullshit. There is good stuff on FB but you really have to sift through the crap too. THAT can get very tiring.
This and Real Engineering's content is always amazing and insightful. There are only a few channels that captivate me this much. Props to you and Brian!
I could recommend a few more if you like.
@@lonestarr1490 I'd appreciate the recommendations too
@@joshuaosei5628 Ok, let's see.
I'll start with the more popular ones. I realize you might already know them but it would be 'irresponsible' to leave them out (if you don't know one of these, check it out instantly!). Those are:
_Kurzgesagt - In a Nutshell_
_Veritasium_
_Vsauce_
_It's Okay To Be Smart_
_LEMMiNO_
_Tom Scott_
_CGP Grey_
These channels cover a pretty broad range of topics. I have some more specific ones which I like very much. First, of course, the PBS channels, like
_PBS Eons_ about the geologic and evolutionary history of the Earth
_PBS Space Time_ about space and physics (pretty advanced stuff)
_PBS Terra_
Since I'm quite fond of astrophysics and alike, I got some more channels about that:
_Astrum_
_Isaac Arthur_ about futurism and what ideas from science fiction might be realistic in one way or another
_Anton Petrov_ more like space news, new video almost every day
_SEA_ (great visuals!)
And some more about physics, biology and alike:
_minutephysics_
_MinuteEarth_
_DoS - Domain of Science_
_Bizarre Beasts_
_Up and Atom_ (recommended for kids because of very clear explanations and demonstrations, same goes for Vsauce)
And about technology and engineering:
_Mustard_ (great visuals!)
_Verge Science_
_FutureNow_
_Undecided with Matt Ferrell_
_B1M_ the definitive channel for construction
_Tomorrow's Build_ from the same dude, but focused on future tech in construction
Miscellaneous:
_3Blue1Brown_ the single best channel about math
_Wendover Productions_ about logistics and how certain complex systems work, like the aviation industry (his other channel _Half as Interesting_ is hilarious)
_Answer in Progress_ ludicrously sympathetic team of students fooling around to try and figure things out
_Atlas Pro_ geography, but pretty interesting
_Risen Africa_ geography, politics, and future of Africa
_Economics Explained_ (it's in the name)
_Rare Earth_ traveling the world finding stories you'll probably never hear of anywhere else
_Cogito_ about cultures
_NativLang_ about linguistics
(Yes, I have various interests)
@@lonestarr1490 Whilst I did know most of these, a few I haven't heard of, so I'll be checking them out. Thanks :)
Why are people who deny evolution commenting on science videos? They shouldn't be using the internet in the first place. If you deny evolution, and deny science, you shouldn't get to benefit from it. Ignore the negativity, and please keep up the great content!
Amen brother
Denying evolution is not denying science. Evolution cannot be proven using the scientific method
@@tmth.stevensIt literally has been with a vast amount of evidence that would stack so high if in non-digital form it would probably reach the moon.
@@tmth.stevensI absolutely loved your video where you play the organ, I subscribed. Please share more!!!
I'm a biologist with a phd and your films are hands down the best documentary series on the internet! Mind blown with every episode - this is some hardcore stuff! Keep it going please 😁
hay fever takes all the joy out of summer for me, the times i spend as a kid chilling outside on the lawn or at bbq with my family is just not fun anymore, its a real bummer, but it makes me enjoy the winter all the more, so thats nice atleast ^^
As a biology student, i really appreciate the work and time you put in these videos. They are amazing and i always learn something new or get more info about something i heard in class. Watching educational videos helps me remember information better than reading blocks of text. Thank you!!
me too do you have any recommendations for other channels that are similar to this one?
I'm not supposed to just say, "I'm here from Tom Scott", so I'll add the video is pretty dang good. Subscribed.
Haven’t finished the video yet but I second that.
What video did he recommend this channel? I just got here through sharks.
Wow, the narrator has such a soothing voice, with great clarity and enunciation. Coupled with in depth research and excellent presentation too. I watched the entire video and was delighted to hear new information on the topic of allergies. Usually I don't leave comments, but seeing the negative feedback at the end pushed me to write this. I have a terrible, grating voice that many people despise, and so I was personally offended to see them hating on someone who sounds perfectly normal. Ignore them, keep making great videos.
agreed her voice is a comfortable voice to listen to and also gives really interesting facts about bio and i love it sm
I hate my voice too. I wish people would see that a voice is a physical trait, and criticizing it is no different than criticizing someone's appearance.
This was another great video. You are seriously the best UA-camr in my opinion. When one your videos comes out, I know I'm about to get an in depth look at an interesting topic. Keep up the great work.
me too, I eagerly wait for your videos.
Agree on everything you said!👌
I feel the same way, then I often explain topics I learned from the videos to my friends or family and they are often intrigued as well. The topics are often interesting and in-depth, which I highly enjoy.
she's amazing. just discovered this channel recently and it's been nothing short of 🔥🔥🔥🔥🔥🔥🔥
@@pjhoody then check out Real Engineering channel too.
Dude you are so great at explaining those concepts. I feel much satisfaction after learning that explanation
“It’s MA’AM”
@@TKUA11 dude is a gender neutral term
Dude actually means: man of fashion. A man that cares alot about his physical image. It used to be a word for gay or metrosexual guys but thats because those guys tend to voice/show their care for fashion while other guys dont want to be assosiated with women and/or gay and therefore look flatout messy/uncaring.
Anyways: while not meaning what most people think it means, its from histories perspective an inherently gendered word.
Doesnt however means it has to stay that way. We give meaning to words and without us they are meaningless nor even existent. One thing people can do is own the word and give it their own meaning.
@@Psilocybismwhat a word _means_ doesn't really matter, only the way people use it
@@DustyyBoi What a word means has a direct influence on how people use it though.
This is so weird... Both of my parents are from central Mexico, like several hundred miles away from any ocean. Their family has been at that same town for generations now. My great grandma has pictures dating back to the early 1900s of her family in that town. There is even this picture from my now deceased grandfather, of his grandad that looked exactly like him. He claimed that his grandfather and his family had been living there since the 1800s.
For whatever reason, my sister was born with an allergy to fish. Even the smell of fish, especially when being grilled or deep fried is enough to kickstart her allergies. The first time we found out about her allergies she almost died. Her throat and face swelled up and needed hospitalization. This was after she put a piece of fish in her mouth, didn't even swallow it as her reactions started kicking in immediately from touching and tasting it. So I have no freaking clue how she developed that allergy, based on this. Our family never really ate fish since they lived hundreds of miles from any ocean and several miles from any large body of water or river and my family had been living isolated from the ocean for hundreds of years. No one in my family has this allergic reaction to fish, actually nobody in either of my families has any allergic reactions other than my sister. Sister is also allergic to pollen... Also doesn't make sense since the town where my parents and their family is from doesn't really have flowers, its all like a desert.
Very strange. Maybe evolution is actually working the other way around.. maybe we started with deep allergic reactions but then when we needed to eat fish or to walk around the flowers we had been selected to have lesser responses and perfectioned the binds against venom
It could be a mutation her DNA or maybe your parents had recessive genes carrying the allergies
It’s probably just a molecularly similar protein to one that she could have been exposed to (unknowingly) as a baby, like the video goes into? Just my thoughts
I'm a super nerd, and I like to find flaws in these kind of videos... but you totally did a fantastic job. I wouldn't say that if I didn't mean it. Keep making more! You're doing great!!!
Passenger of Sh*t - Staple Tapeworms On My P*nis
Lol weirdo
🤓
Wild😂
which flaws?
You are one of the few on UA-cam who still teaches me things I didn't already know :) Thank you so much!
I've been on antihistamines for the last sixteen years - no idea what I'm allergic to, but its literally everywhere it seems xD ... So I'm especially happy you decided to shine your light onto this particular topic.
Those youtube comments at the end were heartbreaking, your voice is great and your videos are superb! Keep making awesome!
It’s a fair critique to make, although could have been communicated more respectfully
of course they were all anti-evolution morons
Thank you for this, ignore the ones that ignore science. You dedicated a highly applaudable amount of time to research, write, animate, and produce this video. All because you wanted too and felt that others would be curious about the same thing, I definitely was. So thanks for devoting that time and please keep it up so all of us can learn more!
As one who experiences hay fever, this was a refreshing new perspective on why it happens and why, while frustrating, it's part of a bigger picture and more important system. Thank You!
Keep banging away! Your videos, and the information within, make a difference. Learning dry topics can be boring but you make it interesting. That takes skill. Keep at it. I'm a fan!
She’s too nerdy to keep banging away
An idea for an insane biology videos, animals of the deep sea, it would bring me very happy to see you cover these sorts of animals. If you read this, thank you for your time.
good idea!
@@realscience thank you so much, it means a lot to me that you would take my idea into consideration. You are my favorite science channel on this platform, keep up the fantastic work.
I also like deep sea creatures
After I know how difficult it is to learn the immune system and how much a medic student has to study to remember all the details, I have a lot of respect for you being able to condense it down into a short 15 min video while not just simply skimming over important facts. Well done video!
The only thing left for me to ask: Are there any studies out there that ask why people who have allergies often tend to get even more, a lot of the times not even connected or crossed ones, but completely random new ones. E.g. I started with a Penicillin allergy, added a peanut allergy on top of that and now I am reacting to almost any kind of nuts and certain drugs like Amoxicillin and Penicillin.
This is a great question and I am no biologist this is my speculation as someone also with compounding non related allergies; could it be related to the fact that allergic reactions increase in severity after each exposure, therefore priming the immune system to be overly sensitive to the allergens but are so reactive that they assume any small potential allergen or one molecularly similar in structure to be of high risk, therefore triggering the response? Would love to learn more from academics on it!
@@smears6039 I would disagree with that hypothesis just on my own personal experience. While I have multiple allergies, I didn't get any new ones in the past few years. Secondly, for your guess to hold true, I should have developed a dust or dust mites allergy already or even sooner than my more outlandish ones, as those are allergens everybody is confronted with on a daily basis.
When it comes to antibiotics or other drugs I would tentatively agree, as those are direct applications to the body besides the norm.
So yeah, it is easier to discard theories than to come up with a good one myself, I'm still clueless :D
14:54 If you don't like a video, then stop watching it. Why do people want to spend time typing a message to someone knowing it will make them feel bad? Me personally I LOVE these video's, they take me on a trip I never knew was this complex and beautiful, I thank you for that :)
Thanks for this amazing video, I've been following you and real engineering since the beginning, it's been an awesome adventure. This video in particular feels like you just read my mind.
I just found this channel about a year ago and it’s my go-to when I’m feeling curious. So, honestly thank you for what you do and for being open about what gets to you. I feel very lucky to have found a channel that preaches real science and real life! Keep up the amazing work!
I can’t tell you how much I appreciate you putting in your sources. This Miya have been weeks of research out into 17 minutes of easily digestible info
I very much appreciate that you supplied references. Online science conversations should always have references. Keep up the good work!
I was a fan of this channel since Real Engineering announced that it was happening and I have not been once disappointed with the content. Keep up the amazing work Stephanie, as they say haters gonna hate!
Not much of haters out there, all those commenters said they liked the video they just didn’t think she had a good voice for narration. Don’t think anyone hates her
@@TKUA11 You obviously didn't read all the comments shown; there were at least three anti-evolution comments and one general anti-science comment.
And "haters gonna hate" doesn't always mean literal hate. It encompasses negativity of all kinds, including passive-aggressive.
Unless you've had a public platform with a big following, you can't really understand the toxic levels comments can get to. And it's worse when you're a female because of general systemic sexism, and disturbingly-obsessive misogynistic trolls online whose only purpose in life seems to be to make any prominent woman miserable.
This is wonderful information!! I am 78 years old and have been allergic to lots of things all my life, tho thankfully not to the point of death, just eczema and sneezing & eye-reactions. As a result, I’ve kept up with the research all through the years. This is the most amazing presentation I’ve ever seen! Thank you!! 👍🏻❤️❤️❤️
I just found your vids recently and have been binging! They're truly next-level engaging and informative. In a sea of "infotaining" UA-cam, you stand out in quality and style.
Excellent vid, as usual!! Keep up the good work and important 'self' moments!
Don't let the negative people get you down.
One can 'not like' something and/or disagree with something without being rude, crude, and abusive. When some are negative like that, it says much more about them...not you.
More relevant to this vid...
I've had allergies my entire life. Mostly Hay Fever (pollens), cat dander, soaps/detergents, a couple medications and foods. My allergies were much worse when I was younger. But over time and by not always rushing to take medications for pollen allergies mainly, unless I absolutely had too, and letting my immune system deal with them, they became less sever. Until Covid...but again, I am giving my immune system the time and space to naturally deal with the changes.
As for cats. I found a stray a long time ago. Took him to the vet for medical care. I really liked that cat...there was something special about him. Asked the vet about my cat allergy. He said: 'if I can naturally deal with my immune response (no meds) for about 3 months that my immune system would adjust'. It did.
I had Artemis (my cat) for almost 15 years.
My first video of you I watched and it's very well made . You have no reason to doubt yourself , considering how successful you are here . It's funny how the human mind tends to focus on the small negative things , instead of the much larger pool of positive things right in front of us . A survival behaviour that when you learn how it works , you also learn to ignore it . Stay positive ! Cheers !
It also doesn't help that the most toxic people are often worryingly obsessive, focusing amplified vitriol.
You are so good at explaining. This was a super complex topic but u presented it so well
I love how this gets recommended to me my third week after severe hay fever because of cottonwood trees XD still working on getting rid of the lingering bronchitis.
I loved this channel... keep up the good work. It's kind of hard to find videos like this, i appreciate your hardwork... it must be very hard. One solid sub.
I really appreciate how your content is based on studies and how you bring that to the forefront.
This channel is so wholesome it’s heartwarming to watch your videos first thing in the morning. In addition to being educational, they’re put together quite well. ^__^
love your videos. very educational and by far not an annoying voice. some ppl just wanna see others fail or find „bad“ things to bring others down so they feel better about themselves.
Amazing Video, well explained, and the narrator sound calm but enthusiastic, and that is the best feature of this channel ! thank you Stephanie
Your videos keep getting better. Your documentary litteraly forge this stuff in my mind.
To add to the discussion of strange allergens, I'm allergic to abrupt temperature changes. I'm not sure why, and it could be genetic or a side effect of some other condition. But my reaction is immediate and vicious, often covering my entire body(and sometimes the inside of my throat) in hives. It's not my only allergen, I also have more typical ones like dust, cat saliva, oak mold, and others. But it's worth discussing because while it is an allergic response, I am unsure if there could or would be a potential evolutionary reason for such a reaction.
I follow your videos now since a long time and they are amazing and progressed so we'll both in visualisation and also storytelling! Keep up that great work!
This video is so cool! I loved the narration and the way the subject was evolved. It answered many questions I had about allergies. Awesome job!
I literally asked myself this question yesterday, thank you this was great!
Amazing Detailed Content!
Keep up the good work. Highly appreciate your content
Loved the video! I was reading about the shellfish allergy thing and the proteins that make up the exoskeleton of insects and the cell walls of fungi are similar which can explain why people have some shellfish allergies.
I love how you make sure to cover any probable questions that may arise and answer them appropriately. Keep up the good work 👍👍
I used to be addicted to opiates and just about every opiate binds to histamines/ acts like histamine (not exactly sure which) but causes a histamine rash when you inject and miss a vein. Wonder if that place any part is the evolution of it
Sure, not that evolution is going to "know" what an injection is. Evolution is blind and random. But any response that you have is part of an evolutionary pathway that for whatever reason, provided our ancestors with better survivability.
The bit in this video about sickle cell anemia... NO good reason for that to exist at all!!! But in places where malaria is high and endemic, sickle cell allowed people to be somewhat immune to malaria and just... SURVIVE! Long enough to have kids. That's all that evolution does. You don't see sickle cell in places where there is no malaria. The detrimental aspects of it are far too bad if there are plenty of partners around that do NOT have it.
An outstanding job! I"ve been looking for this article all of my life and I'm 78.Thanks😜
First time listener....Great video. Really enjoyed it. My girlfriend is allergic to just about everything. She sounded just like your description in the beginning. I sent her this link. It is an interesting mystery with regards to allergies. Never thought about it as much until I stumbled upon this video. Great content and a great voice. That's all I need. :) Subscribed.
This is a great video; I knew nothing about this topic before, and this video has really opened my eyes.
Thank you for sharing this interesting research about allergies. Could you make a video about fibromyalgia?
It really breaks my heart when I see negative comments to a such a informative video, go girl you are delivering much needed information to the masses.
I LOVE YOU CHANNEL SO MUCH. I am always disappointed when i check and havent found a new one from you or the real science guy. do you have a patreon?
nice video. well constructed, concise and flows well from point to point.
Взахлёб посмотрела все видео с канала. Мне очень понравилась твоя прекрасная и понятная манера изложения материала. Ценю твое умение видеть красоту в процессе познании мира.
Огромное спасибо тебе за твою работу. Пожалуйста, продолжай в том же духе. Жду новых видео, подписалась.
Наконец-то многое стало понятно :)
‘Cause evolution is allergic towards traits which makes you not have allergies.
Allergi-ception
This was the first of your videos I saw. You are amazing. Keep up the good work.
Well compiled and explained. The what, how and why are the pillars of any scientific explanation. Good work as always. Could be more specific like when you say the proteins are similar, do you mean the structure or the sequence etc. I know you make it for common people to understand but sometimes this kind of detail can help many people who are comfortable with such details. Thank you
For the record
You are awesome 😊👏
Some people don't write it here but
You are Awesome your naration really make it worth watching.
Idk why everybody is thinking somebody is attacking her. I have a clue, cause she is a female??
Ah allergies… the reason I can never own a cat, even though they’re so cute 😭😭
@Not Berber Same things with dogs, but they lick you instead of rubbing your skin.
@@truestopguardatruestop164 Dogs that lick are being submissive to you, not dominant. Actually, if a dog pulls at your pant legs, growls or acts like they are entitled to sleep wherever they like (including your bed) THEN you have a problem with a dog that thinks they own you. :/
Your channel is awesome and I really enjoy it! Thank you for all the information keep up the great work!
Wow! Never saw the comments before. Unbelievable. Just found your channel recently and have been going through all the videos. I very much enjoy and think your narration is really excellent. Keep doing what you're doing! I wish i could do what you do
I really love this amazing channel
wow.....this channel is litt...😍😍😍😍
you are the best
I just found your videos through the algorithm. They're brilliant!
really good explanation, clears many of the doubts, loved it
you dont haev an annoying voice, youre a great narrator and i think youre videos are wonderfully educational and fun to watch
never give up, keep fighting
I think it’s just people who are biased against female voices, I too personally prefer deeper male voices for narrations, it’s why a lot of documents have deep male voices narrating. I don’t know the physiology behind it but I for one know I definitely prefer male narration, not that her voice is bad.
POV: You’re looking for the negative comments that everyone is talking about
P.s. I loved learning more about why I keep dying bc of tree nuts
Awesome... Nice work..
Plz keep doing it and spread knowledge
@Real Science
There is a mistake and some oversight in this video. I am myself a mast cell expert, so I obviously know more than what is possible to show in such a video on a generalist channel, so I will not go into much detail. This is not to vote down the video, simply some precision. In fact, I love your channel and liked this video.
The mistake: mast cells do NOT die after degranulation. They release the contents of specialized granules, which form the majority of the cytoplasm of these big cells. In fact, mast cells can continuously release some content in a controlled fashion.
Precisions: IgE binding to its receptor (and the induced cross-linking, meaning 2 IgE must bind to 1 antigen to activate 2 receptors) on mast cells is only one factor inducing their degranulation. Many "toxins", as presented in the video, can cause degranulation by IgE-independent pathways, either by general Toll-like receptors or by specific endogenous receptors (such as bradykinin or endothelin receptors). Examples include venom peptides. Another precision, illustrating the "toxins" hypothesis, involves the mast cell granule contents. Everyone knows about histamine, the small catecholamine that is the target of most anti-allergy medications. But the granules main contents are proteases, which form up to 35% of total protein content of a mast cell. These proteases are key to degrade many exogenous toxins, many of which resemble signalling peptides of our own system.
As for IgE, the evolutionary analysis of immunoglobulins shows the overall genetic plasticity of most Ig families except IgE: it's always there, and never more than one isoform.
Further reading:
Open Access: onlinelibrary.wiley.com/doi/10.1111/all.14881 The authors of this recent review include a who's who of world experts on mast cell biology and clinical significance.
I love your American accent it's relaxing, thank you for educating the world, and sharing your findings with us all. I know how long it takes to make a video and how much effort never mind the research too.
Don't care what others say, you are doing great. Just keep making fabulous videos like this so that we can keep learning more.
It is not easy to get 500K + people to listen to you...
Great stuff!! Keep up the good work! I fwd these to friends in the medical profession who also really like it.
First time here. Good content. I particularly liked the way the music paired with the dialogue/visuals.
In relation to this hopefully you can also create a vid about autoimmune diseases . It has always fascinated me as to why our own immune system would attack our own body. Great content btw.
Thank you, body, for trying to kill me every time you see a cat or eat parsley. Why do you not give a crap about bee stings though? i don't get it, but i guess there is an explanation...
I actually had allergies for a number of things, like pollen. And i did get rid of it by breathing exercises. Except for cats(( And recently parsley. And it's different in every case. For cats it's basically sneezing or my nose gets blocked. For parsley... i basically suffocate. But only if it's fresh. If it's cooked (heated) - no problems whatsoever.
I heard a while back if you eat localized honey it should help most of your allergies. Something to do with the bees and the flowers they get their pollen from.
Heating (cooking) changes the proteins, so they no longer fire up response in your body. Same for me for apples and walnuts - when cooked in a cake, no problems. Raw - oopsie.
😦
You’re doing great. Love learning here. Thank you
Im allergic to cats and have one, everyday I wake up struggling to get air past my throat until I take quadruple the prescribed dose of albuterol to reopen my lungs. Thanks immune system 👍
does your doctor recommend overdosing?
Finally, the lovely science channel has uploaded!!!
I was literally just thinking about this topic. So interesting and informative! Really well-presented findings.
bless this video, and these linked references aw yis
y'all work so damn to produce hard such quality output
The weird thing is I was playing outside on grass in forrests and so a lot as a child even when growing up and I deffenitly had some accidents and things like that but with about 14 I one day suddenly got a massive pollen allergy I never had before and since then I still have pollen allergy
Am I allergic to dogs because they carry fleas and parasites easily?
Or just from lack of exposure? I love dogs so much it's so sad.
Might be the fleas.
There are hypoallergenic dog breeds that cause little to no immune response (depending on your level of sensitivity), like Bichon Frise, Basenji, Poodle, Maltese, Havanese, or Portuguese Water Dogs. They shed very little, thus less allergens in the air.
@Lone Starr Why am I so allergic to poodles then?
Thank you, this is very informational and well researched
Wow, that was great info! Thanks for making this and sharing with us!
No allergies. I always found it hard to relate. I enjoyed the presentation. Thank you for the science.
What about allergies that make you stuffy? There's no expulsion there, just slow suffocation.
Insightful and Good presentation. Please do more videos
i found your voice VERY calming and nice
I had allergies to processed cheese when I was a kid, my upper lips would swell up. (yes, I had an incredible sterile upbringing)
but now it's gone when I am an adult, why ? Do I have worms?
Your body probably cleared out those IgE antibodies at some point from lack of use. Antibodies and the cells that make them don't live forever. Same with the mast cells they're attached to.
@@thisisatonofbs But that raises the question, how were they gotten in the first place? Presumably they've had processed cheese more than once as an adult and not re-acquired the allergy. So why did they get the allergy once but not again?