On time restricted eating, Alan apparently didn’t hear your interview with Satchin Panda. Dr. Panda said you need at least a 12 hour window without eating during the night for your GI to clean, repair, and reset just like your brain does when you sleep. Your gut takes 5 hours to digest your last meal then another 7-8 hours for repairs. According to Dr. Panda, if you eat right before bed it will interfere with sleep quality and without the time to reset there’s an impact on blood glucose and weight. Episode #221
Clearly solid information but is Alan deliberately saying things in slow motion with unnecessary terminology or is this just how he speaks. I feel like you could rework the delivery of this kind of content and it would be much more successful and easy to follow. Some diagrams might also help.
This episode answered a lot of questions I didn't know I had and really cleared up where I should go from here...for me, low saturated fat, and fewer calories. Calorie counting is the only way I can spot my overeating days lol. I'm east asian, and tiny (not tiny enough at the moment) so its really easy to over consume my days calorie needs.
@@happyhealthylife4ever calorie counting works. It's difficult for many people to count calories accurately, but it does work. I lost 10lbs last year myself by counting.
@@happyhealthylife4everCalorie counting is not exact, but people can and do limit their calorie intake by doing it. I think you are stuck on the 'exact math' here.
Wrong: Lustig showed that in an ISOCALORIC shift FROM FRUCTOSE to Glucose without any weight loss... Fatty liver is resolved with shifting energy intake ONLY FROM FRUCTOSE into Glucose. So... IT IS NOT simply Energy intake excess that causes NAFL... it is PRIMARILY Fructose Toxicity.
Many thanks for this Simon, it was super Interesting. I would have loved to see your host share hos thoughts on the following based on any prevailing evidence. (1) As far as fats, research suggesting inclusiin of transfat regardless of whether or not food is eaten to meet calorie balance or even hypocaloric state is alleged to contribute to visceral fat accumulation and/or development of NAFLD (2)Various You Tubers citing studies that they state overwhelmingly support the role of coffee and Apple Cider Vinegar as mitigating the risk of NAFLD and preventing or minimizing the risk of visceral fat accumulation, all things being equal. (3) The idea floating around out there that it is not so much higher PFT in certain ethnic groups that predisposes them to more easily accumulate additional visceral fat and or be more prone to developing NAFLD. Rather. Rather the primary driver of this is more lack or very low lean muscle mass levels relative to visceral fat levels. And development of greater lean muscle mass via increased progressive resistance training can mitigate development of NAFLD and T2D
Just an anecdote, but a few years ago I had some bloodwork done, liver enzymes popped, got an ultrasound and a NAFLD diagnosis shortly after. Did keto for a while, which eventually turned into OMAD, and about three months in I got blood drawn again and liver enzymes were normal. I also lost 40 lbs during that time, but I was really big to start so wasn't lean by any means. I eat a lot of nuts, seeds, avocado, cauliflower, berries, and greens. My main proteins are chicken, fish, and tofu. Red meat and dairy only on special occasions. The type of fat definitely matters, and the intermittent fasting has been great for me. I don't need to be convinced that it's any greater than plain calorie restriction. It just works for me and my psychology.
interesting. im T2, dutch-indonesian, 6'0", now HbA1C of 5.9 @ 165lb It wasnt until I LOST weight to a BMI of roughly 18% that I saw major decreases in blood glucose. Ive never heard that theory about what constitued overweight being so different depending on race.
Hi Everyone, I'm eager to learn which aspect of our conversation resonated with you the most. Feel free to share any additional queries you have on this subject in the comments below. I'll be sure to incorporate them in our next meeting.
Not sure if my mental fog was bad today but I found this convo hard to follow. I might try watching again another day as I have NAFLD among other conditions so its pretty important. I follow a WFPB SOS diet and lost weight for a time but I have been gaining again this year. Its been a tough year with a lot of stress going on and I have begun to reach for a bit too much dried fruit which I know I need to cut out but it has become my new comfort food. I find it hard to be active enough too due to anxiety about going out anywhere numbers of people will be.
Maybe try being active insides if you have the economical ressources to buy some gym material to combinate with calisthenics? Good luck and much strength :)
Have you listened to Dr's. Nadir Ali, or Sten Ekberg, or Jason Fung, or Pradip Jamnadas? I too had just been diagnosed with fatty liver and DM type II this year. In 9 mo. I am down 40 lbs, A1c was 10.1 now 5.6, and bad liver enzymes now normal. I reversed fatty liver by intermittent fasts, two meals a day in 6 hour window, 25 gm carb diet daily. Just walking, some weight resistance exercise. 62 yr old! I feel so much healthier.
@@theonewhoknows62 ekberg is a charlatan... Intermittent fasting is alright, but please don't follow his dietary advice, at least not on the long term. Congrats for your weight loss.
Very nice episode, very informative. I did not know that unsaturated fats were good for NAFLD reduction, and saturated fats bad. This is additional evidence to reduce saturated fat - for liver as well as atherosclerosis.
Wow.. well done Simon on your extremely low visceral fat. Looking for best diet solution for reducing visceral fat for my husband. Reduce carbs? We're wfpb no sos. No processed foods accept for occasional whole-wheat pitta bread from Asda. Gym, pilates and walking.
Have you tried counting calories? I'm also wfpb, but I gained some weight around the middle during the pandemic. I was able to lose it by weighing my portions and logging in Chronometer. It was a good reminder that portion sizes still matter, even on a wfpb diet.
How much of his diet is already vegetables? I believe high water, high fiber, polyphenol rich diet with some seaweedvariants in there would be your best bet.
Great podcast, thank you Simon and Alan for that. Could not find any show notes on the website. Saw a description of the conversation but nothing more than that. Am I looking at the wrong place? Perhaps I am accustomed to the show notes that Dr. Peter Attia puts on and this is not of the same depth?
So excess energy is the main and possibly only culprit to NAFLD, but adding a high-fructose drink leads to a more fatty liver than adding lactose. I take that to mean that excess fructose makes people hungrier.
I also saw a study where they overfed people by either saturated fats or fructose and the 20% of kcal from saturated fats diet increased visceral fat more.
Simon asks such great questions that even though I am in disagreement with many of his conclusions, I find his podcasts extremely informative. With regards to a high saturated fat, zero or near zero carb diet and liver function with weight loss, I would bet dollars to donuts that liver health improvements will be observed in almost every scenario. I would challenge any researcher to demonstrate otherwise. Obviously, this does not apply where carbs are introduced in any significant amount or where weight gain is not induced.
On time restricted eating, Alan apparently didn’t hear your interview with Satchin Panda. Dr. Panda said you need at least a 12 hour window without eating during the night for your GI to clean, repair, and reset just like your brain does when you sleep. Your gut takes 5 hours to digest your last meal then another 7-8 hours for repairs. According to Dr. Panda, if you eat right before bed it will interfere with sleep quality and without the time to reset there’s an impact on blood glucose and weight. Episode #221
your videos are the ones I don't mind being long, I can't get enough listening to both of you , thanks for great work
Same, Simon's podcast is the only one worth 2+ hours!
Clearly solid information but is Alan deliberately saying things in slow motion with unnecessary terminology or is this just how he speaks. I feel like you could rework the delivery of this kind of content and it would be much more successful and easy to follow. Some diagrams might also help.
This episode answered a lot of questions I didn't know I had and really cleared up where I should go from here...for me, low saturated fat, and fewer calories. Calorie counting is the only way I can spot my overeating days lol. I'm east asian, and tiny (not tiny enough at the moment) so its really easy to over consume my days calorie needs.
@@happyhealthylife4ever calorie counting works. It's difficult for many people to count calories accurately, but it does work. I lost 10lbs last year myself by counting.
The types of different saturated fats differ in their harm risk profiles. We need better nuance.
@@happyhealthylife4everCalorie counting is not exact, but people can and do limit their calorie intake by doing it.
I think you are stuck on the 'exact math' here.
Always so informative! 👍
Wrong: Lustig showed that in an ISOCALORIC shift FROM FRUCTOSE to Glucose without any weight loss... Fatty liver is resolved with shifting energy intake ONLY FROM FRUCTOSE into Glucose.
So... IT IS NOT simply Energy intake excess that causes NAFL... it is PRIMARILY Fructose Toxicity.
Many thanks for this Simon, it was super Interesting. I would have loved to see your host share hos thoughts on the following based on any prevailing evidence.
(1) As far as fats, research suggesting inclusiin of transfat regardless of whether or not food is eaten to meet calorie balance or even hypocaloric state is alleged to contribute to visceral fat accumulation and/or development of NAFLD
(2)Various You Tubers citing studies that they state overwhelmingly support the role of coffee and Apple Cider Vinegar as mitigating the risk of NAFLD and preventing or minimizing the risk of visceral fat accumulation, all things being equal.
(3) The idea floating around out there that it is not so much higher PFT in certain ethnic groups that predisposes them to more easily accumulate additional visceral fat and or be more prone to developing NAFLD. Rather. Rather the primary driver of this is more lack or very low lean muscle mass levels relative to visceral fat levels. And development of greater lean muscle mass via increased progressive resistance training can mitigate development of NAFLD and T2D
Great video 🔥
Fantastic discussion on fatty liver
Gawd we love Dr Alan aka The Pancreatic Prince...
He sounds very much like Robert Lustic
Anorexia can fat liver underweight?
Thank God Alan isn't treating patients!
How so?
Just an anecdote, but a few years ago I had some bloodwork done, liver enzymes popped, got an ultrasound and a NAFLD diagnosis shortly after. Did keto for a while, which eventually turned into OMAD, and about three months in I got blood drawn again and liver enzymes were normal. I also lost 40 lbs during that time, but I was really big to start so wasn't lean by any means. I eat a lot of nuts, seeds, avocado, cauliflower, berries, and greens. My main proteins are chicken, fish, and tofu. Red meat and dairy only on special occasions. The type of fat definitely matters, and the intermittent fasting has been great for me. I don't need to be convinced that it's any greater than plain calorie restriction. It just works for me and my psychology.
man i love Alan. always has interesting things to say.
Awesome! I know it’ll be a good one when Alan is on the show!
interesting. im T2, dutch-indonesian, 6'0", now HbA1C of 5.9 @ 165lb
It wasnt until I LOST weight to a BMI of roughly 18% that I saw major decreases in blood glucose.
Ive never heard that theory about what constitued overweight being so different depending on race.
Hi Everyone,
I'm eager to learn which aspect of our conversation resonated with you the most. Feel free to share any additional queries you have on this subject in the comments below. I'll be sure to incorporate them in our next meeting.
Not sure if my mental fog was bad today but I found this convo hard to follow. I might try watching again another day as I have NAFLD among other conditions so its pretty important. I follow a WFPB SOS diet and lost weight for a time but I have been gaining again this year. Its been a tough year with a lot of stress going on and I have begun to reach for a bit too much dried fruit which I know I need to cut out but it has become my new comfort food. I find it hard to be active enough too due to anxiety about going out anywhere numbers of people will be.
Maybe try being active insides if you have the economical ressources to buy some gym material to combinate with calisthenics? Good luck and much strength :)
Have you listened to Dr's. Nadir Ali, or Sten Ekberg, or Jason Fung, or Pradip Jamnadas? I too had just been diagnosed with fatty liver and DM type II this year. In 9 mo. I am down 40 lbs, A1c was 10.1 now 5.6, and bad liver enzymes now normal. I reversed fatty liver by intermittent fasts, two meals a day in 6 hour window, 25 gm carb diet daily. Just walking, some weight resistance exercise. 62 yr old! I feel so much healthier.
@@theonewhoknows62 ekberg is a charlatan... Intermittent fasting is alright, but please don't follow his dietary advice, at least not on the long term. Congrats for your weight loss.
What a good discussion! Liver health is outside my scope, but I still found the talk easy to follow. Great job gentlemen. Thank you.
Fructose is considered the villain because of the tireless efforts of Drs Lustig and Johnson?
Wish mic did not block view of his mouth, as makes it harder to understand what he is saying without seeing his lips move
Very nice episode, very informative. I did not know that unsaturated fats were good for NAFLD reduction, and saturated fats bad. This is additional evidence to reduce saturated fat - for liver as well as atherosclerosis.
Wow.. well done Simon on your extremely low visceral fat.
Looking for best diet solution for reducing visceral fat for my husband. Reduce carbs? We're wfpb no sos. No processed foods accept for occasional whole-wheat pitta bread from Asda. Gym, pilates and walking.
Have you tried counting calories? I'm also wfpb, but I gained some weight around the middle during the pandemic. I was able to lose it by weighing my portions and logging in Chronometer. It was a good reminder that portion sizes still matter, even on a wfpb diet.
How much of his diet is already vegetables? I believe high water, high fiber, polyphenol rich diet with some seaweedvariants in there would be your best bet.
The study Alan mentioned about 80 minutes in compared 100 g of sugar in cola to 50g of milk sugar? That doesn't sound like a fair fight.
I haven't finished listening, so it might be covered, but what is the recommended level for fasting insulin
W
Great episode 🔥
Simon, I appreciate the quality and depth of your work. Thank you.
Great podcast, thank you Simon and Alan for that. Could not find any show notes on the website. Saw a description of the conversation but nothing more than that. Am I looking at the wrong place? Perhaps I am accustomed to the show notes that Dr. Peter Attia puts on and this is not of the same depth?
So excess energy is the main and possibly only culprit to NAFLD, but adding a high-fructose drink leads to a more fatty liver than adding lactose. I take that to mean that excess fructose makes people hungrier.
I also saw a study where they overfed people by either saturated fats or fructose and the 20% of kcal from saturated fats diet increased visceral fat more.
I think there is a problem with the dairy guidelines if people choose high sugar low fat chocolate milk over 3.5% fermented kefir.
Please, invite another nice irishman Ivor Cummins to talk with you and Allan. He is very knowlegeable.
Simon asks such great questions that even though I am in disagreement with many of his conclusions, I find his podcasts extremely informative.
With regards to a high saturated fat, zero or near zero carb diet and liver function with weight loss, I would bet dollars to donuts that liver health improvements will be observed in almost every scenario. I would challenge any researcher to demonstrate otherwise. Obviously, this does not apply where carbs are introduced in any significant amount or where weight gain is not induced.