TWiV 858: The vax of life with John Mascola

Поділитися
Вставка
  • Опубліковано 12 гру 2024

КОМЕНТАРІ • 52

  • @MrOzzyCam
    @MrOzzyCam 2 роки тому +16

    Thanks Vincent and TWiV team for another episode!

    • @GadZookz
      @GadZookz 2 роки тому +2

      Mr. O’Cam, You must behave! 😃

  • @lesfaby8997
    @lesfaby8997 2 роки тому +11

    TIMESTAMPS
    03:34 Guest biography
    09:30 Vaccine research center info
    12:54 VRC works on what vaccines
    17:30 Status of HIV vaccine development
    Links for this episode
    20:27 Accelerated COVID-19 vaccine development
    23:20 Why mRNA vaccine focus
    24:25 How development was sped up
    26:07 VRC role in operation warpspeed
    29:23 Warpspeed vaccine candidates
    32:50 Goal vaccine in a year
    33:19 Common standards for vaccine trials
    36:40 2 Protein vaccines may come out
    37:42 how to handle variants
    41:31 protection against all symptomatic disease
    less than 50 pct after 6 months while serious disease
    protection persists
    44:01 vaccines designed to avoid serious disease
    45:30 monitoring adverse events
    47:22 Can we increase pct vaccinated
    48:59 US Seropositivity rate
    49:50 Lessons for the future
    50:53 what is needed for other viruses
    51:49 unanswered virologic or immunologic gaps
    54:30 surge capacity plan
    57:55 flu vaccines
    58:33 RSV vaccines
    1:02:18 panel summary
    1:03:27 Letters
    1:03:30 Paula deer
    1:07:22 Sue Ellen trusts TWiV guests more than others
    1:10:19 Saskia omicron spread by immune evasion
    1:12:20 Stephen preschooler vaccine trials
    1:16:05 J.P. Rosalyn Franklin grave
    1:17:47 antigen tests question
    1:28:49 Anthony General Lees
    1:30:02 Damien TWiT humans can't create life
    1:33:06 Alex non virus comments
    1:33:48 Vaccine Townhall
    Audio Timestamps by Jolene Thanks
    1:34:00 Weekly Picks
    1:34:02 Brianne How Sesame Street is Handling the Pandemic
    1:35:52 Rich Zamboni: How it works
    1:39:00 Alan How lightning starts
    1:40:52 Vincent Buon-A-Petitti
    Listener Picks
    1:43:21 Meika Wordle

  • @_c_y_p_3
    @_c_y_p_3 2 роки тому +16

    This was another ⭐️ episode. John Mascola was one of those recent best of TWIV episodes. I know I say every show is the best but to hear his story, I sorta feel he coulda been on for longer because you only touched the surface of most of the topics mentioned. As always, much love from Sweden.

  • @zinnialady5153
    @zinnialady5153 2 роки тому +7

    I enjoy each of you for different reasons. Brianne I enjoy your insights and how you are always thinking and questioning. You love when you can pick someone’s brain I’ve noticed. You love learning something new.

  • @luisfernando-mm3jt
    @luisfernando-mm3jt 2 роки тому +5

    Love all you do thanks for the wisdom

  • @westfield90
    @westfield90 2 роки тому +6

    What an absolutely interesting brilliant show with a very articulate guest and great questions from the twiv team.

  • @clippybrokentooth1305
    @clippybrokentooth1305 2 роки тому +4

    Looking forward to watching 👍🏼

  • @luisfernando-mm3jt
    @luisfernando-mm3jt 2 роки тому +4

    Brianne is Allways always laughing... Love her... And the others to😊😊

  • @TB-ck1jr
    @TB-ck1jr 2 роки тому +1

    I think our family ran into a bad batch of PCR. My husband started with symptoms on Sunday and tested positive at home twice. The next day, I had a sore throat. I tested positive at home that night. My son's nose was starting to run a little too. Tuesday morning, I took myself and the kids for PCRs. My husband went on his own in the afternoon. On Friday (husband still symptomatic, I'm still symptomatic, son more symptomatic, and daughter had started) we got our PCRs back. Husband was positive, but the 3 of us that tested in the morning came back negative. I tested myself and the kids again at home and we were all positive. Took the kids to get PCRs again on Saturday and me on Monday. All three now positive. I'd assume that we tested too early the first time except for the fact that I tested positive at home the day before the PCR. 🤷‍♀️

  • @beproudskeptic1522
    @beproudskeptic1522 2 роки тому +1

    Thank you, please keep doing this, I so enjoy it. I have learned so much.

  • @simontemplar404
    @simontemplar404 2 роки тому +5

    Amazing episode. This story would make a great "science" movie.

  • @emerraldx
    @emerraldx 2 роки тому +5

    another point on inherently trusting TWiV guests when encountered on other sources, any professional not too busy to communicate with the public and wise enough to accept an invite from the TWIV team deserves my attention, not to mention I am sure Vincent is rather particular with his guest selection which immediately gives their words more credibility in my eyes

  • @monicamolloy5105
    @monicamolloy5105 2 роки тому +3

    Thank you all. That was very helpful, informative and fascinating. R/ Monica.

  • @jenniferwinsor7740
    @jenniferwinsor7740 2 роки тому +3

    I'm watching this episode waiting to lose power with the January 29th snowstorm. We're in the potential jackpot snowfall amount in Plymouth County, MA. Enjoying the behind the scenes information of the covid 19 vaccines and operation warp speed.

  • @Gieza-Brake-Pahl
    @Gieza-Brake-Pahl 2 роки тому +15

    This was really interesting!
    A couple of requests
    1) as a sailor I would appreciate if you would add the wind speed and direction to your weather reports
    2) as a diabetic overweight older guy I am trying to lose weight to reduce my comorbidities should I catch Covid, I would therefore appreciate if you would stop mentioning food, especially Italian food.

    • @cynthialeech2507
      @cynthialeech2507 2 роки тому +18

      Listen to TWIV as a podcast while walking. The time and pounds fly!

    • @christopherrobinson7541
      @christopherrobinson7541 2 роки тому +3

      @@cynthialeech2507 Opening your wallet on a windy day is not to be recommended.

  • @bid6413
    @bid6413 2 роки тому +7

    Very interested in anything related to the “long-haulers” issue. Thank you for everything.

    • @ScotHarkins
      @ScotHarkins 2 роки тому +1

      I have an in-law now 20 months into severe long-COVID that came on after a severe two-week illness (not hospitalized). But without a positive clinical test they do not qualify for one of the nearby long-COVID clinics...nobody could get tested on Kansas City at that time (March/April 2020).
      It feels like long-haulers need to ban together, but that it incredibly difficult while living with the ongoing post-acute sequele issues. These people are getting screwed out of disability and proper care and therapy.

    • @ghaclord
      @ghaclord 2 роки тому

      @@ScotHarkins the struggle is horrible. My adult daughter in the same situation. So disabled she can’t work and activities of daily living are challenging.

  • @bid6413
    @bid6413 2 роки тому +2

    Great to get an inside look. Thanks.

  • @susanryan622
    @susanryan622 2 роки тому

    On youtube there is no boundary between pics. And as a very low-level participant this was a great, great “epitope”!

  • @randmorf
    @randmorf 2 роки тому +2

    Yes 'The Atlantic' Magazine. Went to their website to check out the latest news and came across the article "The Case Against Masks at School -- Districts should rethink imposing on millions of children an intervention that provides little discernible benefit". I did not read further as in my book masks are effective not only against all variants of Covid-19, but also just about every other respiratory disease. So, be aware that publications recommended on TWIV (around 1:35:08) also can contain articles written by the opposition.

  • @fanfreluchefanfreluche1246
    @fanfreluchefanfreluche1246 2 роки тому

    Thank you all of TWIV for yet another most interesting and informative podcast…I’ve never been
    disappointed on the contrary…we learn and get entertained…your podcasts have almost become
    addictive…Weather here in Gaspesie…rigorous winter….

  • @bcase5328
    @bcase5328 2 роки тому +2

    Unfortunately those under 65 years old, don't remember what diseases can do. They grew up in the age of vaccinations, and take the protection for granted. So, they fear side affects more than disease.
    With monitoring, how about fill out our knowledge of human immunity, microbiology, virology, and ecological systems on the excuse of readying for space colonies/stations.

  • @JimK0QJC
    @JimK0QJC 2 роки тому

    Sorry an off topic question: is the lighting in the incubator florescent? Maybe an explanation for the green tint on the video form the incubator.

    • @lesfaby8997
      @lesfaby8997 2 роки тому +1

      @James Lauridson Vincent has LED lights that are color adjustable. He chose the color because of his shirt color.

  • @Artbyevelyn
    @Artbyevelyn 2 роки тому +1

    What are your thoughts on the new NeocoV found a day ago in China by scientist

  • @TechnoLawyer
    @TechnoLawyer 2 роки тому +1

    I agree we need to stop looking at case numbers. My wife, kids, kids and myself (all vaxxed) all had covid recently. It was a cold circa 2019, take some dayquill and you're fine. If it weren't for the positive rapid tests and the current times, I wouldn't have thought twice about it.
    Cases like we had are irrelevant, and that is so very many people right now. Unless the concern is a run on dayquill? 😆

    • @moniquedewyk6341
      @moniquedewyk6341 2 роки тому

      A lot of the stuff that is reported about numbers of cases is reported just to scare people into getting a vaccine, staying home, wearing a mask and social distancing. Two year after all this started that does not seem to have worked.

  • @annaraj7958
    @annaraj7958 2 роки тому

    Can you explain why I get severe allergic reaction( anaphalysis) for the Pheifer vaccination? Since i was vacinated I have problem with liver and skin and swollen my arm etc

  • @alandun27
    @alandun27 2 роки тому +1

    Listener pick - Kudos to Brianne! also for that smile . . .🙂. . . never stops . . .

    • @alandun27
      @alandun27 2 роки тому

      @@TonyFisherPuzzles STATEMENT - This is not at all what I meant. I LOVE HER SMILE which is CLEARLY not fake but intrinsic to her open and kind and generous nature! Sheesh!

    • @skepticalbadger
      @skepticalbadger 2 роки тому

      @@TonyFisherPuzzles Pathetic comment. You should be ashamed.

  • @etc6615
    @etc6615 2 роки тому

    “Mantra” ???
    Such empathy! How do you hope to influence if this is how you talk?

  • @GadZookz
    @GadZookz 2 роки тому +4

    There is only one way for scientists to create life and that is the old fashion way; no degree required. 🙂

  • @dkmj
    @dkmj 2 роки тому +3

    Go Brianne!

  • @ScotHarkins
    @ScotHarkins 2 роки тому +1

    I'm really trying to find _anything_ about safety in a crowded canoe (dragon boat) with 20 paddlers out for 1-2 hours getting a great workout. We require paddlers be fully vaxxed + boosted, but unmasked only inches away from a bench mate and a couple of feet from people ahead and behind.
    No cases yet in several months, but holy cow with Omicron we paused for the peak and will resume in February.

    • @ScotHarkins
      @ScotHarkins 2 роки тому

      ...and the health department says "rowing is safe". We are way way way closer together than rowers. UGH!!!

    • @Starclimber
      @Starclimber 2 роки тому +1

      I commend you for your prudence.

    • @skepticalbadger
      @skepticalbadger 2 роки тому +2

      In that setting you are VERY well ventilated, but of course it's an infection risk. Fully vaxed you are at low risk of serious disease. Do you want to avoid your sport forever to prevent getting infected? I doubt it. Just get on with your life; I say this with all good wishes.

  • @ScotHarkins
    @ScotHarkins 2 роки тому

    I'm so tickled to hear someone mention TWiT (Leo Laporte) on TWiV. Yes, TWiT might have ventured into fantasy. Maybe someday...in the future...the far future.

  • @GadZookz
    @GadZookz 2 роки тому

    Any offspring, naturally conceived at the Incubator, should receive a complete scholarship to study virology at a world class university.

  • @ianlight2141
    @ianlight2141 2 роки тому

    The protein virus also good globally !

  • @charlestongren2860
    @charlestongren2860 2 роки тому

    107

    • @charlestongren2860
      @charlestongren2860 2 роки тому

      Lightning. Creation of live exp.

    • @Starclimber
      @Starclimber 2 роки тому +1

      @@charlestongren2860 Congrats on the primordially soupy comment.

  • @walterredfield9379
    @walterredfield9379 2 роки тому

    Why is the girl laughing all the time?