AMYLOIDOSIS: Part 1: Definition, Historical aspects & Properties of Amyloid

In this part 1 of "amyloidosis" i have described the definition, historical aspects and properties of Amyloid. Visit ilovepathology.com / for more topics in Pathology!
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AMYLOIDOSIS 1
Is a condition associated with number of inherited and inflammatory disorders
In which There is deposition of Predominantly Extracellular fibrillar proteins RESULTING IN Tissue damage & functional compromise
These are Aggregates of MISFOLDED proteins and are insoluble.
historical aspects:
“amylim” a latin word means “starch”
Matthias Schleiden a German Botanist was the first to use the term “amyloid” in botany, for starch, referring to“starch-like”.
German pathologist Rudolf Virchow (1804 - 1881) applied it in the medical literature in 1854.
used the word “Amyloid” to describe some deposits in nervous system which showed the same color reaction with iodine and sulfuric acid, i.e. a change from brown to blue, typical to starch
In the later years it was found that the chemical nature was unrelated to starch but proteins!
Yet.. The name “amyloid” still remains
Probably because of Virchow was considered as one of the most valued scientists of his time
In the later years it was found that the chemical nature was unrelated to starch but proteins!
Amyloid proteins: Properties
Amyloid is not a single entity
More than 20 different proteins can aggregate to form fibrils.
The mechanisms of formation are different.
Therefore amyloidosis should not be considered as a single disease… rather, a group of diseases with deposition of similar appearing proteins

[@103srijhaasridhar8]

These lectures are my saviors during these online learning times... Making Robbins into understandable form.... Thanks a lottt n it will be so helpful if u try covering all the topics if possible... It's my request... ✌

[@Tunir007]

though you don't get many views, your videos are really good sir and are helping me a lot through medical school. Keep em coming!

[@ilovepathologyVijayPatho]

Thank you very much. Glad you liked it. Do circulate :-)

[@abiyeepeya-kiri2152]

Like.. who are those that dislike this video.. you don't know how you just arranged my work and lecture note. God bless you Sir..
Wished I could like more than ones..

[@adnan.q.753]

This is very thorough. And I like how you use Robbins as your primary source of information.

[@mappthub941]

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[@123coolghost]

THANK YOU SO SO MUCH!! IVE BEEN TRYING VERY HARD TO UNDERSTAND THIS! And YOUR VIDEO MADE IT POSSSIBLE.
GREAT JOB SIR😄

[@ayushirajput.7423]

Really working in my studies keep uploading more lectures sir.

[@Buzzybeebuzzybee]

Sir, it is really very helpful.. it covers every single thing. Have to say it made pathology easier. ❤️ Thank you sir

[@varun4975]

Thanks your way of speaking and teaching is really calming🙏

[@ayishashahar1105]

Sir ,nvr discontinue frm doin contents😖 u r a real tym saviour😥also covr rest of the topics sir😭

[@shivanichhabra1166]

Thanks for this wonderful video. My mother was suffering from Amyloidosis for last years. We visited many hospitals and doctors but didn’t get good results. Then I visited to planet ayurveda and they gave her some Ayurvedic medicines and she got well after using that .

[@art_for_life123]

Ur videos are like life safer it's the simplified form of robbins please upload more videos sir

[@PraveenKumar-ye4ib]

Very very thank you sir. U make it so easy. Pls upload more videos from systemic pathology.

[@Nisha-kl8rl]

Planet Ayurveda’s approach to Amyloidosis treatment is amazing. I feel like a new person

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Love your vids sir. Please continue the good work

[@ilovepathologyVijayPatho]

Thank You very much :-)

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Thank you sir🙏🏻
In less time good content is explained 😊

[@anshusen3439]

very helpful video on such a complicated topic for mbbs students, thank you very much sir

[@DS-eq4si]

Sir, please make such lectures for genetics and infectious diseases also, for PGs 🙏🙏

[@sharathsai6486]

🙏🙏🙏 tq sir for making this concept understand quickly.

[@Dr.HERbivore]

Your videos are so easy to understand ! can't thank enough ❤️ please give some tips too for pathology learning .

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I have also lichen amyloidosis
and follow planet ayurvedic treatment on last 7 days , u tell your friends that , what is the current status & tell me

[@AnjaliYadav-qm9nq]

Thanks sir...
It's really helpful

[@sandeshpandey186]

Thank you sir . Your videos are very helpful 👍.
Keep uploading!

[@ilovepathologyVijayPatho]

Thanks . Glad you liked them . Good luck

[@kubrasheikh5325]

Excellent video with clear and simple explanation

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Thanks for the video..

[@phobos_miner4288]

Fantastic video. Minor comment in minute 7:25 you mention that APP increase, not always, negative APP decrease.

[@theneetsquad6508]

Wonderful lecture sir.. Can you please provide us these notes?

[@priyajha1384]

Please make more videos sir
It is a excellent summery of robbins

[@mybookismylife.2798]

U r brilliant 👍... very beautifully explained... Thank u so much sir 👍🙏🏿❤️

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Thank You Teacher 💕💖

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Sir plz make video on testicular tumors and ovarian tumors.

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Awesome sir...thank u so....much

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Sir it is very useful to us please upload more and more videos 🙏🙏

[@thepedodontist]

Amazing video sir this make pathology so easy , sir plz upload more video and on all topics . Thank u

[@SOMERANDOMPREPPY]

SIR PLS MAKE A VIDEO ESPECIALLY ON SYSTEMIC LUPUS ERYTHEMATOSUS

[@ilovepathologyVijayPatho]

It’s done already
Check the latest videos

[@ilovepathologyVijayPatho]

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Really awesome sir..🙏🙏🙏
Explained everything.....
Keep uploading patho videos sir.......☺☺

[@vishnu3526]

Thank u so much sir. Pls do more videos on systemic pathology.

[@AR-jy7pm]

Thanks a lot,sir ❤️

[@abinashpadhy4457]

My father got diagnosed with AL amyloidosis ...m looking for s amyloidosis specialists in india ... kindly guide me

[@mostafamagdy559]

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Ur lecture's was superb sir..plzz.upload autoimmune disorders also

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Thank you Sir
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Please post more videos of more chapters.

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Sir,i request you to upload lectures on immunity also..Pls sir

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I thing that the information share for the death rate is wrong in your video so please check it once and rectify it if u can . Thank you .

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nice but try to slow down a little....so we can assimilate properly

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Excellent sir

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Your videos are very helpful but if you could get a better mic it would be awesome

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Have you covered whole pathology in your videos???

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Pls make more videos

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Thnk

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Is there any treatment for macular amyloidosis. my skin become dark now and its spreading

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Mine too

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very nice lecture

[@obiwan922]

kindly someone help me with this concept. .... ''when we say beta pleated sheet formation , do we mean the structure of each single protein (within the amyloid fibrils; i assume amyloid fibrils are composed of group of proteins) is beta pleated sheet. Or the fibril as a whole forms beta pleated sheet. " ..i actually didnt understand the beta pleated sheet idea in amyloid formation. from the basic idea, I just know beta pleated sheet is one of the secondary structure of any single protein. Thanks.

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Nice lecture

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[@Dr.lost586]

I love your videos

[@minnahahamed9069]

It is very concise and clear notes. Most needed. Thank you sir

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Nice video sirr

[@jagrajsingh6494]

I was diagnosed with Lichen Amyloidosis. My whole body got covered with rashes and papules and I was having severe itching. I was rushed to the hospital and was started on antihistaminics, but no relief was there. Next day, I came back to home and was very much tensed due to this. One day I was surfing for the internet and mistakenly opened one site named as Planet Ayurveda. I ordered Amyloidosis care pack online and used it for 3 months. It gave me much relief in my symptoms.

[@subhrangshuchatterjee850]

Sir i have lichen amyloidosis on my both leg since last 15 years.
How can i get rid from it

[@jannatulasrar3553]

Do you have IBD?

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@@jannatulasrar3553 do u have this to

[@rohithpidaparthy1619]

Which book have u followed sir?... so that I can refer it in book too..

[@studywithhasan8682]

thanks for the video (y) it helped a lot

[@jaysoni9618]

Sir, can dental students follow your lectures or it will be too lengthy??
Please answer 🙏

[@ilovepathologyVijayPatho]

By all means..general pathology lectures are for all..the concepts will be understood better..

[@Surajkumar-eo3ub]

Curcumin capsules from planet ayurveda are very helpful in amyloidosis disease

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Mattias scleiden I heard this name second time...one in inter biology and same here

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its great!!

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please upload more videos

[@yashugowda3900]

Best!

[@skmedlife3533]

Thanx u sir

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Why did you post other chapters

[@stutimitra8315]

It's very helpful. Thank you!

[@ilovepathologyVijayPatho]

Glad it was helpful!

[@_botox0165]

Supperb 😉

[@islamicfollower7654]

Can you provide pdfs? Helpful ppts

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Sir are you following ramdas nayak?

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*SUBSCRIBED* 😊😊😊🤗

[@daisydcruz6076]

amyloidosis care pack helps to reduce this type of problems. my sister was struggling with same problems, then she'd use planet ayurveda products and now she's ok. i think you also have to try these products with the help of consultations by dr vikram chauhan.

[@balathanan7583]

Is it from robbins 😉

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Ok thanks for mentioning

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Sir avaaj thoda kam pad raha hai thoda jor se bolo na please baki video ekdum ready hai .,...

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❤

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Dil sulphuric acid

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ಇಂಪ್ರೆಸ್ಸಿವ್

[@lordjim24]

Why are all these videos done by Indians with strong accents? Can barely understand.

[@abinashpadhy4457]

My father got diagnosed with AL amyloidosis ...m looking for s amyloidosis specialists in india ... kindly guide me