Clinical Trials | Different Phase of Clinical Trial | What is Clinical Trial | Clinical Pharmacology

Important Link-
Experimental Animal- • Common Animals Used in...
Preclinical trial- • Preclinical Trial |Int...
Drug Discovery Phases- • Drug Discovery Phases ...
Therapeutic Index- • Therapeutic Index | Dr...
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - play.google.co...
Clinical trials are experiments or observations done in clinical research. Such prospective biomedical or behavioural research studies on human participants are designed to answer specific questions about biomedical or behavioural interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial - their approval does not mean that the therapy is 'safe' or effective, only that the trial may be conducted.
Phase 0- Phase 0 trials are optional first-in-human trials. Single subtherapeutic doses of the study drug or treatment are given to a small number of subjects (typically 10 to 15) to gather preliminary data on the agent's pharmacodynamics (what the drug does to the body) and pharmacokinetics (what the body does to the drugs
Phase 01- Often the first-in-man trials. Testing within a small group of people (typically 20-80) to evaluate the safety, determine safe dosage ranges, and begin to identify side effects. A drug's side effects could be subtle or long term, or may only happen with a few people, so phase 1 trials are not expected to identify all side effects.
Phase 02- Testing with a larger group of people (typically 100-300) to determine the efficacy and to further evaluate its safety. The gradual increase in test group size allows for the evocation of less-common side effects.
Phase 03- Testing with large groups of people (typically 1,000-3,000) to confirm its efficacy, evaluate its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow it to be used safely.
Phase IV- Postmarketing studies delineate additional information, including the treatment's risks, benefits, and optimal use. As such, they are ongoing during the drug's lifetime of active medical use
Description Credit- wikipedia
Get in touch with the solution by just clicking following links-
Facebook Page- / pharmavideo
Facebook Group- / solutionpharamcy
Instagram- / solutionpharmacy
Mail Us for Free Pharmacology Materials- [e-mail]
LinkedIn- / pushpendrakpatel

[@PharmacyAdda]

This topic i studied last yr but understood today🙏

[@solutionpharmacy]

Good. Thank you for feedback

[@sanjibmishra4055]

U HAVE DESCRIBED ALL THE PHASES OF CLINICAL TRIALS VERY NICELY THANKS YOU

[@gautamitirpude8555]

I always used to think that the subject pharmacy is very hard to understand but when I started attending your lectures u made so easy sir... Thank you very much.

[@solutionpharmacy]

Great. Wish you all the best

[@gayatrisharma9418]

Great explanation sir
And the white bord informations r very good way for presenting topic

[@solutionpharmacy]

Gayatri Sharma Thank you so much

[@tusharthakur8600]

I am b-pharm graudate trying to get in clinical research for the last 1 year in mumbai. Now i understand clinical research is only for masters degree holder. ☹️
Very informative pointers for beginners sir. Thank you.

[@sushmasah6946]

What all we wanted ..
We found everything in ur video sir .
Ur videos makes harder topic to understand in easier way.
Thankuh sir😊

[@solutionpharmacy]

Great. Thank you so much for your feedback

[@abdulraufjamali4113]

You have these lectures slides?

[@sanjibmishra4055]

THANKS YOU U HAVE DESCRIBED ALL THE PHASES OF CLINICAL TRIALS

[@JohnC-24]

Sir ji thanks for the video. Your teaching style is very understandable and simple.

[@solutionpharmacy]

Thank you

[@watchman7642]

Came across this video and its very lucidly explained. Correction- its not congress but council for both ICH and ICMR.

[@solutionpharmacy]

Thank you. Yes you are right. I did mistake

[@abuzarkhushal8733]

Thank you sir you are explaining in a very easy manner.

[@solutionpharmacy]

My pleasure

[@rohachaudhary3449]

THANK YOU SOOOO MUCH SIR !♥️
SARAY CONCEPTS CLEAR HOGAYE HAIN.
YOU'RE THE BEST TEACHER🌸🌸🌸

[@solutionpharmacy]

Thank you so much for your kind support and feedback

[@praveenpatnaik8971]

I am an Electrical Engineer, just started watching this video to gain some basic knowledge on clinical trial
But I seriously gained something more than basics
Thanks for your lucid & simple explanation.
Great work
Thanks & Regards

[@solutionpharmacy]

Great. Happy to know that i could give you some knowledge. Thank you for your feedback sir.

[@bunkerskk4686]

Great 😂😂

[@rohitpawar577]

Thank you sr because I watch your video my concepts is very clear,its very helpful for Gpad preparation

[@solutionpharmacy]

Thank you. All the best

[@sharptech.747]

Rohit pawar bro it's gpat not gpad

[@samikshyapoudel3039]

thank you so much sir... this video give me proper knowledge about drug development process... it will be very beneficial for my upcomming exam .... love from Nepal

[@solutionpharmacy]

Thank you so much

[@SUNILSAHU-vq4fp]

I clearly understand this topic this is so helpful thank you sir your videos provide best knowledge about our pharmacy field and for GPAT

[@solutionpharmacy]

Thank you so much.

[@mayurchauhan3444]

Awesome thankyou sir
Today is my exam nd your video is helpfull to me.

[@solutionpharmacy]

mayur chauhan most welcome. All the best

[@manishpatil7980]

Easy to understand n all concepts are clear

[@solutionpharmacy]

Thank you so much

[@jyotipawade5982]

Very useful sir thanku so much
please make video on NDCT Rules 2019

[@drawesome9317]

Wow what a quote at the starting of the video...thanku so much sir

[@sureshnaik4792]

Sir AAP bahot achha padhate he ..me aapka savi vedio dekhta hun .. dekhne me savi samajh me aajata he. .achha lagta he ..thank u sir

[@solutionpharmacy]

Thank you so much

[@digambarmalihindi]

Great explaination sir , your command on topic is amazing , thank you sir for providing this systematic and useful information for us

[@solutionpharmacy]

Thank you. Its my pleasure

[@hajiraabbasi62]

Thank you so much sir for explanation ❤

[@sagarahire4074]

In the whole video all information is pretty good. But there is some corrections in video ICMR/ICH "C" stands for Council not Congress.

[@solutionpharmacy]

Yes. I have admitted my mistake eralier. Here again i am seeking sorry for that mistake.

[@subhrajyotimaji9971]

Your explanation is best....

[@solutionpharmacy]

Thank you

[@Clariwell]

Really good brief about Clinical Research.Thank you for making awareness about job ready career

[@solutionpharmacy]

Thank you for your feedback

[@taukeeraalam9419]

Best information and clear and clean.. well explained ♥️😍..thank u so much sir.😍♥️

[@solutionpharmacy]

Most welcome. Happy that you got satisfied.

[@bunnyyoutube7738]

Such video needed in times of such pendamic for awareness

[@solutionpharmacy]

Thank you

[@ug.pharmalogo1854]

Sir ka video bahut bahut help ful rahata hai iss leye mai add skip nahi karta hun ..ap log bhi skip mat kiya kijaey ❌

[@solutionpharmacy]

Thank you so much. Bahut support hoga isse hame

[@user-bp3hu9yl3e]

excellent presentation kindly share with me clinical trail related more videos to clear the concept.Thanku

[@usharamakrishna2306]

Very simplied yet thorough knowledge of the given topic . excellent presentation sir

[@7760087800]

This is so much informative thank you very much sir

[@solutionpharmacy]

Welcome

[@dileepkushwaha5789]

Very helpful video thanq so much sir

[@solutionpharmacy]

My pleasure

[@heenabhardhwaj2701]

Thnq sir 🙏🙏

[@PharmacyAdda]

Doing great work sir 🥰🙏

[@solutionpharmacy]

Thank you

[@pharmacyeasy1995]

🙏. Sir plz upload SAR on dictionary channel

[@kunalkumar7404]

Very helpful thank you sir ..

[@solutionpharmacy]

Thank you

[@saidurrohman5393]

Thank you so much sir .. please make more videos, i strongly support you sir

[@solutionpharmacy]

Thank you. We have finished all most all
Topics of cology.

[@vloglover4033]

Thankyou sir this video help me a lot

[@dr.reenubajpai5829]

Well structured content.Kindly tell something about protocol writing at different phases!

[@solutionpharmacy]

Thank you and really sorry this videos are as per 4 sem syllabus.

[@saumyaupadhyay4853]

Very well explained....Thank-you sir!

[@solutionpharmacy]

saumya upadhyay Thank you so much for valuable feedback.

[@dradityaselectro-homeopath732]

Great explanation Sir 🙏

[@solutionpharmacy]

Thank you

[@surekhashridharpurohit2493]

Very well explained sir.Thanks for sharing

[@solutionpharmacy]

Most welcome

[@dr.mdateequrrehman9473]

Good explanation
Thanks

[@solutionpharmacy]

Thank you

[@akshayjoshi2601]

Sir how much time does it take for clinical trials for non invasive electronic medical device

[@abhinandanjain2399]

Thank you so much sir🙏🙏🙏🙏🙏🙏🙏🙏.

[@kimmmmmy9818]

Nice explanation sir. Thank u so much . It was really a good presentation about diff phases .

[@deeptimayeedhal7330]

Well done sir 👍

[@solutionpharmacy]

Thank you

[@anjalimehra8149]

Thank you sir 🙏🤗

[@nizemshaheenshaik603]

Tq you so much sir...bohoth ache sey samaj ah Gaya..lots of love 💞

[@mathumitha6340]

Sir, I request you to upload videos in english, since I dont know Hindi and it would be a great help sir.

[@manishanavghare-dwarankar1840]

excellent sir

[@solutionpharmacy]

Thank you

[@ratneshchavan4756]

Thanks 🙏

[@subhammishra8168]

Sir please upload other subject like medicinal chemistry, physical pharmaceutics, organic chemistry sir

[@mr.schoolhacker6713]

Bhai Muja Aapse AKkam Haa

[@mr.schoolhacker6713]

aap Khase Hoo

[@kajalsaini1253]

Thnx sir for giving us... Information about this topic...

[@solutionpharmacy]

Welcome

[@sonalidabhade456]

Really very nice sir

[@kavitarawat7569]

Thanks for sharing

[@solutionpharmacy]

My pleasure

[@rahulmahajan8376]

sir your videos are very helpful for us

[@solutionpharmacy]

Thanks alot

[@SumanLata-zp8od]

Very nyc video sir

[@solutionpharmacy]

Thanks and welcome

[@amareshkumargautam3480]

Nice concept Sir 👍 keep it up 💪

[@solutionpharmacy]

Amaresh Kumar Gautam Thank you

[@manmeetsingh6902]

Nice information

[@solutionpharmacy]

Thank you

[@AbhishekKumar-jc3fj]

Thank you so much sir ❣️

[@solutionpharmacy]

My pleasure

[@gautamitirpude8555]

Sir u r great

[@solutionpharmacy]

Thank you

[@drxpratap5057]

Good topic sir 👌 thanks for video

[@solutionpharmacy]

Pratap Bachhar Welcome. Its my pleasure.

[@heenaKhan-im8kn]

Rules & regulations for animal ad human experiment .....sir ye question b krwa dijiye

[@easystepsfishcare5416]

It was really helpful

[@solutionpharmacy]

easy steps fish care Thank you

[@abhishekkumarvishwakarma492]

Very nice sir
No any dought

[@solutionpharmacy]

Thank you so much

[@vinaynagar3567]

Nice video sir very useful in time of corona

[@solutionpharmacy]

Thank you

[@gautamitirpude8555]

Very nice sir..

[@mohdateek9362]

Sir aapne Short me bahut achha samjhaya hai

[@solutionpharmacy]

Thank you

[@vaishnavjay]

ICMR stands for Indian Council of Medical Research (ICMR). You mentioned C as Congress

[@shubhisharma8284]

C= conference

[@solutionpharmacy]

Sorry jay ji. Galti se ho gaya

[@shubhisharma8284]

It's ok ☺☺

[@manishapathak842]

Very nice

[@solutionpharmacy]

Thank you

[@cool_buddy7755]

Thank you. It was very useful.
Can you tell me what is the difference between study period and intake period, for a particular disease area?

[@ratneshchavan4756]

First i will find out cause of disease,
Then how much time to spread of disease and how to prevent it..

[@milind0808]

Good information sir very well explained

[@solutionpharmacy]

Thank you

[@उमंगपटेल]

Very nice information sir👌👌👌👌

[@solutionpharmacy]

Thank you

[@dr.shaguftaparveen2582]

Sir please give a lacture on the topic clinical research

[@shashankagiri9631]

sir please make a vedio on investigational new drug

[@ShubhamYadav-cu5zg]

Clinical trails for tooth regeneration and repair through biological way in future.
please make a video on it

[@saroshsaroshali9654]

Sir aap k lectures bht achay hain..please stages of drug developement pe video bnayein complete...formulation , up scaling?

[@solutionpharmacy]

Thank you. Thats not in syllabus of cology right now

[@soumyaagrawal2023]

Thankyou sir for this helpful video

[@solutionpharmacy]

My pleasure

[@HomeHome-he2xq]

Thanks sir ji

[@solutionpharmacy]

Welcome

[@hamidulmallick3297]

Sir I can not crack GPAT 2019 , nd I'm too much upset till now and lost my self-confidence ; can you please upload a video on how can I get over from this situation nd how can I again start preparation to get a good rank in GPAT 2020 ,?

[@vrindacreation]

Sir plz ek sequence me video ko playlist me upload kriye . searching me prob ATI h....I like to see your videos in detail

[@solutionpharmacy]

Playlist bana hua hai. Go to pharmacology 1 and 2 and then 3

[@akash.solanki]

Thank you

[@shubhamkubade6829]

Sir please make vedio on schizophernia diseases

[@vrushalimane8042]

It's really helpful to all

[@ramakantmahato4378]

Thank you Patel sir

[@uddin2309]

this should be in more detail.. but good explanation

[@solutionpharmacy]

kumar gourav Thank you. Yes it should be. But this topic is included as a sub topic and thats why it is short

[@nutritionistsabir.]

Sir bobybuling drugs or Seprate video plzz

[@manthanjain6697]

Nice teaching 👌, thanks sir

[@sikanderjitsingh2476]

Sir very informative video 🙏

[@solutionpharmacy]

sikander jit singh thank you so much

[@nehapal6896]

I read article that is EMG triggered nmes and tens bialteral arm training rct based how we make a clinical trial which point I put in positive and negative

[@indrajeetrathod9047]

Sir biostatistics pe video banaiye please

[@ceri2468]

Hi Sir, please explain double blinding, how it's so effective when nobody knows Anything about the trial, neither the doctor nor the patient. Please help🙏

[@solutionpharmacy]

Ok. I will but after finishing syllabus

[@rajeshther14]

Clinical Trail based on Clinical research
Fullform of ICH meaning totally wrong and Ethical clearance,
ICH- International confrence on hormonization of technical for the registration of pharmaceutical intented for humen use.
Ethics committe or IRB means Institutional Review Borad- playing important role for subject safety end efficacy for involve clinical trail.
USFDA - United state Food and drug Administration
ICMR - Indian counsil of medical research

[@solutionpharmacy]

Rajesh ther Thank you for your correction. Maine pahle is coment ko dekha nahi tha. Sorry for that.

[@missqueen9234]

Thank u sir i hve my exam tommorow plz pray for me hope i write well

[@user-ct8nl5ne1v]

Hi

[@vijaykannaujia6867]

Sir plz explain the natural products 8sem B pharma

[@rashmigoswami4047]

Sir I have a question....It is generally said that bactericidal and bacteriostatic drugs are antagonistic to each other but why some combinations such as cefexime and azithromycin are used

[@solutionpharmacy]

They are not antagonists

[@artworld2720]

Great respect .

[@AbuHasan-fw6zd]

Great Job sir

[@solutionpharmacy]

Thank you

[@deekshabahuguna115]

Wowwww❤️ thank you so much sir🙏

[@solutionpharmacy]

Thank you