Episode 12 Dale Bredesen discusses the metabolic factors underlying Alzheimer’s Disease

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‘Would you rather remember: the latest episode of Friends, or how to speak?’ asks Dr. Dale Bredesen, a nationally-recognized expert on neurodegenerative diseases.
We don’t have to think about the answer to that question. In fact, we are biologically programmed to preserve speech and forget the television show. But physiological changes occur as we age, which begin to affect our ability to speak, walk, and remember names and faces.
The most extreme and recognizable form of this is Alzheimer’s Disease, which Dr. Bredesen states is the third leading cause of death in the United States. He has come up with a novel therapeutic approach that first investigates the underlying metabolic changes leading to the disease.
Bredesen’s approach, called MEND (metabolic enhancement for neurodegeneration) helped a 65-year-old woman recover her functional memory, after her first physician had written her off as bound to the same demise of her mother, who suffered and died from Alzheimer’s Disease.
Bredesen shares these and other insights in this episode of STEM-Talk, where he and host Dawn Kernagis engage in a rich and thought-provoking conversation about the future of treating neurodegenerative and other diseases.
Bredesen has been on the faculty at UCSF, UCSD. Currently, he divides his time between UCLA and the Buck Institute for Research on Aging, of which he is founder and CEO: buckinstitute.o...