T-Cell Memory and Exhaustion

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  • Опубліковано 25 кві 2016

КОМЕНТАРІ • 17

  • @alexandrekassiantchouk1632
    @alexandrekassiantchouk1632 3 роки тому +4

    Very en lighting presentation and very useful - even now with COVID patients, 75% going cytotoxic T Cells route (vs 25% CD4 - B cells - antibodies route). And when failure (because of viral load - T Cells exhaustion? - and/or because of second phase of filtering out T Cells best match to antigen built because of preexisting conditions, and/or because thymus in old people shrank/malfunctions) - cytokine storm.

    • @mmganesh6087
      @mmganesh6087 2 роки тому +1

      hello mr alex, I just saw this video for a few minutes. I am a layman. I am not able to follow this lecture because of the technicalities involved in it. I would like you to educate me on this question that I have. Will it be a good idea to stimulate the body using vaccine when a person already was infected and then recovered ? Is it not exhausting the t cell into activation because of this repeated stimulation that the vaccine will do ,to get the body immune system activated for 3 or 6 months by this constant production of antibodies ?

    • @Ace-fu4mu
      @Ace-fu4mu 2 роки тому

      With the reputation of the CDC...
      1. The Tuskegee Study
      2. The Guinea Pig Kids
      3. 1976 H1N1 debacle
      to name a few...
      I, a lay person rather educate myself than listening to those with an agenda.

    • @mmganesh6087
      @mmganesh6087 Рік тому

      @Cuenta falsa Tq for the reply. The answers result in further queries. For eg, " the lifetime of proteins ( spike proteins ) is measured in days"
      In that case, antibodies will be there for a few more days or so and then start waning.
      We have a cdc director who says " we did not know that antibodies wane" .It is so hard to hear such talk.
      Doctors and pharma ceo say " more antibodies is better"
      When waning starts quickly , then it calls for frequent vaccinations

  • @a.santos5961
    @a.santos5961 6 років тому +2

    I love it !

  • @sarahconner9433
    @sarahconner9433 Рік тому

    8:06 anyone who uses the word "epitope" is extremely intelligent... And someone you should pay high attention to....And is doing something important to solve and end human suffering..... Thank you doctor for your groundbreaking work!!❤️👏❤️👏👏🐱

  • @glendonpflugrath8811
    @glendonpflugrath8811 2 роки тому +1

    Incomplete. End of lecture is missing.

  • @TheFearedwarrior
    @TheFearedwarrior 2 роки тому +11

    Seems timely especially with all these boosters they want us to get. :(

    • @rshore081
      @rshore081 2 роки тому +1

      Agree, research research research!

  • @basetelzagallai7444
    @basetelzagallai7444 5 років тому +2

    Who is the speaker please?

  • @mechcntr7185
    @mechcntr7185 5 років тому +1

    He is mispronouncing every 3rd word making it difficult to listen to.

    • @mechcntr7185
      @mechcntr7185 4 роки тому

      @Samuel Kotler Yes you are saying he is better than me..better than you as well right?

    • @bobleclair5665
      @bobleclair5665 2 роки тому

      If you watch enough videos,it’ll start to jell, we are lucky to have these great minds and a collage education at our fingertips, be careful,it can become addictive,

    • @MPRA1000
      @MPRA1000 2 роки тому

      Il faut être né poëte pour être un grand orateur. Il n'est point poëte. One of the biggest frustrations in communication is the inability to understand what a person is saying. This can even lead to heated arguments, family disputes, and lovers' quarrels. Many of us fall into the "I can't understand you" or poor diction category.

    • @bobleclair5665
      @bobleclair5665 2 роки тому

      MPRA 1000, wearing masks don’t help

    • @noa2453
      @noa2453 2 роки тому +1

      He just has an accent. It happens.