Approach to anemia with hepatosplenomegaly

Let us discuss the approach to an important clinical case scenario of anemia with hepatosplenomegaly.
Time codes:
0:00 Introduction
1:03 Demographics and its significance
10:15 Chief complaints
12:30 HOPI
16: 00 Dds of anemia with HSmegaly
17:39 H/O etiology
22:55 Past and treatment history
30:59 H/o complications
32:38 Antenatal /Birth, diet, development and family history
42:07 Summary
49:18 General examination
53:33 GI examination
1:02:47 Diagnosis
1:04:35 Investigations
1:18:20 Discussion on Transfusion dependent Thalassemia
1:22:46 Iron overload in TDT
1:34:30 Newer therapies