Gonna cover a cardio ward this week and was struggling with rate/rhythm control agents. This vid came in just in time n clarified my doubts. Thank you sir you're such a blessing
These effects complement each other rather than contradicting: • A stronger contraction (due to higher intracellular calcium) helps pump blood effectively. • A slower heart rate reduces myocardial oxygen demand and improves cardiac efficiency.
Hey @Medicosis I read that Digoxin helps in stimulating the release of Ach from the vagus nerve which results in activating Gi protein and inhibition of cAMP that leads to inactivation of the Ca2+ channel and secondly Gama i activates the K+ channel resulting in the release of K+ from cells. As a result, Digoxin causes hyperpolarization and increases the time of Threshold Potential. So Digoxin helps in reducing Ca++ in Pacemaker cells by stimulating Ach release but increases Ca++ in non-pacemaker cells by inhibiting the Na+ and K+ ATPase?
Hey medicosis today was my urology exam and there was a question I didn't know the answer Why alkalosis cause tetany ? I know it's something about calicum level but I don't understand what it is exactly can you explain it to me please
High pH makes the albumin more anionic which will bind calcium strongly thus there wont be free calcium available. That causes Tetany. Medicosis should correct me if Im wrong :)
@@Zainab-nt4jr you know calcium is highly competitive. So when its around, it doesnt let other cations bind on receptors thus it kinda inhibits excessive firing of neurons. But when its not around, god dammit. Then sodium takes over and it fires!
❤️ Cardiac Pharmacology Course: www.medicosisperfectionalis.com/
In german green is grün not vert
All videos are not playing on this channel
I can’t believe I’m watching a pharmacology video and I’m smiling doing it. Thanks so much❤
I shared your UA-cam channel with all my friends in cairo university
I love your easy way in teaching 🖤
Big 🤍 for you from Egypt 🇪🇬
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I appreciate you!
After 2 years of medical school - Digoxin finally makes sense. Thank you
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Gonna cover a cardio ward this week and was struggling with rate/rhythm control agents. This vid came in just in time n clarified my doubts. Thank you sir you're such a blessing
My pleasure 😇
Good luck 🍀
What the flip I just realized I've been watching wrong content THIS IS IT... THIS IS THE CHANNEL I NEED... explains it soo well you get it all
Watching from Kenya 🇰🇪🇰🇪🇰🇪thank you medicosis
i wish you a very happy, fruitful life teacher, you saved a lot of patients and doctors-to-be's life... may god bless you everyday and every moment
Thank you!
You too!
Would you please help me by sharing?
I cant thank you enough for this, you're literally going to save my grade
I can’t believe I’m enjoying digoxin videos haha thank you for this! I wish i have known your before during med school days. You are amazing!!
I'm so glad! Thank you for your kind words!
i'm here just to give a like because u deserve it , i have a lot of things to read and my exam is soon
i will watch it later !
Good luck 🍀
I love you Mr Medicosis Perfectionalis, brother.
Love from Bangladesh❤❤
You're very welcome!
Would you please help me by sharing?
I hope you open other closed videos these are all very helpful
Thank you! I needed clarification on digoxin.
My pleasure 😇
digoxin does two opposite things. if it is increasing heart contractility than why is it decreasing the heart rate.
Because it has vagus-like effect
These effects complement each other rather than contradicting:
• A stronger contraction (due to higher intracellular calcium) helps pump blood effectively.
• A slower heart rate reduces myocardial oxygen demand and improves cardiac efficiency.
Hey @Medicosis I read that Digoxin helps in stimulating the release of Ach from the vagus nerve which results in activating Gi protein and inhibition of cAMP that leads to inactivation of the Ca2+ channel and secondly Gama i activates the K+ channel resulting in the release of K+ from cells. As a result, Digoxin causes hyperpolarization and increases the time of Threshold Potential.
So Digoxin helps in reducing Ca++ in Pacemaker cells by stimulating Ach release but increases Ca++ in non-pacemaker cells by inhibiting the Na+ and K+ ATPase?
Superb.. No words to thank you!!😍
Thank you 😊
Excellent summary. Thanks.
My pleasure!
You are a hero thank you
I'm sharing this with my friends
Thank you so much 😊
Please make the other videos to open 🙏🏻
🫀 Cardiology Playlist: ua-cam.com/play/PLYcLrRDaR8_dc8IwFj3UcZKkZimMFMCwC.html&si=mz0oqFg-xsdyNTJU
Right on time !!! THANK YOUUU
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Thank you thank you i love you
Thanks Dear sir!!!
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So many thanks
Amazing work
Thank you 😊
omg,this video totally solve my problem!
Thank you 😊
You are great !
Thank you 😊
Feeling confident in Digoxin now 😁
Great 👍
Thanks a lot ❤️
My pleasure!
Why digoxin used in atrial fibrillation mechanism???
Love your videos !
Thank you 🙏
I did not get the streptococci point😔
Amazing explanation
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مبدع Creative, thank you,🔥🤍
Thank you 🙏
You are amazing 😮❤❤
Thank you medicosis ❤🌹
My pleasure 😇
Hey medicosis today was my urology exam and there was a question I didn't know the answer
Why alkalosis cause tetany ? I know it's something about calicum level but I don't understand what it is exactly can you explain it to me please
High pH makes the albumin more anionic which will bind calcium strongly thus there wont be free calcium available. That causes Tetany. Medicosis should correct me if Im wrong :)
@@rumeysaeed1 aha thank u
@@rumeysaeed1 and what does this has to do with neurons?
@@Zainab-nt4jr you know calcium is highly competitive. So when its around, it doesnt let other cations bind on receptors thus it kinda inhibits excessive firing of neurons. But when its not around, god dammit. Then sodium takes over and it fires!
💊 Pharmacology Playlist: ua-cam.com/play/PLYcLrRDaR8_d5RzuEJprW-NWXTK22ByVC.html&si=MGlX4_a2LlLOo6Ed
Alright, seems this would be useful as usual
Thank you 😊
Really helpful thank you
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Thxxxxx suppperrrr 🤧💗💗💗💗💗
Thank you for watching!
Wonderful
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My hero
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Great 😍🤩
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That actin myosin slap
Hi my friend this cheenal is very good
But I want ade the Arabic translate please
Huge and kiss Ca 😅
❤❤❤❤❤❤
:)
😮😮😮🎉🎉🎉🎉🎉
:)
Awesome explanation
Thank you 😊