Thank you so much sir!! I am about to give a presentation about methotrexate and your video is super fantastic that it was very easy to understand! God bless
Mike, have RA and take MTX 20mg per week. Also take Leflunomide 10mg daily and Folic acid the day before the MTX. I know what the Folic acid is for but are you able clarify how the Leflunomide works alongside the MTX ? The regime is working very well at managing the disease ; just have an overactive curiosity. Thanks
leflunomide is also a dmard(anti rheumatic drug) and works by inhibiting dyhydroorate dehydrogenase enzyme and prevents the rheumatic disease progression therefore giving a double anti rheumatic effect and treating the disease more effectively 😊
I don't understand, in the cancer example the methotrexate doesn't distinguish a cancerous cell from a normal one, right? So the methotrexate is impairing good cells with the bad, right? What does this mean? Same with T helper cells: Just eliminate their function in the body? So if you're on methotrexate you have impaired immune system?
@@katharineharrison9091well it does work fortunately, but it’s so toxic.. I stopped taking it January 2024, so would have been on it for 6-7 years in total and now I’ve stopped I can see my joints starting to swell n disfigure 😢 I started on higher doses then down to 10 mg..good luck..feel for you
@@ashillingforyourthoughts chill man, I didn’t neck the whole bottle. Just a few pills. Didn’t do much anyways except make me hella sick. Won’t bother again. Appreciate the concern tho.
![Lp. Сердце Вселенной #60 РОЖДЕНИЕ ЛОЛОЛОШКИ [Финал] • Майнкрафт](http://i.ytimg.com/vi/YoR0pAV9FVQ/mqdefault.jpg)
Thank you so much sir!! I am about to give a presentation about methotrexate and your video is super fantastic that it was very easy to understand! God bless
Nice work! Easy to understandthx to the chart!
Thank you sir u r doing a great job 💯👍👏💯
Mike, have RA and take MTX 20mg per week. Also take Leflunomide 10mg daily and Folic acid the day before the MTX. I know what the Folic acid is for but are you able clarify how the Leflunomide works alongside the MTX ? The regime is working very well at managing the disease ; just have an overactive curiosity. Thanks
leflunomide is also a dmard(anti rheumatic drug) and works by inhibiting dyhydroorate dehydrogenase enzyme and prevents the rheumatic disease progression therefore giving a double anti rheumatic effect and treating the disease more effectively 😊
I don't understand, in the cancer example the methotrexate doesn't distinguish a cancerous cell from a normal one, right? So the methotrexate is impairing good cells with the bad, right? What does this mean? Same with T helper cells: Just eliminate their function in the body? So if you're on methotrexate you have impaired immune system?
Correct. Methotrexate leaves the patient with an impaired immune system and increases the risk of infection, sickness and all manner of diseases.
You made it easy sir
Thank you ☺️
Very helpful! Thank you
You are great !! 👏🏻👏🏻❤️
Thank you
I have scleroderma, my doctor prescribed me methotrexate 2.5mg 3 tablets per week w 3Xweek Folic acid.
Does the code chemical of methotrexate contain polythelene glycol?
👍👍
wish I could find a biologic with the same mechanism of action of methotrexate
Perfect
My son take this medicine ..can i ask if he still can take this med even if he had cough??
Please stop it, if he has cough.
Tuwinmadim uzbikchaga tuwintiriwni iloji bormi mini qizim ichivoti bu garmonmi
Such a nasty drug on my system.. my liver is now very damaged. 😢
Get well soon dear 💕
im about to go on it :( Going to have to give up drinking alcohol
How long did you take it? And did you take other drugs or drink alcohol? Asking as I’m just starting it.
@@katharineharrison9091well it does work fortunately, but it’s so toxic.. I stopped taking it January 2024, so would have been on it for 6-7 years in total and now I’ve stopped I can see my joints starting to swell n disfigure 😢
I started on higher doses then down to 10 mg..good luck..feel for you
Missus has SLE and one day she was at work I took a couple to try catch a buzz. Yeah nah. Welcome to vomit city.
Don’t be crazy ! This is seriously dangerous medication if taken at incorrect dosages
@@ashillingforyourthoughts chill man, I didn’t neck the whole bottle. Just a few pills. Didn’t do much anyways except make me hella sick. Won’t bother again. Appreciate the concern tho.
What an absolute fool you are. Its people like you that deserve what you get.