BCG vaccination of healthy human volunteers results in enhanced production of pro-inflammatory cytokines, such as IL-1β, tumour necrosis factor (TNF) and IL-6, when monocytes from these individuals are stimulated ex vivo with unrelated pathogens12. Interestingly, these effects are accompanied by transcriptional, epigenetic and metabolic reprogramming of the myeloid cells in the BCG-vaccinated individuals. The epigenetic changes are manifested as chemical modifications (methylation and acetylation) of the histone, resulting in enhanced chromatin accessibility, easier transcription of genes
مراجعة حضرتك السريعة دي بساعات شرح مع دكاترة تانيين..ربنا يبارك لحضرتك في علمك ويجازيكي كل خير❤
ربنا يكرمك تسلم
الحمد لله انكم بتستفيدوا منها
بالتوفيق دايما
بحب حضرتك اويييييي❤❤❤❤❤❤❤😊
بااااااااااااااارك بيك وجزاك الله خير الجزاء
جزاك الله خيرا يادكتوره
الله يحفظك ويبارك فيكي يا دكتوره🤍🤍
جزاك الله خيراً
الله يباركلك احسن دكتور باثولوجي بجد من الصبح ادور علي دكتوره يشرح كويس ♥️♥️♥️
مش عارف اقول لحضرتك ايه بجد بس ربنا يكرمك والله 🤍🤍 شرح مختصر و وافي فعلا
💚💚💚
ممكن اجابه ااسؤال دة يادكتور Why can the recent immunization against tuberculosis reduce the risk for infection with some viral pathogens?
BCG vaccination of healthy human volunteers results in enhanced production of pro-inflammatory cytokines, such as IL-1β, tumour necrosis factor (TNF) and IL-6, when monocytes from these individuals are stimulated ex vivo with unrelated pathogens12. Interestingly, these effects are accompanied by transcriptional, epigenetic and metabolic reprogramming of the myeloid cells in the BCG-vaccinated individuals. The epigenetic changes are manifested as chemical modifications (methylation and acetylation) of the histone, resulting in enhanced chromatin accessibility, easier transcription of genes
www.nature.com/articles/s41577-020-0337-y
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@@histotubedr.shereenhamed thank you 💙