Smooth Muscle Contraction and Relaxation | Smooth Muscle Physiology | Smooth Muscle action potential

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  • Опубліковано 14 тра 2021
  • In this lecture I discuss physiology of smooth muscle contraction and relaxation.
    Also discuss the MCQ on physiology of smooth muscle contraction and relaxation at the end of lecture.
    A smooth muscle contraction is a type of muscle contraction that takes place within the walls of many of the body’s internal structures such as the blood vessels, organs of the digestive tract, and reproductive organs.
    Unlike skeletal muscles, which are found close to the skin and which perform voluntary movements of the body’s joints like walking or lifting a fork to eat, smooth muscles perform automatic, unconscious functions like pushing the blood through the arteries or digested food through the intestines.
    The smooth muscle contraction differs from the skeletal muscle contraction in that it causes the entire wall of the vessel to undulate, moving as a unit to transport the vessel’s contents.
    Forming an internal layer of the wall of an organ or vessel just behind that vessel’s mucous membrane, smooth muscle is flat and continuous.
    Found lining the walls of such structures as the arteries and veins, the esophagus, stomach, and intestines, and the bladder and uterus, this type of muscle is typically fusiform in shape.
    Fusiform muscle fibers are each shaped like a spindle, and while skeletal muscle fibers can take this shape as well, skeletal muscle contraction occurs linearly in a direction that is parallel to the fiber’s length while smooth muscle contraction involves the expansion and contraction of muscle tissue in multiple directions.
    Smooth muscle contraction therefore produces a kind of undulating, squeezing movement known as peristalsis that pushes blood, partially digested food, and reproductive cells in a single direction in slow waves.
    Within the muscle cell, molecules arranged linearly in filaments called actin and myosin provide the mechanism of smooth muscle contraction.
    By forming rows of interlinked chains, much like chain mail armor, they make contraction in multiple directions possible.
    Several proteins known as calmodulin facilitate this muscle contraction by binding to calcium ions. It is this binding action that changes the molecular structure of the smooth muscle cell and thus brings about the contraction cycle.
    Formation of cross bridge and power stroke are the main steps.
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