Protein Language Models

Language models, such as those used in ChatGPT, have been reimagined for protein modeling, wherein protein sequence patterns are identified and then used to predict new sequences following the learnable parameters. The video explores IgLM as a case study, covering generative language models, controllable generation of sequences, infilled protein libraries, likelihood estimations.
Protein Modeling and Design with PyRosetta and Machine Learning
• Protein Modeling and D...
Video from the Rosetta Commons RaMP Bootcamp (July 2023)
Instructor: Deniz Akpinaroglu (UCSF)
IgLM paper link: www.cell.com/cell-systems/abs...
Credits:
Instructor: Deniz Akpinaroglu (UCSF)
RaMP Director and Rosetta Commons Director: Jeffrey Gray (JHU)
RaMP Program Administrator:Camille Mathis (JHU)
Rosetta Commons Instructional Designer: Ashley Vater (UC Davis)
Video Production: Elizabeth Bonilla (JHU)
Funding: Rosetta Commons, National Science Foundation, and Johns Hopkins University