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डोंगल कि फुहार, लाये फसलो मे फ़ुलो कि बहार | paclobutrazol 40% SC |

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  • Опубліковано 11 сер 2023
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    KUKU FM
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    Paclobutrazol is an inhibitor of enzymes which use cytochrome P450 as a co-factor. Their active site contains a heme center which activates oxygen from the air to oxidise their substrates. The (2S,3S) isomer inhibits the enzyme ent-kaurene oxidase[5][8] which is on the main biosynthetic pathway to gibberellins, which are important plant hormones.[9][10] A secondary effect arising from the inhibition of ent-kaurene oxidase is that its precursor, geranylgeranyl pyrophosphate accumulates in the plant and some of this is diverted into additional production of the phytol group of chlorophyll and the hormone abscisic acid. The latter is responsible for controlling transpiration of water through the leaves and hence PBZ treatment can lead to better tolerance of drought conditions.[11] The (2R,3R) isomer is a better fit to the active site of the fungal cytochrome P450 14α-demethylase. This inhibits the conversion of lanosterol to ergosterol, a component of the fungal cell membrane, which is lethal for many species.[5] Many other azole derivatives including propiconazole and tebuconazole show this type of activity, so the main commercial opportunity for paclobutrazol was as a plant growth retardant and it was first marketed by ICI in 1985 under the trade names Bonzi, Clipper, Cultar and Parlay.[1][7]
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