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  • Опубліковано 28 січ 2025

КОМЕНТАРІ • 193

  • @AppliedScience
    @AppliedScience Рік тому +101

    I never knew Agilent made Raman spectrometers, and then your comment at the end about civilian restrictions explained why they might be rare ;) Really impressive bit of kit, and great explanation! I wonder about substances dissolved in a solvent - same signature?

    • @jafinch78
      @jafinch78 Рік тому +3

      Me neither, I last left off working on the Ahura Truscan system development and validation for RM testing and some other interesting spectrometers. Unfortunately, the RAMAN spectrometer were more destructive compared to like the ATR FTIR or FTNIR systems I preferred where both need to use more advanced software, especially the later. So that system went forward more with the nutriceutical site. Seems like a different life at times and man do those that have the systems probably not use em from what I found in the service roles lack of forensics other than to rob in the jurisdictions I've been adversely impacted by and I'm guessing some get super pissed knowing how easy stuff can be detected. Though like the related NIST standards, technically they're used in space and even publicly drones have hyperspectral imaging so like spectra of each pixel, i.e. voxels. Didn't know Agilent made spectrometers at all either.

    • @samthenerf
      @samthenerf Рік тому +9

      Agilent acquired Cobalt Light Systems in 2017 the Resolve seems to have been developed before the acquisition.

    • @Thesignalpath
      @Thesignalpath  Рік тому +32

      I tried various solvents. The result was a combined effect of the two substances. Unless of course a chemical reaction took place in which the new signature would be the result of the reaction plus any leftover unreacted compounds.

  • @trevorjayman4364
    @trevorjayman4364 Рік тому +48

    I am more amazed that this guy has so much knowledge about so many things... Agilent got super lucky to have him review their product...

    • @loueckert4970
      @loueckert4970 Рік тому +1

      I agree--amazing product review. Phew

  • @rex-up9ln
    @rex-up9ln Рік тому +7

    Chemist here, who's also into electronics. Raman spectroscopy is really a bit like magic. I'm from Calcutta, and have visited Raman's place of work. What he and his students achieved without the help of modern instruments is really amazing. I have worked with benchtop ramans, but a handheld version is super cool. Great video as always

  • @HuygensOptics
    @HuygensOptics Рік тому +10

    Very well made video, I watched it from beginning to end! When I was a student I did stimulated Raman scattering in D2O using picosecond laser pulses. You could actually get quite high intensity Raman lines, that could even be used to do time-resolved spectroscopy.

  • @MIsam-fv9kb
    @MIsam-fv9kb Рік тому +20

    Wow amazing the quality of content in this channel is just unmatched.

  • @lbgstzockt8493
    @lbgstzockt8493 Рік тому +35

    If it is at all possible you should definitely do a video on your time at Bell Labs, I bet many people would love some insight into that mysterious organisation.

  • @teslastellar
    @teslastellar Рік тому +37

    What an amazing instrument. Thank you for explaining how it works 🙂

  • @JonPMeyer
    @JonPMeyer Рік тому +6

    Awesome video! That product is basically a large chunk of 20th century physics condensed via 21st century technology into a massively useful device. Your thorough but brief description of the underlying physics was very understandable. Thank you!

  • @oldblokeh
    @oldblokeh Рік тому +53

    Spatially offset Raman spectroscopy was invented at the Rutherford Appleton Laboratory in Harwell, UK around 2005. They then spun off a company which was acquired by Agilent in 2017. New SORS capabilities are still being developed at the (now) Agilent facility in Harwell. So, it's British. And, no, it doesn't leak oil.

    • @mikeissweet
      @mikeissweet Рік тому +2

      Britain and India have some history, I understand?

  • @fredflickinger643
    @fredflickinger643 Рік тому +8

    It all started with Raman and his prisms, now thankfully for Shahriar, Agilent, Dr. Stokes and Dr. Blanco we are most appreciative to see Raman's work so well integrated and fine tuned into a portable package that no doubt gives some the ability to quickly assess potentially dangerous situations. I find this to be one of the better adaptations of a sound theory.

  • @mikesradiorepair
    @mikesradiorepair Рік тому +6

    LOL, to be honest I thought this was a spoof like the Turbo Encabulator for the first few seconds but quickly realized it was real. Amazing instrument and thanks for the fantastic review.

  • @purerhodium
    @purerhodium Рік тому +10

    Finally a type of instrument I have actually used before. If you ever somehow find your hands on a mass spectrometer (either quadrupole or orbitrap) or an NMR spectrometer, I think it would be really fun for you to do a video on them. RF circuits are at the heart of those instruments and I'd love to see what kind of insights you can give into their workings.

    • @andymouse
      @andymouse Рік тому +1

      Same here, I worked for VG Scientific in the UK and was involved with Mass Spectroscopy, SIMS, Tof SIMS (Secondary Ion Mass Spectroscopy and the Time Of Flight stuff) back when this device really was SCFI !

  • @TheBananaPlug
    @TheBananaPlug Рік тому +7

    Excellent video, many thanks for bringing this technology to a wider audience, and of course thanks to the Agilent team for getting it into your hands. Having studied Raman spectroscopy at school many years ago for my Chemistry Degree and working with large benchtop instruments, its just amazing to see so much analytical power in such a small footprint device.

  • @gregorymccoy6797
    @gregorymccoy6797 Рік тому +4

    Well worth my time!!! Amazing. Thank you to the scientists who supplied the device,too.

  • @McTroyd
    @McTroyd Рік тому +2

    Really cool find, Shahriar! I've long known that spectrometers exist, but never anything with that much precision in a handheld unit. Amazing.

  • @arashghasemi
    @arashghasemi Рік тому +9

    When showed up in the UA-cam notification bar, I thought it was noodle maker or something of that business. What an amazing technology it is indeed

  • @Afrotechmods
    @Afrotechmods Рік тому +2

    I liked the mixer analogy!

  • @AI7KTD
    @AI7KTD Рік тому +4

    Easily one of my favorite TSP videos

  • @tfinmoraes
    @tfinmoraes Рік тому +5

    That was a delight! Great explanation, really well thought knowledge cadence! Thank you Shahriar. Hope you enjoy it, well deserved! Also extending to Dr. Stokes and Dr Blanco for making this happen.

  • @ForgottenLore
    @ForgottenLore Рік тому +1

    Easily Nobel prize worthy, such an interesting phenomenon made yet more impressive by such a well designed implementation of it.

  • @jhonbus
    @jhonbus Рік тому +3

    That spatial offsetting technique is incredibly cool! I'm absolutely fascinated by sensor technology of all kinds, and all the tricky tricks like this are really what excites me. I should definitely try to get a job in this field.

  • @klassichd10
    @klassichd10 Рік тому +4

    Again, another great YT highlight! Thanks a lot for this really great episode. A very impressive instrument too. Thanks for the lot of work, you are doing and sharing the results with us.

  • @gsuberland
    @gsuberland Рік тому +1

    Great video! This sent me down a rabbithole of trying to figure out how the Planck relation could be reconciled with the idea that zero-bandwidth electromagnetic waves are impossible. That led me to the time-energy uncertainty relation, which led me back to natural line width in spectroscopy. Always fun when that happens!

  • @lmamakos
    @lmamakos Рік тому +6

    That's AMAZING! A thing that I didn't even know existed does, which is remarkable and then the amazing feats of physics and signal processing... essentially all reduced to one EASY BUTTON. Wow.
    On a related topic, it would be really interesting to take one aspect of this and run with it.. please do a video on Raman amplifiers. Or as I was told, the reason why it's not always safe to look down the receive side of the fiber pair. All I knew before is that there's a high power laser pump source, some chunk of fiber that's apparently doped with magic and then more photons come out than you started with. I think I have hint now of what might be going on, thanks to this video.

  • @Hasitier
    @Hasitier Рік тому +1

    Fascinating instrument. I was not aware that such a thing exists.

  • @ypx5ub
    @ypx5ub Рік тому +3

    Wow! Thanks to the people who made this video possible!

  • @AmirASD
    @AmirASD Рік тому +4

    Damet garm. Great job. I loved seeing the entire video and how it works, and when it doesn't work. Also thanks to, Dr Robert Stokes and Dr Anna Blanco for making this possible. The library of signatures available in there is fantastic.

  • @geekdaniel7595
    @geekdaniel7595 Рік тому +1

    Just... wow. I learned so much about a field I knew nothing about. Thank you!

  • @TerryLawrence001
    @TerryLawrence001 Рік тому +4

    Finally! We can find out what's inside those little packets that come with noodles.

  • @mikegLXIVMM
    @mikegLXIVMM Рік тому +1

    This has to be the Top Raman spectrometer I've seen! 🙂

  • @Kapitaen_Flauschbart
    @Kapitaen_Flauschbart Рік тому +2

    That was incredible! Many thanks for all the effort.

  • @BM-jy6cb
    @BM-jy6cb Рік тому

    That is super impressive and interesting. Thank you so much for making this and other videos - they are real educational eye openers. There are some extremely clever people in this world. I'm unfortunately not one of them!

  • @PapasDino
    @PapasDino Рік тому +4

    What a wonderful informative review, thank you so much Shariar!

  • @HisSadShadow
    @HisSadShadow Рік тому +3

    Bravo ! You just melted my brain at 4 am and made me crave some ramen.

  • @djohnsto2
    @djohnsto2 Рік тому

    This is super cool. Some day the leading smartphone makers will have these on their flagship phones.

  • @davidfranzkoch9789
    @davidfranzkoch9789 Рік тому +1

    This is so cool. That instrument really feels like magic. But after watching this I have a rough idea on how it works. Thanks!

  • @deadbugengineering3330
    @deadbugengineering3330 Рік тому +3

    That joke near the end caught me a bit off-guard. 😁 Thanks for giving us another high quality educational video!

  • @Gigabecquerel
    @Gigabecquerel Рік тому +3

    Amazing video!
    I love all the in-depth explanations and tangents, well done!

  • @0xbenedikt
    @0xbenedikt Рік тому +1

    Thank you for making this interesting video. I did not know this existed!

  • @originaltonywilk
    @originaltonywilk Рік тому +2

    Outstanding application of principles, kinda obvious when you explain it :)

  • @cedivad
    @cedivad Рік тому +9

    TPS is finally hacking the algorithm:
    1) First time I see him do thumbnail design.
    2) Hook and sink in the first 3 minutes of the video rather than dropping the audience to technical jargon.
    Love you all the same, Shahriar 🙂

  • @Nik930714
    @Nik930714 Рік тому +2

    That is a great video. A bit different to the normal stuff you cover, but very interesting indeed.
    Video drinking game - drink every time Shahriar mentions a Nobel price from his place of employment.

  • @arinascimento547
    @arinascimento547 Рік тому +3

    Fantastic! It seems like science fiction to me, even you showing and describing how it works!

  • @rolfdieterklein
    @rolfdieterklein Рік тому +5

    Wonderful video, excellent. I also work with small spectrometers, and I know that raman is a huge challenge. I also used a effect which is called two photon absorptions you mentioned in the video, for example with lanthanoids, So a IR source point to the substance and you get back twice the frequency, which is used for forensic identification of objects (you add the substance for identification...) In this case its easy to filter out the laser, were as with Raman this is really a challenge.

  • @jessicav2031
    @jessicav2031 Рік тому +11

    Very interesting. I'm guessing a thin aluminization layer like with typical moisture (or static shielding) packaging is enough to block detection? I'd be curious to try it on containers with different levels of metalization, like a partly transparent static shielding bag. Surely potato chips are out 😆

    • @jhonbus
      @jhonbus Рік тому +1

      Good question. I suspect while a thin layer may not block the laser radiation it'll probably block the Raman emission from being detected.

  • @debasishtahbildar9603
    @debasishtahbildar9603 Рік тому +4

    What a piece of tech... This is mind boggling 😊

  • @shazam6274
    @shazam6274 Рік тому

    Absolutely Amazing! Thanks for the deep dive tutorial on this subject and experiments with the instrument. In addition to all the rare optical, laser, detector and assorted circuitry in this compact portable instrument, you forgot to mention that it is made of un-obtanium and the cost of un-affordium! Seriously though, ballpark prices, or price ranges, of the items you discuss would be very helpful. After all, we can all admire the engineering and design of Koenigsegg cars, but know that lusting after one without a million dollars handy is a fantasy. The Agilent Resolve Handheld Raman Analyzer featured here is unique in its compactness and ruggedness and may be very useful to many people in many industries, most viewers will not find out, especially since there is no pricing listed by Agilent, or anyone else. Best I can conclude is that 1/2 of the equipment behind you cost multiples of this device, making it in the $20 ~ $50 thousand dollar range. Perhaps someone from Agilent can research the process of selling, perhaps to the nano and pico particle levels, to discover that, whether it is this device or a potato, one of the key ingredients needed for a sales transaction is the price!

  • @glasslinger
    @glasslinger Рік тому +1

    Excellent video! I was kind of wondering how you got such an expensive instrument! (none on ebay!) Does the instrument work on food, like an apple to detect insecticides, or on processed food to detect what chemicals are in it?

  • @jafinch78
    @jafinch78 Рік тому +2

    Really awesome presentation and really neat system. I worked with the Ahura Truscan systems holistically and is interesting having the software experience as well since that training and modeling really makes a significant difference and is amazing how magical like seems as well. Amazing the advances in the MEMS and other related systems advances. Neat how some have even DIY made RAMAN spectrometers.

    • @jafinch78
      @jafinch78 Рік тому

      Interesting, the cryocooling or cooling capabilities that somewhat seem like advances in vacuum tube tech sort of. HHHmmm, I've wondered about that graph noting the developments over time and what the future might look like? Not only in larger sizes, smaller sizes as well.

    • @jafinch78
      @jafinch78 Рік тому +2

      The Michelson Interferometer FTNIR I implemented at Perrigo was originally developed for primarily testing pseudoephedrine since was needing to be controlled as in the Methamphetamine Awareness Training we were told drums used to be stolen at timea and the lab even would throw out larger sample bags full of for each lot and batch prior to implementing more security controls. Guessing still gets stolen anyways. Crazy, is the psuedo is the wrong isomer to make the CNS stimulant. Great vasoconstrictor though and dangerous to be used for stimulation. Made me feel weird like my back tingly. Anyways, memory lane. Reminds me of investigational new drugs and approved along with days I wanted to scan mixtures and whatever unknowns that might be found on site. Though that was FTNIR mainly, though I'm sure to an extent if I had at my site the RAMAN systems implemented, I'd be that obsessive. The FT microscopy and hyperspectral imaging were my dream machine systems as well for investigations.

    • @jafinch78
      @jafinch78 Рік тому +2

      Wondering in regards to applications, the advances in medical diagnostics testing like for glucose monitoring, imaging and like at Tech I was inspired to work under the late Dr. Leifer using Mössbauer spectroscopy for diagnostics testing. At the time, as I still am thinking, the rotational and vibrational molecular energies had-have more my attention, since talk about controversial not well disclosed spectroscopic methods. The orgo lab had the microwave, albeit not the tuneable one I envisioned to use, so I was compelled to research with. 🙂

  • @dwagner6
    @dwagner6 Рік тому +6

    I’ve gotta say…I’m gonna need a tear down. Will Agilent send you anything to show off? So cool. Almost making me consider optoelectronics for my masters.

  • @basspig
    @basspig Рік тому +2

    I remember working with helium cadmium lasers back at intek Corporation in 1978. A fascinating ultraviolet laser. We used the light sources for inspecting certain types of photographic film.

  • @andymouse
    @andymouse Рік тому +2

    Awesome instrument and wonderfully explained. You have qualitative info can there be quantitative info too ?...cheers

  • @nerdtalker2
    @nerdtalker2 Рік тому +1

    This is easily the best video on youtube and the ultimate representation of the saying "the future is here, it just isn't evenly distributed yet". I wish Agilent would sell the general public this instrument. I would buy one in an instant.

  • @martylawson1638
    @martylawson1638 Рік тому

    Small correction on that laser pointer crystal. It's way more than just a doubling crystal. It's usually a stack of a Nd:YAG crystal with a non-linear crystal that has the ends coated so one end reflects 800nm and 1064nm while the other end reflects 532nm and 1064nm. The ends of the crystal are also flat with the laser cavity stabilized by the pump laser heating the cavity and curving the ends of the crystal. A neat side effect of all this is that most green laser pointers are single-frequency single-mode lasers. If you can thermally stabilize it well enough, it'd make a great source for holography or conventional spectroscopy. (they'll happily excite individual absorption lines of Iodine vapor)

  • @noalear
    @noalear Рік тому

    Oh wow, I want one of these! I cant wait to see how small they'll eventually get this.

  • @nated1971
    @nated1971 Рік тому

    this looks a lot like the old Ahura First Defender. We used it 20 years ago for identifying unknown materials. Looks like Agilent has taking it to the next level

  • @YDKMPablo
    @YDKMPablo 11 місяців тому

    Amazing explanation about many physics phenomena and their correlation.
    Mind***k video.
    Congrats.

  • @travisthesutherland
    @travisthesutherland Рік тому +1

    Always incredible

  • @svenhoek
    @svenhoek Рік тому +2

    Really cool tech! Excellent video!

  • @c4t4l4n4
    @c4t4l4n4 Рік тому +6

    Wonderful episode! I was able to wrap my head around this technology and understand how it works (or at least at the fundamental level). It also demystifies the workings at custom/ border checkpoints. Next time I have to check my baggage, I'll have an idea as to how they check. Obviously there will additional instrumentation to augment devices like these.
    It's like a dog in a box, lol. 😀

  • @supernumex
    @supernumex Рік тому +1

    Very cool! there are hand held instruments for determining metal alloys as well. I believe using xrays?

  • @mohamedlanjri
    @mohamedlanjri Рік тому +2

    Awesome video! Will be great if you can make some measurements of electronics related subtances, like semiconductor's composition (SiGE, GaAs, InP, etc...)

  • @antoineroquentin2297
    @antoineroquentin2297 Рік тому +1

    Very interesting. Could they use time-of-flight to determine what's inside of a package?
    And what does it show if you hold it against the body?

  • @trickyrat483
    @trickyrat483 Рік тому

    Great stuff. Big thanks to all involved. Was rivetted from start to finish.
    Although you forgot to mention how much it costs. :)

  • @aeloolindowy
    @aeloolindowy Рік тому +2

    For the first measurement, how did the spectrometer "know" whether you wanted to measure envelope material or bottle material or bottle contents or second layer of bottle material or second layer of envelope or your hand or the wall? They were all in front of the spectrometer.

  • @ikocheratcr
    @ikocheratcr Рік тому +1

    When two substances are detected (isopropil + acetone for instance), can the device provide the ratio of the two?

  • @uploadJ
    @uploadJ Рік тому +2

    Say - Now I understand how Raman spectroscopy was one of the trusted analytical techniques used to very the transition of Hydrogen into Hydrino too.

  • @PelDaddy
    @PelDaddy Рік тому +1

    Thanks. That is amazing, and you did an excellent job explaining it.

  • @JJisMe1972
    @JJisMe1972 Рік тому +15

    Now we just need Agilent to make a replicator.

  • @DEADB33F
    @DEADB33F Рік тому +1

    Does it have a mode which can identify different flavours or Ramen?

  • @jessiepooch
    @jessiepooch Рік тому

    Wonderful stuff,thanks!

  • @stevenbacon3878
    @stevenbacon3878 Рік тому +1

    Great video! Awesome tool too.

  • @blacklion79
    @blacklion79 Рік тому +1

    I wonder, could it distinguish different grades of steels and other ferrous alloys?
    I know, that handheld XFR devices are used for this.

  • @lenovotab2847
    @lenovotab2847 Рік тому

    Should it recognize the cotton from the q tip ?

  • @____________________________.x

    That device is way more sensitive that I’d have believed possible

  • @raymiller5738
    @raymiller5738 Рік тому +2

    Well done, while technical your explanations are excellent keep up the good work, I had no idea before how it was possible to determine what was within a container. Magic demisstified successfully, now the device just needs to go on a diet to the make it the same size as a real triquarter.

  • @____________________________.x

    I’d imagine every crime scene cop would love one of these, they would never know what they would be walking into otherwise

  • @dand5593
    @dand5593 Рік тому

    2:20 on the scree is clear - scan 26-, how did you done 'undreds?

    • @Thesignalpath
      @Thesignalpath  Рік тому +1

      Because this is a new unit and I have two of them in my lab.

  • @donaldbray2147
    @donaldbray2147 Рік тому

    Were there any features or analytes that Agilent locked out or requested no comment? Maybe unanswerable question. I've worked on development of competitor's earlier generation instrument but it had other capabilities including gasses and radionuclide detection, and other features that at RFP review seemed technologically extremely challenging. Handheld devices like this for some years now also feature GPS, cameras, Irig, satellite link.
    As Shahriar alludes near end, these devices aren't usually available to civilians. Not because they include classified technologies but because they are developed under contract to government agency, in the US now its usually Homeland Defense. My project, they wrote the RFP, professional and clear specifications, funded the development, and it was our understanding it was in response to interdiction agencies technical, safety, and prosecution challenges.

  • @modrobert
    @modrobert Рік тому

    Very interesting. Is this instrument IoT, as in "phone home" regarding the samples tested?

  • @leocelente
    @leocelente Рік тому +1

    Really cool video!

  • @ToniT800
    @ToniT800 Рік тому

    Hm, when you used Q-tip to detect Glycerin, why it didnt detect wool or whatever the Qtip is made of?

    • @Thesignalpath
      @Thesignalpath  Рік тому +2

      It is also reported down the list of other compounds, I just didn't show it.

  • @tinarenarde
    @tinarenarde Рік тому +3

    The answer to the obvious "how much" / price question seems to be... Approximately $65,000 which is about what I expected.

  • @robertfenney
    @robertfenney Рік тому +1

    Facinating!

  • @mjmeans7983
    @mjmeans7983 Рік тому

    Can it be used without any internet connection? i.e. deep underground in a mine? I'm curious if ot can identify minerals.

  • @madmax2069
    @madmax2069 Рік тому +1

    I've always been fascinated by Spectrometers in how they operate. It makes me want to buy one, but they're far too expensive for me to buy.

  • @AlexTaradov
    @AlexTaradov Рік тому +5

    Any idea how much this costs?

    • @Conquest_of_Paradise
      @Conquest_of_Paradise Рік тому +1

      Yes also interested in the retail cost of one of these units.

    • @Dextermorga
      @Dextermorga Рік тому +1

      My guess price of a new car

    • @Carsenator
      @Carsenator Рік тому +2

      According to a quick google search it is $65.000,-

  • @Yorumcu63
    @Yorumcu63 Рік тому

    Great Product
    What is price of this Analayser?

  • @nightcrawler8226
    @nightcrawler8226 10 місяців тому +1

    Man. He speaks like some teachers. And I imagine him talking to Geordi La Forge and Data in the Holodeck!
    Man! I don't know a looot!
    Thank you anyway,
    Knowledge Master!
    😅😅 😮😮😮

  • @anonymousarmadillo6589
    @anonymousarmadillo6589 Рік тому +1

    Does the instrument run windows?

  • @ralfschooneveld3186
    @ralfschooneveld3186 11 місяців тому +1

    33:03 how much does a unit like this cost?

  • @jamesfrancom8100
    @jamesfrancom8100 Рік тому

    PUCHHH! Mind blown!

  • @geemcd
    @geemcd Рік тому +1

    Crazy parties round Signal Path garage ❤

  • @gatoalfa7
    @gatoalfa7 Рік тому +2

    I glad you didn’t mix the potassium permanganate at the beginning of the video and the glycerin at the end.

  • @juergenherrmann949
    @juergenherrmann949 Рік тому +1

    TEARDOWN! :)

  • @artyzinn7725
    @artyzinn7725 Рік тому +2

    These scanners would be great in searching for counterfeit, even just as a preliminary screen, since the materials signatures of legit devices would be different from those made elsewhere or altered, such as drugs, electrical components, textiles, etc.,

  • @janbottorff4642
    @janbottorff4642 Рік тому +1

    That would be a great cell phone feature!

  • @enermaxstephens1051
    @enermaxstephens1051 9 місяців тому

    What happens if you put your hand on top of it? Does the screen say human blood? Also how much does it cost?

  • @florianhofmann7553
    @florianhofmann7553 Рік тому +5

    Damn can't you prompt a warning message to put on our safety glasses before shining a laser into the camera. Luckily I do wear my sunglasses at night.

    • @hexwell
      @hexwell Рік тому

      NorthridgeFix moment 😂

  • @EgonSorensen
    @EgonSorensen Рік тому +1

    Now I'm *really* looking forward to the episode where you take a closer look at a real-life replicator, capable of replicating this device :ø)