USMLE STEP 1: PHARMACOLOGY (VIDEO 6) - PHARMACODYNAMICS
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- Опубліковано 24 сер 2024
- ESSENTIAL MATERIALS
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USMLE STEP 1: PHARMACOLOGY (VIDEO 6) - PHARMACODYNAMICS. This video reviews the beginning concepts of Pharmacodynamics. Questions should be at the level you will see on STEP 1. Hope you like the video...
you are gold doctor , i used your videos for biostat and i master it , now i'm using the pharamcology videos as a recap and i'm mastering pharamcology too , i can't thank you enough , your efforts is very much appreciated .
Thank you Ali for taking time to comment.
I get a dopamine hit every time I watch your videos 😃
Thank you Sangay,... Keep me posted on your STEP 1 progress...
One of the best videos I have seen for Gq pathway. It finally makes sense, on the day right before the exam. THANK YOU Dr. Neil!
PERFECT. Go CRUSH the Exam...!!!
Repetition makes me to have deep roots to these concepts,thank you!
Repetition is the key... Thank you for taking time to comment.
@@RandyNeilMD thanks for the great work
Doc you are amazing if I just had a teacher like you during med school it would have been way easier. Thank you for making these videos
You are most welcome. Thank you for the comment.
taking step 1 in a few days and your videos have made me so much more confident in my abilities- thank you
Thank you Hannah… very kind of you. Study hard. Keep me posted on your progress.
Hi Dr. Neil, I just finished watching all your Pharm videos in this playlist, thank you so much for making this for us, I feel much more prepared after going through them. I was wondering if there is a video released on the agonist/antagonist, etc topics. I think you mentioned in your video there was one coming but don't know if I cant find it on your channel. thank you!!
Not sure if I made that... I'll get back into making more videos soon... I'll make sure to add.
@@RandyNeilMD yes please,do add them kindly,,very much needed
I’m at minute 16 of this AWESOME video , and I went to the FA book to sesrch for that little arrow showing the back door going up of the increase of intracellular Ca, from IP3 to Protein Kinase C,. Another awesome well explained, detailed video, congratulations Dr. 👍👍👍 God bless.
Daniel, Yeah, I never knew it was relevant until I started seeing questions... Now that you have it...you won't forget.
Step 1 in 29days, and i come across these golden general pharma videos nowww!
Better late than never i guess
Thank you so much Dr. Neil!
PERFECT Timing!!
Best explanation I have ever seen on G proteins. Awesome stuff, thank you
This brilliant approach is the only way....THE ONLY WAY you should approach these questions. Thank Dr. Neil!
Thank you got the kind comment.
Amazing approach, thank you for your explanations and videos
Glad it was helpful
why would ANYONE DISLIKE these videos?!!! If everything was taught by dr neil then i think anyone that follows him would get 90% on the steps. Hs is THAT GOOD!!!
thank you dr neil for taking the time out of your busy schedule to provide these for us.
Aww... Thank you for such a kind comment.
You are an angel Dr. Neil!!! So thankful to God for sending you to us examinees!
Thank you for kind words!
Your videos have been so helpful in my preparation for Step 1, thank you for the hard work you put into these videos to help us succeed!!
Payal, Thank you for taking the time to comment. I am glad videos are helpful for you.
What a well explained and helpful video l. , As always ,practical and easy to understand! When I pass , God willing, my Step 1 , a significant part will be due to these great videos. Keep them coming Dr. McNeil, you do great work 👍
Thank you Daniel
Dr Neil is a born teacher who simplifies difficult concepts..Thanks Sir
Thank you Stephen
Thank you so much!!! I finally understood the basics of pharmacology thanks to you! Your lectures are GOLDEN
Thank you Arailym for taking time to comment.
Thank you so much;your videos are really great & method of teaching is so good.( I also remember like Gi=(MAD)2,guys to Inhibit.Gq=$131(M1,3&a1)Rest is Gs..(ie;B1,B2,D1=121).🙏🏽🙏🏽🙏🏽🙏🏽
Thank you for sharing... It definitely helps and reinforces. Thank you Tara.
Thank you so much Dr. Neil, I have watched so many of your videos. My test is in a little less than 2 weeks!!!
Ana, Stay confident!!
Forget to mention loved your method of starting backward then cover big pictures soo brilliant!!! thank u again
Glad it was helpful.
Your way of teaching is top notch!!!! The way you simplify these pathways is EVERYTHING! Please do more pharm, biochem, and all systems physiology videos!!
thank u so much dr neil. wonderful work.
You are very welcome.
Thank u so so so much Dr Randy
Hafsa, You are most welcome. Keep studying HARD!!
Been struggling with this. Finally got it!!! Thanks Dr. Neil. FA needs to recommend your videos!!!
Thank you Joseph.
AMAZING very helpful playlist. You are amazing, Dr Neil. Thank you so much!
Thank you for the kind words!
Superb
Ortho, Thank you
"Thank you" is an understatement. God bless you dr!
absolute legend
humbled.
And now finally these G protein makes some sense to me 😅 thanks alot Dr Neil
Dr. A, Glad it was helpful. Thank you for commenting.
amazing
👍🏻
Can't thank you enough! Simple and clear explanation!
You are most welcome.
Thank you so much for all the effort you've been putting into this! very much so appreciated!
You are most welcome Zeynep
The presentation skills are amazing
Thank you Omar
Thank you so much Dr. Randy. I really appreciate your efforts and time that you put to come up with these fascinating videos. We are waiting for your new videos!!!!
Ibrahim, Thank you for taking the time to comment. Glad the videos are helpful.
Exam is day after tomorrow and watched all the playlist 😅, very helpful thanks 😊
Adnan, I hope this reaches you before your exam. STAY CONFIDENT, STAY FOCUSED... GO ON SMALL WINNING STREAKS. It's "SHOW TIME"... Not a time to fear, but a time to FINALLY SHOWCASE YOUR SKILLS.
This video made things soo much simpler! Thank you Dr.Randy.Could you please discuss about the various autonomic drugs?
Pranuthi, Thank you for taking the tie to comment. Let me see what I can find...
I have no words to say to express how grateful i am to you, these type of questions for me was so hard that i accepted the idea that i will just get them wrong because i tried so hard to understand it with no results, then i watch this video and you make it so easy and simple that makes me doubt my brain capability of understanding stuff :D.
thank you so much Doctor and i will be forever grateful to everything you taught and will teach me, i really wish you the best!.
Hossam, Thank you for taking the time to write such a nice comment. It's all about helping the next person in line...
absolutely loved the pharmacology series videos! thank you Dr.Neil for the amazing content and let the good stuff keep coming :)
Mehak, Glad it was helpful. Thank you for taking time to comment.
I am a pharmacist, but man I love your videos, please do for step 2 CK
Thank you for the comment and glad it has been helpful.
today learnt very basic ad often missed concepts. thank u sir.
Moseeb, You are most welcome. Thank you for taking time to comment.
very helpful!! thought I was solid on GPCR until I watched these and could barely answer the questions. Thank you for saving me!!!!!
Excellent videos, thank you for all your hard work!
Mary, Thank you for the comment. Glad it was helpful.
Was desperately waiting plz dnt stop making them.
Arooj, I appreciate the feedback... As long as people watch and tell me it's helpful...I'll continue.
Thank you very much for taking time to share your knowledge about these topics, Dr. I've watched all your Pharma videos and made notes on it! It really helped me understand the concepts in a simplified manner. THANK YOU! :)
Mai, I'm glad the videos are helpful. Thank you for taking time to comment.
you are amazing, thank you
Thank you.
Thank you Dr Neil for such an amazing video series!
You are most welcome.
you make it sound so easy, sir...😀
I struggled more than anyone will ever know...
I was your student at Baltimore site. studying for step 1, I am really using it videos as a prep material. Thank you for doing this. 👍🏽
thank you for your efforts sir
Not a problem.
Your basic pharm videos are life saver , thanks a ton :D
Rishi, Thank you for the comment. Glad it was helpful.
Thank you very much Dr. 👏👏👏👏👏 Respect
Alok, You are very welcome.
THANK YOU DR. NEIL!!!!
You are most welcome
Amazing work
Thank you.
You are most welcome.
I have my exam in 2 days ... I would just watch your videos and Dr Hussain Sattar's 3 chapters :D
Thank you to clear the concepts Dr Neil.
Sam, Glad it was helpful. Thank you for taking time to comment.
Respect..doctor
Thank you Mohammed.
Really very very helpful 😍 thank you so much Dr.Randy 💕
Nagwan, You are most welcome.
i'm soo much inlove with your videos.. thank you so much
Thank you Nana, Glad they are helpful.
You are awwwwwsome Doctor… m a lot lot impressed..
Please attach drug n receptor video with reply..
thanks
Will try
im really so surprised how helpful u r yet so underrated !
u helped alot !!
Iyab, Thank you for the feedback.
you are PHENOMENAL THANK YOU
Thank you Mary.
Thank you Randy..
You are most welcome.
Plz upload more videos, you are awesome 👌, and honestly you ll get the result 👍.
Musawair, I always appreciate you taking the time to comment. Much appreciated.
Tks a lot. You’re making it easy memories
Ryan, You are most welcome.
Thank you so much sir for your great content and I would also like to thanks for your such a amazing explaining skills.
Actually I'm waiting for your next more pharmacology videos for many days.i kindly request you to post more next videos on pharmacology please
Atharva, I may circle back around to PHARM... It seemed like the topic was losing interest so I went to the next...
No sir ,many more students are waiting for your next pharma videos, you know I'm suggesting your video to my juniors and freinds they are very happy after watching your videos they thanks me to suggest your videos.
Thank you so much for your videos; they’ve been so helpful and easy to understand.
Please have you done any video on enzyme kinetics like as Michaelis-Menten kinetics, effects of enzyme inhibition and receptor binding?
Watched all pharm vids , haven’t seen such a simplified explanation of concept , thanks a ton for it , please make a video covering Michaelis Mentin kinetics , Lineweavwr burk plots like comp and non competitive inhibitors
Ahtesham, You are putting me to work... :/
Randy Neil, MD Lol , not my fault , stop making such super short and immensely easy conceptual videos and there won’t be any demands further 😀
Yes Dr. Neil, please cover these topics and the remaining from FA General Pharmacology chapter. Eagerly waiting.
Yes Dr Neil,please cover the above topics.
i love your style and really would love to watch you all the day ,DR Neil ... really thank you for your appreciated efforts.
Thank you for the nice comment. KEEP STUDYING HARD!!
How do you know if your smart?
When information like this is presented to you and (assuming no or limit baseline knowledge) and you process the information at deep levels, and more importantly recall when presented with the same or similar information and are able to interpret and problem solve. Memorizing, well has a wow factor but unless you can effectively solve problems, short term memory alone won’t get you very far
It's all a bout the repetition... The ability to recall may make you a good test taker for STANDARD EXAMS... but you got to have some "problem solving" skills to get through the STEP Exams... My goal to to try and simplify as much as I can and make sure you don't see something for the first time on the exam... Hopefully, you can make your mistakes with me, not on the exam.
thanks a lot for posting these awesome videos.They are very helpful and i am learning many new things..actually,my husband is a non medico but even he is able to answer the questions after listening to your videos..haha
Very nice. Thank you for commenting.
Hey doc, thanks for teaching.
But I have doubt @16:07 you mentioned Protein Kinase A increases Calcium but, you choose IP3, which also increases the calcium.
So how did we eliminate Protein Kinase A?
Ps: First aid 2020 mentions both protein Kinase A and IP 3 increases Calcium.
I'll have to go back and look at it... Can't recall without looking. Appreciate the feedback.
@@RandyNeilMD from what I have learned from Dr Najeeb is that Pk A phosphorylates ca channels leading to ca influx
Whereas IP3 is the only one here which directly acts on ER releasing ca intracellularly
Hello Dr. Neil. Just finished your Pharmacology series And I've got to say that Your videos are Golden... If You could also make a series on Acid base balance then it would be a Great help. Thank you!!!
Thank you for the comment. I thought I did ACID-BASE video... I could be wrong, but I thought I did.
please make more videos on efficacy and potency
Yes, that would be a good topic for questions.
I don't know if i'm missing something, but following your pathways, regarding the first question...how do you decide between D.) IP3 or B.) Protein Kinase A, as they are both "directly responsible for release of intracellular Ca2+." The question does not specify WHERE in the body this is occurring. Thanks for you videos! Always helpful!
Sir i am loving your videos its very much helpful in making concepts nd you make look like how easy it is what was highly difficult at times so thank you very very much hope to see your more nd more videos
Ali, Thank you. for taking time to comment. Much appreciated.
Thank you so much
You are welcome.
your videos are SO helpful!
Glad they are helpful. Thank you for taking time to comment.
Hi Dr Randy thank you for the free points on the test day.
Chetan, I always appreciate your comments.
As always thanks for sharing, Doc! Regarding intracellular Ca2+ release (1st question.) Why not protein kinase A?
This video is Gold
Best explanations I’ve ever seen! Thank you Dr. Neil.. you’re our hero
May I have the notes?
Thank you so much sir , you've been of immense help. 😁
PERFECT. Music to my ears.
Norepinephrine effect the change by increasing intra cellular calcium.That is a different way to look at it.Thus any of the pathway leading to increase in calcium level could be the answer.
Huge thanks!
Xaaboo, Glad it is helpful
Hello Dr.Neil I have to thank you so much for the amazing videos that you are making… very helpful ,very easy and fun to watch😀 but please upload the notes of the pharma videos to website because they are not there! 😊
Working on it.
Thank you so much ....
Mohammad, You are most welcome.
concepts cleared..thanks a lot doc! :)
Raj, I am glad it was helpful... Keep studying HARD!!
doc you didnt cover that agonist antagonist graphs . waiting for these
Thankyou so much for all your efforts sir it has helped a lot....
it will be great if you could make video on receptor binding , agonist with competitive noncompetitive and partial agonist thing and those graph of fa is so much confusing
I will try and work that topic in... It's a very good topic to know.
Is there a way to remember which drug affects which receptor?
Thanks ♥️ 😊
You are welcome
Your videos have meant more to me than you will ever know! I went on the website and didn't see a Pharm one-page pdf. Also, the Behavioral button is linked to the BIOC pdf. Would you reupload please?
Yes, It's all messed up a bit, but even more difficult to get it changed out...
Thank you doctor. Can I have your notes paper in video ? PDF
aWSOME PERSON HATS OFF
Thank you Sheeba
Thank you so much for your videos Dr. Neil! Greatly appreciated. I just wanted to ask you about the answer about the GPCR pathway (which factor directly activates intracellular Ca?): why couldn't the answer have been "protein kinase A"?. I thought that protein kinase A in the Gs pathway also directly increased intracellular Ca levels or does it not?
hoping for more pharm vids from you please!!!
Stillhere, I'm always trying to see what I can do better...
Amazing... @josumed6
Perfect.
🎉🎉
Thanks again. Waiting for concepts on agonist , inverse agonist, antagonist etc.🙏
Thank you for commenting... Haven't forgotten.
Hi randy.i asked you for making videos on bacterial and viral genetics and you said yes you will.please try to make video on this topic because 5 to 6 questions come from this single topic in every exam.
Ali, I haven't forgotten... Was working on "Communication"... and had technical issues... I haven't forgotten about BIOCHEM.