Fighting Measles-Induced Immune Amnesia! - Microbial Minutes

What happens when memory immune cells forget their memories?
Without memory of past infections, our immune system is less able to fight off pathogens.
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The problem is that sometimes pathogens themselves are responsible for this so-called “immune amnesia.”
Measles virus-an incredibly contagious virus that is currently spreading in the U.S. and other world regions-can trigger immune amnesia.
This makes people with measles vulnerable to secondary infections even after their measles infection has resolved.
To that end, scientists are exploring treatment paradigms to prevent measles-induced immune suppression and mitigate severe infection outcomes.
References:
The Study
Cox, R.M., et al., Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Feb. 8, 2024. Nature Communications. www.nature.com...
Additional Resources
Brennan-Krohn, T. Measles Vaccination and Infection: Questions and Misconceptions. American Society for Microbiology. Feb. 6, 2024. asm.org/Articl...
Centers for Disease Control and Prevention. Measles (Rubeola). Last reviewed: Nov. 2020. www.cdc.gov/me...
Hagen, A. Measles and Immune Amnesia. Feb. 7, 2024. American Society for Microbiology. asm.org/Articl...
Hagen A. and Larkin P. M.K. What You Need to Know About Recent U.S. Measles Cases. Feb. 7, 2024. American Society for Microbiology. asm.org/Articl...
Peart Akindele, N. A., et al. Effect of remdesivir post-exposure prophylaxis and treatment on pathogenesis of measles in rhesus macaques. Scientific Reports, April 20, 2023. www.nature.com...
World Health Organization. A 30-fold rise of measles cases in 2023 in the WHO European Region warrants urgent action. Dec. 14, 2023. www.who.int/eu...
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