Type 2 diabetic here... taking ozempic last 4 months lost 24 lbs and A1c went from 10.4 to 8.6 in 90 days... more to go, at least 20lbs to go also...besides the sometimes overwhelming nausea all's ok!
As a long term type 2 diabetic, Ozempic has been a miracle medication for me. For years I complained that I was always hungry and never felt full. I saw a therapist for years who specialized in over eating and diabetes. Guess what, did not help. Once I started ozempic, I now feel full, and I am not hungry all the time. There is also a genetic component to my diabetes. My grandmother from Finland had Type 2, all of her children developed it and so did her grandchildren. I resent the non diabetes who are using it to lose vanity weight. By the way, my last A1C was 5.7, in the normal range.
You are doing great! However, 5.7 is actually at the bottom end of prediabetic. Excerpt from the CDC website: "A normal A1C level is below 5.7%, a level of 5.7% to 6.4% indicates prediabetes, and a level of 6.5% or more indicates diabetes. Within the 5.7% to 6.4% prediabetes range, the higher your A1C, the greater your risk is for developing type 2 diabetes."
I started on Saxenda, was on that for a year. I've been on Mounjaro now for a year. My A1C is now normal, and I'm down 66 pounds over the 2 years. I utterly love not ever feeling hungry since before, I always felt hungry even after eating a large plate of food. I've moved down to the 7.5 dose for maintenance purposes. All the other drugs in the category are just the GLP-1. Mounjaro also has a GIP added to it which is a good addition. (Glucose-dependent indpsulintropic polypeptide) He talked about the half life. Mounjaro with the GIP increases the half life.
"People taking Ozempic tend to lose weight because they consume fewer calories, not because the drug itself magically burns fat" - Dr. Robert Gabbay, chief scientific and medical officer of the American Diabetes Association
Obesity is also a disease that leads to death. This is great to prevent everything that comes with obesity. One desease isn’t less deserving of a cure than another. Also obesity is the number one health problem in America
Thank you for having a thoughtful and fair minded skeptic on your show. It was so refreshing to have someone who was deeply educated in the topic talk knowledagbly about the issues in such a balanced manner. Too often skeptical perspectives can be so radical that they lose any appeal or crediblity with the audience, and any valuable insight they might have shared is lost because their positions feel too tainted. Dr. Nick Tiller set a new bar in my mind for what a respectable skeptic you can trust really looks like. Thank you for introducing him to us.
I started on Saxenda, was on that for a year. I've been on Mounjaro now for a year. My A1C is now normal, and I'm down 66 pounds over the 2 years. I utterly love not ever feeling hungry since before, I always felt hungry even after eating a large plate of food. I've moved down to the 7.5 dose for maintenance purposes. All the other drugs in the category are just the GLP-1. Mounjaro also has a GIP added to it which is a good addition. (Glucose-dependent indpsulintropic polypeptide) He talked about the half life. Mounjaro with the GIP increases the half life.
Hello Jeff. Does your insurance cover the Mounjaro for continued maintenance purposes? I'm very interested in this as a sort of head start to help me get back into much better shape. But the cost seems prohibitive, if it cannot be prescribed "on label" for continued weight maintenance. I do in fact have very good insurance, but they have denied other "off label" prescriptions for members of my family.
@@scottyplug For the Saxenda, I think I had a discount card since my insurance wasn't covering it. At that time, it was Cigna. While on Mounjaro, I switched jobs and now have Aetna. They didn't cover it either. I used their discount card that made it $25 a month. After about 10 months, I exhausted the full coverage and it went up to just over $500. The next month after that one (last month), I paid $205. The pharmacy said my insurance covered it now as my doctor resubmitted paperwork and prior authorization to Aetna. I guess proof that I needed it and it was working? The one I just picked up was also ran through insurance, and I paid $25 again. If it stays that way, I'm golden!!
It's a wow factor just how funny these guys can make any serious subject but I really appreciate how honest the good Dr. is in his willingness to say what we do not know.!
@cozmo1266 I pay for it privately. I'm not sure it's fda approved for weightloss yet which is what insurance companies would probably want to see before being willing to pay for a prescription
Thanks y’all for taking about this. I take this medicine, at first I didn’t believe it would work. Since i was used to injecting myself twice daily. With Ozemptic I’ve been able to remove insulin all together. It’s really simplified my life.
I’m a type two diabetic and I take zero diabetic medications now. With my doctor’s input I went on the ketogenic diet in 2019 and feel better than I have for years. You can run on ketones for energy instead of glucose. Dropped weight and my appetite control is a result of the ketogenic lifestyle. Make your choice. I did and will continue to do this lifestyle without meds.
Great episode of a great show. However, I was left a little muddy on what Nick is purportedly skeptical about. He said he was skeptical, and that he's a bit back and forth about whether to be skeptical or not. But then for the rest of the show everyone went on to emphasize how Ozempic and Wegovy are so effective. There was some mention of how it had better not have nasty side effects, with Phen Phen and FDA bureaucracy mentioned; and there was some commentary around the lack of availability for people who really need the drug due to celebrity promotion and off-label use. But I didn't hear any skepticism about the drug's efficacy or reasons why we otherwise shouldn't take it. Perhaps I missed that part?
They should have mentioned it but they didn't. Maybe I can save some people a trip to Dr. Google: "The most common Ozempic side effects are nausea, vomiting, diarrhea, abdominal pain and constipation. Serious Ozempic side effects include allergic reactions, changes in vision and pancreatitis ... Ozempic has an FDA boxed warning for the risk of thyroid C-cell tumors 👀 ... In animal studies, Ozempic caused abnormalities in fetuses. 👀 ... Acute gallbladder disease, Acute kidney injury, Allergic reactions, Diabetic retinopathy, Hypoglycemia (when used with insulin or sulfonylurea)... 👀
I used Saxenda for two months but didn’t inject every day. I only injected every 3rd day and that worked for me. I lost 15% of my body weight. During the time I was on it, I chose to adopt healthy eating habits and portion control. One year on and my weight is the same. You do not need to stay on this for the rest of your life unless you chose to go back to the eating habits that made you overweight to start with.
A doctor once told me that losing weight reduces the size of fat cells, but doesn't remove them and that it takes 3+ years for the starved fat cells to start dying and being removed from the body, so to make losing weight last one needs to maintain the low weight for at least 3-4 years after reaching it. If that is the case with fat cells, a weight loss therapy should require both reaching the desired weight and then keeping it for 3-4 years after reaching it. This could be setting a time table for weight loss usage of medicines.
This is good. As a type 2 diabetic, my doctor recently prescribed Ozempic and mentioned the weight-loss aspect as well - but I didn't know how it worked. Considering I'm rather overweight/obese (30+ lbs), this seems like a good solution in addition to the other things I should be doing. Especially as a diabetic, I'm constantly fighting the desire to eat and drink. I think the main kicker is that it might not be covered by my insurance. Also, if Ozempic isn't available, that could be a problem for me. Since I wear a continuous glucose monitor, which does help with knowing what's going on with food and medications.
I am a type II diabetic, since i got pregnant in 2000 and after using 3 different medication and still was not totally controlled. 2 years ago, my endocrinologist and I decided to try Ozempic. It has been a miracle for my diabetes control. Yes, I have lost a lot of weight, around 30 pounds on it, but the way I got there was not fun at all. The side effects were very strong, but because of its amazing effect on my diabetes, I stuck with it. Now though, I'm having to pay through the roof because the pen with the larger dosage is back ordered and have to pay the smaller dosage pen twice a month. I really wish doctors would be more sensitive to those who NEED it before just prescribe it to people that don't need it, but only want to lose some weight. Its always about the money at the end.
I don't have diabetes, but am overweight, and I get liraglutide, which is mostly the same. Luckily doctors here do not give it out that easily, you have to fit certain requirements to be able to start with it. People just can't get it to quickly lose some weight so they can have that slim beach body or fit in their old dress for a wedding in a few weeks. It's only for people who really struggle with their weight.
You are in my definition of "needing" it! I know quite a few persons that asked for it with minimal weight to lose. Not all of them got it, but a few did. Anyway, its a medication you cannot stop to take (to lose weight) because the tests show that you will regain all weight lost.
Best Startalk yet! I'd like to see more debate about causation and correlation. The most prominent AI algorithms ( neural networks, e.g.) are pure correlation where it is next to impossible to come up with a causal narrative to explain the correlation. If I were not on fixed income now, I would add to your Patreon right now. Excellent episode. Thank you.
I find it interesting that any of the lower carb diets have the same effect not only on type 2 diabetes, but also on the rates of Alzheimer's, the rates of PCOS, etc. 🤔
Similar here. Started at 243. Now 177 after 2 years. Rather elevated A1C, now very normal. I'm a 5'10" 46 yo male. I'm back to my college weight! Started with Saxenda for a year. Now on Mounjaro for the past year.
9:33 It's also that overweight people tend to be eating high carbohydrate diets which constantly spikes insulin which, over time, will lead to insulin resistance (type II diabetes)
@@kalijasin They are also more physically active so they are able to use the carbs they burn. It's likely also the case that they have higher muscle mass which pulls in glucose from the body for energy use in the muscles, so high carb diets are not as much of an issue for them.
Gyms used to not be so prominent in America before the 80s. Most people didn't exercise and were still in better health and far less obesity. Adopting a high carb diet(which all breaks down into sugar) has destroyed the mental and physical health of America. Carbohydrates are the only food macro that the body does not require have. Dig deeper ✌️
This was a great episode! I am now concerned of salty, high calorie dense foods and the comparison of them to semaglutide. Given all else remains constant, I wonder if the consumption of those foods over a period of time would have a greater negative effect (such as weight gained and higher cholesterol) than the consumption of semaglutide and similar drugs... This of course entails that you are not taking both simultaneously. Only time will tell the true effects.
Even if there is long term consequences of ozempic, it has to be considered that there are also long term consequences of obesity. So it’s either a miracle drug, if there are no long term consequences, or it’s a trade off, a trade off that is likely still worthwhile. I am on it now to help reduce my a1c and prevent diabetes. I also have severe sleep apnea from obesity which has caused me some medical problems in my life. Down 17 lbs already but need to lose 75 overall. Long way to go.
And I was wondering why I 'easily' quit smoking 2 years ago (after 3 failed attempts). I began Ozempic (for type2) the same week I started the nicotine patches and Champix!!!
Alzheimer's has been referred to as diabetes type III because of the correlation between the brain unregulated glycemic states. Off label usage is many times how therapies for other diseases are discovered. For instance Xeljanz; originally FDA approved for Rheumatoid Arthritis, was found to increase hair growth in patients who suffer from alopecia.
Off label prescription option is a real important mechanism for our ability to treat anything from headaches to multitude of conditions without we’d be significantly limited. It just requires physicians to have had experience with its usage and to foresee potential side effects.
I hope Star Talk and Dr. Nick Tiller see this, the lose of interest in food Dr. DeGrasse Tyson described sounds identical to the side effect I got from taking Concerta. Concerta for me wiped out my interest in food. The thought of eating food was sickening. When the med wore off in the evening, I would sometimes binge eat (sugary foods) what was in the kitchen but I also could not remember what healthy meals I enjoyed eating.
Question: In the wake of all of the Ozempic allegations and now-known side effects, I'm curious to know how they see the drug now? Does the doctor still hold the same opinion?
“You create your reality,” dear creator, you, so, you get whatever you concentrate upon as you hypnotize yourself with your personal prejudices. peace+&-. Thank you. 🎶💥🌸
I really envy those who don't seem to hold much body fat. It fits the modern lifestyle. The sad thing is that before humans began farming and settling, and access to food was more reliable, those who tend to hold onto body fat would have had a survival advantage. When you don't know when your next meal is coming, you want to hold onto those calories. In modern times, food access is no problem for many, so we really don't need to hold onto the calories as much.
ive been taking ozembic and its helped me lose weight and lower my a1c. But its been so damn hard literally impossible to find pharmacies that carry it anymore
Don't know what you've tried but the diabetic diet is the way to go if you want to loose weight. Just have to cut out sugars and processed food and, you never get hungry- a diabetic eats 3 meals a day and 2 snacks. How you give it a try and good luck! 💜
"People taking Ozempic tend to lose weight because they consume fewer calories, not because the drug itself magically burns fat" - Dr. Robert Gabbay, chief scientific and medical officer of the American Diabetes Association
I'm not big on quick fixes, especially when tied to behavioral issues such as eating or addictions. I have a sweet tooth and crave just about anything that is sweet. When I found out sugar was addictive, it explained why I had so many problems turning down sweets. To solve the problem, I began slowly cutting down my sugar intake. It has taken several years but I've now got it to a more manageable level without going through the deprivation process that causes relapses. I am doing the same thing with my favorite foods, that aren't very healthy, as I know it is easier to slide into diabetes as we get older and less active.
I started on Ozempic in February at a lower dose. My doctor upped the dose and the weight loss started. It lowered my A1C, and I lost approximately 25 pounds. I wasn’t as hungry but it also made me very nauseous. Who wants to eat when you feel like you are going to vomit? It also made me extremely constipated. When I went for a refill I was looking at an $800+ bill. Not sure if it was a 30 or 90 day supply. It didn’t matter because I am not going to spend that amount of money. Unfortunately, my appetite is coming back and I have gained 5 pounds. I need to suck it up and change my way of eating on my own. Hopefully my sugar levels stay in the normal range.
On your next doctor's visit, ask them for samples with the intention of stopping all together. Drug is super expensive and the nausea feeling for me was my body telling me we got this. No need to continue the drug therapy.
I’m a type two diabetic and I take zero diabetic medications. With the help of my doctor I went off of my meds by going on the ketogenic diet in 2019. Dropped weight and run on ketones for energy instead of glucose. My appetite control is a product of the ketogenic lifestyle. Not all type two diabetics need to live with medication(s). Make your choice.
I really wish they'd gone into some detail on how a drug like Wegovy could be used to treat ADHD. I really struggle to remember to take my meds and only having to take an injectable once a week would be amazing.
I have been on Ozempic for a few years and it is life saver for my type II and I hit a wall when I had to go without if for three weeks due to the shortage and saw my glucose levels get higher and my weight loss begin to reverse even with careful control of my meals. It was a rough three weeks and took a month go get back to where I was once I was back on the drug. The only thing I dislike (tongue firmly in cheek) is that I have to eat child portions of meals and it is a dice roll if I finish it.
I've used Monjaro (terzepatide), which usually goes unmentioned compared to Ozempic(semaglutide), for the past 8 months and have dropped over 80 lbs and kept it off. Terzepatide does the same as Semaglutide (GLP-1 agonist), plus it also mimics GIP (glucose-dependent insulinotropic polypeptide) hormone, which can also trigger insulin creation and sensation of fullness. Tirzepatide has yet to be FDA-approved for weight loss like Semaglutide has, so fewer people talk about it. Also, you have to pay out of pocket for it unless you have a diabetes diagnosis for now. I can afford it so I do and it's been a life changer for me. I come from a family of obese women from Mississippi, none of which life to very old ages so for me it's worth it to lead a healthier and hopefully longer life.
My wife is Type 2 diabetic, and until recently the only thing that was able to adequately control her blood sugar was Ozempic in addition to Glyclazide and a high dose (2000mg) of Metformin, so the sudden shortage of Ozempic had serious consequences and eventually as the shortage continued, she had to go onto insulin injections.. so its good to hear that the market will potentially be flooded soon with similar drugs.
I've been taking Phentermine for weight loss but I'm starting to build a tolerance to it because it's only 15 mg. I'd prefer to try Ozempic but I don't think I'd be able to get it.
Love the show. Anyone know if there has been a StarTalk about other health stuff like artificial sweeteners, alternative meats, etc? EDIT: I meant to say "alternative to meats" lol. I re-read it and said, yeah, I gotta fix that.
@noahway13 - yeah, I never understood why people do that. Don't write a new sentence explaining your edit. Just edit what needs to be fixed in the original post.
The problem with diets is that most people are liars. Not always deliberately, but their food/nutrition education is so bad and misinformed, that they have no idea what they're talking about or measuring. Even self declared "nutritionists." Every single episode of every single mass weight-loss show where a participant backslides, it's directly because they lie about what they are consuming. It doesn't matter how much "psychotherapy" and data you provide, their habits and behaviors around food have been nurtured literally since procreation. You can't babysit people 100% of the time to monitor this, so all of this "psychological" nonsense on food is moot. Be honest with yourself or you will fail. Sadly, for most people words are more important than actions, so they will always fail when action is required.
I have type 2 diabetes. 2 years before starting Ozempic I stopped drinking all soft drinks. Lost 50 pounds just doing that. Been using Ozempic for 8 months, lost another 25 pounds. Weird thing is now, I find eggs disgusting.
My mind jumped to the tick bites that sometimes change a person to become allergic to eating meat. It appears to be yet another inflammatory response. Might this be related to the workings that Ozempic uses to change cravings?
what is the similarity with ozempic and the ritalin related medicines. i know the base elements are also used for speed, and that is also a hunger blocker
19:27 if everyone in your life chose to do that, and you never saw others getting enjoyment then yes chuck, you are correct. We are social creatures…..
This was an awesome episode! I can't wait for Nick to be a guest on the show again. He had so much great information to share with us.❤
how anbout side effects? nausea etc?
Type 2 diabetic here... taking ozempic last 4 months lost 24 lbs and A1c went from 10.4 to 8.6 in 90 days... more to go, at least 20lbs to go also...besides the sometimes overwhelming nausea all's ok!
As a long term type 2 diabetic, Ozempic has been a miracle medication for me. For years I complained that I was always hungry and never felt full. I saw a therapist for years who specialized in over eating and diabetes. Guess what, did not help. Once I started ozempic, I now feel full, and I am not hungry all the time. There is also a genetic component to my diabetes. My grandmother from Finland had Type 2, all of her children developed it and so did her grandchildren. I resent the non diabetes who are using it to lose vanity weight. By the way, my last A1C was 5.7, in the normal range.
Totally agree: Ozempic is a game changer
You are doing great! However, 5.7 is actually at the bottom end of prediabetic. Excerpt from the CDC website: "A normal A1C level is below 5.7%, a level of 5.7% to 6.4% indicates prediabetes, and a level of 6.5% or more indicates diabetes. Within the 5.7% to 6.4% prediabetes range, the higher your A1C, the greater your risk is for developing type 2 diabetes."
I started on Saxenda, was on that for a year. I've been on Mounjaro now for a year. My A1C is now normal, and I'm down 66 pounds over the 2 years. I utterly love not ever feeling hungry since before, I always felt hungry even after eating a large plate of food. I've moved down to the 7.5 dose for maintenance purposes.
All the other drugs in the category are just the GLP-1. Mounjaro also has a GIP added to it which is a good addition. (Glucose-dependent indpsulintropic polypeptide) He talked about the half life. Mounjaro with the GIP increases the half life.
"People taking Ozempic tend to lose weight because they consume fewer calories, not because the drug itself magically burns fat" - Dr. Robert Gabbay, chief scientific and medical officer of the American Diabetes Association
Obesity is also a disease that leads to death. This is great to prevent everything that comes with obesity. One desease isn’t less deserving of a cure than another. Also obesity is the number one health problem in America
Thank you for having a thoughtful and fair minded skeptic on your show. It was so refreshing to have someone who was deeply educated in the topic talk knowledagbly about the issues in such a balanced manner. Too often skeptical perspectives can be so radical that they lose any appeal or crediblity with the audience, and any valuable insight they might have shared is lost because their positions feel too tainted. Dr. Nick Tiller set a new bar in my mind for what a respectable skeptic you can trust really looks like. Thank you for introducing him to us.
yeah right GPT
I started on Saxenda, was on that for a year. I've been on Mounjaro now for a year. My A1C is now normal, and I'm down 66 pounds over the 2 years. I utterly love not ever feeling hungry since before, I always felt hungry even after eating a large plate of food. I've moved down to the 7.5 dose for maintenance purposes.
All the other drugs in the category are just the GLP-1. Mounjaro also has a GIP added to it which is a good addition. (Glucose-dependent indpsulintropic polypeptide) He talked about the half life. Mounjaro with the GIP increases the half life.
Hello Jeff. Does your insurance cover the Mounjaro for continued maintenance purposes? I'm very interested in this as a sort of head start to help me get back into much better shape. But the cost seems prohibitive, if it cannot be prescribed "on label" for continued weight maintenance. I do in fact have very good insurance, but they have denied other "off label" prescriptions for members of my family.
@@scottyplug For the Saxenda, I think I had a discount card since my insurance wasn't covering it. At that time, it was Cigna. While on Mounjaro, I switched jobs and now have Aetna. They didn't cover it either. I used their discount card that made it $25 a month. After about 10 months, I exhausted the full coverage and it went up to just over $500. The next month after that one (last month), I paid $205. The pharmacy said my insurance covered it now as my doctor resubmitted paperwork and prior authorization to Aetna. I guess proof that I needed it and it was working? The one I just picked up was also ran through insurance, and I paid $25 again. If it stays that way, I'm golden!!
Please find a way to get Nick back on the show, even off-label!
It's a wow factor just how funny these guys can make any serious subject but I really appreciate how honest the good Dr. is in his willingness to say what we do not know.!
STAR ⭐️ TALK IS MY DRUG 😂
And proud of it! ;-P
Mines fentanyl...
And I’m addicted to lean 😂
And I’m addicted to lean 😂
And I’m addicted to lean 😂
Appreciating Chuck more and more.
I've lost 75 lbs with semaglutide. It really is amazing
Congrats! That's the one I use too and it's fantastic to eat so little and still feel full.
Any negative side effects from semaglutide?
Did your doctor prescribe it? I’m 300 lbs haven’t been diagnosed with diabetes.
@cozmo1266 I pay for it privately. I'm not sure it's fda approved for weightloss yet which is what insurance companies would probably want to see before being willing to pay for a prescription
Yes. More of Nick Tiller please.
Thanks y’all for taking about this. I take this medicine, at first I didn’t believe it would work. Since i was used to injecting myself twice daily. With Ozemptic I’ve been able to remove insulin all together. It’s really simplified my life.
yeah right GPT
yeah right GPT
Your camera looks better today, Dr. T!
Amazing guest and topic. Also, love when you guys cut out all of the break segues to make it more continuous and spare our precious time.
I’m a type two diabetic and I take zero diabetic medications now. With my doctor’s input I went on the ketogenic diet in 2019 and feel better than I have for years. You can run on ketones for energy instead of glucose. Dropped weight and my appetite control is a result of the ketogenic lifestyle. Make your choice. I did and will continue to do this lifestyle without meds.
Great episode of a great show. However, I was left a little muddy on what Nick is purportedly skeptical about. He said he was skeptical, and that he's a bit back and forth about whether to be skeptical or not. But then for the rest of the show everyone went on to emphasize how Ozempic and Wegovy are so effective. There was some mention of how it had better not have nasty side effects, with Phen Phen and FDA bureaucracy mentioned; and there was some commentary around the lack of availability for people who really need the drug due to celebrity promotion and off-label use. But I didn't hear any skepticism about the drug's efficacy or reasons why we otherwise shouldn't take it. Perhaps I missed that part?
They should have mentioned it but they didn't. Maybe I can save some people a trip to Dr. Google: "The most common Ozempic side effects are nausea, vomiting, diarrhea, abdominal pain and constipation. Serious Ozempic side effects include allergic reactions, changes in vision and pancreatitis
...
Ozempic has an FDA boxed warning for the risk of thyroid C-cell tumors 👀
...
In animal studies, Ozempic caused abnormalities in fetuses. 👀
...
Acute gallbladder disease, Acute kidney injury, Allergic reactions, Diabetic retinopathy, Hypoglycemia (when used with insulin or sulfonylurea)... 👀
I used Saxenda for two months but didn’t inject every day. I only injected every 3rd day and that worked for me. I lost 15% of my body weight. During the time I was on it, I chose to adopt healthy eating habits and portion control. One year on and my weight is the same. You do not need to stay on this for the rest of your life unless you chose to go back to the eating habits that made you overweight to start with.
Yeah, there truly isn't a miracle drug yet. It still comes down to changing to a healthy lifestyle.
A doctor once told me that losing weight reduces the size of fat cells, but doesn't remove them and that it takes 3+ years for the starved fat cells to start dying and being removed from the body, so to make losing weight last one needs to maintain the low weight for at least 3-4 years after reaching it. If that is the case with fat cells, a weight loss therapy should require both reaching the desired weight and then keeping it for 3-4 years after reaching it. This could be setting a time table for weight loss usage of medicines.
They mentioned covering the side effects but never got to it. I think that’s important to understand.
This was easily one of the better semaglutide related podcasts
Guys I love you, get some images about the things you teach us please 😢 like the Lizard venom. I would’ve love to see the lizard.
This episode should be called “Inner Space”. Enjoyed it immensely!
This is good. As a type 2 diabetic, my doctor recently prescribed Ozempic and mentioned the weight-loss aspect as well - but I didn't know how it worked. Considering I'm rather overweight/obese (30+ lbs), this seems like a good solution in addition to the other things I should be doing. Especially as a diabetic, I'm constantly fighting the desire to eat and drink. I think the main kicker is that it might not be covered by my insurance. Also, if Ozempic isn't available, that could be a problem for me. Since I wear a continuous glucose monitor, which does help with knowing what's going on with food and medications.
yeah right bot
@@jennjennjenn61992 Whatever troll. Get bent.
I am a type II diabetic, since i got pregnant in 2000 and after using 3 different medication and still was not totally controlled. 2 years ago, my endocrinologist and I decided to try Ozempic. It has been a miracle for my diabetes control. Yes, I have lost a lot of weight, around 30 pounds on it, but the way I got there was not fun at all. The side effects were very strong, but because of its amazing effect on my diabetes, I stuck with it. Now though, I'm having to pay through the roof because the pen with the larger dosage is back ordered and have to pay the smaller dosage pen twice a month. I really wish doctors would be more sensitive to those who NEED it before just prescribe it to people that don't need it, but only want to lose some weight. Its always about the money at the end.
I don't have diabetes, but am overweight, and I get liraglutide, which is mostly the same. Luckily doctors here do not give it out that easily, you have to fit certain requirements to be able to start with it. People just can't get it to quickly lose some weight so they can have that slim beach body or fit in their old dress for a wedding in a few weeks. It's only for people who really struggle with their weight.
You are in my definition of "needing" it! I know quite a few persons that asked for it with minimal weight to lose. Not all of them got it, but a few did. Anyway, its a medication you cannot stop to take (to lose weight) because the tests show that you will regain all weight lost.
I have 2 pens i can pass for cheaper than official price if anyone interested...
I have 2 pens i can pass cheaper than official price, if anyone interested...
cool story GPT
His interviews may be all over the place but I'd love to hear a conversation between you guys and Peter Attia
They actually did an interview with him before. I think they should have touched on nutrition more though.
ua-cam.com/video/xa41LPpap6k/v-deo.html
he was on a few months ago!
@@aboynts456I've seen it! Thanks so much!
Love Nick’s reading selection.
It works and is amazing. I'm down 40lbs so far, in 6 weeks. I hope they make it cheaper and increase supplies.
In the EU 1 shot containing 4x 1000 mg doses costs $130.
Exact same thing in the US is $800.
Seems like alot...
Best Startalk yet! I'd like to see more debate about causation and correlation. The most prominent AI algorithms ( neural networks, e.g.) are pure correlation where it is next to impossible to come up with a causal narrative to explain the correlation. If I were not on fixed income now, I would add to your Patreon right now. Excellent episode. Thank you.
I find it interesting that any of the lower carb diets have the same effect not only on type 2 diabetes, but also on the rates of Alzheimer's, the rates of PCOS, etc. 🤔
As someone who used to work in pharma, this was a well-managed discussion on pharmaceutical issues.
Phenomenal episode! Really enjoyed it.
Really whish you could do a show concerning the supplement NAC and it's effects on a drug use disorders, please.!
Dr. TYSON, please I beg. Come do a talk in Las Vegas.
I've been on OZEMPIC for about 1 year. The only side effect is that I've lost about 20 lbs 😅 Now I feel thin.
Gary - “and then 420”!!! 😂 I love the Mary Jane reference at 1:36
Thank you!
I started at 212 lbs. and am now 170 . 42 ibs. lost - life changing !!!
Similar here. Started at 243. Now 177 after 2 years. Rather elevated A1C, now very normal. I'm a 5'10" 46 yo male. I'm back to my college weight! Started with Saxenda for a year. Now on Mounjaro for the past year.
I thought Nick was a well put together robot. His filter is amazing 😊
9:33 It's also that overweight people tend to be eating high carbohydrate diets which constantly spikes insulin which, over time, will lead to insulin resistance (type II diabetes)
Pro Cyclists are some of the skinniest people in the world and Pro Cyclists tend to consume looots of carbs.
@@kalijasin They are also more physically active so they are able to use the carbs they burn. It's likely also the case that they have higher muscle mass which pulls in glucose from the body for energy use in the muscles, so high carb diets are not as much of an issue for them.
@@jonathanmoody8757 Exactly. Its not carbs but rather a lack of exercise.
Gyms used to not be so prominent in America before the 80s. Most people didn't exercise and were still in better health and far less obesity. Adopting a high carb diet(which all breaks down into sugar) has destroyed the mental and physical health of America. Carbohydrates are the only food macro that the body does not require have. Dig deeper ✌️
alcohol and hard drug addiction seems a lot worse than taking this drug. There has to be a way to speed up that process
Fantastic episode. Thank you!!!
This was a great episode! I am now concerned of salty, high calorie dense foods and the comparison of them to semaglutide. Given all else remains constant, I wonder if the consumption of those foods over a period of time would have a greater negative effect (such as weight gained and higher cholesterol) than the consumption of semaglutide and similar drugs... This of course entails that you are not taking both simultaneously. Only time will tell the true effects.
High carb diets cause obesity. Why you ask. Because it will cause never ending hunger.
I am interested to understand if (modified) fasting really does decrease inflammation. Would love an episode on that.
Even if there is long term consequences of ozempic, it has to be considered that there are also long term consequences of obesity. So it’s either a miracle drug, if there are no long term consequences, or it’s a trade off, a trade off that is likely still worthwhile.
I am on it now to help reduce my a1c and prevent diabetes. I also have severe sleep apnea from obesity which has caused me some medical problems in my life. Down 17 lbs already but need to lose 75 overall. Long way to go.
Life is pain, anyone telling you different is trying to sell you something.
As a diabetic sufferer and ozempic supply problems is very problematic for me
And I was wondering why I 'easily' quit smoking 2 years ago (after 3 failed attempts). I began Ozempic (for type2) the same week I started the nicotine patches and Champix!!!
love your channel ! thank you !!
Alzheimer's has been referred to as diabetes type III because of the correlation between the brain unregulated glycemic states.
Off label usage is many times how therapies for other diseases are discovered. For instance Xeljanz; originally FDA approved for Rheumatoid Arthritis, was found to increase hair growth in patients who suffer from alopecia.
Really enjoyed this conversation - Dr Tiller is an excellent guest 👌🏽
Off label prescription option is a real important mechanism for our ability to treat anything from headaches to multitude of conditions without we’d be significantly limited. It just requires physicians to have had experience with its usage and to foresee potential side effects.
Does ozempic also control the urge to look at your phone? 😂
I've lost around 160 pounds 380-220. The discouraging part is according to the BMI calculator, I'm still considered obese.
Thank you for this!
loved seeing Dr. Tyson on sam and jim. schooled the mouth breathers.
Great episode. No stars ⭐️ but still full of info.
I hope Star Talk and Dr. Nick Tiller see this, the lose of interest in food Dr. DeGrasse Tyson described sounds identical to the side effect I got from taking Concerta. Concerta for me wiped out my interest in food. The thought of eating food was sickening. When the med wore off in the evening, I would sometimes binge eat (sugary foods) what was in the kitchen but I also could not remember what healthy meals I enjoyed eating.
Question: In the wake of all of the Ozempic allegations and now-known side effects, I'm curious to know how they see the drug now? Does the doctor still hold the same opinion?
Unfortunately, Type II diabetics can't get the Continuous Glucose Monitors(CGM). Insurance companies won't pay for them unless you are a Type I.
Nick just has so much knowledge. This was a great ep.
Awakening is the antidote for addiction and being a miserable human. Cannabis is wonderful plant medicine. 🥰✌️
Great episode!🎉
“You create your reality,” dear creator, you, so, you get whatever you concentrate upon as you hypnotize yourself with your personal prejudices. peace+&-. Thank you. 🎶💥🌸
This was so educational, thank you 😊
I want to know what Dr. Tiller, and Gary have on their bookshelves. I recognized a few labels
I really envy those who don't seem to hold much body fat. It fits the modern lifestyle.
The sad thing is that before humans began farming and settling, and access to food was more reliable, those who tend to hold onto body fat would have had a survival advantage.
When you don't know when your next meal is coming, you want to hold onto those calories.
In modern times, food access is no problem for many, so we really don't need to hold onto the calories as much.
You alone, decide what, how often and how much to eat..
ive been taking ozembic and its helped me lose weight and lower my a1c. But its been so damn hard literally impossible to find pharmacies that carry it anymore
Don't know what you've tried but the diabetic diet is the way to go if you want to loose weight. Just have to cut out sugars and processed food and, you never get hungry- a diabetic eats 3 meals a day and 2 snacks.
How you give it a try and good luck! 💜
"People taking Ozempic tend to lose weight because they consume fewer calories, not because the drug itself magically burns fat" - Dr. Robert Gabbay, chief scientific and medical officer of the American Diabetes Association
@@barbaraellmore9474 get lost, adults talking here
Chuck has really grown! Asking deep questions. Go ahead Mr Nice! Go put some initials after your name
I'm not big on quick fixes, especially when tied to behavioral issues such as eating or addictions. I have a sweet tooth and crave just about anything that is sweet. When I found out sugar was addictive, it explained why I had so many problems turning down sweets. To solve the problem, I began slowly cutting down my sugar intake. It has taken several years but I've now got it to a more manageable level without going through the deprivation process that causes relapses. I am doing the same thing with my favorite foods, that aren't very healthy, as I know it is easier to slide into diabetes as we get older and less active.
Remember as the song goes; "In heaven there is no beer. That's why we have to drink while we're here".
I started on Ozempic in February at a lower dose. My doctor upped the dose and the weight loss started. It lowered my A1C, and I lost approximately 25 pounds. I wasn’t as hungry but it also made me very nauseous. Who wants to eat when you feel like you are going to vomit? It also made me extremely constipated. When I went for a refill I was looking at an $800+ bill. Not sure if it was a 30 or 90 day supply. It didn’t matter because I am not going to spend that amount of money. Unfortunately, my appetite is coming back and I have gained 5 pounds. I need to suck it up and change my way of eating on my own. Hopefully my sugar levels stay in the normal range.
On your next doctor's visit, ask them for samples with the intention of stopping all together.
Drug is super expensive and the nausea feeling for me was my body telling me we got this. No need to continue the drug therapy.
I’m a type two diabetic and I take zero diabetic medications. With the help of my doctor I went off of my meds by going on the ketogenic diet in 2019. Dropped weight and run on ketones for energy instead of glucose. My appetite control is a product of the ketogenic lifestyle. Not all type two diabetics need to live with medication(s). Make your choice.
I really wish they'd gone into some detail on how a drug like Wegovy could be used to treat ADHD. I really struggle to remember to take my meds and only having to take an injectable once a week would be amazing.
I have been on Ozempic for a few years and it is life saver for my type II and I hit a wall when I had to go without if for three weeks due to the shortage and saw my glucose levels get higher and my weight loss begin to reverse even with careful control of my meals. It was a rough three weeks and took a month go get back to where I was once I was back on the drug.
The only thing I dislike (tongue firmly in cheek) is that I have to eat child portions of meals and it is a dice roll if I finish it.
Skeptics unite!!!
We need to fix and regulate the food system like tobacco.
How might this medication affect someone overweight but who also frequently does not have an appetite and/or derive enjoyment from eating any foods?
Excellent!
I've used Monjaro (terzepatide), which usually goes unmentioned compared to Ozempic(semaglutide), for the past 8 months and have dropped over 80 lbs and kept it off. Terzepatide does the same as Semaglutide (GLP-1 agonist), plus it also mimics GIP (glucose-dependent insulinotropic polypeptide) hormone, which can also trigger insulin creation and sensation of fullness. Tirzepatide has yet to be FDA-approved for weight loss like Semaglutide has, so fewer people talk about it. Also, you have to pay out of pocket for it unless you have a diabetes diagnosis for now. I can afford it so I do and it's been a life changer for me. I come from a family of obese women from Mississippi, none of which life to very old ages so for me it's worth it to lead a healthier and hopefully longer life.
Thanks!
Amazing content/video, thank you all again!
Great information
My wife is Type 2 diabetic, and until recently the only thing that was able to adequately control her blood sugar was Ozempic in addition to Glyclazide and a high dose (2000mg) of Metformin, so the sudden shortage of Ozempic had serious consequences and eventually as the shortage continued, she had to go onto insulin injections.. so its good to hear that the market will potentially be flooded soon with similar drugs.
Great guest
I've been taking Phentermine for weight loss but I'm starting to build a tolerance to it because it's only 15 mg. I'd prefer to try Ozempic but I don't think I'd be able to get it.
How would this drug effect an individual with ADHD or similar conditions that already have low dopamine levels?
Love the show. Anyone know if there has been a StarTalk about other health stuff like artificial sweeteners, alternative meats, etc?
EDIT: I meant to say "alternative to meats" lol. I re-read it and said, yeah, I gotta fix that.
Why not just fix it instead of writing a whole new sentence?
@noahway13 - yeah, I never understood why people do that. Don't write a new sentence explaining your edit. Just edit what needs to be fixed in the original post.
I like alternative meats... pangolin, bats, krab, that sort of thing.
OMG I have managed to sit on the toilet for this whole episode...I can't feel my legs.
iv found that these seem to be helping with some of the effect of ms, so i hope i can keep being able to find it
The problem with diets is that most people are liars. Not always deliberately, but their food/nutrition education is so bad and misinformed, that they have no idea what they're talking about or measuring. Even self declared "nutritionists." Every single episode of every single mass weight-loss show where a participant backslides, it's directly because they lie about what they are consuming. It doesn't matter how much "psychotherapy" and data you provide, their habits and behaviors around food have been nurtured literally since procreation. You can't babysit people 100% of the time to monitor this, so all of this "psychological" nonsense on food is moot. Be honest with yourself or you will fail. Sadly, for most people words are more important than actions, so they will always fail when action is required.
Like people who think drinking tons of fruit juice is good for losing weight
I have type 2 diabetes. 2 years before starting Ozempic I stopped drinking all soft drinks. Lost 50 pounds just doing that. Been using Ozempic for 8 months, lost another 25 pounds. Weird thing is now, I find eggs disgusting.
My mind jumped to the tick bites that sometimes change a person to become allergic to eating meat. It appears to be yet another inflammatory response. Might this be related to the workings that Ozempic uses to change cravings?
Remember - insurance does not cover meds prescribed for off-label use.
what is the similarity with ozempic and the ritalin related medicines. i know the base elements are also used for speed, and that is also a hunger blocker
Is there a generic brand non prescription that is similar
Not yet
19:27 if everyone in your life chose to do that, and you never saw others getting enjoyment then yes chuck, you are correct. We are social creatures…..
Ahhh, gettin' my fix of StarTalk. GREAT stuff, AWESOME head-change, PERFECT as always. ;-P
Suggestion: Dr. Anna Lembke and Dr. Nick Tiller in one special episode.
I hope you will invite Dr. Robert Lustig too some day.
10:56 😂"Alright" trying, like a teacher, to reign in the conversation from Sir-Mix-A-Lot.
I love this doc. Mr. Tiller had me at Neil Gaiman already 😀