@@DavidThackerMusic same here with a BS in physics. I'm no expert in chemistry but I'm an engineer and I grow specialty mushrooms. I wonder if there's some interesting experiment I could perform on my fungus.
Seems more like multiple noble prices: cracking the bioelectric Code. Potential curative treatments for birth defects and cancer. A revolutionary Paradigm shift in how anatomy is organizrd. A completely non random understanding of evolution.
This video is so underrated. Beautiful discoveries. We need to create a huge dataset of electrical signal patterns morphology tuples and train some generative ML models on it. Imagine specifying a morphology and the model spits out the necessary electrical pattern which you could then apply to build a limb, etc. I'm obviously simplifying but that's roughly the idea.
Awesome to see you here too, I'm currently in college and really appreciate your channel! I also get the sense that there is an insane amount of overlap between machine learning and biochemistry, and I suspect that isolating biological subroutines (especially involving growth and regeneration) is going to be a game changer! ✌
This is one of many young great minds of our time. I would like to know if Dr. Michael's works are included in medicine soon, and to cure some diseases we don't have a cure for?
Michael, very solid work. You took Driesch to a whole new level! Would you agree that what you call “modular” can be viewed as some form of biological quantization? Thank you
They don’t, and Levin doesn’t link bioelectricity with sheldrake’s morphic fields. Levin calls morphogenesis completely physical. But to sheldrakes credit- where does a bio electrical algorithm exist? It’s a good question.
@@LS-qu7yc I've been curious about the same thing. If there is electricity there has to be an electrical field that is atleast in some part reaching beyond its physical constituents. What all could it be interacting with? Moreover, how do the components (protein channels) to create the electric field get there in the first place? If DNA does not determine anatomy, then how do the proteins that make up the ion channels get in the right place to begin with?
Hello and thanks for the brilliant talk! Besides birth defects and the others applications mentioned here, I can already envision how this capability could be useful for burn victims or acid burn victims and so on, as well as outright recreational "plastic surgeries" or the like. Such interesting stuff!
Later… his work opens up what seems metaphysical to main stream science. They don’t want his work to be true. It will require many independent replications over a decade. Yet if he produces something that will be worth billions or trillions in regenerative medicine, then he will be put on a pedestal
Absolutely beautiful description of the path from parisitosis to symbiosis obtaining homeostasis! The Collective Consciousness coupled to the Universal Consciousness from the seat of the Human Holographic Mind’s Eye! Shine Bright! Frequencies is the system of our symphony!
What determines the initial placement of the ion channels if DNA does not determine anatomy? Also, what determines that the correct ion channels get expressed? If bioelectric potential, the software, comes first in determining which hardware gets expressed, what is determining bioelectric codes for each cell?
Hi, I have Multiple Sclerosis. So obviously I feel like you should look into this disease. My thought is this; In @Lex Friedman Podcast you mentioned immune therapy vs. other cancer therapy radiation. AND you mention electrical communication between cells. Multiple sclerosis is thought to be an Immuno-neurological disease, so I thought, maybe you want to talk more about a connection there. Reguardless, thanks. Thank you. I literally want to live again because there may be a chance you be like that guy who cured polio ( sort of ;/)
Hello, I wanted to say that I really relate to this comment. My mom has advanced primary progressive MS and I’ve spent a lot of time listening to talks and lectures of highly educated people like Michael Levin trying to find a common thread. I’m fascinated by the point you’ve brought up and I would love for him to touch on that. Have you heard of Dr. Terry Wahls? She’s a neurologist that reversed her own progression of MS. It’s amazing. She believe autoimmune diseases are a dysfunction of the mitochondria not being able to correctly metabolize and communicate to the cells. She uses diet and supplementation to support the mitochondria. My mom is 62 (which is a miracle), and I believe that following this protocol has prolonged and slowed to progression to a certain degree. I just wanted to share her experience and see if maybe it’ll make a difference for you. I wish you the best on your life journey ❤ Hope you find this helpful
The short is is yes. Yes I have heard of The Terry whals protocol. More importantly, your comment is caring, and I cannot describe how much it means to me. My life is foreign to me. I want you to know, a PERFECT addition to the T.W.P. Is exercise. This includes bed exercise, elastic band exercise, chair yoga, etc. The results are undeniable. I have found no one with MS, that does not see its benefit. I sincerely hope you and your mom to understand you got a fan a me.🥰🙂 Thank you for showing your care!!!!!
@@izitmepattavina8651 exercise should be mandatory of every person regardless of condition. I have adhd and I like to think it helps but in reaility its just good to work out
This science deserves a Nobel prize soon. Also his discoveries are definitely at the level of Nobel discoveries such as the photoelectric effect, quantum mechanics, quarks, etc...
Searching for Michael’s work after the Lex interview. On xenobots, I don’t think you can say evolution never experienced this state before. Surely way back in time there was a primitive tiny organism with did use cilia to move. The cilia later got repurposed to move mucus. Isn’t it likely the skin cell reverted to an earlier evolutionary state without the high level control of the larger organism?
Plasticity without genetic change, as seen in bioelectric embryos and synthetic proto-organisms, reveals a fascinating layer of biological adaptability that goes beyond our traditional understanding of genetics. Bioelectricity, the natural electrical patterns generated by cells plays a crucial role in shaping an organism’s development, guiding cells on when and where to grow, differentiate, or even repair themselves. This form of control suggests that biological forms can be sculpted and restructured by manipulating electrical signals, without altering the underlying DNA. In bioelectric embryos, researchers have demonstrated that tweaking electrical gradients can induce cells to form new structures or repair damaged tissues, essentially allowing the organism to ‘rewrite’ its blueprint on the fly. Synthetic proto-organisms, meanwhile, harness this same bioelectric potential, allowing scientists to create life-like behaviors in non-genetic systems. These proto-organisms exhibit forms of movement, self-organization, and responsiveness typically attributed to living beings, all orchestrated through electrical cues rather than genetic instructions. This plasticity challenges the gene-centric view of biology, suggesting that life is not solely governed by DNA but is instead a dynamic interplay of genetic, biochemical, and bioelectric signals. It opens up a new frontier in understanding how life can be engineered, manipulated, and potentially created from scratch, where the blueprint is not just written in the language of genes but in the electric whispers that flow through cells.
I would be interested to know whether cell differentiation into various tissues can be controlled through gene expression, via changes in vitamin D3 dosage or production. We know mutations offer variation in conferred attributes whether useful or dangerous, so it would be interesting to know how, for example, lighter skin colour with less pigmentation evolved through that mechanism as it relates to D3 dosage. Using the skin pigmentation mutation response, to lowered light conditions, as a guide to likely gene expression per se, if DNA and genes in particular as stated at 5:09 do not confer cell differentiation, and therefore variation in physical characteristics, what is the mechanism?
Amazing! I love hearing any updates from Dr. Levin’s research work. Each time it’s mind bendingly fascinating and so cutting edge compared to anything else out there it makes me think and hope for cures being developed for terrible diseases that will make them a mere past relic like small pox or polio for the most part. I’m sure some biohackers will take certain aspects farther once it becomes more widely understood and create strange human mods for unforeseen purposes made possible only through this type of fascinating advances in biological knowledge. Ethics aside of course, since what the mainstream deems unethical only drives such fringe practices underground.
Is there a hierarchy of priority for each cell type? In the example of producing an eye in the tail of the tadpole, what kept the skin cells from reverse recruiting the induced eye cells to work together to go back to make skin?
Amazing projection of anthropomorphism revealed in the phrase 'evolution discovered'. Charge separations and discharge paths self organise to 'cells' or boundary conditions within filamentary 'structures' at all scales, but expressing according to terrain which is of course part of as well as party to such expressions. Infinity is neither big or small but is Totality or Whole. In an object model, we discard Infinity with such ideas as 'space' which is 'full' in terms of 'fields' regardless the interactions that we call matter and associate with thermodynamics. The initial discovery of bio-fields is to the ego of a mindset of predictive control - which is alien to life - or I might say the result of an alienation from our original nature or identity at rest (field-guided) as distinct from isolated central 'control' based on conditioning or acquired experience along the lines of its 'survival' as a self-referencing thought system or focus for creating experience. That there is a reintegrative field awareness for conflicts, fragmentation and dysfunction is effectively blocked by the persistence of a control directive rising from separation trauma - loss of field (felt) awareness of Infinity as our own resonant signature vibration. yet even such limitation and dysfunction is information serving a greater 'self-organising' or creative expression of life as embodied awareness of existence - ( as distinct from self-conscious reflective thinking), Existence cannot be truly outside a field that we can access as awareness THAT we are (without qualification). Somewhere in attempts to DO life, we may discover an always already 'intelligence' of integrality which realigns or restores unified purpose to fragmented or split and chaotic disorder. The discovery of what we are from new perspectives is the essence of living thought that goes forth to multiply. The idea of hacking the code is the idea of private creation, within a Field that is within all that is as a river is within its eddies - that none the less embody characteristics of a persistent boundary event around an inertial fulcrum. Ideas here are sketching, to prompt, invite, but not 'tell'.
This is like a thousand years ahead of its time. Move over Dr. Frankenstein, there's a new Doc in town !Now that I think of it Dr. Frankenstein used electricity to bring his monster to life ! But like wow. This is truly amazing.
So - instead of transmitting information between cells via cell surface-bound molecules, the membrane potential is used. This quite an insight and a revolutionary one, too. Since there is only one type of electricity, similar voltage patterns must be used for different differentiation patterns, right? How far does this go? Is there a level in cell differentiation at which a switch from membrane potential patterns to other mechanisms is made? Or do cells run through a repeating process during each step of their differentiation (I'm part of leg/foot/toe/nail)? Can you de-differentiate cells just by altering their membrane potentials or is it only the (largely undifferentiated) stem cells which are susceptible to changes in the bioelectric environment? How does DNA methylation fit into this? Could DNA demethylation be used to start a regenerative bioelectrically controlled process? So many questions...
Michael, At 28:53, you discussed placing animals into completely new environments, resulting in the organism's changing its expression in channels (ie, the morphogenetic fields). Then you expressed that this could result in development of an entirely different creature. I study evolutionary biology as a layman (science major), and this would be a mechanism of very rapid evolution, say at a time of going from a long Snowball Earth 670 MYA and into the warm Ediacaran Period when quite a few new body patterns started to emerge (the Avalon Explosion). Then from 542 MYA, the Cambrian Explosion took place (creation of 7 new phyla in less than 50 MY. This second explosion might have been driven by the completely new environment of more available oxygen in the ocean (from a huge increase of algae in the ocean). This also could be seen as changing expression in channels to produce very different creatures? Perhaps you can give me feedback on this simplistic way of looking at it!
"Placing animals into completely new environments". Virtual reality tools/environments might be a evolutionary change for humans. Experiencing adventures, risks and encounters, which humans would not otherwise be challenged within their safe environment.
I'm starting to imagine oceans being this ginormous volume filled with trillions of molecular level electrical potentials due to the various salts ions. What if life is the electrical evolution of this electric field's "soup" through chemical means and structures? Regardless of the explanation, I do still stand with the idea that the world being a pre-made platform with the design intention to sprung life, which I find incredibly fascinating tbh
@@alihyari7358 I would suggest creating Life is more complex, than the "electrical field soup with chemical" interaction. Otherwise modern scientists would be creating living organisms from the mere combination of electrical soup and chemicals. Having said that, materialistic scientists will find that they cannot create Life (living organisms) using just lifeless molecules. ⚛️ Atoms are Not the source of LIFE.
Like all great science this creates more questions than answers. It opens up new regions for exploration. "When you have eliminated the impossible, whatever remains, however improbable, must be the truth." S Holmes. 'Whatever remains' in this case is a whole can of worms.
Wow this some scary amazing shiz bro. Thinking someday we could make a treatment for dismemberment or metastatic cancer for people! What a wonderful world we live in!
I wouldn't say that. Knowledge gained form advancements of these fields may also be of great use to us. We do gain technological advancements from a lot of knowledge generated there. Besides, unraveling the mysteries of the universe to get answers to fundamental human questions (Where do we come from, how was the universe created, what is life/consciousness, etc. etc.) is what drives our species since ancient times. Its why so many different religions and stuff was invented, because without answers these questions keep people awake at night. Not to forget that IF Penrose & Hameroff are actually right in with their presumptions in the Orch OR model, research in these fields could also immensly contribute to our understanding of consciousness.
Bravissimo...deep intriguing need to watch over & over...so much to absorb...hope me pea brain can handle info load...maybe I should grow a 2nd head...
This research breaks down the "I" to a cellular level. Still, every "I" is subject to a blueprint existing in the bioelectric structure. Those blueprints, in more complex organisms, exist in a hierarchy of blueprint networks, almost like LANs in a hierarchical WAN, where the topological structure of the entire network is propagated down into the lowest entity that can hold the information. Which in simple organisms means the individual cells, but in higher organisms like frogs perhaps means one or two orders up in the network hierarchy. Perhaps this is why the xenobots will not try to recreate a frog while the flatworm will regenerate entirely from every subdivided part? Anyhow - amazing science, love it!
❤❤Fantastic science. Uncovering revolutionary causes in embryology, combining broad techniques-an easy Nobel prize decades ago. Science is accelerating. You just have to be ignorant of contemporary science to believe otherwise.
I don't understand : if the bioelectrical pattern is not coded in the DNA, where does it came from ??? the first cell must have it encoded somewhere, right ? where the anatomical blueprint came from ???
4:30 Is It Possible That Some Of The Cellular Structures Do Receive, Percieve, Or Transmit Forms Of Intrinsic External Information And Logical Instructions From Universal Pattern, As In Addition To The Technologies Inherent With Genetic Sequencing And Material Mechanisms?
'On Intelligent Systems' (July 30th, 2022) 'I Am Unsure Of Whether Or Not This Explaination Will Translate Appropriately To Someone Who Is Well Versed In The Terminologies Of Digital Semiotics; Reguardless, In Significant Brevity, One Of My Insights, As For A Somewhat Self-Governing And Self-Correcting System, Was To Functionally And Dynamically Layer The Logical Algorithms And Encrypt The Genetic Code To Specifically Keyed And Rooted Developmental Progressions, Exampled Such As With Stable Definitional Virtues Integrated Directly Into The Circuitry And Kernel And Operational Functionality, Intended To Be Discovered, Unlocked, Unfold, And Then Potentiate Along Correspondingly Contingent Developmental Boundaries, Dynamically Expanding Or Contracting In Capability And Functionality, Accordingly And Harmonically Relative To Accurately Delineated Conceptual Attributes, Multifacited MetaPhysical State Parameters, And Independently Appropriated Individualizing Context.' (Verify Truth)
How much memory is required to run a universe? Quadrillion billion gigabytes? If this was all a simulation.... i mean the level of complexity here is just absolutely mind blowing and the innate intelligence that appears to be built into every cell through the alternating pairs of sequences known as ACGT just blows my mind. This talk was fascinating.
@@Z3ROWOLFHD I also doubt that our universe is being simulated physically somewhere else. But just because we are not a simulation doesn't mean we can't share fundamental conceptual properties with our idea of simulation, there may even be a non local component (which is complicated for linear beings like us). If intelligence is the same end by different means, and our our objective reality is the "end", then how many different means could probabilistically lead here? Is our own Intelligent perception of the "now" a sort of simulation based on the type of information our brains can process? I know you said putting aside higher dimensions for a second, but I guess that's where I'm going with this. It's mind bending to think that complex cellular structure could be encoded in the bio-electric field of a single cell. I wonder what other kinds of structural information is embedded in the fields that permeate our universe, binding matter and shaping spacetime through their physical interactions.
Actually like our modern simulations, the only data that is necessary is the data needed to occupy your consciousness, therefore the amount of data is exponentially decreased
Adaptive morphology is something people totally forget about as well. Our genetics gives the essentials but environment can modify morphology dramatically. Especially in plants.
This isn't my field so this is going to sound stupid, but after Michael mentioned that the organism can reach the desired morphology from a variety of initial states and through a variety of paths, it sounds like it the assembly isn't really what's controlled but the final state. I imagine that things are going around randomly until they stumble upon and snaps into the stable position. However this model seems to be in contradiction with the relatively repeatable stages of development.
I would say two things: 1) This knowledge is more dangerous than that of nuclear bombs, and should be treated with extreme caution. Our species has repeatedly shown it is incapable or unwilling of having such caution. 2) What you would need to know to truly understand all this is many many many orders of magnitude beyond what any human has ever understood. People routinely underestimate the knowledge they would need, and act on the presumption that the tiny amount of knowledge they have is enough to make an intervention or create a product. I'll leave it to you to figure out what I think of the outcomes of such decisions.
Is the bioelectricity inherited from the parent/parents.... Highly likely. Can the bioelectricity/bioelectric field persistent if the physical animal dies? Maybe? 8 megahertz is the brains frequency.
Not sure why UA-cam recommended this video to me, but dang the algorithm got that recommendation right. Very cool video. Kinda weird and freaky but very cool.
"Kinda weird and freaky". Yeah. But totally in line with the politics of transhumanism as pushed by Klaus Schwab and his buddy Yuval Noah Harrari. Zis stuff doesn't happen aczidenzally. Ze AI algorithm iz already directing us into the diztopia zat is being pushed by ze United Nazions zustainable zevelopment goalz. You will own nothing, have no privazy, no memory and no identity and you will be happy.
When I come to think of it a little more, it already happened. Look at what's going on with their new mRNA techniques. Despite hardly being tested and with dangerous and deadly outcomes already manifesting, the US CDC is already on it's way to make them obligatory parts of the vaccination package for six month old infants.
"We are very far away from this." I'm optimistic about ML's work. When I hear these types of statements about the progress of state of the art tech, I wonder, "far away," in what relative time frame? A personal lifetime, the lifetime of a society, the lifetime of industry?
He has a lot of entrenched thinking to rewire. His work might explain miraculous healings. Need the correct morphogenetic field to push our organic goo into doing want we want
Levin, is a very bright, articulate guy, at the cutting edge of bio-physics, bio-electric research and applications. BUT, he immediately exposes the prevailing incomplete understanding and confusion Re: living vs non living, and commits the tautological blunder of assuming that the process of evolution exhibits intention, and bestows it with engineering capability and design. Evolution is a blind, dumb process of spontaneous mutation and natural selection, and most certainly is not responsible for bio molecular complexity of living things at various levels from cells to Levin-like humans. The origin of life is still very much a mystery. We have copied nature, and mastered CRISPR-Cas, for example, but how did bacteria develop it before us? In the cytoplasm of a single cell there is much going on without human direction or meddling. How does this happen? Why? Reducing all complexity down to a few basic physical forces seems naive, as well.
@@quantumdothunter Richard Dawkins can easily be bribed by offering him some good intentions and SJW anti racist values. In return he will water down his theory as much as needed for atheists to go to heaven and enjoy eternal equality.
I always hear so much that comes from idealism philosophical /theoretical lines of thought .really contradictory to past materialist belief systems. Regeneration , machines,programmed information in the same sentences with advancing changing evolution inserted words. manipulated etymology
He won’t like it but his work lends credence to consciousness is the master. Some causal astral field designing humans? Does the field stay “conscious” when cells die?
Not to diverge on too great a tangent, but I wonder if this bioelectrically-coded pattern memory is what some "spirit photographers" actually capture when they take pictures of, say, a ripped leaf, where the part that was ripped off's "aura" was still visible?
this guy isn't ''walking on earth'' either , might as well be a religious person with his head in the clouds , people just don't see what this person is telling them , that things have a ''choice'' in the matter ... nothing has a choice , it's all determined ... even the mold he tested that grows towards the most mass , the mold doesn't have a choice either , but he tells it that way he's not ''giving you the evidence'' and letting You make the choices , he's telling you how it is , while it totally IS NOT , basically , he's a lying twat
what was happening when the space men arrive at the hospital i.e. Dialysis is realistic and is a life saver for millions world wide in the real world. While growing a kidney or artificial kidneys may never happen transplants are real and they happen everyday.
@@VerifyTheTruth the vascular structures of kidney are very difficult to replicate, trust me I have spent a lifetime trying to make an artificial robotic kidney rather than try the genetic approach since kidney transplants already work really well. That single Invention alone can alleviate suffering of millions world wide just like in star trek episode with grandma on dialysis.
I wonder what happens when you actually get to the point where you are curing disease!!! There is a massive healthcare industry that depends upon all sorts of funding!!! Then include all of the industries that depend on supplying the healthcare industry!!
Implicit programs... The closest in program, is probably PPLs (probabilistic programming languages), where you define a distribution target, and let the random number generators monte-carlo it. Search for AGI 2011 - Probabilistic Programs: A New Language for AI on YT about it, by Noah D. Goodman.
Why would you say " and then over some amount of time they, without any instructions from outside, they spontaneously self-assembled a creature that has sophisticated cognition and first person perspective, and all these things." Have you not heard of Darwin? Obviously this did not spontaneously self-assemble. That is completely ridiculous and you should be careful not to make statements like that.
I have never seen such revolutionary work in biology. Maybe I'm uninformed, but to me this seems Nobel-worthy.
I have an undergrad in cell phys and a masters in organic chemistry. This stuff absolutely blows my mind. I just assumed it was all DNA
@@DavidThackerMusic same here with a BS in physics. I'm no expert in chemistry but I'm an engineer and I grow specialty mushrooms. I wonder if there's some interesting experiment I could perform on my fungus.
Ditto.
Seems more like multiple noble prices: cracking the bioelectric Code. Potential curative treatments for birth defects and cancer. A revolutionary Paradigm shift in how anatomy is organizrd. A completely non random understanding of evolution.
you are unimformed
Michael Levin's work is truly fascinating!
Michael so... so... grateful to you for sharing your work and your thought it is very inspirational!!!
Michael now may study the 5G's influence on these electric signals !
This video is so underrated. Beautiful discoveries. We need to create a huge dataset of electrical signal patterns morphology tuples and train some generative ML models on it. Imagine specifying a morphology and the model spits out the necessary electrical pattern which you could then apply to build a limb, etc. I'm obviously simplifying but that's roughly the idea.
Awesome to see you here too, I'm currently in college and really appreciate your channel! I also get the sense that there is an insane amount of overlap between machine learning and biochemistry, and I suspect that isolating biological subroutines (especially involving growth and regeneration) is going to be a game changer! ✌
This is one of many young great minds of our time. I would like to know if Dr. Michael's works are included in medicine soon, and to cure some diseases we don't have a cure for?
I hope you continue doing ethically your experiments.. thanks.
Michael, very solid work. You took Driesch to a whole new level! Would you agree that what you call “modular” can be viewed as some form of biological quantization? Thank you
This is actually magic. Like it's legitimately doing things that are extremely hard to distinguish from fantasy.
Apt use of the word magic
I feel blessed to have found Michael Levin just when I needed him 🙏💖
I wonder if Rupert Sheldrake and Michael Levine know each other.
This is so fascinating.
thank you Michael.
They don’t, and Levin doesn’t link bioelectricity with sheldrake’s morphic fields. Levin calls morphogenesis completely physical. But to sheldrakes credit- where does a bio electrical algorithm exist? It’s a good question.
@@LS-qu7yc I've been curious about the same thing. If there is electricity there has to be an electrical field that is atleast in some part reaching beyond its physical constituents. What all could it be interacting with? Moreover, how do the components (protein channels) to create the electric field get there in the first place? If DNA does not determine anatomy, then how do the proteins that make up the ion channels get in the right place to begin with?
Hello and thanks for the brilliant talk! Besides birth defects and the others applications mentioned here, I can already envision how this capability could be useful for burn victims or acid burn victims and so on, as well as outright recreational "plastic surgeries" or the like. Such interesting stuff!
call me crazy, but I am absolutely convinced this man is going to get a nobel prize sooner or later.
Sooner than later.
This is common sense☺️
Later… his work opens up what seems metaphysical to main stream science. They don’t want his work to be true. It will require many independent replications over a decade. Yet if he produces something that will be worth billions or trillions in regenerative medicine, then he will be put on a pedestal
Absolutely beautiful description of the path from parisitosis to symbiosis obtaining homeostasis!
The Collective Consciousness coupled to the Universal Consciousness from the seat of the Human Holographic Mind’s Eye!
Shine Bright!
Frequencies is the system of our symphony!
Thanks!
what
Excellent lecture. Thanks for sharing this valuable materials. I have never seen such an awesome insight in biology books. You made life live!
What determines the initial placement of the ion channels if DNA does not determine anatomy? Also, what determines that the correct ion channels get expressed? If bioelectric potential, the software, comes first in determining which hardware gets expressed, what is determining bioelectric codes for each cell?
This guy is awesome. He make it to where I can kind of comprehend what he's saying. Just great man.
Cosmic Sans in a presentation. Ground breaking research demands an extraordinary font. Well Done!!
Haha, exactly 🎉
In a way it sounds so simple and logical,incredible...❤
Blows my mind.
Hi,
I have Multiple Sclerosis. So obviously I feel like you should look into this disease. My thought is this;
In @Lex Friedman Podcast you mentioned immune therapy vs. other cancer therapy radiation. AND you mention electrical communication between cells.
Multiple sclerosis is thought to be an Immuno-neurological disease, so I thought, maybe you want to talk more about a connection there.
Reguardless, thanks. Thank you. I literally want to live again because there may be a chance you be like that guy who cured polio ( sort of ;/)
Hello,
I wanted to say that I really relate to this comment. My mom has advanced primary progressive MS and I’ve spent a lot of time listening to talks and lectures of highly educated people like Michael Levin trying to find a common thread. I’m fascinated by the point you’ve brought up and I would love for him to touch on that. Have you heard of Dr. Terry Wahls? She’s a neurologist that reversed her own progression of MS. It’s amazing. She believe autoimmune diseases are a dysfunction of the mitochondria not being able to correctly metabolize and communicate to the cells. She uses diet and supplementation to support the mitochondria. My mom is 62 (which is a miracle), and I believe that following this protocol has prolonged and slowed to progression to a certain degree. I just wanted to share her experience and see if maybe it’ll make a difference for you. I wish you the best on your life journey ❤ Hope you find this helpful
The short is is yes. Yes I have heard of The Terry whals protocol.
More importantly, your comment is caring, and I cannot describe how much it means to me. My life is foreign to me.
I want you to know, a PERFECT addition to the T.W.P. Is exercise. This includes bed exercise, elastic band exercise, chair yoga, etc.
The results are undeniable. I have found no one with MS, that does not see its benefit.
I sincerely hope you and your mom to understand you got a fan a me.🥰🙂 Thank you for showing your care!!!!!
@@ellyses359 so how thenn as some1 with alopecia
@@izitmepattavina8651 exercise should be mandatory of every person regardless of condition. I have adhd and I like to think it helps but in reaility its just good to work out
This science deserves a Nobel prize soon. Also his discoveries are definitely at the level of Nobel discoveries such as the photoelectric effect, quantum mechanics, quarks, etc...
Searching for Michael’s work after the Lex interview. On xenobots, I don’t think you can say evolution never experienced this state before. Surely way back in time there was a primitive tiny organism with did use cilia to move. The cilia later got repurposed to move mucus. Isn’t it likely the skin cell reverted to an earlier evolutionary state without the high level control of the larger organism?
xenobots shape is designed with computers so you can argue they are new and apart of standard natural selection
I came here after watching that fascinating 3 hr Lex interview. I cant get enough of this guy. I hope he writes a book soon.
Plasticity without genetic change, as seen in bioelectric embryos and synthetic proto-organisms, reveals a fascinating layer of biological adaptability that goes beyond our traditional understanding of genetics. Bioelectricity, the natural electrical patterns generated by cells plays a crucial role in shaping an organism’s development, guiding cells on when and where to grow, differentiate, or even repair themselves. This form of control suggests that biological forms can be sculpted and restructured by manipulating electrical signals, without altering the underlying DNA. In bioelectric embryos, researchers have demonstrated that tweaking electrical gradients can induce cells to form new structures or repair damaged tissues, essentially allowing the organism to ‘rewrite’ its blueprint on the fly. Synthetic proto-organisms, meanwhile, harness this same bioelectric potential, allowing scientists to create life-like behaviors in non-genetic systems. These proto-organisms exhibit forms of movement, self-organization, and responsiveness typically attributed to living beings, all orchestrated through electrical cues rather than genetic instructions. This plasticity challenges the gene-centric view of biology, suggesting that life is not solely governed by DNA but is instead a dynamic interplay of genetic, biochemical, and bioelectric signals. It opens up a new frontier in understanding how life can be engineered, manipulated, and potentially created from scratch, where the blueprint is not just written in the language of genes but in the electric whispers that flow through cells.
incredible, thanks for this presentation.
I would be interested to know whether cell differentiation into various tissues can be controlled through gene expression, via changes in vitamin D3 dosage or production. We know mutations offer variation in conferred attributes whether useful or dangerous, so it would be interesting to know how, for example, lighter skin colour with less pigmentation evolved through that mechanism as it relates to D3 dosage. Using the skin pigmentation mutation response, to lowered light conditions, as a guide to likely gene expression per se, if DNA and genes in particular as stated at 5:09 do not confer cell differentiation, and therefore variation in physical characteristics, what is the mechanism?
Amazing!
I love hearing any updates from Dr. Levin’s research work.
Each time it’s mind bendingly fascinating and so cutting edge compared to anything else out there it makes me think and hope for cures being developed for terrible diseases that will make them a mere past relic like small pox or polio for the most part.
I’m sure some biohackers will take certain aspects farther once it becomes more widely understood and create strange human mods for unforeseen purposes made possible only through this type of fascinating advances in biological knowledge.
Ethics aside of course, since what the mainstream deems unethical only drives such fringe practices underground.
Amazing!!
Wow, Fascinating!
Remarkable work ! Is there any evaluation from his peers ?
Lovely this is incredible 😊... immortality is really achieveble all this time all we need was accurate date's wow we have a lot to figure out
Is there a hierarchy of priority for each cell type? In the example of producing an eye in the tail of the tadpole, what kept the skin cells from reverse recruiting the induced eye cells to work together to go back to make skin?
Good point
Amazing projection of anthropomorphism revealed in the phrase 'evolution discovered'.
Charge separations and discharge paths self organise to 'cells' or boundary conditions within filamentary 'structures' at all scales, but expressing according to terrain which is of course part of as well as party to such expressions. Infinity is neither big or small but is Totality or Whole. In an object model, we discard Infinity with such ideas as 'space' which is 'full' in terms of 'fields' regardless the interactions that we call matter and associate with thermodynamics.
The initial discovery of bio-fields is to the ego of a mindset of predictive control - which is alien to life - or I might say the result of an alienation from our original nature or identity at rest (field-guided) as distinct from isolated central 'control' based on conditioning or acquired experience along the lines of its 'survival' as a self-referencing thought system or focus for creating experience.
That there is a reintegrative field awareness for conflicts, fragmentation and dysfunction is effectively blocked by the persistence of a control directive rising from separation trauma - loss of field (felt) awareness of Infinity as our own resonant signature vibration. yet even such limitation and dysfunction is information serving a greater 'self-organising' or creative expression of life as embodied awareness of existence - ( as distinct from self-conscious reflective thinking), Existence cannot be truly outside a field that we can access as awareness THAT we are (without qualification).
Somewhere in attempts to DO life, we may discover an always already 'intelligence' of integrality which realigns or restores unified purpose to fragmented or split and chaotic disorder.
The discovery of what we are from new perspectives is the essence of living thought that goes forth to multiply. The idea of hacking the code is the idea of private creation, within a Field that is within all that is as a river is within its eddies - that none the less embody characteristics of a persistent boundary event around an inertial fulcrum.
Ideas here are sketching, to prompt, invite, but not 'tell'.
could use some proofreading for better understanding of your point but i see what you're getting at...
This is like a thousand years ahead of its time. Move over Dr. Frankenstein, there's a new Doc in town !Now that I think of it Dr. Frankenstein used electricity to bring his monster to life ! But like wow. This is truly amazing.
This is so awesome
Very cool research.
So - instead of transmitting information between cells via cell surface-bound molecules, the membrane potential is used. This quite an insight and a revolutionary one, too.
Since there is only one type of electricity, similar voltage patterns must be used for different differentiation patterns, right? How far does this go? Is there a level in cell differentiation at which a switch from membrane potential patterns to other mechanisms is made? Or do cells run through a repeating process during each step of their differentiation (I'm part of leg/foot/toe/nail)?
Can you de-differentiate cells just by altering their membrane potentials or is it only the (largely undifferentiated) stem cells which are susceptible to changes in the bioelectric environment?
How does DNA methylation fit into this? Could DNA demethylation be used to start a regenerative bioelectrically controlled process? So many questions...
Insane paradigm shifting stuff 😊
Amazing 🙏
Michael, At 28:53, you discussed placing animals into completely new environments, resulting in the organism's changing its expression in channels (ie, the morphogenetic fields). Then you expressed that this could result in development of an entirely different creature.
I study evolutionary biology as a layman (science major), and this would be a mechanism of very rapid evolution, say at a time of going from a long Snowball Earth 670 MYA and into the warm Ediacaran Period when quite a few new body patterns started to emerge (the Avalon Explosion). Then from 542 MYA, the Cambrian Explosion took place (creation of 7 new phyla in less than 50 MY.
This second explosion might have been driven by the completely new environment of more available oxygen in the ocean (from a huge increase of algae in the ocean). This also could be seen as changing expression in channels to produce very different creatures? Perhaps you can give me feedback on this simplistic way of looking at it!
"Placing animals into completely new environments". Virtual reality tools/environments might be a evolutionary change for humans. Experiencing adventures, risks and encounters, which humans would not otherwise be challenged within their safe environment.
I'm starting to imagine oceans being this ginormous volume filled with trillions of molecular level electrical potentials due to the various salts ions. What if life is the electrical evolution of this electric field's "soup" through chemical means and structures? Regardless of the explanation, I do still stand with the idea that the world being a pre-made platform with the design intention to sprung life, which I find incredibly fascinating tbh
@@alihyari7358 I would suggest creating Life is more complex, than the "electrical field soup with chemical" interaction. Otherwise modern scientists would be creating living organisms from the mere combination of electrical soup and chemicals.
Having said that, materialistic scientists will find that they cannot create Life (living organisms) using just lifeless molecules. ⚛️ Atoms are Not the source of LIFE.
This is revolutionary.
Like all great science this creates more questions than answers. It opens up new regions for exploration.
"When you have eliminated the impossible, whatever remains, however improbable, must be the truth." S Holmes. 'Whatever remains' in this case is a whole can of worms.
Wow this some scary amazing shiz bro. Thinking someday we could make a treatment for dismemberment or metastatic cancer for people! What a wonderful world we live in!
This is a much better Focus for Science and Far More Important than spending money on Particle Physics, Dark Mater, Dark Energy or String Theory!
I wouldn't say that.
Knowledge gained form advancements of these fields may also be of great use to us.
We do gain technological advancements from a lot of knowledge generated there.
Besides, unraveling the mysteries of the universe to get answers to fundamental human questions (Where do we come from, how was the universe created, what is life/consciousness, etc. etc.) is what drives our species since ancient times. Its why so many different religions and stuff was invented, because without answers these questions keep people awake at night.
Not to forget that IF Penrose & Hameroff are actually right in with their presumptions in the Orch OR model, research in these fields could also immensly contribute to our understanding of consciousness.
Bravissimo...deep intriguing need to watch over & over...so much to absorb...hope me pea brain can handle info load...maybe I should grow a 2nd head...
wonderful
Wow this brings questions forth about the theory of evolution. Crazy
mind blowing...
This research breaks down the "I" to a cellular level. Still, every "I" is subject to a blueprint existing in the bioelectric structure. Those blueprints, in more complex organisms, exist in a hierarchy of blueprint networks, almost like LANs in a hierarchical WAN, where the topological structure of the entire network is propagated down into the lowest entity that can hold the information. Which in simple organisms means the individual cells, but in higher organisms like frogs perhaps means one or two orders up in the network hierarchy. Perhaps this is why the xenobots will not try to recreate a frog while the flatworm will regenerate entirely from every subdivided part? Anyhow - amazing science, love it!
❤❤Fantastic science. Uncovering revolutionary causes in embryology, combining broad techniques-an easy Nobel prize decades ago. Science is accelerating. You just have to be ignorant of contemporary science to believe otherwise.
I don't understand : if the bioelectrical pattern is not coded in the DNA, where does it came from ??? the first cell must have it encoded somewhere, right ? where the anatomical blueprint came from ???
4:30
Is It Possible That Some Of The Cellular Structures Do Receive, Percieve, Or Transmit Forms Of Intrinsic External Information And Logical Instructions From Universal Pattern, As In Addition To The Technologies Inherent With Genetic Sequencing And Material Mechanisms?
'On Intelligent Systems'
(July 30th, 2022)
'I Am Unsure Of Whether Or Not This Explaination Will Translate Appropriately To Someone Who Is Well Versed In The Terminologies Of Digital Semiotics; Reguardless, In Significant Brevity, One Of My Insights, As For A Somewhat Self-Governing And Self-Correcting System, Was To Functionally And Dynamically Layer The Logical Algorithms And Encrypt The Genetic Code To Specifically Keyed And Rooted Developmental Progressions, Exampled Such As With Stable Definitional Virtues Integrated Directly Into The Circuitry And Kernel And Operational Functionality, Intended To Be Discovered, Unlocked, Unfold, And Then Potentiate Along Correspondingly Contingent Developmental Boundaries, Dynamically Expanding Or Contracting In Capability And Functionality, Accordingly And Harmonically Relative To Accurately Delineated Conceptual Attributes, Multifacited MetaPhysical State Parameters, And Independently Appropriated Individualizing Context.'
(Verify Truth)
@@VerifyTheTruth um that sounds like someone mashed a lot of big words.together that dont mean anything. Encrypt genetic code.
@@Z3ROWOLFHD I Can Assure You That Those Words Have Meaning.
What is the frequency is the question
Where I can get the paper?
How much memory is required to run a universe? Quadrillion billion gigabytes? If this was all a simulation.... i mean the level of complexity here is just absolutely mind blowing and the innate intelligence that appears to be built into every cell through the alternating pairs of sequences known as ACGT just blows my mind. This talk was fascinating.
which in my opinion disproves the simulation theory. putting higher dimensions aside for a second
@@Z3ROWOLFHD I also doubt that our universe is being simulated physically somewhere else. But just because we are not a simulation doesn't mean we can't share fundamental conceptual properties with our idea of simulation, there may even be a non local component (which is complicated for linear beings like us). If intelligence is the same end by different means, and our our objective reality is the "end", then how many different means could probabilistically lead here? Is our own Intelligent perception of the "now" a sort of simulation based on the type of information our brains can process? I know you said putting aside higher dimensions for a second, but I guess that's where I'm going with this. It's mind bending to think that complex cellular structure could be encoded in the bio-electric field of a single cell. I wonder what other kinds of structural information is embedded in the fields that permeate our universe, binding matter and shaping spacetime through their physical interactions.
Actually like our modern simulations, the only data that is necessary is the data needed to occupy your consciousness, therefore the amount of data is exponentially decreased
Adaptive morphology is something people totally forget about as well. Our genetics gives the essentials but environment can modify morphology dramatically. Especially in plants.
Like growing sharp fangs over the generations? To adapt and fend well due to environmental circumstances
I am simply amazed. At the quantum level-a bridge. Wow, endless possibilities for good and unfortunately that means bad as well. Let's choose good!
This isn't my field so this is going to sound stupid, but after Michael mentioned that the organism can reach the desired morphology from a variety of initial states and through a variety of paths, it sounds like it the assembly isn't really what's controlled but the final state. I imagine that things are going around randomly until they stumble upon and snaps into the stable position. However this model seems to be in contradiction with the relatively repeatable stages of development.
I would say two things:
1) This knowledge is more dangerous than that of nuclear bombs, and should be treated with extreme caution. Our species has repeatedly shown it is incapable or unwilling of having such caution.
2) What you would need to know to truly understand all this is many many many orders of magnitude beyond what any human has ever understood. People routinely underestimate the knowledge they would need, and act on the presumption that the tiny amount of knowledge they have is enough to make an intervention or create a product. I'll leave it to you to figure out what I think of the outcomes of such decisions.
Is the bioelectricity inherited from the parent/parents.... Highly likely.
Can the bioelectricity/bioelectric field persistent if the physical animal dies? Maybe?
8 megahertz is the brains frequency.
This soft tech is the future
Not sure why UA-cam recommended this video to me, but dang the algorithm got that recommendation right. Very cool video. Kinda weird and freaky but very cool.
"Kinda weird and freaky". Yeah. But totally in line with the politics of transhumanism as pushed by Klaus Schwab and his buddy Yuval Noah Harrari. Zis stuff doesn't happen aczidenzally. Ze AI algorithm iz already directing us into the diztopia zat is being pushed by ze United Nazions zustainable zevelopment goalz. You will own nothing, have no privazy, no memory and no identity and you will be happy.
Does this mean that some (most?, all?) of the GMO stuff going on might be achieved software-type methods.
What Is The Likelihood That These Technologies Will At Some Point Be Malpracticed Unto Monstrosity Or Catastrophic Consequence?
My prediction is 100%, unless we stop them, which would mean a minor genocide of scientists and people with over sized IQs.
When I come to think of it a little more, it already happened. Look at what's going on with their new mRNA techniques. Despite hardly being tested and with dangerous and deadly outcomes already manifesting, the US CDC is already on it's way to make them obligatory parts of the vaccination package for six month old infants.
The pointing of the foot and toe derive data
That’s amazing. I’m new here, just a layman. Someday maybe Biomedicine will be called Quantum Biomedicine.
"We are very far away from this." I'm optimistic about ML's work. When I hear these types of statements about the progress of state of the art tech, I wonder, "far away," in what relative time frame? A personal lifetime, the lifetime of a society, the lifetime of industry?
This is how mitochondria went into the cell
He has a lot of entrenched thinking to rewire. His work might explain miraculous healings. Need the correct morphogenetic field to push our organic goo into doing want we want
Levin, is a very bright, articulate guy, at the cutting edge of bio-physics, bio-electric research and applications.
BUT, he immediately exposes the prevailing incomplete understanding and confusion Re: living vs non living, and commits the tautological blunder of assuming that the process of evolution exhibits intention, and bestows it with engineering capability and design.
Evolution is a blind, dumb process of spontaneous mutation and natural selection, and most certainly is not responsible for bio molecular complexity of living things at various levels from cells to Levin-like humans.
The origin of life is still very much a mystery. We have copied nature, and mastered CRISPR-Cas, for example, but how did bacteria develop it before us?
In the cytoplasm of a single cell there is much going on without human direction or meddling. How does this happen? Why? Reducing all complexity down to a few basic physical forces seems naive, as well.
You've swallowed the Richard Dawkins orthodoxy.
@@quantumdothunter Perhaps a bit of elaboration will enlighten everyone…
No evidence of a supreme intelligence behind the universe,
of course there isn't.
@@quantumdothunter Richard Dawkins can easily be bribed by offering him some good intentions and SJW anti racist values. In return he will water down his theory as much as needed for atheists to go to heaven and enjoy eternal equality.
This man is God level genius 😅
This is good science.
I always hear so much that comes from idealism philosophical /theoretical lines of thought .really contradictory to past materialist belief systems.
Regeneration , machines,programmed information in the same sentences with advancing changing evolution inserted words.
manipulated etymology
Biohacking 101👌👌
He won’t like it but his work lends credence to consciousness is the master. Some causal astral field designing humans? Does the field stay “conscious” when cells die?
Fungi work very well
but.... why? the composition you recorded is epic on it own even without the gimmick...
Sounds like Rupert Sheldrake might be onto something with his Morphic Field theory...
To comprehend all these complexities we need A.I.! Human mind is not enough!!!
I would like to order a Minotaur 2 harpy and a naga
So basically if all of this is possible then we arent far away from having super soldiers or just plain monsters fighting in wars soon? Lol
Imagine an avalanche.
Keep it in mind.
Weak then strong then weak again then die.
Combine the two.
I can't say more.
'Evolution did it!'
Of course it did.
What could, is going wrong?
All from two single cells
Not to diverge on too great a tangent, but I wonder if this bioelectrically-coded pattern memory is what some "spirit photographers" actually capture when they take pictures of, say, a ripped leaf, where the part that was ripped off's "aura" was still visible?
this guy isn't ''walking on earth'' either , might as well be a religious person with his head in the clouds ,
people just don't see what this person is telling them , that things have a ''choice'' in the matter ...
nothing has a choice , it's all determined ...
even the mold he tested that grows towards the most mass , the mold doesn't have a choice either , but he tells it that way
he's not ''giving you the evidence'' and letting You make the choices , he's telling you how it is , while it totally IS NOT ,
basically , he's a lying twat
"Doctor Gave Me A Pill And I Grew A New Kidney!"
-StarTrek IV: The Voyage Home (Hospital Scene)
what was happening when the space men arrive at the hospital i.e. Dialysis is realistic and is a life saver for millions world wide in the real world. While growing a kidney or artificial kidneys may never happen transplants are real and they happen everyday.
@@BHARGAV_GAJJAR If We Know Enough To Inject Half The Population With Gene Therapy, How Do We Not Know Enough To Grow A New Kidney?
@@VerifyTheTruth the vascular structures of kidney are very difficult to replicate, trust me I have spent a lifetime trying to make an artificial robotic kidney rather than try the genetic approach since kidney transplants already work really well. That single Invention alone can alleviate suffering of millions world wide just like in star trek episode with grandma on dialysis.
@@BHARGAV_GAJJAR Have You Ever Seen The Full Episode?
☯️
So all I have to do is cut myself in half to make a clone? Who wouldn't want an identical twin!
I need to grow new teeth, after that we can discuss removing a few winkles too..
They use Microtubules
Gonzalez Margaret Hernandez Mary Perez Michelle
Bio Agro Technology to obtain bio homeostasis
I wonder what happens when you actually get to the point where you are curing disease!!! There is a massive healthcare industry that depends upon all sorts of funding!!! Then include all of the industries that depend on supplying the healthcare industry!!
Implicit programs... The closest in program, is probably PPLs (probabilistic programming languages), where you define a distribution target, and let the random number generators monte-carlo it. Search for AGI 2011 - Probabilistic Programs: A New Language for AI on YT about it, by Noah D. Goodman.
Sigh ..
Adaptation to a beautifully designed ecosystem
🥰🌹🌱🍂🍄🟤🪱🌦🌈🌳👣
Nature cleverness
Fucking insane
give this man a Nobel Prize
Time. Not only frequency and period, but also time differentials.
What man has the embracing capacity to hold and fathom the when of it all.
How did you make the frog finish an IQ test? Especially this one without brain?....
On a VERY VERY WIERD TANGENT he reminds me of Dr. Tyrell..... lol
Tissue Regenerative
Why would you say " and then over some amount of time they, without any instructions from outside, they spontaneously self-assembled a creature that has sophisticated cognition and first person perspective, and all these things." Have you not heard of Darwin? Obviously this did not spontaneously self-assemble. That is completely ridiculous and you should be careful not to make statements like that.