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The Truth About the Gut to Brain Connection

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  • Опубліковано 13 сер 2024
  • There aren't many bodily connections as powerful as the gut to brain connection. Why? Watch this new episode of SciShow hosted by Olivia Gordon to learn about the immense power of the microbiome!
    Meet your Microbiome: • What Your Microbiome D...
    Hosted by: Olivia Gordon
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КОМЕНТАРІ • 1 тис.

  • @weeliano
    @weeliano 4 роки тому +76

    I suffer from anxiety related stress and I find taking Bulgarian yoghurt helped tremendously in stabilizing my mood and anxiety. I believe there is a strong correlation between the mind and the gut biome.

    • @iloveplasticbottles
      @iloveplasticbottles 2 роки тому +4

      That or you're experiencing the placebo effect. I'd try regular, non-bulgarian yogurt without knowing thats what you're eating.

    • @evatsaneva8202
      @evatsaneva8202 2 роки тому +5

      From what I know, there are good studies documenting the effect of Lactobacilli on the physical health. I don't know anything about mental health in relation to the bacteria, however, Japan has tried to 'copy' and be able to implement the bacteria in dairy products who lack it. As a Bulgarian myself, I am happy there is someone who is aware of its benefits, and I suggest that more research is definitely needed.

    • @helenamcginty4920
      @helenamcginty4920 2 роки тому

      @@iloveplasticbottles Maybe Bulgarian yoghurt is the same as Greek yoghurt? Maybe it is live rather than pasturised to death? I dont know but it would make a difference.

    • @Qliphirot
      @Qliphirot 2 роки тому +2

      @@iloveplasticbottles gaba is produced in the gut so if he has a low gaba deficiency his body won't be able to tolerate stress and it'll lead to anxiety symptoms

    • @savesoil3133
      @savesoil3133 Рік тому

      Hi there!
      Since you are interested in food:
      It is said that by 2045 we would be producing 40% less food than what we are producing right now and our population would be over 9.3billion people. #nosoilnofood
      We can take action now and turn this situation around, and create a significant change. #SaveSoil #ConsciousPlanet #Mentsükatalajt #Tudatosbolygó
      I thought it's important to share🌿
      Love from Hungary 🌏🌎🌍

  • @WoodChoppa911
    @WoodChoppa911 6 років тому +101

    When someone say "my gut is telling me ....", that means that their gut were actually telling them

  • @XxFreako64xX
    @XxFreako64xX 6 років тому +55

    Literally 3 1/2 years ago I had to go to a doctor because I was severely ill. He doesn't go through insurance because he really tries to get to the root of the problem. He found out my whole GI tract was inflamed and I had horrible IBS (while my other dr just said pretty much that's the way it is). When he told me that 80-85% of serotonin was made in my gut and could explain why I was so severely depressed and having over 10 panic attacks a day. Once he worked on helping heal my gut- I honestly had hope again. I thought I was dying and there was no way out of the mental hell I was in. By the grace of God. I am doing so much better. And honestly, could be doing even better. I just need to be more intentional. But he knew all of this stuff for years!! If you are not doing well. How is your gut?? I now don't eat gluten (inflamitory or milk) to keep the inflammation a bay. I know some people don't get this whole gluten then but trust me. If you have ibs, anxiety, depression, getting sick all the time-, there's a reason. Don't just let a doctor give you some pills to manage it. Dive in and find what's the problem. There's hope! I will share this with who ever because I know the mental hell and physical pain and how hard that was.

    • @romeoromeo9651
      @romeoromeo9651 5 років тому

      Thanks for writing this.
      It helps me. M suffering from anxiety nd don't know how to deal with it. Doctor advised for yoga nd meditation. I will be thankful if you can suggest me some thing to cure it. (Sry for poor english)

    • @MapMonkeyTube
      @MapMonkeyTube 4 роки тому +6

      Could you elaborate on the "helping heal my gut" part beyond removing gluten? Diet changes? Probiotics? It is not something you covered in your post and I'd like to know more.

    • @moremerry57
      @moremerry57 4 роки тому +3

      Romeo Romeo, are you saying the doctor prescribed NO meds to help with the attacks?!? That is incomplete response to your problem. Yes, yoga and meditation are good ways to fulfill the exercise part, and diet IS important. But unless these have eliminated your problem, you should have meds to carry you through attacks.
      I should mention that I used mine as a last resort, and was able to calm myself when an attack began in part by knowing tat the meds were on the cabinet if I needed them. Consider asking your doctor for fallback prescription.

    • @Player500-1
      @Player500-1 4 роки тому

      TMI but was one of your symptoms a very loose stool 👀 (asking for myself)

    • @mohammeduddin7082
      @mohammeduddin7082 5 місяців тому

      Xxfreak054xx what is the name of the doctor you went through

  • @Master_Therion
    @Master_Therion 7 років тому +745

    1:47 The Vagus Nerve connects the ENS to the brain? So, what happens in Vagus doesn't stay in Vagus.

    • @SeaMower
      @SeaMower 7 років тому +60

      I haven't got the vagus idea what would happen.

    • @sacr3
      @sacr3 7 років тому +38

      Not enough information, its too vagus

    • @CAPSLOCKPUNDIT
      @CAPSLOCKPUNDIT 7 років тому +9

      Only if your "second brain" is the one in charge .

    • @umm_rit_
      @umm_rit_ 7 років тому +3

      you win

    • @Joxman2k
      @Joxman2k 7 років тому +4

      What happens in Vagus stays in vagus :)

  • @ItsMe-ox8lm
    @ItsMe-ox8lm 7 років тому +89

    This is one of the best videos! It is very interesting, when she talked about how a shy mouse can change its behavior, just by changing the bacteria in its gut, that groundbreaking to me. Thank you Olivia!

    • @wiameena39
      @wiameena39 7 років тому +4

      :) In real life that's so logical. When a person is hungry even if they are shy, they might go ask other people for food or just find them self surprisingly more out going to a point where they might "find them self" stealing food sometimes (it's not an excuse tho). Scientifically it's all gut bacteria!
      What i wonder about now : does any kind of bacteria interfere when people are scared, hopeless, traumatized, happy, ... even when they are not hungry?! in other words can the emotional state or even the personality of a person be related to it's bacteria?

  • @bengarcia2074
    @bengarcia2074 5 років тому +38

    Remember that old saying....
    "You are what you you eat"
    Healthy food, good excercise, good friends, and love self. Keep it simple!

  • @mahenonz
    @mahenonz 7 років тому +20

    I was completely cynical about this "your gut can affect your brain " theory until a recent bout of food poisoning. I felt perfectly fine after 12 hours or so - except I had zero interest in food which lasted several days. My doctor said my stomach needed a "reset" and probiotics did the trick. I was amazed how much an illness could completely change my thoughts.

  • @PfEMP
    @PfEMP 7 років тому +112

    Research on microbiomes is really hot right now, they seem to have an impact on basically everything

    • @johndough23
      @johndough23 4 роки тому +1

      @N K Her early diet failed to turn-on the usual sexuality genes. This is very common these days of GMOs and pesticide food consumption. It is WHY the entire gender confusion expression we see in the news. This is new and not something which was hidden by a tyrannical system run by Charlton Heston and Ronald Reagan. We do have millions more severely screwed up people with gender issues now because of a crappy food supply. The bugs who benefit don't want us changing this in fact the opposite.

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 3 роки тому +3

      It really is. Did you know that changing what you eat can change your gut microbiome in just 2 days?

  • @shreddermcscumbag9755
    @shreddermcscumbag9755 7 років тому +23

    I think Naturopathic doctors can have some very misguided views at times, but in this situation I've seen that they definitely have a point. Many have been pointing out this connection for decades and "prescribing" remedies for stress through this medium.

  • @em0860
    @em0860 7 років тому +47

    I am so glad you presented a video on this topic - As a microbiologist suffering with Ulcerative Colitis, I find this to be a highly important subject and the explanations you give are more than relevant to my dissertation. I cannot wait to see how what I learnt about stress and the microbiome affects later studies :)

    • @michaelroy6046
      @michaelroy6046 5 років тому +3

      glad to not be a fecal transplant recipient mouse

  • @julia393n
    @julia393n 7 років тому +34

    Didn't Hippocrates advise us "Let food be thy medicine and medicine be thy food"

    • @SunnyDeeTee
      @SunnyDeeTee 4 роки тому +6

      And he also said, "all disease begins in the gut."

    • @allisond.46
      @allisond.46 4 роки тому +4

      And he also said, "What's for dinner?"

  • @64standardtrickyness
    @64standardtrickyness 6 років тому +30

    so I CAN fill that hole in my heart with food I just haven't found the right food.

    • @moremerry57
      @moremerry57 4 роки тому +4

      64standardtrickyness, I know you mean to be funny, but people will agree w/you out of loneliness. You can’t fill the hole w/food; you have to switch your focus away from the hole. Focus on a fuller life - that will start to close the hole.

  • @ejlerthomsen
    @ejlerthomsen 7 років тому +23

    For the last two years I have had a dysbiosis, Small intestinal bacterial overgrowth. During that time I have been treated with antibiotics twice which has let me perceive at least 4 drastically different gut microbiomes. I have a first hand perspective of drastic mental changes that accompany changes in human gut flora. In the last two years I have felt some of the worst forms of mental illnesses from being suicidally depressed, to crippling anxiety that caused me to become agoraphobic. I have been able to treat all of my symptoms of SIBO, including the mental, with a short dose of antibiotic and long term probiotics. To me it is no question that the human microbiome is at the central cause of everything from IBS, to many mental illnesses. It is my belief that dysbiosis are getting more prevalent due to the increase in consumption of highly ferment-able foods and the widespread use of antibiotics.

    • @ejlerthomsen
      @ejlerthomsen 7 років тому +3

      Margaret Thatcher I used what's called a low fodmap diet to find what foods I can eat. The diet was at first very restrictive of fruits and vegetables. As I progressed I found that pretty much only wheat and corn are the main irritants to my gut.

    • @Alexandriafrancescakiel
      @Alexandriafrancescakiel 4 роки тому +1

      Iron Manatee I’m sorry you had to go through that. I hope you are doing better now. I too had to go through two rounds of strong antibiotics and I literally could feel myself becoming more and more depressed everyday. Hopefully doctors start to listen to us.

    • @Qliphirot
      @Qliphirot 2 роки тому +1

      Very interesting.

  • @kiwiboy1999
    @kiwiboy1999 7 років тому +237

    This really does give some alarming concerns for how various antibiotics can severely damage your mental health.

    • @MacCoalieCoalson
      @MacCoalieCoalson 7 років тому +9

      kiwiboy1999 ...not really.

    • @rincewind304
      @rincewind304 7 років тому +15

      Not really, at all. The antibiotics we take have minimal effect on our microbiome for many reasons. A major one being that the microbes we don't want usually have a different make-up than the ones we do. We also have so many of the good microbes that any damage to their numbers is quickly repaired.

    • @kiwiboy1999
      @kiwiboy1999 7 років тому +31

      I have one response to that; we apparently had no idea that the intestines, and the microbes within, had a large impact on mental health and general mood. it'd be foolish to rule out us simply not knowing the potentially damaging effect you'd expect from killing microbes.

    • @amicableenmity9820
      @amicableenmity9820 7 років тому +21

      Eh, it depends. There's a lot of antibiotics that can give you a C. Diff infection because the good bacteria were killed too.

    • @rincewind304
      @rincewind304 7 років тому +6

      But if we have never measured a noticeable mental effect from antibiotics. Why would it suddenly start being an issue?

  • @lisaoldwithsomanywhys5487
    @lisaoldwithsomanywhys5487 7 років тому +4

    My grandmother worked for a "resort" in Genova, Italy back in the 1950's where the "rich & famous " would go for a few months to completely cleanse their gut & mind✌🏻👏😱

  • @OswaldDigestiveClinic
    @OswaldDigestiveClinic 3 роки тому +9

    Great video! To add to this, nutrition issues can result in anxiety. For example, magnesium deficiency can be a problem. This deficiency may result from our soils being depleted of magnesium, the increased amount of magnesium used by the body during stress, medications like birth control, and not eating enough magnesium. One good food source of magnesium (and delicious) is pumpkin seeds!

  • @naarad_muni9440
    @naarad_muni9440 2 роки тому +10

    I’m so glad I took Ayurveda as my way. The Ayurvedic concept of food affecting mental state (Satvik, Rajsik and Tamsik food) is just one among many things which are now making complete sense to me.

  • @BRUXXUS
    @BRUXXUS 7 років тому +12

    This is really interesting to me, especially as a guy who's had ulcerative colitis for about 10 years now and has struggled with depression for about the same time frame. UC sucks, but UC AND depression make a pretty brutal combination.

  • @rgrateful
    @rgrateful 4 роки тому +3

    Stress causes illness, resistance in life causes the body to go into fight or flight. When discernment kicks in. Use it! It's a message from the brain to protect you..... If you live in truth, you'll do what is right, and your gut will flow...and your immunity will be most healthy....live in truth for a healthy life.

  • @EmoPurpleTurtle17
    @EmoPurpleTurtle17 7 років тому +214

    Does this mean people with the lactose mutation could have different brain chemistry to people without the mutation?

    •  7 років тому +18

      Nice thought!

    • @liquidminds
      @liquidminds 7 років тому +62

      Even worse. Proof that Vegans actually have a different brain than regular humans!

    • @Notlordstark
      @Notlordstark 7 років тому +53

      Yes actually, that's possible. I've been working in a feeding behavior-based neuroscience lab for some time now, and the gut-microbiome-brain axis is one topic we are currently exploring. The lactose mutation would cause there to be an increase in sugar availability for those microbes that can metabolize lactose, giving them an advantage. Larger colonies of those microbes could affect the chemistry of the enteric nervous system. (By-products of lactose metabolism could also play a role; gas production in response to lactose availability for example could give a separate species a carbon source). It's an extremely complex system and literally any changes can have an effect on the entire system as a whole.

    • @seanpeery7780
      @seanpeery7780 7 років тому

      Sarcastic dog whistle. Props.

    • @DocESARobsidianbruk
      @DocESARobsidianbruk 7 років тому +9

      Wouldn't the pressence of lactase in the gut deprive the microbes that metabolize lactose of their sustenance, putting them in a Disadvantage?

  • @TodayIFoundOut
    @TodayIFoundOut 7 років тому +272

    Super interesting :-)

    • @willynebula6193
      @willynebula6193 7 років тому +12

      one channel watching another channel.
      mind blown!

    • @stardreamer8996
      @stardreamer8996 7 років тому +5

      Rare, don't steal.

    • @tehgendo
      @tehgendo 7 років тому +1

      original character doughnut steel.

    • @bunbundabunni3843
      @bunbundabunni3843 7 років тому +9

      You should make a video on Toxoplasma gondii and all the weird research into it!

    • @thecrazyisreal
      @thecrazyisreal 7 років тому +1

      I always thought it was the Vegas nerve. Today I found out that I'm a moron.

  • @calebcross3894
    @calebcross3894 4 роки тому +6

    I’m on Antibiotics and Antidepressants, your video is scaring me

  • @MakeMeThinkAgain
    @MakeMeThinkAgain 7 років тому +9

    In medicine (and psychology) I predict this is going to be the century of the human microbiome.

  • @cosimodirondo6214
    @cosimodirondo6214 7 років тому +4

    I'm an italian medical student and I'd like to compliment this channel, your contents and divulgation efficacy are really amazing! Go on like this

  • @butterflyfx57
    @butterflyfx57 7 років тому +97

    What if kissing evolved as a means to colonize each other with microbiomes?

    • @followyourideas
      @followyourideas 6 років тому +8

      Mind-blowing

    • @chrisvaccaro229
      @chrisvaccaro229 4 роки тому +4

      it definitely transfers sex hormones

    • @allisond.46
      @allisond.46 4 роки тому

      Are you serious?

    • @BMN_Prime
      @BMN_Prime 4 роки тому +1

      If it was we'd all have ulcers

    • @johndough23
      @johndough23 4 роки тому +6

      Good point. I think it is rather naive to think any behavior we do is NOT being driven by microbial need. I think it is rather obvious the oldest parts of the brain are the ones responsible for the most basic of human functions. They house the original microbes. The pecky order flows from there.

  • @sbrodie99
    @sbrodie99 4 роки тому +4

    I’m here trying to build a case for a natural approach to treating my MS - by strengthening my blood brain barrier/improving my gut-brain microbiome. At the moment, I don’t believe I actually have MS. I believe that the antibiotic I was on for an infected finger crossed my blood brain barrier because it was weak, poisoning me and causing damage to some of the myelin and altering my body’s functions. Lots of natural approaches to treatment use blood brain barrier/gut-brain microbiome science. I’ve decided that this is the best approach for me because it means that I’m completely in control of my own “treatment” and won’t be opening myself up to unwanted side effects or risks. I *think* that MS, Alzheimer’s and other neurodegenerative diseases are actually results of weakened blood brain barriers/gut-brain microbiomes and that by finding ways to strengthen the barriers between the body and the brain, we can reduce or even eliminate the risks of neurodegeneration. I REALLY hope I’m right. Next month I’ll be telling my neurologist all this and hope that he will support my logic and my choice 😅

  • @plantpotshoes2644
    @plantpotshoes2644 7 років тому +103

    Does this mean by kissing someone you become more like them?

    • @59acres
      @59acres 7 років тому +106

      If you're kissing their ass,yes.

    • @TheFronkinator
      @TheFronkinator 7 років тому +24

      59acres specifically the anus

    • @adygombos4469
      @adygombos4469 7 років тому +20

      59acres Because someone eats your booty like groceries.

    • @Schradermusic
      @Schradermusic 7 років тому +11

      It means that if someone vomits in your mouth and you swallow it, you become more like them.
      So Rick & Morty got it right.

    • @duchessedeberne3909
      @duchessedeberne3909 6 років тому

      Bum

  • @hermanman8235
    @hermanman8235 2 роки тому +5

    Gut instinct/gut feeling really do have a basis in reality after all.VERY INFORMATIVE VIDEO.

  • @renze7133
    @renze7133 6 років тому +5

    In a video about the microbiome the channel What I’ve Learned made, he talks about how certain bacteria might cause autism. He tells the story of a kid who was developing normally, but after several antibiotics courses started acting weird and was later diagnosed with severe autism. Noticing a link between the antibiotics and the sudden autism, the mother dove into the studies and found that antibiotics could cause autism-like behaviour in mice. Antibiotics targeted a lot of bacteria, but not a certain bacterium which was also overly present in autistic children’s guts. So she found a doctor willing to experiment and gave her son a antibiotic targeted specifically at this bacterium and the autism in the kid slowly became less.
    I find it very interesting how much your microbiome affects your brain and how it could be the cause of a lot of mental issues. Another example: a transplantation of gut microbiome between two sisters led the receiving sister to become overweight like the other sister, even though she didn’t change her diet or workout schedule.
    Future research about this topic really could result in a lot of problems disappearing, it’s amazing

    • @EliteprosoldierMW3
      @EliteprosoldierMW3 4 роки тому

      Beautifully stated but the sci show will not look at or address this ground breaking discovery

  • @ProfessorPolitics
    @ProfessorPolitics 7 років тому +4

    For those who are interested in this topic, I'd recommend the book "I contain multitudes." I'm going through it right now and it hits on all of the topics in this video and then some (like, for instance, how cows and other rumanids need their microbiome in order to actually digest their food). It's also pretty fair about what evidence on the impacts of the microbiome are more "certain" or more speculative.

  • @pompey333
    @pompey333 7 років тому +2

    A possible use for this research could be future space travel in which some humans are almost germ free but that sounds like something we would need way down the line

  • @chrisboucher1987
    @chrisboucher1987 4 роки тому +2

    Explains why my depression isn't as bad now that I'm paying attention to my gut health... maybe?

    • @1878Devils
      @1878Devils 3 роки тому +1

      What did you do to change it? And how significant was the change

  • @workman88
    @workman88 7 років тому +20

    What if we aren't controlling us but the little city in us is.. lifeception

  • @amberkat8147
    @amberkat8147 2 роки тому +4

    Given that everyone in my family from my Dad on down- I don't know about his siblings or parents except that his mother had many of the same health issues I do- has IBS/food sensitivities/fodmap issues, this is a VERY important topic to me. If there's a way to tweak our systems so we react less to foods that would help all of us. Especially me, since I have the worst of it- the inflammation and blood sugar issues from our normal diets contributes to pretty much every health problem I have aside from the inability to sweat normally that my sister and I were born with. Anything that would let me lose weight, somehow fix the hypothyroidism, help me to get my blood sugar under control, make my mental illnesses less serious, and cause my stupid asthma to tone it down to what it was when I was a kid and I could still go hiking and ride my bike as far as I wanted to would be an absolute Godsend.

    • @V.Hansen.
      @V.Hansen. Рік тому

      Have your doctors ever considered a decade transplant?

    • @dualbrainr
      @dualbrainr 3 місяці тому

      @amberkat8147 This is going to sound way out there but aside from all the info about chemicals, bacteria and such there is one thing no one is talking about. It’s the mysterious interactions that happen inside the tiny spaces between the neurons. Called the synapse, this space could be infused with a calming power that can cause dramatic positive changes in how you experience your life. For example, if you could optimize both your head and gut brain together you would find huge improvement in your mental health. Let me know if you’d like to know more.❤

  • @mindyabizniss
    @mindyabizniss 7 років тому +2

    what we ACTUALLY understand about nutrition and everything that's involved with it, bacteria, microbiome etc doesn't even scratch the surface of what's going on... this is exciting, proper understanding of this kind of information changes EVERYTHING

  • @chinookvalley
    @chinookvalley 6 років тому +3

    I went to my neurologist a few years ago and asked if my Vagus Nerve could be affecting my Fibromyalgia, Mitochondrial Myopathy, and Traumatic Brain Injury thru my gut. He got really nervous, called his nurse and they took me into his office and closed the door. They asked how I knew about the Vagus Nerve, they were angry, they said I didn't know what I was talking about, and that I should forget what I was talking about. They took me into another office and wanted me to discuss this with another one of the PA's there. I left and never went back. How many physicians KNOW that the cures are easily found - cutting their practices out of the profits to be made. Do I seem paranoid? Not really, just waking up to what the medical "industry" is doing, and how cures are not welcome. I eat my yoghurt, and have increased my probiotics, see my Naturopathic Doctor, and guess what? I'm getting better!

    • @ZeMarkKrazee
      @ZeMarkKrazee 3 роки тому

      Your story doesn’t make sense at all. You sound like a paranoid conspiracy theorist.

  • @SayAnything8
    @SayAnything8 7 років тому +16

    I can see a new field in psychology being formed during the next few years. It'll be called microbe-psychology.

  • @superjukud
    @superjukud 7 років тому +22

    Have to study for something completely diffrent, yet here i am.

  • @rebecca3647
    @rebecca3647 7 років тому +2

    Putting a literal meaning to the term 'gut feeling'.

  • @invinciblenoodle
    @invinciblenoodle 7 років тому +418

    I have nothing of value to say.

    • @UnderEuropa
      @UnderEuropa 7 років тому +2

      invinciblenoodle don't we all?

    • @mrtannzr
      @mrtannzr 7 років тому +18

      You don't need to because you're a valuable person and I love you.

    • @YourOwnange
      @YourOwnange 7 років тому +5

      Are you really completely invincible?

    • @RialuCaos
      @RialuCaos 7 років тому +26

      If only everyone had your capacity for self-awareness.

    • @stevebluh
      @stevebluh 7 років тому +6

      Best comment I've ever seen. I'll say that instead of letting people I don't know, know what I think.

  • @LaceNWhisky
    @LaceNWhisky 7 років тому +4

    It made me really damn happy when Olivia started the episode so chipper and excited! She's my favorite host SciShow has ever had.

  • @ashi_no_ko
    @ashi_no_ko 7 років тому +12

    I already knew that microbes in my guts have some impact on my brain, but didn`t exactly knew what and how they cause. Thank you for explaining this to me. And especially thanks for the host, whose voice I can listen whole day.

  • @AllenLeland
    @AllenLeland 7 років тому +2

    This is a topic that means a lot to me since when I take a probiotic it really helps my mental state & I have tried to go some time without them & I just don't feel as well.

  • @889bball
    @889bball 5 років тому +2

    These people sound so sure and yet so doubtful at the same time.

  • @rickspalding3047
    @rickspalding3047 7 років тому +4

    If they want to learn more, they should study me. I've always felt blah. I've drank heavier over the years to the point my gut was getting really screwed up, to the point where eating soluble fiber was a major problem while heavy drinking. When this happened, and I ate something with simple sugars, I had the greatest highs and wish I always felt like this. It wasn't a sugar high, I never had a crash and was wondering how I could always feel like this. Hapiper and more confident. Anyways, I would have to go to a clear liquid diet to let my gut heal.

  • @CorpusOrganic
    @CorpusOrganic 7 років тому +3

    does that mean if microbiomes are passed from generation to generation that mental illness in families might not be purely genetic? would be interesting to know. do to my family history.

  • @LeMikerophone
    @LeMikerophone 6 років тому +2

    Of course SciShow would be super beneficial to my dissertation work. Thank you.

  • @LuisDiegoMontero21
    @LuisDiegoMontero21 7 років тому +1

    That is super interesting. in Costa Rica, the Bribri people (an indigenous people) believe that you actually do a lot of your thinking with your gut. They believe the stomach and the liver do the same or more thinking than the brain. They have based their ancient medical treatments (based on herbs and different ways to prepare them) on that belief. It turns out they seem to have, at least, a solid ground for that.

  • @NPEvM
    @NPEvM 7 років тому +6

    Great video topic, very intresting, however I'd like to say that:
    AS a person WITH DYSLEXIA i FIND it pretty HARD TO read some OF YOUR TEXT in the VIDEO. ESPECIALLY HAVING A smaller font LETTERTYPE which IS still TYPED IN caps.
    Easy to read: 7:04
    Realy hard to read: 4:28
    I can imagen that you do this to make it more clear, but for me it actually worsens the readability.

  • @valeriobertoncello1809
    @valeriobertoncello1809 7 років тому +16

    Memes are like the microbiome of the internet. They are little, they reproduce and they spread inside the guts of the net... and I'll tell ya, they surely affect our brains!

    • @johndough23
      @johndough23 4 роки тому +1

      This has been known since the late 90s. memetics Richard Brodie...he also developed the original Microsoft Word...duh en.wikipedia.org/wiki/Richard_Brodie_(programmer)

  • @AnneAndersonFoxiepaws
    @AnneAndersonFoxiepaws 2 роки тому +1

    I have been logging my symptoms with the King's College, London, Zoe app which are front runners in researching the gut microbiome. It's fascinating! I have been logging since it started at the beginning of the pandemic and recently its branched out to other areas of health as it has the largest group of test subjects ever, logging whatever they need. It's a new and amazing way of testing things and of keeping tabs on whatever symptoms each survey needs. It's truly ground breaking and if you can join in the US it's a great way to help scientists and you feel like you've actually contributed.

  • @jayatherton8673
    @jayatherton8673 7 років тому +1

    Thanks for doing an episode on this; I've been wanting one for a while.

  • @robertopran1587
    @robertopran1587 7 років тому +12

    Does anyone know how to get into this type of research? What do you need for that? What kind of studies you need?

    • @kiren3168
      @kiren3168 7 років тому +9

      Robert Opran Biochemistry. Biology.

    • @robertopran1587
      @robertopran1587 7 років тому

      thank you.

    • @pramitbanerjee
      @pramitbanerjee 7 років тому +2

      study a subject called microbiology. Or just biology. Actually, you can study pretty much any of the basic sciences and still get into this research because its all interdisciplinary nowadays

    • @1onearth
      @1onearth 7 років тому +3

      Strains of Bifidobacterium, which is common in the gut flora of many mammals, including humans, have generated the best results so far. Cryan recently published a study in which two varieties of Bifidobacterium produced by his lab were more effective than escitalopram (Lexapro) at treating anxious and depressive behavior in a lab mouse strain known for pathological anxiety. Although Cryan is optimistic that such findings may point the way to the development of psychobiotics, he is wary of hype. “We still need a lot more research into the mechanisms by which gut bacteria interact with the brain,” he says.
      www.scientificamerican.com/article/mental-health-may-depend-on-creatures-in-the-gut/
      A decade ago a research team led by Nobuyuki Sudo, now a professor of internal medicine at Kyushu University in Japan, restrained germ-free mice in a narrow tube for up to an hour and then measured their stress hormone output. The amounts detected in the germ-free animals were far higher than those measured in normal control mice exposed to the same restraint. These hormones are released by the hypothalamic-pituitary-adrenal axis, which in the germ-free mice was clearly dysfunctional. But more important, the scientists also found they could induce more normal hormonal responses simply by pretreating the animals with a single microbe: a bacterium called Bifidobacterium infantis. This finding showed for the first time that intestinal microbes could influence stress responses in the brain and hinted at the possibility of using probiotic treatments to affect brain function in beneficial ways. “It really got the field off the ground,” says Emeran Mayer, a gastroenterologist and director of the Center for Neurobiology of Stress at the University of California, Los Angeles.
      Searching the internet for Emeram Mayer is a good place to start.

  • @Kibaoftheleaves
    @Kibaoftheleaves 7 років тому +4

    Uh maybe those mice were stressed out more because they'd been separated from their mothers at birth. In fact I'm willing to bet they didn't even patch up those c-section mice mommas up after their babies were pulled through their abdomens.

  • @patrickhodson8715
    @patrickhodson8715 7 років тому +1

    There's a thing that can happen where yeast becomes a part of your microbiome, and it causes you to get dangerously drunk when you eat too much sugar and simple carbs like bread. It can be hard to diagnose because it's pretty rare, and because doctors tend not to believe the patients when they come to the hospital drunk and say they haven't been drinking.

  • @coreymerrill3257
    @coreymerrill3257 4 роки тому +2

    This makes for two fecal transplant conversations in a row during lunch today...
    I feel that i can relate to multiple parts of this video from being a cesarean birth, and have major issues be bound or restrained. I also can easily adjust to basically any environmental situation or living situation without it becoming to big of a problem. I in fact have a harder time going to a public place than facing complete power grid failure in the u.s. rational? Nope ? Id help it if I can just figure out how. I can relate by feeling mentally terrible when I eat a poor diet. Depressed and lethargic and dim. I had internal chemical burns in the early two thousands and my digestive track no longer works right. When I have a steady intake of live culture yogurt and/ or Keefer, I have a much easier time of life internally and externally.

  • @KamiltheCamel
    @KamiltheCamel 7 років тому +72

    Too bad my brain didn't send enough signals to certain parts of me because they are now forever stuck being micro.

    • @paperitgel98
      @paperitgel98 7 років тому +7

      KamiltheCamel #justasianthings

    • @KamiltheCamel
      @KamiltheCamel 7 років тому +20

      Not only Asians have small hands.

    • @akshatshah3717
      @akshatshah3717 7 років тому +8

      KamiltheCamel Ya, you were _totally_ talking about your hands... 😉

    • @KamiltheCamel
      @KamiltheCamel 7 років тому +12

      Well at least I like to use my hands on it.

    • @chadwilliams9141
      @chadwilliams9141 7 років тому +1

      KamiltheCamel hey wow

  • @angelikahemker712
    @angelikahemker712 6 років тому +3

    This is a super-interesting and extremely well-done presentation. I have just gone through an entire course on the microbiome on the edX platform which I think is rather boring in comparison. Thank you very much and keep up the fantastic work!

  • @TheKd8lvt
    @TheKd8lvt 6 років тому +2

    Great video!
    I don't know if anyone has tested this, but could the reason the mice were getting more stressed be because their gut wasn't creating as much seratonin, due to the reduced variety of gut microbes? I didn't read the paper, but it seems plausible to me.

  • @AndreaCrisp
    @AndreaCrisp Рік тому +1

    I've been saying for years that medicine of the future will look at a person's genetics and microbiome before anything else. This will help determine the best diet, what prescriptions/vaccines are safe/needed and so much more. NDs and Functional MDs are ahead of the curve. Yet despite knowing that my gut health and genes are the root of my serious health problems I am still dealing with issues. It is hard to recover gut health in the modern world. Sigh.

  • @moremerry57
    @moremerry57 4 роки тому +9

    SciShoe, please do a presentation on the Vagus system. I have just been introduced to it, told it probably figures largely in my mental heatflt struggles.

  • @joshuaolorocisimo7611
    @joshuaolorocisimo7611 7 років тому +5

    I'm currently working on this for my thesis and it's really interesting!!

  • @jamescarson3826
    @jamescarson3826 7 років тому +2

    I'm glad to see some news about this subject, since I was assuming nothing much was being done about it and would be another 20-30 years before the science and medical community as a whole was clued on to the idea that gut health plays a surprising role in both metal health and physical health.
    Right now I have a doctor directed nutrition and diet plan (yes, with probiotics) to help with chronic depression, and I'm making slow but encouraging progress after dealing with it for most of my life. But one thing that seems to keep coming up when trying to get things fixed right has been gut health. Honestly, I've ran into more stuff about the connection between mental disorders and nutrition and gut health than I'd ever care to know.
    Shame though, since I know that the big pharmaceuticals (mostly here in the US) aren't going to like the idea that proper food and microbes might actually be the best medicine, and not the drugs they have spent so much money on researching and looking for a use for.

  • @BubblewrapOracle
    @BubblewrapOracle 6 років тому +2

    I'd like to know how honey affects this, being anti-bacterial and all?

  • @ZennExile
    @ZennExile 7 років тому +242

    Nothing about this is weird.
    We have always known, "You are what you eat"

    • @danielmonteiro2161
      @danielmonteiro2161 7 років тому +3

      those mice must have eaten fecal matter as heavenly possible

    • @catgodswim
      @catgodswim 7 років тому +29

      I dont remember eating a human

    • @MacCoalieCoalson
      @MacCoalieCoalson 7 років тому +1

      Redstone Pro duhhhh your memory was wiped

    • @ozcr6179
      @ozcr6179 7 років тому +1

      Zenn Exile so if I eat pssy then does that turn me into a pssy.

    • @ZennExile
      @ZennExile 7 років тому +8

      Every single day you consume a measurable amount of human, in the form of hair and skin cells.
      So it is not that you don't remember, Redstone Newb, it is that you did not even notice. Because you are a disgusting waste of cognitive ability, and have developed no concept of what it means to have a single perspective, among many.
      You kinda disgust me tbh.

  • @Snailz5
    @Snailz5 7 років тому +3

    That had to be a fun grant proposal to review..."Hey Marty, these guys wanna take poop from people and put it up some mouse butts and see if it makes them act funny. They got some freaky scientists over at (whatever university did this study)!!!"

    • @joshshe3941
      @joshshe3941 7 років тому

      Alexander Cooper they shoved poop 💩 up there butt and then cut the brain up to study it.

    • @Snailz5
      @Snailz5 7 років тому

      ......it's a joke

  • @aaronramsden1657
    @aaronramsden1657 2 роки тому +1

    I know it's anecdotal, but after a long antibiotic course, I was severely depressed, and in the last day I couldn't take it, I threw them in the bin because it was causing me immense stress

  • @LucMMailloux
    @LucMMailloux 7 років тому +1

    Thanks Olivia! This is some crazy stuff I want to hear more about in SciShow Psych

  • @bjrnhjortshjandersen1286
    @bjrnhjortshjandersen1286 3 роки тому +3

    Interesting..but I really would like it if they would pitch down a bit and talk more quietly.

  • @boy638
    @boy638 7 років тому +91

    Uploaded just a minute ago and there's already anus jokes

  • @mabinogidrws
    @mabinogidrws 6 років тому +1

    I'm really anticipating more findings because, as a migraineur, my personal experience is one of both brain and gut suffering.

  • @SC86Canuck
    @SC86Canuck 4 роки тому +1

    Well hopefully we can figure out how to make sure we are getting beneficial things from this microbiome

  • @ridjf
    @ridjf 7 років тому +31

    Can we then make a microbiome promoting baby formula to make super children who learn and handle stress easier?

    • @ooooneeee
      @ooooneeee 7 років тому +17

      ridjf breast milk actually contains many different oligosaccharides which the baby cannot digest to promote helpful bacteria colonization of the gut by feeding them. Baby formula needs to incorporate those to get close to breast milk.

    • @clarelusher
      @clarelusher 7 років тому +14

      Dark Rainbow I'm glad someone pointed that out! I wonder if anyone is studying possible correlations between dramatic decline in breastfeeding rates and dramatic increases in mental health issues in the 'developed' world? Probably not as there is no profit in it! Yet it could be one answer to a conundrum of mental health issues in the developed nations.

    • @cellocovers3982
      @cellocovers3982 7 років тому +29

      it's called breast feeding

    • @jamesburleson1916
      @jamesburleson1916 7 років тому +3

      +Clare Lusher I was thinking something similar. How much does one's diet affect one's mental health or even how one reacts to daily challenges? This entire field of study will likely lead scientists to the conclusion that maintaining a healthy diet is imperative to healthy brain development and maintenance. All these kids who were raised on McDonalds and taught to use these soaps and hand sanitizers that kill 99.99% of bacteria might be so disadvantaged by the negative impact on their microbiome. If you really stop and think about how much you could be effected by poor diet, it kind of puts a lot of things in perspective.

    • @dreadfairy6963
      @dreadfairy6963 5 років тому +2

      There already IS a "formula" for that! It's called BREAST MILK from each of our mothers! XD
      We need to stop trying to create fixes for things, most of our "fixes" lead to more problems. Nature, living by the natural order of our own biology, already has all the fixes! It's because we have moved so far from the natural order of the world that we have so many problems/disorders/illnesses to begin with.

  • @Meandmymirror
    @Meandmymirror 4 роки тому +6

    She is speaking to fast! Neither of my brains can operate with that stress!

  • @tawnyatorgl8731
    @tawnyatorgl8731 7 років тому +1

    great great information! thank you

  • @djinnisequoia
    @djinnisequoia 7 років тому +1

    This is deeply fascinating. It kind of makes me wonder if an individual's microbiome is involved in the cluster of information and conditions we refer to as wisdom.

  • @jitendrasingoriya515
    @jitendrasingoriya515 4 роки тому +5

    She looks like amy from big bang theory 😂

  • @drenidautaj
    @drenidautaj 7 років тому +5

    Always had a gut feeling about this.

  • @urielalbertosanchezm
    @urielalbertosanchezm Рік тому +1

    Fascinating, now I want to know more!

  • @johnbalvin5401
    @johnbalvin5401 3 роки тому +1

    if you think about it, we all started as a whole gut(cell), then just start envolving a brain along it, it wasn't the brain who develop a gut but a gut who develop the brain.
    What if all this time we've been wrong about who are us(we have been always told that it was our brain).
    Also this could explain why some animals can live without brain, so it's not that don't have but we have gotten used to brain as intelligence but now we know the gut is also a brain

  • @papinkelman7695
    @papinkelman7695 7 років тому +6

    there she is...
    and what about midi-chlorians?

  • @MusiCaninesTheMusicalDogs
    @MusiCaninesTheMusicalDogs 7 років тому +5

    I have no brain, though. CheckMate, microbiome! 😁

  • @AngelJabreel
    @AngelJabreel 7 років тому +1

    This is the most interesting i have ever seen by you guys. This might have confirmed a lot of my own thoughts and observations.

  • @MoonLightDDR
    @MoonLightDDR 7 років тому

    Actually Olivia did a lot better than the previous episodes, I think she's trying so hard to meet your expectations, guys!

  • @navieon209
    @navieon209 7 років тому +120

    Thumbs Up for Olivia, I love when she host.

    • @Aleph-Noll
      @Aleph-Noll 7 років тому +7

      other people downvote for the same reason

    • @Snocone333
      @Snocone333 7 років тому +7

      i just like that the channel mixes it up, and she isnt the usual youtube clickbait generator like plenty of channels use their lady members for.

    • @lancemaltby895
      @lancemaltby895 7 років тому +7

      navieon209 I enjoy when she hosts, but her constant hand movements make me feel anxious by the end of most of her videos.

  • @con.k
    @con.k 7 років тому +6

    6:19 serotonin produced in the gut doesn't get to the brain I believe. it acts differently in each organ

    • @pramitbanerjee
      @pramitbanerjee 7 років тому

      that is true. The function of a neurotransmitter seems to vary depending on where they are localized to.

    • @andrewneff5458
      @andrewneff5458 6 років тому

      Sure doesn't, so unless gut and platelet serotonin is what emotion & behavior is all about.... Also, tryptophan does get to the brain (serotonin precursor), but little/no evidence microbes influence ppl's tryptophan levels.

  • @Monjagetitonya
    @Monjagetitonya Рік тому +1

    This work in autism is going to be a game changer! Guaranteed! Moms having C sections and moms getting antibiotics right before giving birth keeps babies from receiving the needed bacteria from the moms vaginal canal… they are actually soaking gauze in moms birth canal who must have c sections and wiping the babies entire body, mouth, nose, eyes and ears. Breastfeeding also provides these needed bacteria for the babies gut! My daughter had antibiotics 3-4 days before giving birth and my grandson is autistic. I am now just learning to make yogurt with the needed bacteria to help build his gut bacteria. Moms should take the bacteria “infantis” the last trimester and even add to formula if nursing isn’t an option. Also! Stop making kids”germ free”… let them play in the dirt… play with animals! Walk barefoot! We’ve ruined our micro biome! Thoughts!

  • @mintysingularity
    @mintysingularity 6 років тому +2

    Also keep in mind, our gut is the brain we had before we had a brain. And plays a huge role in addiction, including cravings for sugar and other chemicals.

  • @seanross7611
    @seanross7611 7 років тому +13

    Can't think of any jokes, might ask my gut

    • @mr_sowong9464
      @mr_sowong9464 7 років тому +1

      Sean Ross pulled out the biggest fart ever

  • @insertnamehere001
    @insertnamehere001 7 років тому +3

    As the old saying goes: 'the way to a man's heart is through his stomach'.

  • @Braddeman
    @Braddeman 7 років тому +1

    Anyone else feel like the host is like Ricky Bobbie in an interview where he doesn’t know what to do with his hands. Don’t usually criticize hosts but this is just funny.

  • @alecbernal3824
    @alecbernal3824 7 років тому +1

    Another thing not mentioned in this video is how most drugs designed to improve mental health (e.g. benzodiazipines, SSRI's, antipsychotics etc.) tend to have profound negative effects on digestion, throwing off gut flora levels. The conclusion this data points to is that psyche meds may exacerbate the source of mood pathologies, while making the symptoms less noticeable making total recovery that much more difficult.

  • @josiahbaumgartner7643
    @josiahbaumgartner7643 7 років тому +4

    I read an article about this from a magazine that just came out this month, coincidence?! Yeah, probably.

    • @josiahbaumgartner7643
      @josiahbaumgartner7643 7 років тому +4

      I'm going to post the entire article here for anyone interested in it.
      "The Enteric Nervous System-Your Body’s “Second Brain”?
      HOW many brains do you have? If you answer “one,” you are correct. Yet, there are other nervous systems in your body. One network of neurons is so extensive that some scientists have referred to it as a “second brain.” It is the enteric nervous system (ENS) and is located, not in your head, but mostly in your belly.
      It takes an enormous amount of coordination and effort for the body to transform food into fuel. Hence, it is fitting that the brain is designed to delegate, as it were, most digestive control to the ENS.
      While much simpler than the brain, the ENS is immensely complex. In humans, it is made up of an estimated 200 to 600 million neurons. This complex network of neurons is built into the digestive system. Scientists believe that if the function of the ENS were to take place in the brain, the needed nerves would be too thick. According to the book The Second Brain, “it is thus both safer and more convenient to let the [digestive system] look after itself.”
      “A CHEMICAL WORKSHOP”
      Food digestion requires a variety of very precise chemical mixtures produced at the right times and delivered to the right locations. Professor Gary Mawe aptly describes the digestive system as “a chemical workshop.” The sophistication of this chemical operation is mind-boggling. For instance, the intestinal wall is lined with specialized cells that act as chemical detectors, or taste receptors, identifying chemicals present in the food you eat. This data helps the ENS enlist the right digestive enzymes to break the food down into particles that the body can absorb. Also, the ENS plays a vital role in monitoring the acidity and other chemical properties of food particles and in adjusting the digestive enzymes accordingly.
      Think of the digestive tract as a factory line managed mostly by the ENS. Your “second brain” moves food through the digestive system by directing the muscles along the wall of the digestive tract to contract. The ENS varies the strength and frequency of these muscle contractions as needed to make the system function like a line of conveyor belts.
      The ENS also supervises safety functions. The food you swallow is likely to contain potentially harmful bacteria. It is no wonder that about 70 to 80 percent of your body’s lymphocyte cells-a vital component of your immune defense system-are housed inside your belly! If you ingest high levels of harmful organisms, the ENS protects the body by triggering powerful contractions that expel most of the toxic matter through vomiting or diarrhea.
      GOOD COMMUNICATION
      While the ENS seems to function independently of the brain, these two nerve centers engage in constant communication. For example, the ENS plays a role in the regulation of hormones that tell the brain when you should eat and how much you should eat. ENS nerve cells signal the brain when you are full and may possibly trigger nausea if you eat too much.
      Even before reading this article, you may have suspected that there is a communication link between your digestive tract and your brain. Have you noticed, for instance, that eating some fatty foods seems to improve your mood? Research suggests that this happens when your ENS sends ‘happy signals’ to your brain, starting a chain reaction that makes you feel better. This may explain why people tend to eat so-called comfort food when feeling stressed. Scientists are exploring the possibility of artificially stimulating the ENS as a treatment for depression.
      Another example of communication between the brain and the digestive system is what has been described as having butterflies in one’s stomach. This feeling may be the result of the ENS diverting blood away from the stomach when the brain experiences tension or stress. Nausea can be another result, as during stress the brain triggers the ENS to change the gut’s normal contractions. According to experts, this brain-gut connection might also be the basis for so-called gut instincts.
      While the ENS may generate such gut feelings, it cannot think for you or direct your decisions. In other words, the ENS is not really a brain. It cannot help you to compose a song, balance your bank account, or do your homework. Still, this marvelous system continues to amaze scientists for its complexity-much of it perhaps still undiscovered. So the next time you are about to eat a meal, pause and think about all the monitoring, data processing, coordination, and communication that is about to take place in your digestive system!"

  • @jameswallace9906
    @jameswallace9906 5 років тому +3

    Your hand motions don’t sync with what your saying

  • @DoorSCARF
    @DoorSCARF 7 років тому

    Wowowowow your speech has improved so much this was a joy to listen to! Well done

  • @amypola5903
    @amypola5903 6 років тому +1

    A new environment might come with new microbes and therefore alleviate stress. I don't know if the mice would know that, but the microbes might.

  • @Hambonillo
    @Hambonillo 7 років тому +6

    I just invented Intesteinstein - It's when you really know your stuff about your stuff.

  • @cup_check_official
    @cup_check_official 7 років тому +112

    Scientists used to think but now they think they are wrong. If i had a nickle for every time i heard that sentence.
    science is great but it always changes which is awesome and weird at the same time. You are sure and unsure of what you know at the same time.
    I just feel like its all Schrodinger's science .-.

    • @cup_check_official
      @cup_check_official 7 років тому +5

      go back to school Bunny

    • @DiegoBQZ
      @DiegoBQZ 7 років тому +23

      It's not that simple. It's an ever-growing evolving sets of rules and axioms that can be used for predictive models. That's the core of science. The fact that something is "wrong" doesn't mean that every aspect of it is incorrect or that some of that information can be used for something bigger. If everything was as Schrodinger-esque as you think it is, why are we not doubting the mere existence of electricity or the fact that we are watching this video?

    • @tuulofdstrxn
      @tuulofdstrxn 7 років тому +7

      Science is about making hypotheses, like "this is the way we think things probably happen", then performing experiments that test those assumptions. At first, results often reinforce the core of the hypothesis, but looking into it more closely with more experimentation, it almost always turns out there's something else going on as well. This way you're sure of what you know, *and* sure of what you *don't know*, which is just as valuable for future research.

    • @yacoale8153
      @yacoale8153 7 років тому +8

      science is always evolving, thats somewhat the definition of science

    • @okie9025
      @okie9025 7 років тому +5

      Tell Me This You say that while you can't construct a simple sentence.

  • @xasia_
    @xasia_ Місяць тому

    Im pretty sure the reason I was such a depressed anxious child ( so anxious id faint all the time due to panic attacks) was because of my poor gut health (maybe triggered by my lack of breast milk )... It really changes your life

  • @juliav.mcclelland2415
    @juliav.mcclelland2415 Рік тому +1

    Do we know which microbes we want a lot of, which ones we want to minimize, and what to eat to achieve that? I.e. the paleo diet says to not eat grains or pseudograins for your gut microbiome - is that right?