BLAST 7 scoring gaps

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  • Опубліковано 27 жов 2018
  • Dr. Rob Edwards from San Diego State University discusses how you score gaps in BLAST, the Basic Local Alignment Search Tool

КОМЕНТАРІ • 7

  • @Edofak
    @Edofak 5 років тому +2

    thank you ...this has been so much help

  • @OnnumMuttaiyum
    @OnnumMuttaiyum 2 роки тому +1

    How the hell did you write all these from that side? That takes insane amount of work

    • @coar
      @coar 2 роки тому

      you could always mirror the video in post ^^! does look super impressive tho

  • @bonnieleela1156
    @bonnieleela1156 3 роки тому +2

    2min19
    I'm not sure you would get a penalty of 12, because there is just a gap opening and no gap extension... If there were 2 consecutive gaps, you would indeed get a penalty of 12.
    But here isn't it just a -10 penalty?

    • @alyxu6508
      @alyxu6508 3 роки тому +3

      I am wondering about that too....

    • @caterinacevallos9822
      @caterinacevallos9822 3 роки тому +1

      He seems to be counting it as the first insertion

    • @JuanOLopezGerena
      @JuanOLopezGerena 3 роки тому +4

      It's -12, because it's a linear expression of the form -(a+bk), where a is the gap opening penalty, b is the gap extension penalty, and k is the number of consecutive gaps. In this particular case, a = 10, b = 2, k = 1. From the user manual: "Thus a gap of k residues receives a total score of -(a+bk); specifically, a gap of length 1 receives the score -(a+b)."