Liver Function 1, Filter between gut and blood

Choose one true statement about the hepatic portal vein, It carries blood from the:
a. liver to the vena cava
b. mesenteric vein to the vena cava
c. liver directly to the gut
d. gut directly to the liver
Choose one true statement about the blood in the hepatic portal vein, Blood in the hepatic portal vein:
a. carries a lower concentrate of bacterial toxins than the hepatic veins
b. carries a higher concentrate of bacterial toxins than the hepatic veins
c. will only carry sugars in the form of glucose
d. carries blood which is approximately 98% saturated with oxygen
Approximately what proportion of liver mass is comprised of hepatocytes
a. 20%
b. 40%
c. 60%
d. 80%
In pharmacology first pass metabolism refers to:
a. The mass of drug metabolised by the liver in any one-hour period
b. The mass of drug metabolised by the liver after intravenous drug administration
c. The proportion of drug metabolised as the drug is carried in the blood from the gut to the hepatic veins
d. The proportion of metabolites synthesised into active drug compounds as the drug is carried in the blood from the gut to the hepatic veins

[@muhammadyaseenmahtaab7820]

My Answers: D B D C.....Thank you Sir.....

[@Campbellteaching]

all correct

[@kaleemullah6436]

Sir you are great

[@antonija2302]

Thank you. Interesting 👀

[@medicallapafsomali2334]

Good teacher

[@liselopez3196]

is the blood carrying to the liver is it deoxygenated ?

[@dr.yuvarajanpalanisamy9805]

thank you sir for simplifying the complex ..1)whether entire gut is drianed by hepato portal shunt sir or only small intestine is connected .my doubt is if we give some medication via anus as suppository whether it has to pass through liver undergoing first pass effect .2) is there any chance to escape first pass effect to minimize dose for oral preparations . 3) i know that sublingual route will escape from first pass effect can we take any medicine via sublingually or any restrictions sir

[@Campbellteaching]

Yes, I think you are right, HPV drains the lower third of the oesophagus right throng to the colon, but Im not sure which part of the colon. For sure the mouth is not drained by HPV, this is why aspirin is faster absorbed if it is chewed, rather than swallowed.

[@dr.yuvarajanpalanisamy9805]

@@Campbellteaching thank you sir.
Rectal route is my long losting doubt whether it is going through liver or not ..I will search sir

[@dr.yuvarajanpalanisamy9805]

@@Campbellteaching thank for your reply sir

[@YASEENKHAN-bf5vd]

Answers.
D B D D

[@Campbellteaching]

First 3 correct well done, but the correct last answer is C. Its essentially the proportion of drug broken down the first time the drug passes thorugh the liver.

[@YASEENKHAN-bf5vd]

Thank u sir

[@kdelka81]

Thank you! Good refresher

[@thebeardednurse187]

Fantastic video.

[@saimashahzad8324]

Always an excellent lecture..I always open your videos when ever I need to understand the topic properly.
May Allah reward you for this.
Thank you sir.

[@adelmohammed7675]

Thanks from kuwait doctor , great .

[@tarmizitaha]

Good Explanation.Thank you

[@vardhiniakula8459]

thankyou very much

[@theresageiger584]

I need help asap