Art Krieg: Introduction to Nucleic Acid Immunity & Implications for Optimizing Cancer Immunotherapy

Introduction to Nucleic Acid Immunity and Its Implications for Optimizing Cancer Immunotherapy
Art Krieg, MD, UMASS Chan Medical School
Starting from the concept and principles of Nucleic Acid Immunity, I will explain why TLR7 and TLR9 are unique among the nucleic acid immune sensing receptors for their ability to activate IFN-a secretion from plasmacytoid dendritic cells, and how their agonists can be used to activate innate immunity to optimize cancer immunotherapy.
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