Systemic lupus erythematosus (SLE) - causes, symptoms, diagnosis & pathology

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  • Опубліковано 29 лис 2024

КОМЕНТАРІ • 1,1 тис.

  • @dashcamera_daily
    @dashcamera_daily 7 років тому +2672

    This channel is a gift to medical students

  • @vineethvishnu9975
    @vineethvishnu9975 6 років тому +617

    My lecturer took 1 hour for this topic.. and you guys nailed it in 11 mins...

    • @georgebadia9518
      @georgebadia9518 6 років тому

      haaaaa

    • @habibmate8466
      @habibmate8466 5 років тому +7

      Mate I’m sure your lecturer gets payed hourly or per lecture he teaches, Id bet money that he’s wasting time on purpose 😂

    • @رواياتمغربية-ر6ق
      @رواياتمغربية-ر6ق 5 років тому +23

      if only you knew how much time it gets to make 1 video

    • @hafizhmanaf1459
      @hafizhmanaf1459 4 роки тому

      And i didn't uderstand that much from my lecturer

    • @intrestingindia5897
      @intrestingindia5897 3 роки тому

      Is there any treatment.....plz help

  • @leslieware2125
    @leslieware2125 2 роки тому +117

    I am a registered nurse with 13 years of experience and diagnosed with SLE approximately 5 years ago. This is the first time that I completely understand the disease process and why each of these tests are ordered during times of disease activity. Thank you!

  • @AdrianaMartinez-mv8js
    @AdrianaMartinez-mv8js 5 років тому +38

    I was diagnosed in ‘98 and I’m 2009 I got a kidney transplant but it only lasted 4 years. I am now doing peritoneal dialysis and going through the Transplant Work Up again to try and get on The List once again and hopefully I will get that amazing gift. I have a gorgeous daughter and 3 amazing and gorgeous grandchildren 💖. This video was spot on. I pray for all of us and everyone that is going through some kind of illness. Stay Strong 💪🏼💜💜💜

    • @ايهأمير-ك8غ
      @ايهأمير-ك8غ 9 місяців тому

      الشفاء العاجل أن شاء الله

    • @9doyouknow09
      @9doyouknow09 4 місяці тому

      What symptoms do you have?

    • @JJONNYREPP
      @JJONNYREPP 3 місяці тому

      Fkannery o'connor allegedly suffered it.....

    • @JoshuaTraffanstedt
      @JoshuaTraffanstedt 2 місяці тому +1

      Dang. I'm sorry to hear. I just found out today I have lupus. I hope you're able to get back on the list and get a transplant. Scary stuff.

    • @JJONNYREPP
      @JJONNYREPP 2 місяці тому

      @@JoshuaTraffanstedt Comments on ‘Systemic lupus erythematosus (SLE) - causes, symptoms, diagnosis & pathology’ 0358am 25.8.24 ahhhh...i think you'll have caught it off my neighbours and local farm hands... they enjoy inducing stuff in folks or having them catch stuff... they like to meddle and shit... lupus is essentially TB of the skin... having lards enter one's home and rub themselves on your clothes and linen doesn't help, either... urrrghhh... scary stuff. probably quite telling that diseases might be more tolerable than the folks featured in one's locale... flannery o'connor suffered that i am informed. wonder if it isn't mistaken for over indulgence with the bottle, though...?

  • @queenfae2182
    @queenfae2182 2 роки тому +48

    I'm being investigated for lupus and this video helps me understand the disease a lot better. Thank you 🙂

    • @osmosis
      @osmosis  2 роки тому +5

      Hope our video helped! 🙏🏼

    • @lisamarie5536
      @lisamarie5536 2 роки тому

      Same here!

    • @nancycarlos5695
      @nancycarlos5695 2 роки тому

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on UA-cam i come and cross Dr.Auchi on UA-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...

    • @sm.663
      @sm.663 2 роки тому

      What symptoms u are having?

    • @nancycarlos5695
      @nancycarlos5695 2 роки тому +1

      @@sm.663 I was having hair lost as my lupus symptoms..

  • @VuelaBand
    @VuelaBand 7 років тому +10

    I go to Harvard Medical School and my professor posted one of your videos as a resource. Now I've been using Osmosis for months and can honestly say it's one of the best resources on youtube. Thanks so much for the amazing videos! Please keep em coming

  • @dr.debbiewilliams
    @dr.debbiewilliams 7 місяців тому +4

    I was diagnosed with SLE, but my Antinuclear Antibodies corrected themselves. I recently showed my Mother's Nurse, and she was surprised as were my doctors. So was I. I've been testing negative consistently for years after being hospitalized and receiving chemotherapy. I also has a TIA. So far, things are going well by using food as medicine as opposed to drug therapy. I have two Doctorates in Naturopathic Medicine, One in Chinese Medicine and am a few credits away from fully qualifying for my MD. I'm also studying Law, and other topics. I don't know how you feel about God, but though it gets hard to manage juggling life's elements, I believe God is healing me for a greater purpose.

  • @mehressagreen4615
    @mehressagreen4615 7 років тому +252

    Thank you so much for this video, I was diagnosed with severe SLE and Antiphospholipid antibody syndrome around 7 months ago, and although I know the medications and treatments, I want to understand the aetiology and how to interpret my blood results. This is empowering and invaluable. From reading the comments there are so many other sufferers and desperate medical students who feel the same. You've now given me a springboard of terminology research into further

  • @michaelmccray7782
    @michaelmccray7782 7 років тому +859

    "Avoid sunlight". Maybe the word "Lupus" is a historical reference to having to stay out of the sun...?
    (Werewolves only come out at night)

    • @ramsuresh1942
      @ramsuresh1942 6 років тому +3

      Michael McCray ha ha..great

    • @davidhoward2487
      @davidhoward2487 6 років тому +94

      No, it's called Lupus because it's like a wolf (Lupus) in sheep's clothing...mimics so many symptoms of other diseases...

    • @micaelpompermayer9548
      @micaelpompermayer9548 6 років тому +4

      So, shouldn't it be named "wolf-rash"? Just saying.@Chaston Ellis

    • @mohammadsultan8894
      @mohammadsultan8894 5 років тому

      Michael McCray wow

    • @jerrymartin5922
      @jerrymartin5922 5 років тому +19

      I agree with all these answers. I have lived with lupus for many years but diagnosed in 2016. Stay strong!
      May is also Lupus awareness month!

  • @jamilahadade4412
    @jamilahadade4412 3 роки тому +124

    Thanks for this great explanation of Lupus. I’ve been recently diagnosed with Lupus but the doctor didn’t give me any information on this disease. Now I understand what type of this disease this is. Lupus sounds like a complicated disease. It’s quite scary. Everything’s in God’s hands. Hopefully they’ll be a cure soon since so many people suffer from this destructive disease.

    • @ellaelliott4415
      @ellaelliott4415 2 роки тому +3

      It's complicated and scary but can be manageable. I'm sorry you didn't get information from your doctor. Being in the dark is the worst. I've had it for a few years now, but the good thing is, new treatments are in the works.

    • @mistysimms2708
      @mistysimms2708 2 роки тому +1

      My mom was just diagnosed as well. Doctor gave her any information either 😢

    • @rudransh8829
      @rudransh8829 Рік тому

      ​@@mistysimms2708at what age your mom diagnosed?

    • @JoshuaTraffanstedt
      @JoshuaTraffanstedt 2 місяці тому

      ​@@rudransh8829I'm 37 and was just diagnosed today. But I've had facial rashes for about 10 years now at least. Doctors would always tell Me it was an allergic reaction or something like that. Best thing folks can do is make an appointment with a dermatologist. They did a skin biopsy and told me a week later (today) it was lupus.

  • @fabmedici1703
    @fabmedici1703 2 роки тому +4

    I have been a doctor for over 5 years now but I don’t think I ever understood SLE before! Thank you!

    • @osmosis
      @osmosis  2 роки тому

      Glad to help ❤️

  • @vegliberationx
    @vegliberationx 8 років тому +225

    Wowwwww absolutley amazing, you need only 11 minutes in explain this pathology. I understood very well, much better than book. Thank you for this!

    • @osmosis
      @osmosis  8 років тому +24

      Perfect! You're welcome AJ.

    • @AiSHAisasingleladyAb
      @AiSHAisasingleladyAb 7 років тому +2

      Osmosis
      please can you Translate to Arabic، I really need this to understand medical words well! Thanks. 😊☺

    • @ralphkeeldar4726
      @ralphkeeldar4726 4 роки тому

      Nice of you to say that. On my place on this website i will tell people what they can do if the treatment of the doctors don't help. Good luck !

    • @intrestingindia5897
      @intrestingindia5897 3 роки тому

      Is their any treatment.....plz help

  • @PasanBhathiya
    @PasanBhathiya 7 років тому +22

    I really like the casual tone of these videos, saying "alright!" and "okay!" often. 😊

  • @bloodreno
    @bloodreno Рік тому +3

    Came here after my dad had a fall. He’s getting older and he has lupus which has brought along arthritis. I’ve always known he had it but today I couldn’t sleep thinking about him and found this video. Thank you for the knowledge. I always avoided my dads disease but only out of ignorance

    • @osmosis
      @osmosis  Рік тому

      We hope this video was able to help, Julian 🙏🏼

  • @豆豆-z3i
    @豆豆-z3i 11 місяців тому +1

    Man ur a savior.literally saved my pathology singlehandedly

  • @lencovic9571
    @lencovic9571 8 років тому +47

    I can't believe how brilliant these videos are - you are doing everyone a big favor, I'm certain you'll get more traction

    • @osmosis
      @osmosis  8 років тому +5

      +Lencovic Thanks so much!!

    • @rahmatansari6623
      @rahmatansari6623 2 роки тому

      Meeting Dr Ewi1 on UA-cam has really been one of the best day of my life after years of suffering I have been finally cured from lupus thanks doc God bless you,

  • @jordani024
    @jordani024 6 років тому +38

    Shoutout to Osmosis for getting me through 4 years of Nursing School

  • @annesofiebille747
    @annesofiebille747 8 років тому +75

    Thank you for explaining this complicated stuff so well! I suffer from SLE and have struggled to understand for ages.Now both me and my husband are more clarified.

    • @uglyindian69420
      @uglyindian69420 4 роки тому +1

      Hi.
      How are you now ?
      My mother had it before having me. I'm 24 now. She's facing some comlexities now.

    • @intrestingindia5897
      @intrestingindia5897 3 роки тому

      Is there any treatment plz help

    • @ايةحلميمحمد-ج7ب
      @ايةحلميمحمد-ج7ب 3 роки тому

      @@intrestingindia5897 yes I suffer from it too
      There are immune modulating drugs to improve it , but SLE chronic and u should continue to these drugs

    • @kobeni1524
      @kobeni1524 2 роки тому

      @@intrestingindia5897 I honestly don't think so, but you can make your life easier with medicine and taking care of food / less salt / taking care of yourself :)

  • @shaaperas
    @shaaperas 8 років тому +91

    The best SLE video I have seen. Thank you.

    • @osmosis
      @osmosis  8 років тому +9

      Thanks!

    • @intrestingindia5897
      @intrestingindia5897 3 роки тому

      Is there any treatment plz help

    • @shaaperas
      @shaaperas 3 роки тому

      @@intrestingindia5897 Generally, the treatment plan depends on the severity of the disease ranging from the use of Hydroxychloroquine, NSAIDS, to corticosteroids and immunosuppressants. As with many autoimmune disorders, a specialist is essential for proper treatment. I hope it helps.

  • @skylark5789
    @skylark5789 6 років тому +5

    My God, this guy's a genius. Thank God for people who did their homework in school, took their studies seriously, had supportive parents and family and the means to go to medical school. He rattled off his medical jargon and terminology like a total pro. Great explanation of a very, very complex disease.

  • @kevinfeliciano5959
    @kevinfeliciano5959 5 років тому +7

    Still watching this in 2019. Even though the criteria has changed, the very essence of the disease mechanism is very much briefly explained without missing any important info. Thank you as always, Osmosis!

  • @sarahmina1442
    @sarahmina1442 4 роки тому +116

    "It's HIP to get lupus" mnemonic for drug inducing lupus: Hydrazaline, Isoniazide, Procainamide.

    • @laurakeyse9944
      @laurakeyse9944 3 роки тому

      I'm allergic to sulphur drugs..and Sulphates ... Which means no wine for me..although there are some non sulphate wines out there..expensive..sulphate are used as preservatives in a whole lot of stuff.

    • @johnsonlee4130
      @johnsonlee4130 3 роки тому

      I want you to know that there is a cure for lupus and I cured mine with herbal remedy form Dr Ehime who I met on UA-cam channel. His name is Dr Ehime.

    • @Drhoor111
      @Drhoor111 3 роки тому

      Hydralazine*,Isoniazid*

    • @pierce1234567891
      @pierce1234567891 4 місяці тому +1

      @@Drhoor111 we knew what he meant JO

  • @ggwyn6206
    @ggwyn6206 3 роки тому +14

    I was diagnosed with this recently - with 7 of the criteria met. I’m a freshman in college but I want to be a (cardio thoracic ) surgeon eventually so I found this incredibly interesting, thank you very much.

  • @drblaneyphysics
    @drblaneyphysics 2 роки тому +3

    low dose naltrexone also being used to lower inflammatory reactions in lupus. thank you for this fine video. much appreciated.

  • @Dr.Nantiwa
    @Dr.Nantiwa 8 місяців тому +1

    Wow yesterday a patient came in with the exact set of symptoms. It all makes sense thanks! It was really helpfull

    • @osmosis
      @osmosis  8 місяців тому +1

      We're glad to know that this video was able to help! 🙏🏼

  • @Gnokhi
    @Gnokhi 7 років тому +13

    Nice guys..One suggestion.... Kindly update this SLE video.... The DIAGNOSTIC CRITERIA HAVE BEEN CHANGED since 2012. Thanks in advance.... Keep posting more...

  • @kimurakala7450
    @kimurakala7450 8 років тому +9

    This is the best youtube medical lecture channel I have ever seen. Thank you so much.

    • @osmosis
      @osmosis  8 років тому +1

      Thank you!!

  • @Claudia112005
    @Claudia112005 Рік тому +2

    I accidentally typed SLE instead of sleep. I was looking for sleep videos. This put me to sleep quicker than any sleep meditations I used before. I now listen to this to fall asleep. Goodnight.

  • @kitt1226
    @kitt1226 3 роки тому +18

    My mother was diagnosed with SLE and she’s having a flair up… she has it pretty severe and it’s really hard to watch. I’ve had to call my dad to rush her to the hospital bc of serious high fever and bp. She was delirious and in and out of consciousness. I’ll have to leave the country soon to go to the military and try to support my family. My mom is 48 and my dad 49, I’m 17 (18 in a month) and we can barely pay rent… I’m so worried for them but this is the only way they’ll be able to live at least semi comfortably in the last 30 or so years of their lives. I just hope I can get her help and although I care we have a rough relationship and her marriage is not going well either. This just have to get better ❤️‍🩹

    • @osmosis
      @osmosis  3 роки тому +3

      We're rooting for you, Kitt! We admire your resilience! 💖

    • @kitt1226
      @kitt1226 3 роки тому +6

      @@osmosisthank you so much, she’s doing better now and finally out of bed. I can just hope for the best now🙂

    • @nancycarlos5695
      @nancycarlos5695 2 роки тому

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on UA-cam i come and cross Dr.Auchi on UA-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...

    • @labyrinthdrew9543
      @labyrinthdrew9543 2 роки тому +1

      @@kitt1226 how long did it take for her to get out of bed? Pls tell... I'm 17 and my mother is going through the same, she is in bed... Bad condition.. Idk what to do

    • @ايهأمير-ك8غ
      @ايهأمير-ك8غ 9 місяців тому +1

      كان الله في عونك اخي والشفاء العاجل للوالده

  • @orianawr9579
    @orianawr9579 3 роки тому +2

    I am a high school biology student and this video helps me a lot to do my project about Lupus

    • @osmosis
      @osmosis  3 роки тому +2

      Glad to be of help, Oriana! 😊

  • @sakurarosabellmathews
    @sakurarosabellmathews 3 роки тому +6

    Hi, guys, our accident happened on 5/21/21, Mom and me. I got into a car crash at 1:15. Thankfully, we are alive. We have no broken bones, just bruises, thankfully. The car crash was not my mom's fault. It was a dude. The dude did a turn right in front of us. It happened on 108 Street right in front of Northgate. So please send prayers and me and my mom, and the other driver. So please pray for us.

    • @adamuwalkilausman8280
      @adamuwalkilausman8280 3 роки тому

      Blessings,Got a permanent cure for lupus
      after using dr udoka herbal remedy since February 5th 2021

    • @nancycarlos5695
      @nancycarlos5695 2 роки тому

      I have been suffering from Lupus disease for some year without having a solution to it until i done a research on UA-cam i come and cross Dr.Auchi on UA-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...

  • @sashahayusuke
    @sashahayusuke 3 роки тому +1

    No even a medical student, didn’t even take basic biology in highschool (which I regret, economics was boring) but I’m here to understand the SLE that has plagued my life. Thank you for the video, it was very easy to understand !

    • @osmosis
      @osmosis  3 роки тому

      Thanks for the feedback, Sasha! 😊

  • @FirasRabi
    @FirasRabi 7 років тому +22

    Very well done video. Went through the complex pathophysiology in an easy-to-follow step-by-step process that greatly simplified it, and did it without the boring non-informative and non-beneficial information that plagues other teaching videos. Thank you and keep up the good work.

  • @seungsteele632
    @seungsteele632 3 роки тому +1

    I just spent hours reading this, yet didn't understand it on this level....thank you!

    • @osmosis
      @osmosis  3 роки тому

      Glad it helped, Seung Mi! ❤️

    • @osmosis
      @osmosis  2 роки тому

      Hi Seung! 👏🏼
      Thank you for providing us with the great feedback on this video. We'd love to highlight your quote and share it with our community of learners through our marketing channels. Can you respond and let us know if you approve this request? We look forward to hearing back from you and hopefully hearing more feedback from you in the future. 😊
      Warmly,
      Osmosis Customer Experience Team

  • @coewayboulder
    @coewayboulder 7 років тому +9

    So fantastically done - concise but yet mentioning every important detail - great job!

    • @osmosis
      @osmosis  7 років тому +1

      Thank you, Coeway! We're glad you're finding our videos useful. If you haven't yet checked out our educational platform we have a bunch of tools that we think you'd like. These include unreleased videos, tens of thousands of flashcards and multiple-choice practice questions, study workspaces, and daily exam schedule organizers to help you learn medicine. You can sign up for a free trial of Osmosis Prime here: bit.ly/2ut5ZEJ

    • @rahmatansari6623
      @rahmatansari6623 2 роки тому

      Meeting Dr Ewi1 on UA-cam has really been one of the best day of my life after years of suffering I have been finally cured from lupus thanks doc God bless you,

  • @Farhan344
    @Farhan344 4 роки тому +1

    A very good thing about this channel is... The recape of whole lecture in few secs

  • @binjai3747
    @binjai3747 2 роки тому +19

    With this video my headache while learning is gone thanks !

    • @osmosis
      @osmosis  2 роки тому +4

      You're welcome! 🤓

  • @blahblah-ug5dw
    @blahblah-ug5dw 3 роки тому +2

    This channel is a gift to us medical students for real, until they ask us to visit their channel for topics !

  • @Ed-lw8bw
    @Ed-lw8bw 6 років тому +12

    Can’t trust anyone, not even your own cells

  • @Joh-AnnMarah
    @Joh-AnnMarah Рік тому

    I love when he said we totally got this. I made me let out a sigh of relief thanks osmosis!! the first semester of advanced patho, and these vids are helping tremendously!!

    • @osmosis
      @osmosis  Рік тому

      Always our pleasure to help! 🥰

  • @nene7626
    @nene7626 4 роки тому +1

    I was just diagnosed. Thank you for this video.

  • @thelifeofmadisona8211
    @thelifeofmadisona8211 3 роки тому +1

    Thankful for the support system that surrounds lupus!

  • @rosestone5091
    @rosestone5091 7 років тому +4

    Best comprehensive yet understandable explanation of lupus I have seen! Thanks.

  • @doctorsweety1976
    @doctorsweety1976 Рік тому

    I've exam on my head and I was so anxious about that.. But reading comments down here I took a deep breath after coming to know so many people are suffering from this destructive disease and I'm worry to just memorize it. We're not same folks 😢

  • @divyasingh1295
    @divyasingh1295 4 роки тому +4

    I got to know from Quora about this channel and it seems as if I have discovered a treasure.Kudos to the team who are so efficient in explaining the topics in such a short span.Very helpful❤

    • @temihannah874
      @temihannah874 3 роки тому

      I truly appreciate the admin for uploading this primitive video.. Very useful information was given out.. thanks for the video.
      **This is my healing testimony comment about how I was healed from Genital Herpes. I am recommending "Molemen Herbs" on UA-cam or Facebook. They have the best holistic natural remedies for better treatment and everlasting cure to all diseases and viruses. You can reach them on phone/ WhatsApp at +13237766767..

  • @OnlyJalenPhd
    @OnlyJalenPhd 2 роки тому +2

    Unfortunately, my ANA was negative, and it’s taken years for an answer. I have NPSLE and it took my rheumatologist 1.5 years to put it together. The symptoms I have: RA, Aps, osteoporosis, I’ve had 2 TIA’s, and now shaking in hands, memory loss, uncontrollable movements, peripheral neuropath, and Hashimoto’s…my kidneys and liver are in need of a lot of help. My last labs show my RBC’s too low. Bun too low, Bun/creatinine, too low. Lesions in nose, mouth, skin…W/ all the symptoms, he put it together. Thankfully he found it! Now a treatment plan can begin!

    • @jameslight8746
      @jameslight8746 2 роки тому

      Having Shingles Virus is not the end of life , I got cured after using Doctor Ani John herbal supplement within 14days..

    • @OnlyJalenPhd
      @OnlyJalenPhd 2 роки тому

      @@jameslight8746 huh? I didn’t say anything about shingles.

    • @DeepakRajput2000
      @DeepakRajput2000 Рік тому +1

      @@OnlyJalenPhd then Do you have lupus?

    • @OnlyJalenPhd
      @OnlyJalenPhd Рік тому

      @@DeepakRajput2000 they have tested me for lupus ever since I was in my early 20’s. My husband and I suffered 5 miscarriages, so they thought lupus then. I have every symptom of lupus, but the test is always new.

    • @DeepakRajput2000
      @DeepakRajput2000 Рік тому +1

      @@OnlyJalenPhd Does lupus test came back negative?

  • @alondramarrero924
    @alondramarrero924 7 років тому +3

    thank you so much as a science student I can finally understand my illness at a molecular level

  • @catheryneclark5055
    @catheryneclark5055 6 років тому +1

    Osmosis can explain a disease more quickly and better than anything. Such an aid in research papers and in nursing school studies! Thanks osmosis!

  • @quality169
    @quality169 3 роки тому +17

    I wish I knew people with lupus. I was diagnosed 2 months ago, I’m currently 16 and I feel so alone, I don’t know why there aren’t any teen support groups anywhere, I’ve been searching for awhile

    • @sakurarosabellmathews
      @sakurarosabellmathews 3 роки тому +1

      Well, now you do. I have sle lupus.

    • @mihaelatepsic3264
      @mihaelatepsic3264 3 роки тому

      What are first symptoms?

    • @nahomycallejas3632
      @nahomycallejas3632 3 роки тому +1

      I feel you, I was diagnosed when I was 13 years old. I'm 19 and I still haven't met any teenager with lupus

    • @quality169
      @quality169 3 роки тому +3

      @@mihaelatepsic3264 For me I thought I had carpal tunnel syndrome for the longest time, I’d have really bad pains in my joints and I couldn’t even sleep at night. My hands and feet would get swollen and I was really sick. You’ll know when or if somethings wrong, I had to spend a week in the hospital when I was first diagnosed because my lungs were collapsing and I had a few other issues. Hope you’re doing well.

    • @mihaelatepsic3264
      @mihaelatepsic3264 3 роки тому

      @@quality169 any rash?

  • @3kbschannel288
    @3kbschannel288 7 років тому +1

    You (guy or guys) are so great. Thank you so much. The speaker is great too -but I'd recommend him to slow down at the important points and leave his fast speech for the already (ought-to-be) known facts.-
    He's great.
    Thanks so much ❤️

  • @kanelikes19
    @kanelikes19 8 років тому +293

    " Alright. Systemic Lupus Erythematosus... 'Kay, we totally got this.." Lol

    • @juliocsepulveda
      @juliocsepulveda 8 років тому +12

      Hehehe...Immunology is extremely difficult and complex.

    • @ramsuresh1942
      @ramsuresh1942 6 років тому +1

      ha haa

    • @ramsuresh1942
      @ramsuresh1942 6 років тому +2

      Julio Sepulveda and poorly understood

    • @TheNexusChronus
      @TheNexusChronus 6 років тому +8

      kassiani. When your immune system hates your guts...and your heart, kidneys, brain, jionts, skin, pleura and itself :D

    • @julioperez5380
      @julioperez5380 4 роки тому +1

      Omg my name is julio too

  • @drkashishtarwani8493
    @drkashishtarwani8493 7 років тому

    One can only explain simply when one has understood clearly...same goes for u Osmosis...thanks for the beautiful channel!

  • @jannmikoingelrabagogamingc6012
    @jannmikoingelrabagogamingc6012 2 роки тому +5

    Ah, at last - Dr. House's most famous diagnosis, for every single one of his patients, really.

    • @jameslight8746
      @jameslight8746 2 роки тому

      Having Shingles Virus is not the end of life , I got cured after using Doctor Ani John herbal supplement within 14days..

  • @anyaforger654
    @anyaforger654 Рік тому +1

    I was suffering from severe joint pain in my fingers small joints, although i don't usually get any rash but my hand hurts a lot more when I am exposed to sun for long or in very cold temperature/in Air conditioned place for too long, I recently got tested positive for Antinuclear Antibodies with high intensity (++++) ..my rheumatologist ruled out it as SLE even though i don't have all the symptoms of it!

  • @annt2070
    @annt2070 7 років тому +91

    This channel is AMAZING. 100000 karma points to you for helping a desperate medical student in the middle of the night! :D

  • @sruthyviji8040
    @sruthyviji8040 Рік тому +1

    Thanks a lot . Now I'm able to understand the concept. Ur channel is the best for all the concepts .

    • @osmosis
      @osmosis  Рік тому

      Glad to hear that, Sruthy! ❤️

  • @Yuefei-xh1tl
    @Yuefei-xh1tl Рік тому

    Hello, I am a 16-year-old patient of SLE. Now I am in a stable period after treatment, but I realize that many people around me do not know about this disease. I hope I can do some publicity and science popularization work. I think the explanation in the [specific scenarios ] paragraph is very simple and easy to understand! BTW I will mark your account and link when making popular science videos in China. Thank you.

    • @osmosis
      @osmosis  Рік тому

      We wish you all the best and we're glad that you appreciate our video 🥰❤️🙏🏼

  • @cuorenerazzurro1661
    @cuorenerazzurro1661 4 роки тому +3

    For 2 years my doctors, many rheumatologist and immunologists thought I was fool and tried to convince me I didn t have it. The disease progressed and I needed to go to a clinic in Russia with physicians for them to do deeper analysis and put a diagnosis just more than a month ago. This disease is the worst possible thing with some of other AD and cancers, after my stem cell treatment hope will be better and I have nothing to lose. The worst thing is that after plenty researches I understood that I m the only responsible because the lifestyle I had during the 2016-2017 academic year... So frustrating

    • @pc-vv8uv
      @pc-vv8uv Рік тому

      How did your treatment go

  • @KatalinaLaughs
    @KatalinaLaughs 6 років тому

    This channel is a life saver , my pathology teacher she gives us packets and powerpoints but I learn and understand the material better in a video and someone explaining it in full detail with photos. Thank you 😊

  • @parveenapsana6517
    @parveenapsana6517 2 роки тому +2

    I was diagnosed with lupus 5 months ago.. For me there were many symptoms.. I went through so many struggles it affected my kidneys. Currently I am taking medications and the disease is in control.. Anyone have gone through lupus blood clots in legs?? If yes please reply me in this..

    • @trevorhawkins5559
      @trevorhawkins5559 2 роки тому

      I will advised you to contact Dr. Odion herbal remedies on you for your permanent cure

    • @jameslight8746
      @jameslight8746 2 роки тому

      Having Shingles Virus is not the end of life , I got cured after using Doctor Ani John herbal supplement within 14days..

  • @tanvi2011luv
    @tanvi2011luv 8 років тому +2

    You guys are soooo good! I'm an img studying for USMLE and this is like a god gift!
    Texting all of my friends about you guys asap! 💖

  • @paulineneal5851
    @paulineneal5851 2 роки тому +2

    Really like your videos.... you explain things so well.would love to see you make a video about nf1 and chiari. Thank you.

    • @jameslight8746
      @jameslight8746 2 роки тому

      Having Shingles Virus is not the end of life , I got cured after using Doctor Ani John herbal supplement within 14days..

  • @LordShrub
    @LordShrub Рік тому +1

    Thanks for the explanation! I just went to the doctor about a persistent malar rash so I am going to get tested against these antibodies as well as anti-Ro and anti-La antibodies for suspicion of SLE.

  • @ElectricAMV
    @ElectricAMV 8 років тому +12

    Absolutely amazing video, this channel will blow up soon!

  • @razsabah5587
    @razsabah5587 2 роки тому +1

    Thank you so much for explaining SLE 10x better in 11 minutes than my board certified lecturer did.

    • @osmosis
      @osmosis  2 роки тому

      You're very welcome, Raz! We appreciate the kind feedback ❤️

    • @jameslight8746
      @jameslight8746 2 роки тому

      Having Shingles Virus is not the end of life , I got cured after using Doctor Ani John herbal supplement within 14days..

  • @Wildewhitley
    @Wildewhitley 2 роки тому +5

    I have had APS/ autoimmune illness all my life and have finally learned it comes from food!!!! I went 100% organic and have had more progress in 5 months than I've had with any treatment over my 34 years of seeking help. I had to give up all the goodies, you might only need to give up 1, or 3 like red meat, gluten, dairy, nightshade vegetables, caffeine, sugar, and anything highly processed. It's amazing! Actually feeling healthy!!!! Goodbye life long illness!!!!!!

    • @9doyouknow09
      @9doyouknow09 4 місяці тому

      What symptoms do you have?

    • @Wildewhitley
      @Wildewhitley 4 місяці тому

      @9doyouknow09 I had severe psoriasis since 4, I had my first blood clotting episode when I was 10, & many more since then. I had heartburn at 12, and incontinence by 16 was chronically bloated and constipated. Reached the breaking point when I found out I had severe bone loss at age 33.
      Now littery, none of that except the bone loss & the psoriasis has a couple patches that are still fading. The rest of the symptoms are gone entirely!
      Food is amazing!

    • @9doyouknow09
      @9doyouknow09 4 місяці тому

      @@Wildewhitley thank you..I am going to follow that .

  • @jeank5821
    @jeank5821 6 років тому

    Hi! I'am colombian doctor and you videos are very specials, of great helps for patients! Congratulations!!! Kepp going

  • @demothi1
    @demothi1 3 роки тому +4

    Been suffering from SLE and then I have Anisocytosis, anemia, chronic urticaria, and other blood related illnesses. Are they related?

  • @faktasheetali4111
    @faktasheetali4111 7 років тому +1

    Thanks a lot i got university exam tomorrow n it helped me a lot

  • @razahaider5088
    @razahaider5088 3 роки тому +3

    Very informative thank you very much for explanation in detail

    • @osmosis
      @osmosis  3 роки тому

      Glad you appreciate it, Raza! 🙏

  • @Juliana-yh4mj
    @Juliana-yh4mj 7 років тому +1

    Thank you!!! I'm a medical student and the videos are incredible !

  • @mlilylotha8696
    @mlilylotha8696 3 роки тому +4

    Please tell me,sle specialist doctors lam sle patient

  • @EiliyaLavasani
    @EiliyaLavasani 7 місяців тому

    Your channel is amazing, I'm actually watching every related video to a specific disease before diving into my books! Thank you very much for your great channel 😎❤

    • @osmosis
      @osmosis  6 місяців тому +1

      Most welcome 💕

  • @mrinaliniagrawal2554
    @mrinaliniagrawal2554 8 років тому +3

    Please do an update in the criteria of diagnosis - SLICC

  • @berliantisalamahu730
    @berliantisalamahu730 6 років тому

    I have my block exam the day after tmrrow and I think this will save me a lot of time. Thank you so much!

  • @zas881
    @zas881 4 роки тому +2

    Thank you so much from 2020. What a development though!

  • @cyranodebergerac5817
    @cyranodebergerac5817 6 років тому

    I comprehended deeply this topic by watching you instead of reading Basic Pathology of Robbins, thank you very much

  • @snowinseptember7939
    @snowinseptember7939 5 років тому +46

    apoptosis does not lead to an inflammatory reaction! in apoptosis the cell is divided into many vesicles with an eat-me signal on the outside of their membrane. the vesicles then get digested by macrophages. this way nothing from the inside of the cell (proteins, dna, etc) gets outside the cells which would trigger an inflammatory reaction.
    what's described in the video is necrosis, which is unprogrammed cell death and in which the cell bursts and cell contents are released and trigger an inflammatory reaction.

    • @merleh9455
      @merleh9455 5 років тому +2

      snowinseptember 7 thats right!

    • @Ronald_Jon
      @Ronald_Jon 5 років тому

      There seem to be important distinctions between the two processes, Necrosis and Apoptosis, that would warrant a possible edit to the video. Are there no methods to induce apoptosis in these damage cells so that inflammation isn't triggered?.

    • @andreab1805
      @andreab1805 4 роки тому +5

      You can have inflammation from apoptosis if the clearance is slow

    • @KristinaTheCoolGirl
      @KristinaTheCoolGirl 4 роки тому +6

      I think they just forgot to mention that in SLE, you have impaired apoptosis process so apoptosis resembles necrosis.

    • @mariakanilab9847
      @mariakanilab9847 2 роки тому

      necrosis is not programmed cell death,

  • @shantanurout
    @shantanurout 2 роки тому

    Today was my pathology exam and I just watched this video the previous night as I could not understand the text. It was so helpful. I got question on SLE in the exam. Thank you so much for such crisp summary of one of the major diseases in medicine.

    • @osmosis
      @osmosis  2 роки тому +1

      Hi Shantanu! Thanks for sharing! We're glad that our video was able to help in your exam! ❤️

  • @buildawall5803
    @buildawall5803 2 роки тому +3

    Rip in peace 🕊️ mom 1963-2022 this damn thing killed her

    • @osmosis
      @osmosis  2 роки тому +1

      We're sorry about your mom. Our thoughts are with you today. 🙏🏼

    • @labyrinthdrew9543
      @labyrinthdrew9543 Рік тому

      This thing killed my mother as well 1971-2022

  • @gunhildrandom
    @gunhildrandom 4 роки тому +1

    Best explanation of lupus I’ve encountered so far. Thanks for it!

  • @antoniocaioalmeidarosal1664
    @antoniocaioalmeidarosal1664 2 роки тому +2

    goshhh, this is perfect. Tks sooo much, kisses from brazil

    • @osmosis
      @osmosis  2 роки тому

      Most welcome, Antonio! 🥰❤️🙏🏼

    • @jameslight8746
      @jameslight8746 2 роки тому

      Having Shingles Virus is not the end of life , I got cured after using Doctor Ani John herbal supplement within 14days..

  • @dilonisabamf
    @dilonisabamf 3 роки тому +1

    Been sick for 5 months and can’t figure it out. Tested positive for ANA anti body’s and this video was super informative. Thank you

    • @soundsrelaxing888
      @soundsrelaxing888 2 роки тому

      I've been sick for 6 months and they just finally did a full panel and I tested positive for Ana

  • @danielpoblano2141
    @danielpoblano2141 7 років тому +6

    This is incredible, what recommendations could you give me to be a good researcher?

    • @skylark5789
      @skylark5789 6 років тому +6

      Study. Study your little heinie off! And read about one thing after another, like a trail of breadcrumbs that leads you to your answer. Oh, and Curiosity. Have it ALWAYS in your heart. You'll be great, I know, because you cared enough to ask. Looking forward to the great work you give to the world!

  • @JoshuaTraffanstedt
    @JoshuaTraffanstedt 2 місяці тому

    I just found out i had lupus today after getting a skin biopsy for a face rash last week. I got my blood taken after my dermatologist appointment and they said ill know in about a week what kind it is. Im hoping its the kind that just effects the skin. My younger brother gets that same face rash too, but he doesnt have insurance. I hope he finds a good job soon so he can go get checked.

  • @ivodelgado1433
    @ivodelgado1433 7 років тому +7

    First of all, Congrats i'm a big fan of your videos. As far as I know the anti-dsDNA and Anti-Sm are antinuclear antibodies as well, so, it should´t be described as "other autoantibody", am i right ?. Thanks for your videos !

  • @banuibrahim8676
    @banuibrahim8676 6 років тому +1

    Finally found an interesting way to study pathology... Really very helpful

  • @anasbitar1270
    @anasbitar1270 2 роки тому +67

    Welp, it's never lupus.

    • @enderan27
      @enderan27 7 місяців тому +16

      I have lupus. I made that joke when my doctor suggested it's lupus

    • @sleepydog9968
      @sleepydog9968 3 місяці тому

      ​@@enderan27you chill, respect 💪

    • @JoshuaTraffanstedt
      @JoshuaTraffanstedt 2 місяці тому +2

      ​@enderan27 a couple years ago I told My doctor my facial rash might be lupus and he said no because it wasn't a butterfly rash. It never is. Maybe it will be eventually. Needless to say, I found out today it is in fact lupus. I had to go to a dermatologist to find out.

  • @treasirewealth4024
    @treasirewealth4024 3 роки тому +1

    This is my consciousness tied to this channel actually-I came here to retrieve it-

  • @DSquad
    @DSquad 7 років тому +107

    All I know is Selena Gomez has it so I looked it up. Only one?? Ok

    • @subrinaonookdai5843
      @subrinaonookdai5843 4 роки тому

      Bruh same here

    • @easter.a1722
      @easter.a1722 4 роки тому

      Me

    • @aoibhetraynor8399
      @aoibhetraynor8399 4 роки тому +4

      I know same! I remember hearing her having a kidney transplant back in 2017 before I was a fan of hers. For some reason I got really interested and started looking up about lupus. After that I became a huge fan of hers. She's very opened about talking about lupus. I remember I felt really bad for her when I watched Selena and Chef and when she does her make up her hand keeps shaking because of her Lupus. She's going through so much and people still make fun of her illness. I think she's very inspiring about opening up about her mental health❤

    • @ralphkeeldar4726
      @ralphkeeldar4726 4 роки тому

      Sorry for her. You should know what to eat, and what not depending on your "immune system". I will cover this subject and other autoimmune diseases in my place on this website. Good luck !

    • @ralphkeeldar4726
      @ralphkeeldar4726 4 роки тому

      @@miriamkanana423 Hopefully you're feeling good. I will cover this topic one day in my place on this website.

  • @novu16
    @novu16 8 років тому

    man i just love your illustrations and the way you explain...it is better than all other videos i watched so far...i was really frustrated with my book and lecture ppt...thank you so much...

  • @MickeyTech
    @MickeyTech 3 роки тому +2

    Ooo this is the ANA test for lupus I heard in House md....

  • @stoneman2023
    @stoneman2023 10 місяців тому

    I have 10-11 Anti DS DNA, this video is really really helpful to understand what Lupus is, really great video, thank you thank you

    • @osmosis
      @osmosis  9 місяців тому +1

      Glad it was helpful! 🙏🏼

  • @aubreymagasoa9050
    @aubreymagasoa9050 7 років тому +6

    Thumbs up. This is very helpful.Thank you

  • @amkayss13
    @amkayss13 8 місяців тому +1

    I have had bad health for a while. Lots of pain, migraines & fatigue. I had a positive ANA test done last year. I went to a rheumatologist this year. Explained to her that I haven’t been getting any better. I thought I might have MS. She didn’t thinks so, she ran test for Lupus. Came back positive, the nurse from the Dr office called me with results. I am very disappointed in the Dr office though. The Dr didn’t make an appointment for me to come & discuss anything with her. The nurse called, said it was positive for lupus. I had so many questions, I know nothing about Lupus I explained. She said the Dr is putting on this med, & she will see you in 4 months! I left that phone call, crying & feeling so lost! I am now looking for a new rheumatologist Dr. one who has compassion for there patients! I had to fight for these Dr to make them run test! It’s sad that we have to be our own advocates! Thank you for this video. I have watched a few videos on Lupus, this by far the best. Explaining everything about this disease. ❤️‍🔥🫶🏽🙏🏽

    • @osmosis
      @osmosis  8 місяців тому

      Thank you for your feedback 🙏🏼

  • @emresusammd
    @emresusammd 7 років тому

    the best video for understanding how is going on in this disease.

  • @jamiesuzette666
    @jamiesuzette666 8 років тому +4

    thank you for this well informative video. I have been trying to explain these things to ppl for a very long time. Diagnosed in 1992....
    I posted this on my Facebook page, and I know it will be viewed there.

    • @osmosis
      @osmosis  8 років тому +1

      Thanks!

    • @baboom007
      @baboom007 6 років тому

      Hey. My mother was Diagnosed 2 month ago. How do you get through this. How are you feeling. Can u live with this?

  • @saisandeep4292
    @saisandeep4292 7 років тому

    I studied in robins but i couldn't understand it. after watching this video i got much clarity.
    Thank you very much.

  • @gloriabrill
    @gloriabrill 3 роки тому +5

    What if the environmental factor was the Covid vaccine? Has anyone come down with heart inflammation with/or Lupus after vaccination?

    • @Dnlsx777
      @Dnlsx777 Рік тому

      I have sle and I didn't die from taking MNRA. I refused it. Thank you God. I am having a flare. Discord rash, and I stay in and take Cell Cept Prednisone plaquinil. Also Short of breath and back pain.

  • @ellaelliott4415
    @ellaelliott4415 2 роки тому +2

    I was diagnosed maybe five or six years ago. Gah, it was so hard to get a diagnosis because it mimicked everything else. My first symptoms were excruciating joint pain, severe sun sensitivity (my body would break out in hive-like bumps at minimal sun exposure) and debilitating fatigue. I was lucky enough to find a brilliant medical team, and I owe everything to them, including their decision to put me on hydroxychloroquine instead of steroids. My organ functions are better than I thought they would be, but I am worried about my kidneys, and my calcium is way, way, way too high for some reason, and that can cause liver damage. Though things have changed since this video came out, it's still a great explanation of what SLE is without throwing keywords and terms at you that aren't understandable.

    • @sena9671
      @sena9671 2 роки тому

      glad you are better.

    • @abhinavsuman2366
      @abhinavsuman2366 2 роки тому

      Hope you are are fine and doing well. My sister-in-law is also suffering from this problem since 2017.