Metastatic breast cancer | Stage IV breast cancer | Best Oncologist in Kolkata

Metastatic breast cancer: Is it the end?
What is metastatic breast cancer?
Metastatic breast cancer is a stage of cancer when cancer cells have spread from the breast to other parts of the body. It is also called advanced breast cancer or stage IV breast cancer.
What investigations are done before starting treatment in such patients?
• History taking including family history of any cancer
• Clinical examination
• Baseline blood tests
• Biopsy
• Estrogen receptor, Progesterone receptor, HER2Neu receptor and Ki-67% on biopsy sample
• PDL1 status on biopsy sample
• Some times we check for mutations like PIK3CA, BRCA 1& BRCA 2.
• CT scan of chest, abdomen, Pelvis
• Whole Body PET-CT scan
• MRI brain when suspecting cancer spread to brain
• 2D-Echocardiography before using particular targeted therapy
What is the prognosis of metastatic breast cancer?
Metastatic breast cancer is usually incurable. The aim of treatment at this stage is to try to control the cancer, try to control the symptoms from cancer, and try to improve the quality and quantity of life. A limited subgroup of patient called Oligo metastatic disease (Small or limited spread to other organ) can be treated with curative intent.
What are the treatment options for metastatic breast cancer?
Treatment of metastatic breast cancer depends on many factors: Age, medical comorbidities, fitness for treatment, symptom of the patient, Estrogen receptor/ Progesterone receptor/ HER2Neu receptor/ Ki-67 receptor status/ PDL1 level, PIK3CA mutation status etc. Treatment options for metastatic breast cancer patients include-
1. Hormone therapy which can be in oral form or injectable form
2. Chemotherapy
3. Targeted therapy
4. Immunotherapy in selected cases of triple negative breast cancer with PDL1 positive status.
5. Sometimes palliative radiotherapy may be needed for symptom control
6. Role of surgery is usually limited at this stage.
How oligo metastatic breast cancer is treated?
Oligometastatic disease means limited cancer spread to different organ. This group of patients are usually treated with curative intent. The treatment usually involves surgery, chemotherapy, radiotherapy, hormone therapy, targeted therapy in various combination. Area of limited cancer spread (oligo-metastatic spread) in any organ like lung, liver, brain or bone; can be treated with stereotactic ablative body radiotherapy (SABR) or stereotactic radiosurgery (SRS). Stereotactic ablative radiotherapy is technique for delivering accurate and precise external beam radiotherapy to a cancer, using high doses per session and usually in 1-8 treatment fractions. When the same technique of radiotherapy is delivered in single session to specific sites like brain or spine etc; it is called stereotactic radio surgery or SRS.

[@somiruddinkhan2478]

Please sir make a video about non metastatic triple negetive breast cancer.

[@dranimeshsaha3365]

Thanks for your message. We will try to make one on this topic

[@kirandas4967]

Sir meri mummy ko bhi stage 4 metastatic breast cancer hua h dr ne 6 palliative chemo therapy ke liye bole h uske aage kya hoga bta sakte h sir plzz meri help kariye

[@OHFriendly]

I had CA last 2 years and followed up every year.Last month I found birad 4b and ster. biopsy as fibrocystic change with benign intraluminal and epithelial calcification.Would u pls. tell me that I will have CA second time? Thx.

[@dranimeshsaha3365]

Thanks for your comment. It is advisable to follow up with your treating consultant at regular interval. You can consult Dr. Animesh Saha online through Apollo 24/7 app www.apollo247.com/doctors/dr-animesh-saha-d6dc9443-bf2a-4f6a-a7b0-f52b8e7b6d10. For OPD consultant please call Mr. Sanjit Das on 8777427312.

[@kirandas4967]

Aur hm mummy ko Tata medical centre se treatment krwa rahe h

[@ashimamohapatra8242]

Sir pTNM staging -pT2N1aMx what stage it is?

[@dranimeshsaha3365]

Thanks for your comment. It is advisable to discuss with your treating consultant. Mx means we have not done sufficient investigations to know whether the cancer has extended beyond breast and axillary lymph nodes. You can consult Dr. Animesh Saha online through Apollo 24/7 app www.apollo247.com/doctors/dr-animesh-saha-d6dc9443-bf2a-4f6a-a7b0-f52b8e7b6d10. For OPD appointment contact Mr. Sanjit Das on 8777427312.

[@daa4448]

Stage 2 lymph nodes positive breast cancer which type CHEMOTHERAPY is best AC YA TC?

[@dranimeshsaha3365]

Thanks for your query. There are plenty of factors to consider before we decide a chemotherapy regimen. Please discuss with your treating consultant.

[@krishnagopalprasad354]

Any other places apart from Apollo?

[@dranimeshsaha3365]

No, I don't practice outside Apollo as of now

[@meenabalasubramanian6483]

ER/PR positive and Her2 negative metastatic cancer curing possibility

[@dranimeshsaha3365]

Thanks for your query. Usually metastatic breast cancer patients irrespective of ER/PR/HER2Neu status is incurable. However ER/PR+ HER2neu patients usually have a better prognosis and can be controlled long term with available treatment. There is a small subgroup of patients called Oligometastatic disease, which means small / limited spread to other organ. This group of patients can be treated with curative intent.

[@NehaKumari-hr6yj]

My mon had breast cancer after two years its spread in bones ,hert2 positive is it possible to cure???

[@AnjaliSharma_07484]

Kya symptoms aaye the aapko mummy ko meri mummy ke breast cancer h kal unke ak leg me bahut jyada pain hua tha
Plzz reply

[@helensworld2296]

Meri Ami ko b Tha ..phly koi symptom Ni ay or ak month uny right Aram m pain houa both Zayda ..or 1 month bad un ke death ho gye

[@shruthikarnati4865]

Sir can I send my pet scan report so that u can advise how my treatment going on I am metastatic breast cancer

[@dranimeshsaha3365]

Thanks for your query. You can consult me at Apollo Multi-Speciality Hospital Kolkata or online through Apollo 24/7 app.

[@shreyanshraj688]

How are you now??

[@shruthikarnati4865]

Fine

[@sowmyabn3634]

My mother in law has T2N3aMx and richerdson score 3+2+2 which stage is this

[@dranimeshsaha3365]

Thanks for your comment. Mx means sufficient information has not been done to confirm the stage. Richadrson score represent the grade of the cancer i.e, how aggressive the cancer is. Score 3+2+2 means Grade 2 or intermediate grade. For more details please speak to your treating consultant. You can consult Dr. Animesh Saha online through Apollo 24/7 app www.apollo247.com/doctors/dr-animesh-saha-d6dc9443-bf2a-4f6a-a7b0-f52b8e7b6d10
For OPD consultation and appointments call Mr. Sanjit Das on 8777427312.

[@sowmyabn3634]

@@dranimeshsaha3365 thankyou sir

[@user-wm4qr9uw1q]

Very good video sir thanku...Kanchnaar guggul by Planet ayurveda are really good results on Breast cancer.

[@ush609]

Sir mera breast ultrasound mean birads 4A aaya

[@dranimeshsaha3365]

Thanks for your message. Please consult with an Oncologist. You can consult me at Apollo, Kolkata ( Please contact my secretary on 8777427312 to book your appointment. You can also consult me online through Apollo 24/7 app , link provided below www.apollo247.com/doctors/dr-animesh-saha-0bd00d29-4590-42e1-aa99-1dd85b36fd09.