Dr Sam Banister - Psychedelics 2.0 and beyond

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  • Опубліковано 16 лип 2024
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    Dr Sam Banister - Psychedelics 2.0 and beyond
    In the past decade, there has been an explosion of research focused on the medicinal chemistry of psychedelics. Dozens of companies around the world are developing entirely new psychedelic medicines for the treatment of serious mental health disorders.
    Modern psychedelic drug development utilises the most cutting-edge scientific technologies and is illuminated by insights from psychedelic-receptor interactions obtained at an unprecedented level of detail using cryogenic electron microscopy and molecular modelling.
    The presentation will describe the rational development of entirely new classes of psychedelic drugs being employed by leading academic laboratories and private companies and what these new medicines will mean for the most desperate patients.
    00:00:00 Introduction
    00:01:39 Clinical studies of psychedelic medicines
    00:03:51 Phenethylamines, ergolines and tryptamines
    00:04:32 Optimising psychedelics for therapy
    00:06:39 How psychedelics work in the body
    00:07:15 Serotonin (5-HT) receptors
    00:09:08 Heart disease and 5-HT2B agonism
    00:10:49 Future of psychedelic medicine
    00:12:15 Psychedelic drug development
    00:16:32 Psychedelic neuroplasticity
    00:19:03 Psychedelic head twitch response in mice
    00:21:43 Virtual reality, computational chemistry, psychedelic receptor and drug modelling
    00:23:20 Q&A
    Bio
    Dr Sam Bannister is currently CSO of Psylo; a biotech start-up focused on the development of next-generation psychedelic medicines. Sam has been developing new therapeutics in the fields of neuropsychiatry and neurology for more than 15 years at leading academic institutions (Stanford University, University of Sydney, UNSW) and biotech start-ups (Tranquis Therapeutics, NaluBio). Prior to founding Psylo, he was Team Leader in Medicinal Chemistry at The Lambert Initiative for Cannabinoid Therapeutics, and was a postdoc at Stanford University studying cannabinoids, psychedelics, and new psychoactive substances (NPS) before that.
    His work on the chemistry and pharmacology of new psychoactive substances (sometimes called "research chemicals") has been covered by major newspapers (New York Times, Sydney Morning Herald) and national radio programs (NPR). Sam is an enthusiastic science communicator, appearing as a guest on numerous science podcasts, and regularly presents at community science events such as Pint of Science, National Science Week, Vivid, and The Science Tent at Splendour in the Grass.
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    About EGA.
    Entheogenesis Australis is a charitable educational organisation established in 2004. We provide opportunities for critical thinking and knowledge sharing on ethnobotanical plants, fungi, nature, and sustainability. Through our conferences and workshops, we aim to celebrate the culture, art, politics and community around medicine plants in the hope to better wellbeing for humankind and the planet.
    To find out more about what we do, head over to our organisational website, www.entheogenesis.org. Also, head to the conference website for more info - www.gardenstates.org

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