Prof. Grant Schofield - 'Glutamate: why it might matter'

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  • Опубліковано 14 гру 2024

КОМЕНТАРІ • 73

  • @cassieoz1702
    @cassieoz1702 Рік тому +29

    Thomas Seyfried has written at length on anaerobic glutamine fermentation as one of the obligatory energy pathways in cancer cells. We need more research on access to therapeutic glutamine-glutamate targeting

  • @BiggieCheese45
    @BiggieCheese45 Рік тому +14

    Very interesting. The food list for Glutamate is pretty big. Important to Fast and do Low carb. Important to avoid processed and artificial junk foods. That paper on Low Glutamate Diet on Gulf War Syndrome is gonna help people understand that diet does indeed play a big role of dietary nutrition on affecting mental health

    • @lorimav
      @lorimav Рік тому

      Watch out for Roquefort and Parmesan and even tomato sauce! I knew my autistic daughter got highly agitated with MSG and the types of things it was hidden under and even the soy sauce but I had no idea the daily blue cheese on her salad or the Grana Padano with tomato sauce on pasta was also very high in natural glutamates. I didn't even learn about the connection between autism and glutamates until I was searching for why she was getting a very bad reaction to glycine that I was trying as a sleep supplement plus magnesium glycinate. My source stated that glycine bothered some people with glutamate sensitivity. What surprise me was that this was in an autism related site. I guess glutamate can cause problems for others with autism too.

    • @KiwiBee21
      @KiwiBee21 2 місяці тому

      @@lorimavmagnesium glycinate ? 💡

    • @steshaw6510
      @steshaw6510 Місяць тому

      ​@@KiwiBee21yes, it would have been magnesium glycinate. Magnesium bonded with glycine.

  • @bob-ss4wx
    @bob-ss4wx Рік тому +18

    Open and honest, can't ask four more!

    • @adelarsen9776
      @adelarsen9776 Рік тому +5

      Just ask for three more then...

    • @defeqel6537
      @defeqel6537 Рік тому +2

      how about three more?

    • @chazwyman8951
      @chazwyman8951 Рік тому

      Two more too

    • @ChefJollyRoger
      @ChefJollyRoger Рік тому

      ​@@defeqel6537 he is making a joke because the first comment said "four" and not "for. 😅

  • @6789uiop
    @6789uiop Рік тому +25

    I'm interested in the glutamine glutamate pathway feeding cancer tumor growth, along with glucose.

  • @汗をかいたアヒル
    @汗をかいたアヒル Рік тому +5

    If Grant was Health Minister or dang it, Prime Minister of NZ it would be a fantastic place to live!

  • @chrissiemsolomanpt2157
    @chrissiemsolomanpt2157 Рік тому +7

    Grant can hardly be blamed for not knowing about glutamate before 'Chrissie' mentioned it. Glutamate is not typically covered in psychology courses. I stumbled across it while trying to learn more about the serotonin connection. I read a book about the neurology of mental illness which covered glutamate extensively, while serotonin was nowhere to be seen. The glutamate connection has been known about since the early eighties but not widely popularised in mental health treatments. Hardly surprising when the production and sale of psychotropic medications is based on the now debunked serotinin hypothesis.

  • @RoosKohn
    @RoosKohn Рік тому +11

    So funny. I heard d*ck head when he said decade. Took a while but I had a laugh that helped wrapping my mind around government and science guidelines in the light of this amazing lecture. Thank you so much. 🙏❤️🌹

  • @Keithzzzzt
    @Keithzzzzt Рік тому +1

    Wow. That was a fantastic talk .

  • @crcharrt917
    @crcharrt917 Рік тому +17

    Wow! I knew for many years that the disfunction of glutamate caused neurological problems. But in my deep dive to become metabolically healthier, due to familial motor neurone disease in my family. I think this is the clearest indication yet of the link between mitochondrial damage and toxicity caused by diet and lifestyle. It's a big wake up call for me and I hope changes healthcare from base level up.

    • @LadyGreyAgeingDisGracefully
      @LadyGreyAgeingDisGracefully Рік тому +4

      I work in healthcare and have seen for myself the resistance to change despite the evidence presented. This personal experience has meant I don’t rely on the system to make choices for me or nor do I expect them to provide all the choices. My GP was highly critical of my carnivore diet. I have provided her much research and she is softening. I wouldn’t say she’s at the point of recommending the diet. But at least she’s considering the research which is more than those I work with in public health.

    • @Unsensitive
      @Unsensitive Рік тому +2

      I was diagnosed bipolar over 20 years ago.
      Eventually I identified the root cause as poor sleep, later identifying myself as having sleep apnea.
      By dietary change I reduced my sinus inflammation and eliminated my sleep apnea.
      Combined with the healthier diet as a potential confounder, I've been off meds now with zero issues and stable mental health for over 15 years.

  • @adelarsen9776
    @adelarsen9776 Рік тому +9

    Great metabolic health comes from human behavior and that includes eating human food.

  • @il3mendo
    @il3mendo 4 місяці тому

    Thank you doctor.

  • @madcatter972
    @madcatter972 Рік тому +12

    Very interesting info. Totally agree with your viewpoint on prevention. So much focus seems to be on managing symptoms (with meds upon meds) & not looking at he root causes. I have hashimotos & my GP refused to test for thyroid antibodies initially as it wouldn't change the treatment (t4 meds). However it's vital to know what's driving hypothyroidism. If it's autoimmune the thyroid will continue to be destroyed until it's basically rubber, & it's likely more autoimmune conditions will follow if the cause of stress & inflammation i.e. what's driving the autoimmune response isn't found & dealt with. That might be adrenal fatigue, nutritional deficiency, leaky gut/poor gut health, food or environmental sensitivities etc etc.

    • @LadyGreyAgeingDisGracefully
      @LadyGreyAgeingDisGracefully Рік тому +4

      That’s disappointing and highly predictable response from a doctor. Treat the symptoms and not the cause has become the mantra of modern medicine.

    • @madcatter972
      @madcatter972 Рік тому +2

      @@MajesticArtimus as per my comment, my GP refused to test anything INITIALLY. I've had to fight for many tests & treatment.

  • @andrewclark3236
    @andrewclark3236 Рік тому +6

    I ate a packet of cheap store brand potato chips, possibly salt n vinegar, that night I had nightmares all night.

  • @jobrown8146
    @jobrown8146 Рік тому +14

    I became hooked on Pringles Sour Cream and Chives chips (this was back in the 1990s well before I went low carb - Oct 2021) and became* glutamate intolerant* (proven by an elimination diet and weekly food challenge). Six hours after consuming MSG I would get severe diarrhea which smelled really bad and become very weak with an extremely fast heart rate, sweating and hives. After the food challenge I went on a low glutamate diet for several years and after that time I was able to introduce small amounts of high/er glutamate foods.

    • @wocket42
      @wocket42 Рік тому +5

      Good you see some improvement. When seeing the slides of foods to avoid due to high glutamate content and success in trials, I wonder if the same effect could be achieved "just" by fixing leaky gut and leaky blood brain barrier. So, if you are healthy to start with it's probably not necessary to avoid glutamate in the diet, but to avoid a high glutamate/pro leaky gut diet. Like eating lots of pringles with either a high sugar soda or a diet soda.

  • @jennyweyman3039
    @jennyweyman3039 Рік тому +1

    Fascinating

  • @toni4729
    @toni4729 Рік тому +2

    Very interesting chap. Thank you.

  • @pointshealthcoaching8474
    @pointshealthcoaching8474 Рік тому +3

    I learned a lot
    Thx

  • @pepper419
    @pepper419 Рік тому +1

    Thank you. Very interesting indeed.

  • @汗をかいたアヒル
    @汗をかいたアヒル Рік тому +2

    Grant has not aged in 10 years I have known him!

  • @sabincioflec8413
    @sabincioflec8413 Рік тому +5

    min 29:44 i'd say that creatine has an effect since it spares glycine and glycine will be turned into more glutathione

    • @borealmat1889
      @borealmat1889 Рік тому

      So is it good? I don't get it 😅

    • @AnneAlready
      @AnneAlready Рік тому

      @@borealmat1889 Yes if it spares glycine. x

  • @Tad-For-Global-Peace
    @Tad-For-Global-Peace 6 місяців тому

    Ty

  • @jaybanks7718
    @jaybanks7718 Рік тому +5

    Avoid broccoli and walnuts. Sometimes I wonder about the end game here. I kind of imagine we will just quit eating and walk around with an IV drip of grass-fed butter. Mmm, mmm good.

    • @serendipityblooming1244
      @serendipityblooming1244 Рік тому +1

      Haha i feel you! The carnivore diet might be worth a shot :) Its been tremendous for me, an ex vegan!

  • @chazwyman8951
    @chazwyman8951 Рік тому +1

    Driving me nuts and Shazam can't find it. What is the tune the vids begin and end with? Anyone know?

    • @ruth2339
      @ruth2339 Рік тому +7

      Sevilla by Albéniz

  • @freespirit6209
    @freespirit6209 Рік тому +1

    👍👍👍

  • @viviendavenport7601
    @viviendavenport7601 3 місяці тому

    Why the Hawaii remark? I live there and it is an amazing life. People are quite nutritionally, community, and environmentally aware. I should say, a walk about a desert with kangaroos is no life. All though you insulted my home I will not do a Haka. I subscribed anyway. Good info. Aloha 😊 . Someone should do a study on poi. It is a p.h. neutral starch an infant can eat. How is it metabolized, insulin reactivity etc ?

  • @Norman_Gunstan1
    @Norman_Gunstan1 Рік тому +1

  • @dmackle3849
    @dmackle3849 Рік тому +1

    Good work as usual LCDU.
    Great to hear Grant getting air time, seems like a sensible kiwi.
    The Julia Rucklidge approach is interesting, although a little too forgiving of phytotoxicity; but whomever is responsible for that periodic table breakdown (15:46) has made a serious omission not including Lithium.
    ua-cam.com/video/sA8AtSWPnRw/v-deo.html

  • @bernhardjordan9200
    @bernhardjordan9200 Рік тому

    Cool

  • @rangagrips7156
    @rangagrips7156 8 місяців тому

    the mental health of parents from false accusations in family court is disturbing. one one person can claim from false accusations with no accountability is disgusting. false claims to DCP and police for made up actions to force investigation with no action taken against the perpetrator leave parents running scared and anxious to live their lives. This theory while not looking at the environmental factors and proving claims while thinking that a chemical imbalance must be the reason for a perfectly normal human response to a fraud system is laughable at best.

  • @williammorgan7769
    @williammorgan7769 Рік тому +5

    🧈

  • @notesfrommateriality7572
    @notesfrommateriality7572 Рік тому +4

    switched off when he said he was a professor of public health. After the last few years I'll never listen to a word from a guy with that title

    • @marianne1959
      @marianne1959 Рік тому +3

      Interesting....I had the same thought. 😮
      Came to comments section to see what others had to say about his presentation.

    • @AynRandfan1957
      @AynRandfan1957 Рік тому +5

      I agree. Anyone who kept their job in public health in NZ through the plandemic is not worth listening to and needs to spend some time listening to Mark and Sam Bailey.

    • @iss8504
      @iss8504 Рік тому

      Yup I had the same thought. Nope.

    • @hiraijo1582
      @hiraijo1582 Рік тому +2

      @@marianne1959 as a MD in austria i experienced what you see in any profession. in austria there are some very smart people in public health and others who do a bad job. unfortunately it is mostly the latter who move up the ladder.

    • @wally6193
      @wally6193 Рік тому +6

      true enough, it's even harder now to trust anyone from the gov health departments, let alone GPs in general.