Extensive Medicine
Extensive Medicine
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Tecovirimat (TPOXX) for MPOX Treatment
Tecovirimat, also known as TPOXX, is the first antiviral treatment approved for smallpox, and it's making strides in treating orthopoxvirus infections like mpox (monkeypox). In this video, we provide an in-depth review of the mechanism of action, clinical uses, dosing, and side effects of tecovirimat, along with its role in managing emerging viral outbreaks. With growing concerns over zoonotic diseases and bioterrorism, understanding tecovirimat's efficacy and safety profile is essential for healthcare providers. Learn how tecovirimat targets the VP37 envelope protein to inhibit viral spread, making it a vital tool in orthopoxvirus management. Whether you're a clinician looking to expand your knowledge on antiviral agents or preparing for upcoming cases of viral infections, this video provides high-yield, evidence-based information. Stay updated on the latest CDC guidelines and FDA approvals for tecovirimat. Subscribe for more medical insights!
#tecovirimat #TPOXX #mpox #monkeypoxcases #mpoxoutbreak
This video is NOT sponsored. Some product links are affiliate links, which means if you buy something, we'll receive a small commission.
======================================================
Buy the best medical text books we follow (affiliate links):
======================================================
1. Harrison's Principles of Internal Medicine, Twenty-First Edition (Vol.1 & Vol.2) : amzn.to/4bEumzN
2. Davidson's Principles and Practice of Medicine 24th Edition: amzn.to/3VZHTfF
3. Kumar and Clark's Clinical Medicine 10th Edition: amzn.to/3Y1wM8M
4. First Aid for the USMLE Step 1 2024 34th Edition: amzn.to/4cZTZft
Books on mpox (monkeypox):
1. The Scientific Basis of Mpox (Monkeypox): amzn.to/46UJyrU
2. From Monkey Pox To Mpox : amzn.to/3Xh73Ze
3.MPOX; The Silent Spread: amzn.to/3Z15YWm
===========================
⏰ Timecodes ⏰
===========================
00:00 - Introduction
00:22 - Mechanism of action of tecovirimat (tpoxx)
00:40 - tecovirimat pharmacokinetics
00:59 - Use of tecovirimat
01:28 - Tecovirimat dose for mpox
02:03 - Dose adjustment for kidney impairment and liver impairment
02:16 - Adverse effects of tecovirimat
02:27 -Contraindications of tecovirimat
02:42 - Evidence for use in mpox
02:59 - Product availability for mpox
03:09 - Tecovirimat in pregnancy and breastfeeding
03:18 - References
===========================
Links for Related Videos:
===========================
1. What is MPOX? : ua-cam.com/video/dOaErI8hPck/v-deo.html
2. EEE : ua-cam.com/video/KJQUrx-Q9wo/v-deo.html
===========================
Links for related playlists:
===========================
00: Pharmacology: ua-cam.com/play/PLbilivK1P_9KdQcAgVbwzN_GkSsYdh5lq.html
0. Infectious Disease: ua-cam.com/play/PLbilivK1P_9IoqWlqJC_S6IGtqxeEESuV.html
1. Mnemonics:ua-cam.com/play/PLbilivK1P_9LxDii1hRMDej0BspYPu6ai.html
2. High Yield: ua-cam.com/play/PLbilivK1P_9KrZLVym2_xeIeGjlpQ4SJP.html
3. Simple Explanations: ua-cam.com/play/PLbilivK1P_9IgDVBrE5XMojpEfrDrZUnu.html
4. Clinical Signs: ua-cam.com/play/PLbilivK1P_9LlONCaOSDDdUHTdnU8XkpN.html
5. Lectures: ua-cam.com/play/PLbilivK1P_9JDMfiInhZN1UmcAtYbbEPC.html
6.Gastroenterology: ua-cam.com/play/PLbilivK1P_9LgsoOnRJAKTh3hjOc81xqH.html
7. All Playlists: ua-cam.com/users/view_all_playlists
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===========================
Medical disclaimer!
===========================
Extensive Medicine (EM) does not provide medical advice. EM does not provide a diagnosis or other recommendation for treatment and is not a substitute for the professional judgment of a healthcare professional in the diagnosis and treatment of any person. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.
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КОМЕНТАРІ

  • @RSGC
    @RSGC 8 днів тому

    Thank you very excellent extensive simplified overview of mpox 2024

  • @eshalkhankakar4607
    @eshalkhankakar4607 22 дні тому

    Corona virus is spherical

  • @sapanaghimire9855
    @sapanaghimire9855 Місяць тому

    Very informative and helpful video.Thank you😊

  • @ngugichecha1615
    @ngugichecha1615 Місяць тому

    WOUNDERFUL

  • @GOPIKAK-wv4ln
    @GOPIKAK-wv4ln Місяць тому

    Bethesda 4 cancer ano

  • @preethi_.m1122
    @preethi_.m1122 Місяць тому

    Thank you so much sir!

  • @arshrana1786
    @arshrana1786 2 місяці тому

    Bethesda 5

  • @ExtensiveMedicine
    @ExtensiveMedicine 2 місяці тому

    Corrections: 1. Ruffini's corpuscles: They are encapsulated (video says they are not capsulated).

  • @RAJYASREE-x6z
    @RAJYASREE-x6z 2 місяці тому

    Sir / maddam. Thus. Helping. The care of. That the. Care that the help the. Life is. Pills. In the care is. Given. Then. This. Stops. Then the care is. For. Ten. Minutes. As well. Thus the. Care is. That the life is. So that the life is. So. That the help the. Lifelore. That the. Care as well. Thus. This. Is. No. Dindore to. Sare the. Life as well. Thus this help to help this. Is. Life is that is. Then. Finger clasping. Hand rotator. Finger ladder. Thus. Helping. The life as well. Thus help the care too. Now the. Medically the life is that the help the. Siresore. As well. Ie. Thus. Helping the. Opening closing the. Clasp. Thus. The. Finger rehab. Thus to help the care to help the life is that the. Care as well. Thus help. Thanks. Sir/ maddam 😊

  • @MadeAlive778
    @MadeAlive778 2 місяці тому

    So straight to the point. Thank you

  • @AbdulRazakSulaiman-v1s
    @AbdulRazakSulaiman-v1s 2 місяці тому

    Bethesda / 3

  • @dr.monaliwaghchaure6692
    @dr.monaliwaghchaure6692 3 місяці тому

    Thank you so much

  • @woyubryna2118
    @woyubryna2118 3 місяці тому

    Simply amazing 😊😊😊

  • @sosomuse9122
    @sosomuse9122 3 місяці тому

    Thanks alot sir you don't know how much you helped me <3

  • @linda-xv2xs
    @linda-xv2xs 3 місяці тому

    And ............... jelly?

    • @ExtensiveMedicine
      @ExtensiveMedicine 3 місяці тому

      Please check full video from our channel for more details.

  • @UNSyed
    @UNSyed 3 місяці тому

    GREAT!!

  • @tristyhawn1651
    @tristyhawn1651 4 місяці тому

    That's looks like a tongue tremmor, not a faciculation.

  • @drprasansh
    @drprasansh 4 місяці тому

    THANK YOU SO MUCH

  • @zerof1593
    @zerof1593 4 місяці тому

    Got bethesda 3/4 is tgat bad

    • @ExtensiveMedicine
      @ExtensiveMedicine 3 місяці тому

      You should consult with your doctor for an expert opinion.

  • @ramosman0469
    @ramosman0469 4 місяці тому

    Do these tremors get worse as you age?

    • @ExtensiveMedicine
      @ExtensiveMedicine 4 місяці тому

      Usually they they don't but they can be aggravated by certain factors like drugs, anxiety, thyroid dysfunction etc.

    • @ramosman0469
      @ramosman0469 4 місяці тому

      @@ExtensiveMedicine thank you for your response.

  • @sapanakoyatra
    @sapanakoyatra 4 місяці тому

    Very useful video 👍🏼

  • @sapanakoyatra
    @sapanakoyatra 4 місяці тому

    This is great.keep uploading such real cases video.

  • @dineshraja7121
    @dineshraja7121 5 місяців тому

    Super! Thank you!

  • @JacobAlbert-u2m
    @JacobAlbert-u2m 5 місяців тому

    Still very thankful to drohanon for helping me and my partner get rid of bad breath now we are both cured completely and the medical doctor also confirmed it.,,👍

  • @user-je2cc9qn6t
    @user-je2cc9qn6t 5 місяців тому

    Please what type of tremor is seen in thyrotoxicosis

  • @doconerr
    @doconerr 6 місяців тому

    Thakyou sm

  • @swapnilzaveri4271
    @swapnilzaveri4271 6 місяців тому

    My skin becomes dark . I have 190 .. in vitamin B12 deficiency How should I take care

  • @dhanushree_m
    @dhanushree_m 6 місяців тому

    Traps mnemonic

  • @Jay-uo1sn
    @Jay-uo1sn 6 місяців тому

    I just started getting tongue tremors I usually just get mouth tremors where my mouth would move left and right in a rhythm movement

  • @indiancitizen3013
    @indiancitizen3013 7 місяців тому

    Hello sir. I'm 26 years old. My doctor said only 3 vaccine need to be vaccinated initially. Your video shows 4 vaccine.

    • @ExtensiveMedicine
      @ExtensiveMedicine 7 місяців тому

      Usually, 4 vaccines are indicated. 3 vaccines ( for prevention of bacterial infection) + 1vaccine( annual influenza virus vaccine).

    • @sksrabon8573
      @sksrabon8573 6 місяців тому

      Will I have any problems because I was given the vaccine 14 days after my open splenectomy surgery?

    • @sksrabon8573
      @sksrabon8573 6 місяців тому

      ​@@ExtensiveMedicineWill I have any problems because I was given the vaccine 14 days after my open splenectomy surgery?

    • @indiancitizen3013
      @indiancitizen3013 6 місяців тому

      @@sksrabon8573 Which vaccine did you take can you please tell me. I'm going for surgery

    • @ExtensiveMedicine
      @ExtensiveMedicine 5 місяців тому

      @@sksrabon8573 Ideally vaccine should be given prior to surgery. However, If vaccine cannot be given prior to surgery, it is usually initiated after the surgery. There won't be much difference.

  • @happiness965
    @happiness965 7 місяців тому

    Thank youu

  • @man_ish1234
    @man_ish1234 7 місяців тому

    Very useful thanks !😊

  • @mariancrist
    @mariancrist 8 місяців тому

    Promo`SM

  • @fayerfayer3814
    @fayerfayer3814 8 місяців тому

    Omg this did not help at all

    • @ExtensiveMedicine
      @ExtensiveMedicine 8 місяців тому

      Really?

    • @jessicaronald8971
      @jessicaronald8971 2 місяці тому

      Wolf Chaikoff phenomenon is normal, when given excess iodine, TSH reduces and hence T3,T4 do too. But in Jod Basedow phenomenon, excess iodine actually increases TSH and thereby T3,T4 in people with iodine deficiency, for example when a person with endemic goitre starts taking iodine. This occurs cuz of loss of negative feedback from T3 T4 on thyroid gland

  • @keitymarley733
    @keitymarley733 8 місяців тому

    Parkinson disease is a very terrible illness, my Dad suffered from it for 19 years until we finally got a help and a medicine that truly works that helped treat, cure and reversed all his symptoms• My Dad is completely okay and healthy now.

  • @ShifanawazWellnessPlaceForYou
    @ShifanawazWellnessPlaceForYou 9 місяців тому

    Thank you very much. A much needed video. 👍 😂

  • @informationforu112
    @informationforu112 10 місяців тому

    Urdo wich pein yah le

  • @yumrecipesnew
    @yumrecipesnew 10 місяців тому

    Very informative 😊

  • @muhammadsulaiman3353
    @muhammadsulaiman3353 10 місяців тому

    Ppt please

  • @mdabdullahalhossain1008
    @mdabdullahalhossain1008 10 місяців тому

    Y not use "parts"

  • @user-ec1uy8jl3i
    @user-ec1uy8jl3i 10 місяців тому

    Thanks 👏🏻❤️❤️❤️❤️

  • @anjalijain9809
    @anjalijain9809 10 місяців тому

    Thankyou

  • @ahmedbenlahrech5352
    @ahmedbenlahrech5352 10 місяців тому

    I have an issue with these signs, concidering the astonishingly low sensitivity and specificity, why do we take them seriously in the first place ? especially now that evidence based medicine is the new hot thing

    • @ExtensiveMedicine
      @ExtensiveMedicine 10 місяців тому

      History and clinical examination compliments the evidence based medicine. So, it's very important to know the clinical signs.

  • @mrmc55
    @mrmc55 10 місяців тому

    Life saver ...❤

  • @alyasajamei3570
    @alyasajamei3570 11 місяців тому

    Thank you a lot for the brilliant mneomonic and linking ❤

  • @meermurtaza2558
    @meermurtaza2558 Рік тому

    grateful Sir

  • @beatricedouglas7081
    @beatricedouglas7081 Рік тому

    Great! Thanks!

  • @aliaaahmed7544
    @aliaaahmed7544 Рік тому

    Great thank you

  • @chuckhere
    @chuckhere Рік тому

    how to relieve these tremors?

    • @ExtensiveMedicine
      @ExtensiveMedicine Рік тому

      There are many treatment methos. You should consult a neurologist for the treatment.

  • @Gandalf-DZ
    @Gandalf-DZ Рік тому

    Love it. Can't see how i could forget it after this. THANK YOU