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Aspergillus & Aspergillosis
Приєднався 1 бер 2016
Aspergillus is a group of fungi that are extremely common throughout the world living on all the organic detritus generated by life and death - mainly in the plant world. Only a few species can grow at our body temperature, but those that can can infect us, usually if our immune systems are defective or in the case of some people who have immune suppression in order to have a transplant (e.g. bone marrow transplant), no immune system at all.
If they get a foothold they can continue to grow and will cause aspergillosis in rare cases.
If they get a foothold they can continue to grow and will cause aspergillosis in rare cases.
Fibreoptic Bronchoscopy (June 2002)
Kindly provided by Dr Ronan O’Driscoll and with thanks to Dr P Barber, Bronchoscopy Unit, Wythenshawe Hospital, Manchester.
Copyright Dr R. O’Driscoll.
Copyright Dr R. O’Driscoll.
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Відео
A Fine Needle Biopsy of the Lung (June 2002)
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Produced by David Denning and described by Dr Rob Bissett. With kind permission of Gardiner-Caldwell, funded by Janssen-Cilag. Copyright Aspergillus Website.
AAAM 2020: Arunaloke Chakrabarti - Fungal rhinosinusitis
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Around 0.11% of the population in India suffers from chronic fungal rhinosinusitis. It is particular common during winter months when wheat threshing takes place and Aspergillus spore count is high. This talk describes the current classification system for different types of fungal rhinosinusitis, including risk factors, causative fungi, clinical presentation and treatment. Talk delivered at th...
AAAM2020: Teresa Zelante PhD - Tryptophan metabolism in fungal infections
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Indole is an ‘archetypical hormone’ derived from tryptophan metabolism that regulates the interaction of microbes and their plant or animal hosts. Aspergillus fumigatus produces an indole alkaloid (3-IAld) that binds the xenobiotic receptor and promotes IL-22 production, which modulates host resistance to invading fungi. Talk delivered at the 9th Advances Against Aspergillosis and Mucormycosis ...
AAAM2020: Bill Guyer - Gilead Research Scholars Program: Antifungals
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This program allows independent researchers to study areas of unmet need for the therapy areas covered by Gilead. The antifungals section offers junior researchers support of up to $130,000 over two years, and is divided into three areas: fungal biology; medical mycology; basic, clinical and translational research related to fungal diseases. Advances Against Aspergillosis 2020 Lugano, Switzerland
AAAM2020: David Andes - Aspergillus Breakpoints (CLSI)
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CLSI recently set susceptibility breakpoints for voriconazole against Aspergillus fumigatus, based on data including MIC distributions, PK/PD studies and clinical outcomes in various trials. MICs ≥2 μg/ml are linked to treatment failure Advances Against Aspergillosis and Mucormycosis 2020, Lugano, Switzerland.
AAAM2020: Hubertus Haas - Siderophores and Fungal Pathogenesis
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Advances Against Aspergillosis and Mucormycosis 2020, 27-29th February
AAAM2020: Yoshitsugu Miyazaki - Challenge for chronic pulmonary aspergillosis
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Long-term azole therapy is the mainstay of treating chronic pulmonary aspergillosis, but some patients harbour azole-resistant Aspergillus strains, which often carry CYP51A mutations. CRISPR-Cas9 genome editing was used to create strains with one or more mutations seen in clinical isolates to determine whether they were responsible for resistance, and then used molecular docking to show the mec...
AAAM2020: Jesus Guinea Ortega - CLSI/EUCAST: AFST for breakpoints - where are we going?
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Advances Against Aspergillosis and Mucormycosis 2020 27-29th February
AAAM2020: Andrew Bush - Kids, difficult asthma & fungus
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Paediatric SAFS (severe asthma with fungal sensitisation) is usually defined using the adult criteria, minus the IgE and IgG components. These children generally have more inflammation, driven by alarmin IL-33. Reducing mould exposure in the home and from contaminated nebulisers is crucial. Anecdotally some benefit from antifungals, but clinical research is needed. Advances Against Aspergillosi...
National Aspergillosis Centre Specialist Physio Mairead Hughes talks to ABPA patient Barbara
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Mairead talks to ABPA patient Barbara about the benefits she found to her health from using a PEP airways clearance device. The aim of physiotherapy for chest clearance is to remove the excess secretions which are produced by the lungs in response to infection, virus or toxins from fungal stimulus. Regular maintenance treatment is important to keep a clear chest and reduce the need for repeated...
Diagnosis and treatment of chronic pulmonary aspergillosis
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This talk was delivered by Professor David Denning to Ghana on February 1st 2019, World Aspergillosis Day.
World Aspergillosis Day by The Aspergillosis Trust
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The Aspergillosis Trust www.aspergillosistrust.org are helping promote World Aspergillosis Day 2019, on Feb 1st every year
Sporotrichosis by Prof Alexandro Bonifaz, Hospital General de Mexico
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Sporotrichosis by Prof Alexandro Bonifaz, Hospital General de Mexico
Aspergillosis Community at NAC November 2018
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Aspergillosis Community at NAC November 2018
Aspergillosis Community at NAC August 2018
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Aspergillosis Community at NAC August 2018
Leslee talks about her experiences with Aspergillosis
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Leslee talks about her experiences with Aspergillosis
Aspergillosis Community at NAC July 2018
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Aspergillosis Community at NAC July 2018
Aspergillosis Community at NAC May 2018
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Aspergillosis Community at NAC May 2018
Medical Mycology Worldwide - Making it possible for all MM Groups to have a web
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Medical Mycology Worldwide - Making it possible for all MM Groups to have a web
Aspergillosis Community at NAC March 2018
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Aspergillosis Community at NAC March 2018
Graham 8th Advances Against Aspergillosis Patients Support Resources
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Graham 8th Advances Against Aspergillosis Patients Support Resources
Aspergillosis Community at NAC December 2017
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Aspergillosis Community at NAC December 2017
Aspergillosis Community at NAC November 2017
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Aspergillosis Community at NAC November 2017
Aspergillosis Community at NAC October 2017
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Aspergillosis Community at NAC October 2017
You probably need to get rid of your houseplants 😢 it made a big difference for me
I have this dammit!😖😭 been spitting blood for 6 months on all kinds of MEDs not working they want to do surgery! 6 to 8 hour shit! am 60 years old and built like a rock now am skinny losing weight and muscle mass been thro hell spitting every min I must have spit out 2 gallons of crap Black,Brown,Yellow,Green mucus and blood and blood clots throat is swollen my thyroid is dead dam MOLD spore 😡🤬😠 I almost died in 2014 from Liver Cirrhosis Hep C stage 3 . Germany
I am dying of COPD, extreme asthma and ABPA but my respiratory consultant seems to know nothing about it and will not help me and keeps telling others there is nothing wrong with me despite 12 ambulance call outs and 2 a&e admissions and a CT scan with spots on my lungs in the last 6 months. Every morning I scrape fungus out of my mouth. I am dying but my respiratory consultant Dr Kamarth cares not a jot- I would be better helped in Africa which says it all about the state of the NHS in the UK...
I have been diagnosed with ABPA but my respiratory consultant at my NHS hospital will not help me and its like he doesn't know what I have- the NHS are negligent and I am dying and nobody cares- I wish I was an immigrant as somebody may care about me in the NHS.
I have ABPA but my respiratory consultant doesn't care and will not help me- I have had 12 ambulance call outs and 2 A&E admissions with my CT scan showing spots on the lungs but, unlike Jacqueline, nobody gives a sh... The NHS are a joke.
Is there any chance of cure for a healthy 40’s male non smoker healthy immune system and no lung problems besides chronic pulmonary aspergillosis???
Is there hope of a cure? I was just prescribed Intraconozole and from what I understand it has 50/50 cure rate. I believe I was infected for 3 years so mine is classified as chronic. Prior I went to 3 doctors about it and all blew me off.
Can I ask you what that last medication was. I am just starting this journey. Also is there hope of a cure?
After struggling with Aspergillus Sinusitis, my uncle found remarkable relief through IAFA Ayurveda’s natural solutions. Within just 3 months, his symptoms significantly improved. Their holistic approach truly made a difference. We are grateful for their effective and compassionate care.
This guy is a master on his discipline
I'm taking a spoon of coconut oil plus a candida supplement, here's hoping...
What is the dosage if using potassium iodide? both concentration and amounts? thank you
This is impossible
Am ascultat povestea ta. Sunt bolnava de aspergiloza de 8 ani, sunt operata la plămân de 2 ori. Simptome similare am avut si eu. M-am simțit foarte rău mai mulți ani, acum sunt mai bine. E interesant sa împărtășești suferința cu cei ca tine. Dumnezeu sa ne dea sănătate la toți si viața lunga.
God bless you ❤ I’ll pray for your healing
Watching this because I will have my sputum collection tomorrow.
Same I have been trying since midnight 😂
can relate to this so much, thank you
What meds are you taking if you do not mind me asking as i suffer from ABPA as well
Continue to have frequent Chest Infection’s. I reacted badly to Itraconazole with Severe Hypertension & Liver Function deterioration. Just had IgG serum antibodies taken- 146mg/ml. What are my option’s.
It helped! Thank you
I cannot understand her. At all. Her English is terrible.
It didnt do much for me!.
What antifungal therapy is she getting, she doesn’t say what is working for her?
super helpful! thank you. Wish me luck tomorrow :D
Excellent lecture
My mother got this and we were surprised as to how fast it spread from a severe headache to bulging of her eye to losing her eye in a matter of day. It was a relatively early diagnosis and treatment started with amphoterrible that really had severe side effects with no stop in progression of the disease. Voriconazole also didn't help. It kept spreading until she got hydrocephalus and was in a state of semi consciousness. Eventually we started on itraconazole and alternative treatments and continued for a couple of years with VP shunt installed to get ber consciousness back. She has recovered although bad ridden with multiple nerve issues particularly affecting her speech. She is a centre of our world and it really turned upside down after the disease. But as a family you have to keep fighting and outcome will be in your favour.
How can you realize that you have something like that in your body?
The best thing I did to improve my quality of life was megadose vitamin D (with vitamin k2 and magnesium) this rocketed my energy levels and drastically improved my immune system resulting in far fewer chest infections.
I surfing ABPA aspergillosis
Please help Everyone save me pls tell me any treatment pls😭😭😭😭😭😭😭😭😭😭😭
I’m on voriconazole 200 mg twice day for 9 months now.
@theroses9201 are you cured?
Identified a patient with chronic pulmonary aspergillosis with chest ulcers in uganda kitgum
Where did you get treatment please...
Impresionante q tuvieras eso! Q maravilla q lo quitaron!
Hmm, maybe Robert Downey, Jr. is describing the above video? ua-cam.com/video/hGLxY9xRQj8/v-deo.html
Is there a possibility that this cannot be detected on a chest CT? I’ve been told that I have some benign nodules, some airway thickening and a lot of inflammation. Other than that they can’t tell me anything, other than get another chest CT in 3-6 months…. Great, what am I supposed to do about this horrible, chronic cough all day every day?! No help whatsoever! 🤬 I have to take Delta 8 CBD just to ease some of the coughing, which doesn’t take it away completely. I also take a bedtime Delta 8 so that I can at least sleep at night. I have heard that anti fungals really don’t do anything for Aspergillosis. I will be talking to my Naturopath next week to have him test my sputum and if I have Aspergillosis I’m going to find out what he thinks is the best option for treatment. I cannot believe with as advanced as we are and all the “medical advances” that we can’t find real relief and healing from this! Blows my mind!
Aspergillosis is only treated with antifungals..... It's a fungal disease. It may not show up on CT but can be better detected through sputum samples or biopsy during bronchoscopy. What kind of symptoms are you having?
Thanks a lot, helped me out. Got away from Budesonid during my Itraconazole treatment and do much better now. It feels like my Immunsystem got back and is fighting the Aspergillosis. Thanks!
Sir hindi mai bnao video
My brother was recently diagnosed with this, but he is not responding well to the treatment. It seems that this fungus is very strong.
I have been diagnose with pulmonary aspergillosis since 2021 . Can you lend me a help so i can become normal again .
will certainly be taking this information to my sputum test tomorrow. thank you
Truth is we’re all in trouble of aspergillosis and the new water molds like pythium Insidious ( fungus like but not true fungus) me and my girl do sick no help at all. Most drs don’t understand black mold in homes can be deadly. This dr is so nice wish I new him.
The current guidelines of not testing until it's too late, and even then not treating until there is organ damage are criminal and destroy countless lives. All those doctors who are completely incapable of listening and thinking with their own head will burn in hell. Don't fool yourselves, you actively make the choice to kill people or condemn them to a lifetime of misery, it's 100^% on you.
Absolutely agree and couldn’t have said it better myself! The ONLY help I’ve gotten is from Naturopathic Dr’s or Functional Medicine. I believe they will burn in Hell for it too, all about the money and in bed with big pharma! It’s sickening! 🤬 We really have to take our health into our own hands!
So what did we learn in 52 seconds? That we can't learn anything in 52 seconds.
What’s the trial drug called? My mother is currently battling MAC lung disease and Aspergillosis. She’s Currently taking voriconazole 😢
very informative, thank you Rami Irani Amman Jordan
This is a brilliant account of ABPA. Very accurate. Thank you x
That must smell 10x worse than 💩 🤮
I have abpa since childhood I'm age 35 please any solution I am very problem please any contact number
👍👍👍🤕🤕🤕
Im scared i have this, whats the first thing you do t find out
So you need to get a chest x ray, and the doc will look at your clinical symptoms your medical history(if you have asthma or cystic fibrosis) and check for mucus plugging in the airways. It's pretty rare so the symptoms can overlap with other conditions like tb or bronchiectasis. Also a bronchoscopy and sputum culture would help.(brown sputum is a telltale sign btw)
@@afrozahossian5345are you abpa patient??