The University of Southern Indiana Theatre puts on four mainstage productions annually, with USI performing arts students acting as actors, designers, and technicians. The USI Theatre season is designed to introduce students to a wide range of theatre styles, from musical to drama, contemporary to classic. Once a year, students have the opportunity to act alongside professional union actors in the Repertory Project, providing mentorship and bringing a professional attitude into the collegiate training.

The program emphasizes a well rounded education with hands on experience both on and off stage. Student designers are provided opportunities to design on the main Performance Center stage as well as the student focuses Mallette Theatre black box space.