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Jehad Yasin
Приєднався 10 лис 2017
Jehad Yasin
Medical student at The University of Jordan.
Interested in Biostatistics, Bioinformatics, and Systems Biology.
Medical student at The University of Jordan.
Interested in Biostatistics, Bioinformatics, and Systems Biology.
A Primer to Molecular Docking Using AutoDock (Part 1, Theory)
Types of Molecular Docking Scoring Functions
1. Empirical Scoring Functions
• Based on experimental binding data.
• Includes van der Waals, hydrogen bonding, desolvation, and entropy terms.
• Examples: ChemScore, GlideScore.
2. Knowledge-Based Scoring Functions
• Derived from statistical analyses of known protein-ligand complexes.
• Uses interaction frequencies from structural databases.
• Examples: PMF (Potential of Mean Force), DrugScore.
3. Physics-Based Scoring Functions
• Uses molecular mechanics force fields (e.g., electrostatics, van der Waals).
• Accounts for dynamic molecular behavior (molecular dynamics simulations).
• Examples: CHARMM, AMBER, GROMACS.
4. Consensus Scoring
• Combines multiple scoring functions for improved accuracy.
• Reduces bias of individual methods.
• Example: Integration of empirical, physics-based, and knowledge-based scores.
1. Empirical Scoring Functions
• Based on experimental binding data.
• Includes van der Waals, hydrogen bonding, desolvation, and entropy terms.
• Examples: ChemScore, GlideScore.
2. Knowledge-Based Scoring Functions
• Derived from statistical analyses of known protein-ligand complexes.
• Uses interaction frequencies from structural databases.
• Examples: PMF (Potential of Mean Force), DrugScore.
3. Physics-Based Scoring Functions
• Uses molecular mechanics force fields (e.g., electrostatics, van der Waals).
• Accounts for dynamic molecular behavior (molecular dynamics simulations).
• Examples: CHARMM, AMBER, GROMACS.
4. Consensus Scoring
• Combines multiple scoring functions for improved accuracy.
• Reduces bias of individual methods.
• Example: Integration of empirical, physics-based, and knowledge-based scores.
Переглядів: 130
Відео
Trial Sequential Analysis: Is Your Meta-Analysis Reliable? (English/Arabic)
Переглядів 2573 місяці тому
TSA PROGRAM: drive.google.com/file/d/1T7nhzNKkBKJbvTq0VXPpuwvMb523kzPP
Introduction to Network Meta-Analysis on R (Arabic/English)
Переглядів 1537 місяців тому
Introduction to Network Meta-Analysis (R Language) Applied example on Randomized Clinical Trials
Open Data Research: Multi-Omics in Cancer Genomics (Arabic/English)
Переглядів 2349 місяців тому
Edis/Clarifications: [18:47] DNA Sequening for Genome-Level assembly relies on DNA reads, not RNA. However, NGS for RNA-Seq relies on RNA reads/fragments (that are reverse-transcribed to cDNA). “Next-generation sequencing (NGS) is a new technology used for DNA and RNA sequencing and variant/mutation detection.” [38:45] Quantification algorithm takes annotation file (like GTF) and the BAM (align...
Predictive AI in Medical Research: Applied Walkthrough | الذكاء الاصطناعي في البحث الطبي
Переглядів 215Рік тому
Speakers: - Jehad Yasin - Mohammad Ghanem The University of Jordan, Amman, Jordan #ai #medicine #ml #research
Introduction to Data Analysis in Epidemiological and Survey-based Research | تحليل البيانات البحثية
Переглядів 393Рік тому
Theoretical introduction to basic concepts in data analysis. Introduction to a wide variety of basic concepts in biostatastics and data analysis techniques utilized in research. Part II (Practical Session) will be uploaded. Topics: - What is Data Analysis? - Where and How? - Some Examples - Mean and Proportion Differences - Correlations - Parametric and Non-parametric Statistics - Normality Tes...
Essentials of Research Workshop | أساسيات البحث العلمي
Переглядів 454Рік тому
Presenters: - Leen A. Kuttob - Jehad A. Yasin Language: Arabic English Slides: drive.google.com/file/d/1dpJ4piGc-_SMcRGE8WM7O9h-jPlBQigI/view?usp=drivesdk The University of Jordan All rights reserved.
Bulk RNA-Seq Worshop (2)
Переглядів 1462 роки тому
Bulk RNA-Sequencing Analysis using R Start of the meeting: 00:50 You can skip the minutes 25:00 - 33:00. During this time, the instructor faced a technical issue. Google Drive Materials: drive.google.com/drive/folders/1 JysoqYdDeyf4EaLsjDmYthaaAKL6zL Social Media and Links: linktr.ee/joscience All copyrights reserved.
Mitochondrial Dysfunction and Type II Diabetes: OXPHOS Decoupling and Impairement of Insulin Release
Переглядів 2322 роки тому
The video discusses how mitochondrial defects including Oxidative Phosphorylation Decoupling can lead to Diabetes Type II. In this video, we will discuss how insulin release is impaired by specific mitochondrial dysfunctions. Part 2 will be uploaded soon and it will be discussing how the body can develop insulin resistance as a result of specific mitochondrial defects. Link to presentation: dri...
Single-Cell RNA-Seq Data Analysis: Part 1 (Theory)
Переглядів 1422 роки тому
A comprehensive review over Single-Cell RNA-Seq Data Analysis. This part (Part 1) of the video discusses the theoretical section of RNA-Seq and scRNA-Seq. Part 2 covers the programming section. Start: 03:13 Clarification: Normalization takes into account the length of genes in kilobases. Genes with greater lengths tend to have more reads mapped to them during the computerized mapping process, w...
ADH (Vasopressin): Mechanism of Action
Переглядів 1682 роки тому
The following video discusses how ADH works. The video explains physiological, anatomical, histological, and pathological aspects related to ADH (Vasopressin) Slides: drive.google.com/file/d/1-6xJVUO174W7YM0X_VkhpDhYCCegT8Td/view?usp=sharing Tutor: Jehad Yasin Location: Amman, Jordan Note: ADH is released by the pituitary gland. The stimulation of ADH secretion is done by the hypothalamus. Cont...
Codeavour 2021 Project - HydroSmart - Plant in Water to Save Water
Переглядів 1,3 тис.2 роки тому
Codeavour 2021 Project, HydroSmart Prize: Sunfounder Best Hardware Project across 68000 teams, Codeavour 2021 Automated Hydroponic Planting System which involves AI implementation and the utilization of both hardware and software. Pictoblox was mainly used to make the project along with other extensions linking to social media and emails. Supervised Machine Learning Model was used for plant-ima...
How can I join this workshop?
The workshops is over. Practical session will be uploaded soon on my channel.
00:30 ممكن أعرف أين محاضره ال. Meta regression.. الله يكرمك
@@DrAhmed-or9rf مرحبا محاضرة زميلي أسامة يونس: ua-cam.com/video/wg9nUkSQZBY/v-deo.htmlfeature=shared
it was a nice and very good lecture sir. If you kindly enough, could you do the meta-diagnosis video lecture sir? Thank you sir, may god bless you always
Please talk slower
Please translate into the English language. Thank you
TSA link for download is not working
Check the description. I have attached a drive link for the compressed folder.
شكرا جدا ..اول شرح عربي للموضوع فى يوتيوب
العفو
موفق دكتور جهاد الله يحميك
Interesting!
موفق حبيبي جهاد
Amazing !!!
good job
Please please upload part 2 - insulin resistance.
Excellent!!!!! Thank you so much Dear ❤️ It was really really helpful. May Allah bless you. Eagerly waiting for part 2.
Thank you Jehad
Thank you Mr. Jehad
Finally found someone who can explain physiology the right way!