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Inside Exercise
Australia
Приєднався 15 чер 2022
Inside Exercise brings to you the absolute who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics.
Twitter: @inside_exercise @GlennMcConell1
Email: glenn.mcconell@gmail.com
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics.
Twitter: @inside_exercise @GlennMcConell1
Email: glenn.mcconell@gmail.com
#88 - Exercise preserves muscle and metabolism during cancer with Dr Lykke Sylow
Dr Glenn McConell chats with Associate Professor Lykke Sylow from The University of Copenhagen. She is a rising star in exercise metabolism and in particular the effect of exercise on cancer. This is the second podcast episode on exercise and cancer (See Professor Kathryn Schmitz episode #9).
Remarkably she said that if you are a non-smoker your biggest risk of getting cancer is inactivity. Not clear if this is independent of obesity etc. Can associated with a reduction of insulin sensitivity and also cachexia (with the loss of muscle mass is very important). The cancer itself may cause insulin resistance. Exercise can reduce the likelihood of getting cancer, improve the prognosis during cancer treatment and reduce the likely of getting cancer again. There is even evidence that exercise can improve the effectiveness of chemotherapy and reduce the extent of metastasis. Really remarkable stuff. A lot more research is needed to clarify these things. X: @lykkesylow
0:00. Introduction
2:40. Lykke is a rising star
3:59. Cancer and exercise overview
6:09. Wasting of muscle mass with cancer
7:00. Evidence that exercise reduces the risk of getting cancer
11:40. Inactivity / obesity and cancer
13:03. Glucose metabolism and cancer
15:20. Cancer cachexia
19:05. The cancer itself may cause insulin resistance
22:55. Cancer cachexia/ loss of muscle mass
29:30. When loss weight tend to lose muscle
30:30. Mechanisms of cancer cachexia
33:20. Pre cancer muscle mass/strength and survival
35:50. With cancer insulin resistance may come before cachexia
40:07. What do different cancers have different effects?
41:48. Exercise can improve tolerance to cancer treatment/fatigue
46:20. Does exercise reverse the insulin sensitivity with cancer
46:30. Exercise increases muscle glucose use during and after exercise
52:10. Exercise during chemotherapy treatment
54:55. What kind/type of exercise are we talking about?
1:01:20. Mechanisms/AMPK
1:03:25. Exercise reduces fatigue in cancer
1:04:13. Exercise may improve the effectiveness of chemotherapy
1:06:25. Exercise may reduce metastasis of cancer
1:08:30. Sex differences, cancer and exercise
1:12:20. Age, cancer and exercise
1:15:15. Availability of exercise in oncology departments
1:18:50. Diet vs exercise in cancer treatment
1:19:50. Strength vs endurance training with cancer
1:21:22. Takeaway messages
1:26:23. Outro
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: glenn.mcconell@gmail.com
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
UA-cam: www.youtube.com/@insideexercise
Anchor: anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: anchor.fm/insideexercise
Podcast Addict: podcastaddict.com/podcast/4025218
Not medical advice
Remarkably she said that if you are a non-smoker your biggest risk of getting cancer is inactivity. Not clear if this is independent of obesity etc. Can associated with a reduction of insulin sensitivity and also cachexia (with the loss of muscle mass is very important). The cancer itself may cause insulin resistance. Exercise can reduce the likelihood of getting cancer, improve the prognosis during cancer treatment and reduce the likely of getting cancer again. There is even evidence that exercise can improve the effectiveness of chemotherapy and reduce the extent of metastasis. Really remarkable stuff. A lot more research is needed to clarify these things. X: @lykkesylow
0:00. Introduction
2:40. Lykke is a rising star
3:59. Cancer and exercise overview
6:09. Wasting of muscle mass with cancer
7:00. Evidence that exercise reduces the risk of getting cancer
11:40. Inactivity / obesity and cancer
13:03. Glucose metabolism and cancer
15:20. Cancer cachexia
19:05. The cancer itself may cause insulin resistance
22:55. Cancer cachexia/ loss of muscle mass
29:30. When loss weight tend to lose muscle
30:30. Mechanisms of cancer cachexia
33:20. Pre cancer muscle mass/strength and survival
35:50. With cancer insulin resistance may come before cachexia
40:07. What do different cancers have different effects?
41:48. Exercise can improve tolerance to cancer treatment/fatigue
46:20. Does exercise reverse the insulin sensitivity with cancer
46:30. Exercise increases muscle glucose use during and after exercise
52:10. Exercise during chemotherapy treatment
54:55. What kind/type of exercise are we talking about?
1:01:20. Mechanisms/AMPK
1:03:25. Exercise reduces fatigue in cancer
1:04:13. Exercise may improve the effectiveness of chemotherapy
1:06:25. Exercise may reduce metastasis of cancer
1:08:30. Sex differences, cancer and exercise
1:12:20. Age, cancer and exercise
1:15:15. Availability of exercise in oncology departments
1:18:50. Diet vs exercise in cancer treatment
1:19:50. Strength vs endurance training with cancer
1:21:22. Takeaway messages
1:26:23. Outro
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (link.springer.com/book/10.1007/978-3-030-94305-9).
Connect with Inside Exercise and Glenn McConell at:
Twitter: @Inside_exercise and @GlennMcConell1
Instagram: insideexercise
Facebook: Glenn McConell
LinkedIn: Glenn McConell www.linkedin.com/in/glenn-mcconell-83475460
ResearchGate: Glenn McConell
Email: glenn.mcconell@gmail.com
Subscribe to Inside exercise:
Spotify: shorturl.at/tyGHL
Apple Podcasts: shorturl.at/oFQRU
UA-cam: www.youtube.com/@insideexercise
Anchor: anchor.fm/insideexercise
Google Podcasts: shorturl.at/bfhHI
Anchor: anchor.fm/insideexercise
Podcast Addict: podcastaddict.com/podcast/4025218
Not medical advice
Переглядів: 701
Відео
#87 - Exercise and sports cardiology with Professor Paul D. Thompson
Переглядів 1,5 тис.4 місяці тому
Dr Glenn McConell chats with Professor Paul D. Thompson who is Chief of Cardiology, Emeritus at Hartford Hospital, Hartford, CT and Professor of Medicine, Emeritus at the University of Connecticut. He has published over 500 peer reviewed journal articles, was a past President of the American College of sports medicine (ACSM) and was a impressively fast marathon runner. This is the third of a se...
#86 - Can changing gait reduce running injuries with Dr Bryan Heiderscheit
Переглядів 7265 місяців тому
Dr Glenn McConell chats with Professor Bryan Heiderscheit from the University of Wisconsin in USA. He is an expert on running injuries. This is the third of a series of podcast episodes on running injuries (See Professor Irene Davis’s and Associate Professor Rasmus Østergaard Nielsen’s episodes). Bryan focuses on overstriding and how increasing the stride rate can reduce overstriding and theref...
#85- Training load and running-related injuries with Dr Rasmus Østergaard Nielsen
Переглядів 9277 місяців тому
Dr Glenn McConell chats with Associate Professor Rasmus Østergaard Nielsen from Aarhus University who is an expert on the affect of training load and shoes on running-related injuries. This is the second of a series of podcast episodes on running injuries (See Prof Irene Davis’s episode). Rasmus went from an overweight gamer to an injured runner to a exercise researcher! His research focuses on...
#84 - Effect of shoes and gait on running injuries with Professor Irene Davis
Переглядів 8898 місяців тому
Dr Glenn McConell chats with Professor Irene Davis from the University of South Florida who is a top running injuries researcher and the current president of the American College of Sports Medicine. She makes the argument that we were born to run and have evolved to land on the ball of the foot during running and this reduces impact load compared with landing on the heel. Modern running shoes t...
#83 - Applying Sport Science: Lessons learnt from the Olympics and the NBA with Dr David Martin
Переглядів 9248 місяців тому
Dr Glenn McConell chats with Dr David Martin. David has a remarkable and varied background starting off as a research scientist at the Australian Institute Sport and then National Sports Science Coordinator at Cycling Australia. He then became Director, Performance Research and Development at the Philadelphia 76ers. He is currently Chief Scientist, Director of Performance at Apeiron Life, San F...
#82- Heart transplant Ironmen!: Upper limits of performance post HT. Prof Mark H, Dwight K + Elmar S
Переглядів 4939 місяців тому
Dr Glenn McConell chats with Professor Mark Haykowsky from the University of Alberta, Canada and remarkable heart transplant recipients Dwight Kroening, Edmonton, Alberta and Elmar Sprink, Cologne, Germany. Dwight was very fit before a heart defect resulted in his heart transplantation (HT) way back in 1986. Despite being at deaths door he was sceptical of HT. They didn’t want him to exercise a...
#81 - Muscle recovery after joint injury with Dr Chris Fry
Переглядів 50510 місяців тому
Dr Glenn McConell chats with Associate Professor Chris Fry from the University of Kentucky, USA. Joint injury causes muscle weakness and atrophy (reductions in muscle size) due to the the inactivity but also separately due to the injury itself. Substances are released from muscle to help repair the joint/bone. Prehab is important before surgery. There can be residual effects long after joint in...
#80 - Epigenetics of exercise adaptation and "muscle memory" with Dr Kevin Murach
Переглядів 1,4 тис.10 місяців тому
Dr Glenn McConell chats with Assistant Professor Kevin Murach who is a rising star from the University of Arkansas, USA. Kevin is an expert on muscle, muscle growth, adaptation to exercise training, “muscle memory”, the regulation of muscle growth and muscle memory and the effect of aging etc. Muscle memory definitely seems real (especially in slow muscle fibers). Looks like epigenetics involve...
#79 - Exercise and the brain with Dr Jill Barnes
Переглядів 1,9 тис.11 місяців тому
Dr Glenn McConell chats with Associate Professor from the University of Wisconsin-Madison, USA. Jill is an expert on the brain and exercise. We discussed the effect of acute (one bout) and chronic physical activity/ exercise on cognitive function, brain blood flow (BBF), dementia/Alzheimer’s disease risk and progression etc. A very interesting chat. Twitter: @Barnes_Lab 0:00. Introduction and w...
#78 - Glucose spikes are normal physiology!!! Drs Nicola Guess and Jonathan Little
Переглядів 4,8 тис.Рік тому
Dr Glenn McConell chats with Dr Nicola Guess from Oxford University, England and Professor Jonathan Little from the University of British Columbia, Canada. Nicola is a dietitian researcher with many years of expertise including the importance or otherwise of glucose “spikes” or excursions and the pros and cons of continuous glucose monitor use. Jonathan is an expert on exercise metabolism who i...
#77 - Exercise and pregnancy with Professor Margie Davenport
Переглядів 432Рік тому
Dr Glenn McConell chats with Professor Margie Davenport from the University of Alberta, Canada. She is an expert on exercise and pregnancy. We discussed the effect of pregnancy on the health (including pre-eclampsia and gestational diabetes) and exercise performance of the mother and on the health of the fetus during pregnancy and the offspring after pregnancy. It became very clear that there n...
#76 - Creatine in exercise and health with Professor Darren Candow
Переглядів 2,1 тис.Рік тому
Dr Glenn McConell chats with Professor Darren Candow from the University of Regina. Saskatchewan, Canada. He is an expert on creatine (Cr) and the effects of creatine supplementation on resistance exercise and other exercise. He is also examining the role of creatine in bone metabolism and cognitive function. Get greater increases in strength than muscle mass when supplement with Cr during resi...
#75 - Exercise in extreme environments: sex as a biological variable with Dr Nisha Charkoudian
Переглядів 574Рік тому
Dr Glenn McConell chats with Associate Professor Nisha Charkoudian from the US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA. She is an expert on the effects of extreme environments on exercise capacity. We talked about dehydration, electrolytes, effects of humid vs dry environments etc. We also discussed the importance of considering sex as a biological variable...
#74- Are beta2-agonists just asthma treatments or also performance enhancers? With Dr Morten Hostrup
Переглядів 749Рік тому
#74- Are beta2-agonists just asthma treatments or also performance enhancers? With Dr Morten Hostrup
#73. Protein and muscle adaptations to loading and unloading with Professor Luc van Loon
Переглядів 3,7 тис.Рік тому
#73. Protein and muscle adaptations to loading and unloading with Professor Luc van Loon
#72 - Tendons: from exercise adaptation to injury and rehabilitation, with Professor Michael Kjær
Переглядів 2,1 тис.Рік тому
#72 - Tendons: from exercise adaptation to injury and rehabilitation, with Professor Michael Kjær
#71 - Aging, inactivity, atrophy and exercise with Professor Sue Bodine
Переглядів 2,5 тис.Рік тому
#71 - Aging, inactivity, atrophy and exercise with Professor Sue Bodine
#70 - Sleep, recovery and fatigue in athletes with Professor Shona Halson
Переглядів 1,9 тис.Рік тому
#70 - Sleep, recovery and fatigue in athletes with Professor Shona Halson
#69 - The heart and exercise: Should middle-aged men pull on lycra? With Dr Andre La Gerche
Переглядів 4,2 тис.Рік тому
#69 - The heart and exercise: Should middle-aged men pull on lycra? With Dr Andre La Gerche
#68 - Muscle fiber types revisited with Professor Wim Derave
Переглядів 2,2 тис.Рік тому
#68 - Muscle fiber types revisited with Professor Wim Derave
#67 - Limitations to VO2 max with Professor Jose Calbet
Переглядів 3 тис.Рік тому
#67 - Limitations to VO2 max with Professor Jose Calbet
#66 - Exercise and the cardiovascular system with Professor Ylva Hellsten
Переглядів 1,4 тис.Рік тому
#66 - Exercise and the cardiovascular system with Professor Ylva Hellsten
What regulates glucose uptake during exercise? Is it really AMPK??
Переглядів 382Рік тому
What regulates glucose uptake during exercise? Is it really AMPK??
#65 - Interactions between exercise and insulin with Professor Erik Richter.
Переглядів 1,3 тис.Рік тому
#65 - Interactions between exercise and insulin with Professor Erik Richter.
#64 - Blood flow restriction and exercise with Professor Jeremy Loenneke
Переглядів 1,7 тис.Рік тому
#64 - Blood flow restriction and exercise with Professor Jeremy Loenneke
#63 - Adipose tissue adaptations to exercise and exercise and antipsychotics. Professor David Wright
Переглядів 968Рік тому
#63 - Adipose tissue adaptations to exercise and exercise and antipsychotics. Professor David Wright
#62. Interaction of exercise with muscle circadian clocks with Professor Karyn Esser
Переглядів 1,2 тис.Рік тому
#62. Interaction of exercise with muscle circadian clocks with Professor Karyn Esser
#61 - Volume versus intensity with Dr David Bishop
Переглядів 9 тис.Рік тому
#61 - Volume versus intensity with Dr David Bishop
#60 - Skeletal muscle aging and mitochondria: thinking beyond the powerhouse with Dr Russell Hepple
Переглядів 1,3 тис.Рік тому
#60 - Skeletal muscle aging and mitochondria: thinking beyond the powerhouse with Dr Russell Hepple
When are you gonna address your mates redacted studies? Come on now, where’s the integrity of your so called “reputable people”. Go address their bs
@@jacklauren9359 What redacted studies? Not aware of them. Please advise.
Great interview. Rather than focus on shoes would seem better to look more at differences in attributes of people wearing them? East African runners who are slim, have grown up not wearing shoes and running a lot can run fast and injury free wearing any sort of footwear. Up until the 1970s running boom the few athletes who ran in developed countries were not dissimilar. Watch any community running event today and other than runners towards the front most will be very different, not only in form but also in how they move. Many will also think a lot about what they are wearing on their feet when assessing performance. For me in my return to running there have not been any magic shoes. When I have injured myself it has always been because of impatience, running too fast too soon without allowing sufficient time for my body to adapt to extra load. I used to suffer greatly from archilles and calf injuries and thought I was a natural forefoot runner but after watching my feet turn out as I walked concluded I had just lost range of motion, in my big toes , ankles and hips. After restoring lost range of motion I now can land mid foot, better balance load and run largely injury free. Currently working on further improving hip extension to move my stride more to the rear and centre of mass forward. Believe running is just another form of movement. Movement patterns can change for better or worse over time. Martial arts demonstrate well how improved movement patterns can best be learned at first slowly, then speed and power will come. Why should running be any different? My running cue on each stride that works well for me is glutes, extend, lift. If you compare the running mechanics of better runners to the rest you will likely see why
These people are anti low carb??
Can’t believe they are talking about cholesterol
Why don’t you have Tim Noakes on??
Do not understand why distance is used as a training measure rather than time of run. An elite runner can cover 5k in around 15 minutes or less, while most recreational runners would need to be able to sustain a running effort of 30 minutes or more to travel the same distance. I like the low speed heart rate training methods because not only do they build endurance and strengthen tissues but also lower injury risk . Distance traveled is less important than duration of effort. Although what is amazing is how distance covered increases due to faster running speed as fitness and running efficiency improve. Speed training for me is problematic from an injury standpoint. In events 5k and longer being able to sustain effort pays off better than being able to run very fast anyway? Although the 30 20 10 approach to interval training worked well for me with sprints at about 90 percent maximum. Ran A hilly 10k trail run without problems a few months back. Leads me to think knee injuries are more due to poor running biomechanics than distance run. Perhaps heel strikers do not understand and fully appreciate the essential differences between walking and running strides? Forefoot running may be Ok for fast elite middle distance runners in events lasting four minutes or less but for recreational runners running in endurance events of 5k or longer I believe calves and archilles cannot take the repettive strain. Latest research shows that even elite runners favour a mid foot landing over those distances, while over a marathon most elites are heel strikers, particularly towards the end as they fatigue? Foot strike patterns, like ground contact times, stride lengths and cadence, are mostly a function of running speed over all distances? perhaps there are far fewer injuries amongst older runners because there are not only far fewer older people running, but also those prone to injury have quit?
Before the 1970s there was nothing published on recreational running injuries because there was no recreational running. I had some success as a high school runner in the early 1960s and can clearly remember competing in cross country races barefoot like all the other competitors. Only competitive runners ran. And they had runners bodies, not overweight couch potato bodies, which lack tissue strength and have insufficient range of motion to run with good biomechanics. So far as heel or forefoot striking is concered, everybody runs more on their heels at slow speeds and moves to forefoot if capable of running at higher speed? I changed to attempting a midfoot landing from forefoot and that has been good for me in reducing calf strains. What matters more is that at mid stance your foot is not too far forward of your centre of mass. Excellent point about glute activation, this has made a huge positive improvement to my running. Easy to concentrate on using glutes and achieving greater hip extension when running slow. About time people ignored commercial interests and stopped tallking about and focussing on shoes. The causes of running injuries and ways to prevent them lie elsewhere. Agree about orthotics. Was told my running was over 30 years ago and fitted with them but eventually threw them away. Now I run at least 5k every week, often more. I walk around the house in wide toe flat sole shoes and bare feet in warmer weather and also frequently in soft sand at the beach . For me in my recent return to running the key has been to sense how well my body is adapting as I progressively increase intensity, duration and frequency of traiining effort and temporarly backing off at the first sign of overload. From the very start I have worked at restoring adequate range of motion in toes, ankles and hips to permit good running form. I wear many different types of shoes and just select those comfortable and suitable for the surface on which I will be running. Still make mistakes and suffer minor calf strains occasionally but that is just part of running. Also turned 78 recently which probably also contributes. If all this sounds a little twisted and embittered it is because I was another casualty of the barefoot shoe craze of a decade or so ago.
I have heard a lot zone 2 videoes and one issue I synthesize from them (and my experience)is that zone 2 if done with not to many hours doesnt make us tired. Another principle is that consistensy is king, and that overtraining, illness and injuries are sabotaging consistensy. To improve there are three factors thats basic. 1. Frequensy. 2. Time and 3. Intensity. Zone 2 allows high frequensy (training many days a week) with minimal need for recoverytime while still beeing a reasonably stong workout. Zone 2 can be hold for a quite long time without getting wasted. There are some experts that advice training at high intensity once a week, up in zone 3 or 4 and maybe 5 (in a 5 zone model). To get full power in the hard day we need to have enough rest, which means restday or easy training one or two days before the high intensity day. Zone 2 , avoiding drifting up to zone 3 enables earlier full rested full power day, than if you had been going harder.
Does Herman's stuff amount to, the body adjusts more than we thought? And how long does it take? And how much adjustment - if I train for a marathon then stop doing anything how long does it take for my weight to adjust to being much less active?
Also the focus is on weight. The real interest is health, what does Herman's stuff mean for this?
Is it safe to assume that the point of compensation is individual?
Many thanks for pushing on the details on this Glenn
Study subjects…. All men? Mostly men? He never identifies the study subjects. What about male/female differences. All these studies lean heavily with male subjects.
So wait....if you're fit then you're more likely to have a heart attack with a higher calcium score? 🤔
@@mikepoznanski617 No. He said the opposite.
We can’t understand the numbers he’s saying because of his accent. The fitter you are the less likely you’ll have a heart attack even though your score is high.
@ Oh ok. I don’t hear an accent. LOL. Correct.
@@insideexerciseIf you’re from New York, you hear a big accent. Sounds Australian or from New Zealand to me.
@@ginadonza3549 Yep. He and I are from Australia. If you want to know more about the topic watch the whole episode. 👍
That's nuts about the bone density. I'll tell my brother in law to have his checked as he uses a ventolin regularly as well as the more long lasting one.
Is there a greater systemic affect if you do both arms and legs at same time???n maybe do full body workout, or a uphill sprint???? Thanks 4 sharing! 🧠💥💯💪🏽👍🏾
Due to dental surgery, the foods I could eat plus the general discomfort really limited my calorie intake. I wound up losing about 7 pounds in a month and then continued following the eating pattern. A year later, I've lost 17 pounds despite some plateaus. I think most people have no clue about how many calories there are in the food we eat. We need to remember that before the 1950s, most people in the USA consumed fewer calories - either due to poverty, limited access to a variety of ingredients, or due to the labor involved in preparing food. Since the 1950's pre-packaged for has become more and more plentiful - the food indestry needs consumers and push their products. I think we all suffer from food additction to one degree or another.
Golden channel for learning ❤
I'm wondering has there been new papers on ketones and performance since March 2023 when this interview was done? I follow some distance sport influencers who seem to be taking ketones pre-workout and I'd assume the claim would be it's for performance, not recovery. Interesting discussion anyway! I haven't really bothered with the diet wars so learning about keto and several of the nuances was informative.
Id like to know too, the claim is that it helps a lot with cognition, recovery and endurance when been taken everyday for a long period of time. I wonder if these ketones studies were done taking the duration of intake (1month +) into consideration.
Really informative discussion. Thank you!
For older athletes +55, sprint interval training is better long term endurance training. Good to 'run the engine hot' one or two times a week. Heart rate to max for short duration, less chance of developing problems like afib and cardiomyopathy, as we see in life-long endurance athletes. Seems like 95%+ of athletes 55+ are involved in endurance training rather than SIT ... which is actually quite different from HIIT. Probably because it's easier to run slow than fast, and takes less preparation.
I can't believe that training 2-3 times a week has no effect on your cardiovascular system. I usually trained 3 times a week and my form was definitely improving and my resting heart rate went as low as 45 pulses per minute. However these were quite intense training sessions - cycling for 2-3 hours, and often more on Sundays.
@@kantrzyn I thought Ben said that get cardiovascular adaptations if the exercise is above the intensity of a normal walk. What you describe would be expected to result in CV adaptations and the reduction in resting heart rate definitely backs this up.
Beautiful explanation of the 80/20 concept, from a 42yr old amateur who struggles to train 7-8h a week and has a hard time recovering, and has hit the wall so many times, especially after starting to have a power meter to push my ego forward on every ride. More and more convinced to use hr and ventilatory threshold for low intensity and leave the power for the intervals. Or just ride my bike, which was the way I've achieved the biggest vo2max I've ever had before. First day with power meter: 48ml/kg after 3months: 42, burnt out
I began running and gym at your age - exactly at 42 (now 52). I didn't know about danger of high intensity exercising and pushed myself for couple years every day so much that I was exhausted every evening. Now I enjoy it and run much more and lift much heavier weights just for fun.
It is difficult to back off the intensity when you're limited on time. I would do 1 medium intensity and 1 really hard session a week and the rest easy zone 2. Try to extend one of the zone 2 sessions to at least 2 hours. Concentrate more on diet and sleep and reducing stress.
Hi, one of your earlier episodes discussed bone density loss in professional endurance athletes under extended highintensity exercise conditions, due to release or scavenging of calcium into the blood from the skeleton to ensure the heart muscle has adequate access to calcium ions to keep functioning. An increased calcium concentration in the blood during high intensity exercise, in other words. In this brilliant episode, as well as Levine’s, we hear that this same population has a higher occurrence of arterial calcium deposit. From the blood, you’d think. Is there any evidence of these being related, or any evidence that arterial calcification levels change (decrease) during intense physical activity?
Really interesting guest! Keep up the great work, Glenn.
My experience is that training extensively in minimal shoes clearly gives me cues that really discourage over-striding, encourage forward lean, and reduce bounce. And I immediately switched to avoid landing on my heels. There are a host of other benefits to minimal shoes relating to foot health and comfort. My situation was that started running when I switched to minimal shoes, which is the perfect time. That way my tendons could adapt while I was gradually building up running load. It's harder for current runners to make that kind of transition and not do too much, too soon.
I really appreciate this entire series of podcasts. Particularly I've enjoyed this series on running injuries, since I've started running regularly for the last few years.
My 30 yrs of fell running suggest this is crap. Exercise definitely burns calories, for me at least. No amount of compensation elsewhere in the body will account for a 2hr run or 20+miles a week.
I wish you could have interviewed him when he was younger. Even at 1.25x speed this is tough to follow. Excellent interview either way. Great information here.
@1h15m Dr Thompson talks about walking and seems to say that walking 8000 steps a day at a fast pace is a good thing to do. It appears his 8000 steps per day does not include incidental walking, which for me is 4000 to 5000 steps per day. So, is the recommendation in addition to other walking?
@@peterz53 Good question. Having a listen over that section again Dr Thompson was making the point that around 8000 steps a day is beneficial to reduce your heart disease risk but doing more brisk walking is even more beneficial. So I think he was just putting the two together by saying do around 8000 steps per day and include some intensity to your walking. And based on what he said elsewhere in the podcast episode I’m sure he would recommend doing more than that as well.
On exercise and diabetes, it seems like combining dietary changes with exercise would be a lot more effective. Obviously, this will work only for a minority of motivated people.
$150 here in Tennessee
$100 in NY
Excelent!
Thanks!
@@denisegordon2430 Thank you for that!
So no info for people with hypertension?
Nothing happened to me when I over did it.
Listened partly with disappointment as true candidate to explain cardiovascular disease and low carb effect is for example dr. Ford Brewer - this would modify this discussion w Nicola Guess greatly (insert exclamation point). Generalist and YouTubist popular such as Attia is incorrect example - not an expert in the matter. Glucose spike and glucose plateau indeed are proxies for insulin baseline (read GCM).
It is so easy to believe some of those influencers, like Peter Attia mentioned by Nicola, once they use some sort of "study" to back up whatever point they make. Most of us don't know whether or not those studies are faulty, or exist at all. It is great to hear what really might be happening in the body from actual experts carrying out research and writing articles. Thanks Glenn!
I was listening on the podcast and was so wishing Dr Sylow had talked about which actual cancers were most positively affected by exercise when she was introducing her work. When she didn't, I wish you had asked her.... I was so curious and interested. Later on a few cancers got mentioned, but only in passing. Worldwide top 5 in order of number diagnosed (2022): lung (12.4%), female breast (11.6), colorectal (9.6) prostrate (7.3) and stomach (4.9)
Europeans did not have their origin in Africa but in Northern Siberia from where most Europeans arrived in wave after wave of migrations by herders rather than hunter gatherers much like the current people of Mongolia. That is why we have white skins and blue/green eyes due to the lack of exposure to sunlight and why we are mainly carnivores who do not have carnivore teeth since we learned to cut up and cook our prey. Slow twitch muscles matched the herder lifestyle and the animals provided the fat. Africans who chased down animals have different bone structure in the calf to foot ratio which is why Ethiopians and Kenyans win the Gold medals at the Olympics in the marathon. It is likely that some African tribes like the Masai have a different muscle fibre ratio to Europeans judging by how high they can jump and for how long.
This is so helpful. Thank you both for taking the time. 😊
When all of this nonsense about eating meat and eggs, protein , fat etc several times daily at 365 days a year has passed , individuals such as myself will still be keeping to what we know works best for the individual, genetics, body type, etc and my ability to function ar such a high level now at age 60 is outstanding, for me a high carbohydrate Whole foods plant based approach is perfect, sustained energy, and cat like agility has changed very little in several decades....
@@Starchaser63 Great to hear! Well done. Keep doing what you’re doing and I also can’t wait until this nonsense passes.
So, what are these minimalists runners doing on race day? Let's sayfor a 5k. Are they racing in the minimalist shoes or do they switch to the carbon plate (assuming they also practiced in them now and then).
Thank you, very good discussion. @1h6min on Metastasis if I understood correctly there is a mechanical mechanism where higher flow through the vascular system prevents cancer cells from establishing themselves in the tissue as well as damaging the cancer cells. Also, there is a boost in immune health which can deal with cancer cells in their early stage. I recall a study presented by Prof Jant Lord who showed that long term older cyclists has preserved thymus function and therefore much better immune system on the order of 2 or 3 decades younger for those in their 70s.
@24:22 he made a claim that 60% plus barefoot runners landed rear foot. Had to check on that. What I found is a couple of experiments that took “mature” or “experienced” athletes and attempts to see what happens when you take their shoes off. These are not barefoot runners. They were single day soft treadmill tests or tests with little to no familiarization and not enough time to adopt the title of barefoot or minimalist runner. Personally I don’t know how import this is anyway, as most trainers now focus on tibial shank angle with 90 degrees being preferable (he does talk about this @39:00). @58:40, Bryan does make a good point that retraining to forefoot takes months to strengthen ankle tendons, tissues, but I believe it’s a small price to pay for the amount of injuries one can accumulate over years and decades of runs. Love these podcasts by the way…very stimulating.
It took me some months to adapt to minimal shoes, but they allow me to run without pinching my toes. There are also other benefits from wearing them for both everyday use and running.
Another gem ❤ Thanks for your work and time
Mr .drave did such a amazing job ...so greatful to heard this podcast ...hats off sir
There is more Melatonin produced and used in peripheral cells during the day than the brain at night. Unlike the melatonin produced in the brain that is linked to the light-dark cycle and influences the circadian master clock , in peripheral tissue It is produced in response to sunlight, especially near infra red and has a neuro-protective, antioxidant and endocrine/paracrine signaling role in cell function especially that of the mitochondria. The brain clock specifically responds to the red light at dawn and sunset and is disrupted by blue light at those times. There is a whole research literature concerning reversal of circadian rhythms in persons working night shifts, submariners and pilots on night flights.
The relaxed style of the chat partnered with the information supported my ability to absorb the information. I’m new to this channel, I am keen to hear more.
Gait and injury. Intriguing. Enjoy 🏋♂️🏊🦊🧨
Sttttooop interrupting the speaker!
Enough with the 'OK' interruptions..
Great video! People like the Glucose Goddess should be addressed.
@@dan-qe1tb I’m very pleased that you enjoyed it! Tbh I hadn’t heard of her and had to Google it. Hmmmm.
@@insideexercise Glucose Goddess is the one who appears to be obsessed with the idea that flattening and lowering glucose spikes is a key to realizing good health. I think she's well intentioned, but misguided. I don't think it's wise to take on unbalanced people in public (and this might be one); it's best to study them quietly and not name them in public. I have pointed people who've been unknowingly misinformed on here, to Nicola's work before. I'm one of the athletes. I've been told that "weight loss and exercise slaughters all else"; and my body fat has become so low that my ribs are protruding (esp when I do more than half an hour of cardio in a day), but my blood sugar is always at a slightly prediabetic level, and the weight loss hadn't helped as much as expected. We're trying to figure out if this is a chronic hepatic problem or not. The overnight glucose reading has been higher than the two and the three hour.