Hubert Huang - Broad Institute
: Ubiquitin-specific proximity labeling to detect E3 substrate ubiquitylation.
Rosa Barrio and James D. Sutherland - CIC bioGUNE
: BioE3 identifies specific substrates of ubiquitin E3 ligases
Sagar Bhogaraju and Christian Behrends - EMBL / Ludwig-Maximilians-University
: A ubiquitin-specific, proximity-based labeling approach for the identification of ubiquitin ligase substrates
About Dana-Farber Targeted Protein Degradation Webinar Series:
Targeted protein degradation (TPD) is a rapidly growing interdisciplinary area of research of both basic science and translational importance. TPD is primarily concerned with the development of agents that induce degradation of protein targets. The precise removal of the target is often linked to a therapeutically beneficial phenotype, making TPD of high interest for drug discovery and development.
This webinar series brings together the community of scientists interested in TPD and rapid dissemination of knowledge and best practices. To learn more and join the future webinars please visit: www.danafarbertargetedproteindegradation.org