R in Pharma
R in Pharma
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Leveraging ChatGPT in Statistical Programming in the Pharmaceutical Industry - Ian Sturdy
This presentation explores the potential benefits of incorporating ChatGPT, a state-of-the-art natural language processing model, in statistical programming within the pharmaceutical industry. By leveraging ChatGPT's capabilities, this technology can save time, money, and most importantly, your sanity. Programming often leads to frustration, anxiety, and sleepless nights trying to solve complex problems. Various applications and techniques that harness the power of ChatGPT will be described to reduce all of these. In a world where artificial intelligence threatens to take our jobs, this paper suggests methods of tapping into the untapped potential of ChatGPT to empower programmers with innovative tools, thereby increasing their value. When programming issues arise, no longer will you need to worry about judgement or hostility from others on online forums, particularly the wrath experienced when not including a reproducible example. ChatGPT is a powerful tool we have yet to fully leverage, and its benefits extend well beyond our imaginations, let alone this presentation.
Переглядів: 110

Відео

Modelling Regulatory Intelligence with GenAI - Jake GagnonModelling Regulatory Intelligence with GenAI - Jake Gagnon
Modelling Regulatory Intelligence with GenAI - Jake Gagnon
Переглядів 443 дні тому
This research introduces an innovative GenAI approach to enhance regulatory compliance in the pharmaceutical industry. Faced with evolving FDA and EMA regulations, pharmaceutical companies struggle with manual, error-prone processes for updating internal documents. Our study proposes a two-step AI-driven solution to streamline regulatory update management. Step 1 employs semantic search to iden...
Rapid Absorption of Dataset Knowledge through GPT-Enhanced Documentation - Melanie HullingsRapid Absorption of Dataset Knowledge through GPT-Enhanced Documentation - Melanie Hullings
Rapid Absorption of Dataset Knowledge through GPT-Enhanced Documentation - Melanie Hullings
Переглядів 333 дні тому
This talk addresses the challenges in effectively leveraging the full capabilities of Large Language Models (LLMs) for data extraction: creating effective knowledge corpora and learning workflow options. We'll explore strategies for handling diverse file formats including PDFs, CSVs, Excel sheets, and unstructured text, as well as data volume limitations. The presentation will demonstrate pract...
Supporting the Medical Writing Process with R, Shiny, and GenAI - Robert Adams & Matthew KumarSupporting the Medical Writing Process with R, Shiny, and GenAI - Robert Adams & Matthew Kumar
Supporting the Medical Writing Process with R, Shiny, and GenAI - Robert Adams & Matthew Kumar
Переглядів 393 дні тому
Medical writers play a critical role in the development of clinical study report (CSR) documents by synthesizing and organizing data from clinical trials. They collaborate closely with researchers, statisticians, and other experts to ensure that the CSR accurately and comprehensively presents the study findings in adherence to regulatory guidelines. This involves incorporating the study protoco...
Digesting the Landscape of LLMs & Successfully Adopting them in Regulatory Contexts - Devin PastoorDigesting the Landscape of LLMs & Successfully Adopting them in Regulatory Contexts - Devin Pastoor
Digesting the Landscape of LLMs & Successfully Adopting them in Regulatory Contexts - Devin Pastoor
Переглядів 373 дні тому
Devin Pastoor shares a comprehensive overview of the current landscape of Large Language Models (LLMs) and details key concepts that underpin their strengths and limitations, as well as sharing the components that make up solutions built around LLMs, and highlights tips for success to adopt LLMs in an organization.
Integrating GenAI with Open-Source for Insights Generation to Boost Efficiency - Vincent ShenIntegrating GenAI with Open-Source for Insights Generation to Boost Efficiency - Vincent Shen
Integrating GenAI with Open-Source for Insights Generation to Boost Efficiency - Vincent Shen
Переглядів 1483 дні тому
Over the past 7 years, NEST packages have been established as a default toolkit for generating clinical insights at Roche. Starting this year, all the new clinical trials will adopt NEST tools by default for their reporting events. To reduce change management burden and boost data scientist’s productivity and efficiency at work, we started leveraging the latest GenAI technologies and built a ch...
Hands-on Session: GenAI to Enhance Your Statistical Programming - Phil Bowsher & Cole ArendtHands-on Session: GenAI to Enhance Your Statistical Programming - Phil Bowsher & Cole Arendt
Hands-on Session: GenAI to Enhance Your Statistical Programming - Phil Bowsher & Cole Arendt
Переглядів 643 дні тому
GenAI in Pharma 2024 kicks off with Posit's Phil Bowsher and Cole Arendt leading an interactive session on utilizing generative AI tools to enhance statistical programming. Resources mentioned in the session: * PharmaSUG workshop "GenAI to Enhance Your Statistical Programming": colorado.posit.co/rsc/genai_R_pharmasug/slides.html * AI Exploration and Innovation for the Clinical Data Scientist: w...
R/Pharma APAC CommitteeR/Pharma APAC Committee
R/Pharma APAC Committee
Переглядів 10915 днів тому
An introduction from the R/Pharma APAC Committee
Introduction to Machine Learning with {tidymodels}Introduction to Machine Learning with {tidymodels}
Introduction to Machine Learning with {tidymodels}
Переглядів 2,5 тис.9 місяців тому
Workshop recorded as part of the R/Pharma Workshop Series (October 18, 2023) Instructors: Nicola Rennie (Lancaster University) Resources mentioned in the workshop: - github.com/nrennie/r-pharma-2023-tidymodels - nrennie.github.io/r-pharma-2023-tidymodels - bookdown.org/max/FES/ - vetiver.rstudio.com/ - www.tidymodels.org/learn/ - www.tmwr.org/
Introduction to Unveiling OPS Cell Patterns with PythonIntroduction to Unveiling OPS Cell Patterns with Python
Introduction to Unveiling OPS Cell Patterns with Python
Переглядів 1009 місяців тому
Workshop recorded as part of the R/Pharma Workshop Series (October 19, 2023) Instructor: Sergio Hleap (Progogia)
{targets} & {crew} for Clinical Trial Simulation Pipelines{targets} & {crew} for Clinical Trial Simulation Pipelines
{targets} & {crew} for Clinical Trial Simulation Pipelines
Переглядів 4909 місяців тому
Workshop recorded as part of the R/Pharma Workshop Series (October 18, 2023) Instructor: Will Landau (Eli Lilly) Resources mentioned in the workshop: - wlandau.github.io/rpharma2023 - github.com/wlandau/rpharma2023 - github.com/wlandau/rpharma2023-pipeline - books.ropensci.org/targets/random.html - wlandau.github.io/crew.cluster/reference/crew_controller_slurm.html
Advanced Exploratory Visualization TechniquesAdvanced Exploratory Visualization Techniques
Advanced Exploratory Visualization Techniques
Переглядів 6349 місяців тому
Workshop recorded as part of the R/Pharma Workshop Series (October 23, 2023) Instructor: Omar ElAshkar (University of Florida) Resources mentioned in the workshop: - omarashkar.github.io/rinpharma2023/slides.html - github.com/OmarAshkar/rinpharma2023 - plotly-r.com/ - statisticsglobe.com/r-assign-fixed-colors-to-categorical-variables-in-ggplot2-plot - www.cedricscherer.com/2021/07/05/a-quick-ho...
Introduction to the PharmaverseIntroduction to the Pharmaverse
Introduction to the Pharmaverse
Переглядів 5839 місяців тому
Workshop recorded as part of the R/Pharma Workshop Series (October 20, 2023) Instructors: Ari Siggard Knoph (Novo Nordisk), Ross Farrugia (Roche) Resources mentioned in the workshop: - github.com/RConsortium/rtrs-wg - posit.co/blog/creating-adsl-with-the-pharmaverse-part-2/ - pharmaverse.github.io/admiral/cran-release/reference/ - phuse-org.github.io/E2E-OS-Guidance/ - join.slack.com/t/pharmave...
Visual Studio Code for PharmaVisual Studio Code for Pharma
Visual Studio Code for Pharma
Переглядів 2509 місяців тому
Workshop recorded as part of the R/Pharma Workshop Series (October 17, 2023) Instructors: Megan Chiang (ProCogia) Resources mentioned in the workshop: - github.com/procogia/VSCodeforPharmaIntro
Observable PlotsObservable Plots
Observable Plots
Переглядів 1559 місяців тому
Workshop recorded as part of the R/Pharma Workshop Series (October 16, 2023) Instructors: Allison Horst (Observable), Michael Freeman (Observable) Resources mentioned in the workshop: - Workshop slides docs.google.com/presentation/d/1KLndrM0obCuDQcTwu04dwqrnpVTpoWUNULcdm3A7bLY/edit?usp=sharing - Workshop notebook (follow-along) observablehq.com/@observablehq/r-pharma-2023-follow - Workshop note...

КОМЕНТАРІ

  • @sunilgupta2156
    @sunilgupta2156 10 днів тому

    Great information! Thanks for sharing this video.

  • @adamsaffron6721
    @adamsaffron6721 25 днів тому

    What indentation style is used at 29:00? How would this look linted?

  • @dkaczmarek9140
    @dkaczmarek9140 Місяць тому

    Thank you for your presentation. I wish I would have had opportunity to work on this transition. Really seems like it is so helpful to the company also helpful to SAS programmers to transition in their career as this is the way things are going. Look at the job requirements, all of these other languages are now, wanted.

  • @JD-xu6py
    @JD-xu6py 2 місяці тому

    Quarto is great! And even better than Latex can use Quarto with Typst!

  • @canarese
    @canarese 3 місяці тому

    Its great for learning. I am getting errors such as Deprecated etc. Have any updated one?

  • @kennedymwavu
    @kennedymwavu 3 місяці тому

    this is so cool!

  • @Smackerz1988
    @Smackerz1988 3 місяці тому

    Someone's an AEW Fan

  • @hemantishwaran5741
    @hemantishwaran5741 3 місяці тому

    Really great. Just wish you’d do things in base R. I’m an advanced user and avoid ggplot and tidyverse so wish you’d stop pushing those tools

    • @suryoputr9344
      @suryoputr9344 3 місяці тому

      I'm a newbie in R. Can you explain why would you avoid ggplot and tidyverse? Is there something inherently wrong in them?

    • @hemantishwaran5741
      @hemantishwaran5741 3 місяці тому

      @@suryoputr9344 As a developer, simpler is better. You want code that is easy to debug, easy to understand, and that will stand the test of time. Just using one command of tidyverse in an R package commits you to its ridiculously large number of dependencies which makes your code less stable. As for ggplot, it produces beautiful figures very quickly, but for EDA purposes you don't often need that and you will end up wasting time. Especially if you want to tweak your plot in any way that is different. As a newbie, you might appreciate the ease at which you can generate high quality graphics and the seemingly easy way to manipulate data with tidy verse, but as you get more advanced you will recognize them as being overly complicated.

    • @djangoworldwide7925
      @djangoworldwide7925 2 місяці тому

      ​@@suryoputr9344No reason. Learn and use the tidyverse.

  • @eubutuoy
    @eubutuoy 3 місяці тому

    What if you need to optimize two parameters from two different studies? For example, ka from oral bolus in vivo data and clearance from iv study? How do you optimize ka and clearance to fit both studies with one pbpk model?

  • @sunilgupta2156
    @sunilgupta2156 3 місяці тому

    Thanks for a great presentation!

  • @mursalimali1629
    @mursalimali1629 4 місяці тому

    O

  • @marwolaeth111
    @marwolaeth111 4 місяці тому

    That's fascinating! 🤩 Your team makes some of my dreams come true. I'll try my best to make the best use of it

  • @johnhhu2137
    @johnhhu2137 4 місяці тому

    cool

  • @haraldurkarlsson1147
    @haraldurkarlsson1147 5 місяців тому

    This is a very well constructed lecture and reproducible (all the data and source code is given on github). A nice scaffold to build your own lectures on and expand. My only complaint is that the transitions are often not clear and bit rugged (e.g. spend a lot time on LASSO but then use Logistic Regression).

  • @haraldurkarlsson1147
    @haraldurkarlsson1147 5 місяців тому

    If you are worried about which columns are picked in step_normalize() and you all want columns with values greater than 1 then I believe this code works: step_normalize(where(~is.numeric(.x) && any(.x > 1))). Now what the author uses in the video is more straight forward and thus simpler but if you have a lot of columns the first approach might be safer.

  • @haraldurkarlsson1147
    @haraldurkarlsson1147 5 місяців тому

    It is hard to sit there and look at a relatively small font (I know you can expand the view) on a light background and not get eye strain. I recommend using a dark background in RStudio.

  • @haraldurkarlsson1147
    @haraldurkarlsson1147 5 місяців тому

    If you are starting out with tidymodels then yo might be confused since a little of details are left out. Naturally you cannot cover such a big subject in a short lecture. Those needing more information might want to look at "Tidy Modeling with r" by Kuhn and Silge(2022). A free ebook version is available online.

  • @PositPBC
    @PositPBC 5 місяців тому

    Really nice talk. Thank you for pioneering this work!

  • @dexterpante
    @dexterpante 5 місяців тому

    Great video tutorial, looking forward for more {Teal} Tutorial

    • @RinPharma
      @RinPharma 5 місяців тому

      We hope to have more at R in Pharma 2024 October 29, 30, & 31st. Workshops will run the week before.

  • @300yardcarry
    @300yardcarry 5 місяців тому

    cool!

  • @vinitakale8823
    @vinitakale8823 6 місяців тому

    On running the following code snippet # Baseline Characteristics ---- adsl_bl <- pre_adsl %>% derive_vars_transposed( select(vs, USUBJID, VSTESTCD, VSSTRESN, VSBLFL), # Dataset to transpose and merge onto by_vars = vars(USUBJID), # Merge keys key = VSTESTCD, # Names of transposed variables value = VSSTRESN, # Values of transposed variables filter = VSTESTCD %in% c("HEIGHT", "WEIGHT") & VSBLFL == "Y" # Restrict records to just height and weight ) %>% # Do some cleanup rename(HEIGHTBL = HEIGHT, WEIGHTBL = WEIGHT) %>% select(-VSBLFL) %>% mutate(BMIBL = compute_bmi(HEIGHTBL, WEIGHTBL)) I am getting the following error. Error in `assert_list_of()`: ! Each element of `arg` must be an object of class/type 'symbol' but the following are not: ✖ Element 1 is an object of class 'quosure' --- Backtrace: ▆ 1. ├─pre_adsl %>% ... 2. └─admiral::derive_vars_transposed(...) 3. └─admiraldev::assert_vars(by_vars) 4. └─admiraldev::assert_list_of(arg, "symbol", named = expect_names, optional = optional) Run rlang::last_trace(drop = FALSE) to see 1 hidden frame. Can you please guide?

  • @carvalhoribeiro
    @carvalhoribeiro 7 місяців тому

    Great presentation. Thanks for sharing this.

  • @siriyaksiriyak6067
    @siriyaksiriyak6067 8 місяців тому

    good refresher, 😇

  • @ivorycloudofficial
    @ivorycloudofficial 8 місяців тому

    Can you add timestamps/sections to your video please?

  • @haraldurkarlsson1147
    @haraldurkarlsson1147 8 місяців тому

    This is excellent! I like the level of depth.

    • @RinPharma
      @RinPharma 5 місяців тому

      Great to hear! We hope to have more at R in Pharma 2024 October 29, 30, & 31st. Workshops will run the week before.

  • @abuyasinsabdahany3259
    @abuyasinsabdahany3259 8 місяців тому

    Thank you

  • @fburton8
    @fburton8 9 місяців тому

    Great demo, so informative! You explained Observable Plots really well.

  • @divanaristoburger8295
    @divanaristoburger8295 9 місяців тому

    This is amazing work!!

  • @gypcasinoable
    @gypcasinoable 10 місяців тому

    The reports are just amazing. Thank you for sharing!

  • @meredith0322
    @meredith0322 10 місяців тому

    I'm able to install ggsurvfit package, but cannot library it. any suggestions for the issue?

    • @RinPharma
      @RinPharma 9 місяців тому

      Hi @meredith0322 - you might ask the question here: github.com/pharmaverse/ggsurvfit/issues

  • @WojtekW-i8j
    @WojtekW-i8j 10 місяців тому

    This is outstanding presentation, I find it very useful. Thank you Daniel! Wojtek. W.

  • @fburton8
    @fburton8 10 місяців тому

    Nice one!

  • @i.meijer-samson3466
    @i.meijer-samson3466 11 місяців тому

    💡

  • @DieuwkeHettinga
    @DieuwkeHettinga 11 місяців тому

    🎉 wat een goede presentatie

  • @mikebartlett6356
    @mikebartlett6356 11 місяців тому

    In 1997 CDISC was formed to harmonise data standards across the industry and there were just as many nay-sayers for that initiative. Their work continues and admiral's is just beginning by comparison. admiral has the potential to make a similar impact on the industry.

  • @newbestofthis4422
    @newbestofthis4422 11 місяців тому

    Thank you! I signed up for this course when it first came out and Ilove it. I look forward to taking your new course. As a biostatistician in public health I was desperate to learn pharmaceuticals workflow and their reporting system, there isn't enough resources unfortunately especially for R.

  • @RinPharma
    @RinPharma 11 місяців тому

    Connect with Michael on LinkedIn, if you’d like to continue the discussion after r/pharma: www.linkedin.com/in/michaelrimler/

  • @RinPharma
    @RinPharma 11 місяців тому

    Project GitHub: github.com/phuse-org/OSTCDA Join the Discussions and leave your perspectives, opinions, links, references, presentations, to help us cultivate a comprehensive digest of the current state of the industry using OS tech for clinical data analytics and reporting

  • @RinPharma
    @RinPharma 11 місяців тому

    Great talk!

  • @tataphani
    @tataphani 11 місяців тому

    Wonderful presentation

  • @ayushgupta7731
    @ayushgupta7731 11 місяців тому

    Amazing

    • @mayank7jan
      @mayank7jan 11 місяців тому

      Thank you 🙏🏻

  • @RinPharma
    @RinPharma 11 місяців тому

    github.com/agstn/RPharma23

  • @abhilashbhagat2949
    @abhilashbhagat2949 Рік тому

    Lovely explanation John!

  • @PotatoesPlease31
    @PotatoesPlease31 Рік тому

    3rd Module starts at 1:14:20 4th Module starts at 1:31:05 5th 1:42:12 6th 2:11:54

  • @nndegwa1
    @nndegwa1 Рік тому

    love it!

  • @chughag
    @chughag Рік тому

    Thank you Micheal, Atorus Research and R in Pharma for conducting this workshop and posting it online!! This is super helpful!!

  • @denizgoktas1535
    @denizgoktas1535 Рік тому

    Thanks for this instructive and worable presentation.

  • @joycesposato5905
    @joycesposato5905 Рік тому

    5:23

  • @Ruben-un1mr
    @Ruben-un1mr Рік тому

    'Promosm' 🙈

  • @explore5709
    @explore5709 Рік тому

    This video puts the mind of SAS Programmer at ease to some extent, that creating a Dataset in R is not that Hard. But at the end of the video it does feel what's will be the future of Clinical Programming ?

    • @nancyanderson5413
      @nancyanderson5413 Рік тому

      Creating dataset is not hard at all in R, and SAS is so expensive, and all the certifications are extremely expensive too. R is a community of scientist, data scientist, and programmers that want people to really learn and understand. Also once you talk with a SAS representative and dig deeper they take a lot of the innovations of the R GNU community. The regular user of SAS does not realized that but the programmers do, and it is awful that a company make a lot of money taking what in reality is open source.