External Medicine Podcast
External Medicine Podcast
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Eliot Siegel, MD: Developing the First Filmless Healthcare Enterprise
In this episode, Daniel Belkin and Mitch Belkin interview Eliot Siegel, MD about developing the first filmless healthcare enterprise at the Baltimore, VA in 1993 which revolutionized the practice of medicine. They discuss the challenges of this innovation, including the costs of computing, the difficulties of imaging compression and data management. They touch on theragnostics, a novel subspecialty in nuclear medicine, which utilizes molecular treatments to target cancer.
00:01:05 - Financial Disclosures
00:03:32 - Intellectual Background and History
00:09:56 - Radiology Pre-1993 & the Baltimore VA
00:15:18 - PACS
00:24:05 - Cost challenges in computing
00:25:34 - Image compression challenges
00:29:46 - Data management challenges
00:31:04 - Creating a new medium for image capture
00:31:50 - Solving transitional barriers with digitizing radiography
00:45:30 - Innovation in a bureaucratic environment
00:52:23 - What is theragnostics?
01:02:40 - Creating United Theranostics
01:09:41 - Effectiveness of molecular treatments
01:12:43 - Rapid Fire
Who is Eliot Siegel?
Dr. Eliot Siegel is a Professor of Radiology at the University of Maryland School of Medicine. He is a prolific author and speaker, has written over 300 articles on medical imaging and PACS, has edited several books, and given more than 1,000 presentations worldwide. In addition to his interest in digital imaging and PACS, he’s interested in telemedicine, the electronic medical record, informatics and artificial intelligence/machine learning. 00:00:00 - Introduction
Переглядів: 88

Відео

Marc Gosselin, MD: Overdiagnosis, Critical Thinking, Burnout, and Other Topics in Radiology
Переглядів 26910 місяців тому
In this episode, Daniel Belkin and Mitch Belkin interview Marc Gosselin, MD about his journey to radiology, being a radiology program director, dealing with burnout, transitioning from academics to private practice, and overdiagnosis in radiology. They discuss in situ thrombosis versus pulmonary emboli, whether medical evidence should have an expiration date, and why physicians should admit fau...
Hussam Alkaissi, MD: Solving Difficult Medical Cases
Переглядів 55511 місяців тому
In this episode, Daniel Belkin and Mitch Belkin interview Hussam Alkaissi, MD about his journey in medicine, experience with populations with high consanguinity, and uncovering of rare diseases. They touch on several unusual cases Hussam has solved including one of CHILD syndrome, homocystinuria, and acute hypercalcemia. 00:00:00 - Intro 00:00:55 - About Hussam 00:03:44 - Populations with High ...
Bryan Carmody, MD: Physician Shortages, Resident Unionization, and the OB/GYN ERAS Divorce
Переглядів 485Рік тому
In this episode, Daniel Belkin and Mitch Belkin interview Bryan Carmody, MD, about physician shortages, resident unionization, and the OB/GYN ERAS divorce. They discuss the recent changes to legislation in Tennessee which allows international medical graduates to bypass the US residency system. They also touch on the Weisman versus Barnes Jewish Hospital court case. Who is Bryan Carmody? Dr. Br...
Joann Elmore, MD: Mammography Guidelines and Other Controversies
Переглядів 143Рік тому
In this episode, Daniel Belkin and Mitch Belkin interview Joann Elmore, MD, about screening mammography. Dr. Elmore shares insights on the USPSTF's new draft mammography recommendations, which lowers the breast cancer screening age from 50 to 40. They discuss the difference in American and European call back rates for biopsy and whether mammography screening programs have substantially improved...
Dan Morgan, MD: Diagnostic Stewardship, Medical Overuse, and Contact Precautions
Переглядів 129Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview infectious diseases physician and epidemiologist Dan Morgan, MD, about infection prevention, diagnostic stewardship, diagnostic reasoning, and medical overuse. They discuss regional differences in medical use and delve into a cluster-randomized controlled trial of contact precautions in ICU patients to evaluate whether this prevents...
Robin Hanson, PhD: Healthcare Signaling, Conspicuous Caring, and Prediction Markets in Medicine
Переглядів 398Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview Robin Hanson, PhD, about healthcare and medicine. They discuss three randomized controlled trials on the population-wide benefits of medicine (RAND health insurance experiment, Oregon Health Insurance Experiment, and the Karnataka Hospital Insurance Experiment), which do not demonstrate benefit for more medical care. They talk about...
How IRBs function as institutional risk management
Переглядів 29Рік тому
Taken from External Medicine Podcast interview with Simon Whitney, MD, JD. Full interview: ua-cam.com/video/WVcS_9h6o44/v-deo.html
How IRBs Exaggerate Research Risk
Переглядів 26Рік тому
Taken from External Medicine Podcast interview with Simon Whitney, MD, JD. Full interview: ua-cam.com/video/WVcS_9h6o44/v-deo.html
Simon Whitney, MD, JD: Unintended Consequences and the Critical Need for IRB Reform
Переглядів 114Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview Simon Whitney, MD, JD, about his book From Oversight to Overkill. They discuss the history of Institutional Review Boards (IRBs), including ethically questionable experiments such as Chester Southam's cancer cell injections, the Willowbrook experiment, as well as the US Public Health Service Syphilis Study (AKA Tuskegee experiment)....
John Ayers, PhD: ChatGPT and the Future of Medicine
Переглядів 559Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview John Ayers, PhD, about ChatGPT and its potential to revolutionize the practice of medicine. We delve into his recent JAMA internal medicine study, which evaluated ChatGPT answers to questions posed on the subreddit r/AskDocs. We also touch on responses to his article discussed on a recent Sensible Medicine Podcast. Finally, we discu...
Andrew Foy, MD: Austrian Economics & Medical Conservatism vs Medical Liberalism
Переглядів 219Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview Andrew Foy, MD, about evidence-based medicine, applying Guideline-Directed Medical Therapy (GDMT) to hospitalized patients, and evaluating aggressive versus conservative blood pressure goals in patients with comorbitidies. They discuss Dr. Foy's article on Hayek, critical appraisal of the medical literature, medical conservatism, an...
Parker Rogers: How FDA Deregulation Promotes Medical Device Innovation & Safety
Переглядів 109Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview Parker Rogers about his recent job-market paper "Regulating the Innovators: Approval Costs and Innovation in Medical Technologies" which examines the impact of FDA regulation on innovation, market structure, and product safety. They discuss the FDA's medical device risk classification and his analysis of down-classification events (...
Ross Levine, MD, PhD: Deep Dive on Acute Myeloid Leukemia
Переглядів 649Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview Ross Levine, MD, PhD about Acute Myeloid Leukemia and its treatment. They discuss the different types of leukemias, the history of AML treatment, including chemotherapy and stem cell transplantation. They touch on Graft vs Host Disease, treatment after relapse, and open questions in leukemia, including future trials, and further inv...
Adam J Brown, MD: Rheumatology, The Black Death, and Why Not to Inject Uric Acid into Your Knee
Переглядів 303Рік тому
In this conversation, Daniel Belkin and Mitch Belkin interview Adam J Brown, MD about the field of Rheumatology, autoimmune diseases, and his podcast Rheuminations. They discuss the history of gout, plaquenil, the relationship between infectious diseases and rheumatologic conditions, the inflammasome, vasculitis, autoinflammatory disorders, fibromyalgia, Covid, and much more. 00:04: Introductio...
Saloni Dattani: Peer Review, Division of Labor in Science, and the Genetics of Psychiatric Disorders
Переглядів 179Рік тому
Saloni Dattani: Peer Review, Division of Labor in Science, and the Genetics of Psychiatric Disorders
Polly Matzinger, PhD: Dangerous Ideas in Immunology
Переглядів 2,1 тис.2 роки тому
Polly Matzinger, PhD: Dangerous Ideas in Immunology
Derek Lowe, PhD: A Medicinal Chemist’s Thoughts on Drug Discovery and the Future of Pharma
Переглядів 2,5 тис.2 роки тому
Derek Lowe, PhD: A Medicinal Chemist’s Thoughts on Drug Discovery and the Future of Pharma
Jean Hébert, PhD: Aging, Brain Plasticity, and Replacing the Neocortex
Переглядів 3632 роки тому
Jean Hébert, PhD: Aging, Brain Plasticity, and Replacing the Neocortex
Paul Offit, MD: The Cost of Medical Innovation, DDT and Malaria, and Bivalent Covid-19 Boosters
Переглядів 1,7 тис.2 роки тому
Paul Offit, MD: The Cost of Medical Innovation, DDT and Malaria, and Bivalent Covid-19 Boosters
Carl Schneider, JD: Patient Decision-Making, Informed Consent, and Why IRBs Should Be Abolished
Переглядів 2132 роки тому
Carl Schneider, JD: Patient Decision-Making, Informed Consent, and Why IRBs Should Be Abolished
Adam Cifu, MD: On Ending Medical Reversals and Reimagining Medical Education
Переглядів 3192 роки тому
Adam Cifu, MD: On Ending Medical Reversals and Reimagining Medical Education
Sekar Kathiresan, MD: Pioneering Single Dose Medications to Cure Cardiovascular Disease
Переглядів 8192 роки тому
Sekar Kathiresan, MD: Pioneering Single Dose Medications to Cure Cardiovascular Disease
Joel Topf, MD: Acute Kidney Injury, Contrast-Associated Nephropathy, and Precious Bodily Fluids
Переглядів 9652 роки тому
Joel Topf, MD: Acute Kidney Injury, Contrast-Associated Nephropathy, and Precious Bodily Fluids
John Cochrane, PhD: The Economics of Affordable Healthcare
Переглядів 1,6 тис.2 роки тому
John Cochrane, PhD: The Economics of Affordable Healthcare
Christy Chapin, PhD: Bad Incentives, the AMA, and How US Healthcare Became Dysfunctional
Переглядів 2022 роки тому
Christy Chapin, PhD: Bad Incentives, the AMA, and How US Healthcare Became Dysfunctional
Jason Ryan, MD: Physician Entrepreneurship, Boards and Beyond, and How to Improve Medical Education
Переглядів 7472 роки тому
Jason Ryan, MD: Physician Entrepreneurship, Boards and Beyond, and How to Improve Medical Education
Rick Johnson, MD: Fructose, Metabolic Syndrome, and Bipolar Disorder
Переглядів 1,1 тис.2 роки тому
Rick Johnson, MD: Fructose, Metabolic Syndrome, and Bipolar Disorder
Nikhil Krishnan: Healthtech Startups, Dank Memes, and Zero to One in Healthcare
Переглядів 2702 роки тому
Nikhil Krishnan: Healthtech Startups, Dank Memes, and Zero to One in Healthcare
Robert Montgomery, MD: Immunology, Pig Organs, and the Future of Xenotransplantation
Переглядів 3312 роки тому
Robert Montgomery, MD: Immunology, Pig Organs, and the Future of Xenotransplantation

КОМЕНТАРІ

  • @TheBoyzTurf
    @TheBoyzTurf 16 днів тому

    In the Information Age it’s a wonder how our brain’s processing power can attempt to keep up or remain stable with an unending bombardment of content and stimuli

  • @fractalentanglement8485
    @fractalentanglement8485 3 місяці тому

    Regarding your question to Karl at 44:00 - what about schizotypy? isn't it considered a station on the way to schizophrenia - an intermediate state? the low latent inhibition seen in schizotypy seems to confer a certain degree of noticing that is not present in neurotypical people. given the much higher prevalence of schizotypal personality disorder, schizotypy seems to be deserving of similar attention.

  • @alaskabarb8089
    @alaskabarb8089 6 місяців тому

    Everyone should be watching this. Learned about the serum osmolarity fat trigger. I always wondered about camels’ humps and metabolic water.

  • @dreamweaver5355
    @dreamweaver5355 7 місяців тому

    0talks too fast, talks in circles..Hard to understand!!!!!!!!!!!!!!!!!!!!!!!!

  • @dominiqueubersfeld2282
    @dominiqueubersfeld2282 8 місяців тому

    Michael Levin, PhD: Brain Degeneration, Word Salad, and Why Morons Aren’t Special

  • @deetaylor334
    @deetaylor334 9 місяців тому

    We ain’t getting into heaven with this one 🔥

  • @jillanderson8292
    @jillanderson8292 10 місяців тому

    Very interesting. I took care of a patient when I was in nursing school that told me that the coffee they brought her everyday was just dark or dyed water, not real coffee. I graduated and worked many years; yet now I have been declared “insane” with schizophrenia myself, and I still think of that woman who told me that when I assessed her during breakfast on clinicals that morning!!! Kind of amusing!

  • @NaeemRiaz
    @NaeemRiaz 10 місяців тому

    If a PA/NP can practice straight out of school, then IMG/residents should be able to practice as well, albeit I think they should be under direct supervision for a few months.

  • @KiKi70236
    @KiKi70236 11 місяців тому

    I loved this. I have AML adverse risk and I am in hospice. Love learning about this disease.

  • @omarlocke4351
    @omarlocke4351 11 місяців тому

    listening to paul offit is harmful to children’s health. nothing this scumbag says can or should be trusted.

  • @satioOeinas
    @satioOeinas 11 місяців тому

    Insane having the “do you have any financial interests to disclose” as your first question 💀

    • @externalmedicinepodcast
      @externalmedicinepodcast 11 місяців тому

      Hey, sorry it sounds strange- it’s standard practice in medicine.

    • @satioOeinas
      @satioOeinas 11 місяців тому

      @@externalmedicinepodcasttotally understandable - thanks for not taking offence in my comment, which was a bit harsh

  • @annenicholsonmbtp
    @annenicholsonmbtp 11 місяців тому

    Wow 😯 one of the best Friston interviews

  • @scottswygert7165
    @scottswygert7165 Рік тому

    Frightening symptoms from hidden Fructose

  • @scottswygert7165
    @scottswygert7165 Рік тому

    This needs a catchier title.

  • @dillydalie11
    @dillydalie11 Рік тому

    I am aml with flt3 too. So basically I am terminal

  • @FishBoneD14
    @FishBoneD14 Рік тому

    Our institution doesn’t have a contract for residents. It’s a letter of agreement

  • @Bear_Arms
    @Bear_Arms Рік тому

    This doctor is amazing. A transplant recipient himself.

  • @bobo-eo2qq
    @bobo-eo2qq Рік тому

    Drug discovery just like lucky draw! None of screening assay system is able to mimic human body. Aging is disease?

  • @kristibradfute
    @kristibradfute Рік тому

    Is this t semagultide known for muscle loss. Does the research also include dexa scans?

  • @YelenaVlogs
    @YelenaVlogs Рік тому

    Dear Dr. Topf, I just wanted to comment that I was underweight with perfect kidney function (eGFR 115). I got a Ct with a contrast without any prehydration because they didn’t deem me high risk. I felt horrible for over a weak when on day 8 I started to urinate about 3 times more than usual with urine color of water. It’s been 6 months and my kidney function hasn’t stabilise 😢I am always thirsty and my urine is always pale or color of water (which I never had before!) I am young with no illness and contrast wasn’t even needed to be administered. They also gave me contrast to drink on that day. There have been absolutely no other drugs for me.

    • @mohammedyussif2835
      @mohammedyussif2835 8 місяців тому

      So sorry to hear that,, i have also got iv contrast 2 months ago and now am having health issues too,. So how do you feel now ?

    • @YelenaVlogs
      @YelenaVlogs 8 місяців тому

      @@mohammedyussif2835I am feeling a little better. But this solution is a true poison. My urine is foamy and eGFR is reduced after it. And I never had kidney problems before. This stuff also damaged my salivary glands and eye and skin oil glands.

    • @YelenaVlogs
      @YelenaVlogs 8 місяців тому

      @@mohammedyussif2835a little better.. what kind of problems are you having?

    • @YelenaVlogs
      @YelenaVlogs 8 місяців тому

      @@mohammedyussif2835my urine is foamy after contrast and eGFR is reduced. Also it damaged my salivary glands and eye and skin glands that produce oil.

    • @mohammedyussif2835
      @mohammedyussif2835 8 місяців тому

      I have muscle cramps, itching , muscle twitching. And my urine is foamy now too, so scared now.

  • @Anabsurdsuggestion
    @Anabsurdsuggestion Рік тому

    Why is it called ‘free energy’? It’s a peculiar term for the principle…

    • @MoreTrenMoreMen69
      @MoreTrenMoreMen69 Рік тому

      I’ve only dabbled in Karl Friston’s ideas so far, but I infer it to refer to the entropy within systems (biological systems, namely the brain in this case). I recall hearing Jordan Peterson’s conversation with Karl Friston (which is a podcast I highly recommend), and in that discussion they discussed the Free Energy Principle essentially is an organisms desire to reduce entropy and randomness in their environment, presumably to ensure survival. As the old saying goes “We fear what we do not know”.

  • @matthewirwin1112
    @matthewirwin1112 Рік тому

    LOVE DEREK LOWE

  • @hosoiarchives4858
    @hosoiarchives4858 Рік тому

    . 1:14:00 Harold burr

  • @FourthWayRanch
    @FourthWayRanch Рік тому

    Pharma hiring goes up and down with the stock market IPO environment. What does that tell ya. I spent decades needlessly exposing myself to chemicals to do nothing more than help crooked venture capitalists get rich. Its astounding how many supposedly smart people can't see this. Read six things big pharma doesn't want you to know by doctors without borders

  • @FourthWayRanch
    @FourthWayRanch Рік тому

    Lowe has never been part of making any drugs. He was pushed out of vertex an wound up with the people who are stealing billions with sacubitril Dont listen to him

  • @FourthWayRanch
    @FourthWayRanch Рік тому

    The internet is filled with pharma hype and spin, infomercials in disguise, they just delete any posts that could hurt sales. Pharma spends a fortune on teams of lawyers that just threaten costly legal action against anyone who challenges them. Their money comes from all the people who overpaid for their prescription meds. The FDA simply isnt qualified to see through the smokescreens. The doctors all file in line like sheep

  • @russellweatherspoon9356
    @russellweatherspoon9356 Рік тому

    Great interview! I always love to hear Polly’s Talk. I hope you get a Nobel prize for your work in immunology regarding the danger model.

  • @JessiChaosTheory
    @JessiChaosTheory Рік тому

    Such a brilliant surgeon and amazing person. ❤

  • @tracik1277
    @tracik1277 Рік тому

    Friston’s obviously not a fan of The Eagles then.

  • @warrenpeece1726
    @warrenpeece1726 Рік тому

    To me BMI is a data point, interesting but less detailed than numbers obtained from blood work. It's really just a part of my positive self image.

  • @sebastianaguiarbrunemeier9192

    Delightful interview, very high IQ content and engagingly presented.

  • @richardbritton4675
    @richardbritton4675 Рік тому

    I look forward to see what you guys put out!

  • @DavidHumeGoat
    @DavidHumeGoat Рік тому

    He is also a great pitcher!

  • @jeremywvarietyofviewpoints3104

    Very important topic. It is explained well.

  • @fhthecat7898
    @fhthecat7898 Рік тому

    Great interview, and great questions. Derek is doing great job of explaining complicated concepts in understandable way. I have been following him for years.

  • @XOPOIIIO
    @XOPOIIIO Рік тому

    Actually when I was a teenager I came up with the idea of elven shit, that smells and tastes very good and have magic properties.

  • @stonecookie
    @stonecookie Рік тому

    Interesting and underrated.

  • @michaelstempkowski9700
    @michaelstempkowski9700 Рік тому

    I have been taking Bydurian for 8 weeks with no major side effects. I am down 48 ins and my life is so much more positive in all areas

  • @Half-code
    @Half-code Рік тому

    No vaccines are safe.

  • @magelinekelley7536
    @magelinekelley7536 Рік тому

    This is very interesting thank you ❤

  • @RitaDrootman
    @RitaDrootman Рік тому

    Great and honest doctor. I am so impressed!

  • @themiscriant
    @themiscriant Рік тому

    This was an amazing interview. Never heard of this podcast, but I love John Cochrane from The Goodfellows. I'll be checking out yalls channel more often now, if this is the sort of stuff yall routinely cover!

  • @katieklaus6833
    @katieklaus6833 Рік тому

    Thank you for covering GLP-1. Probably the most scientific explanation I have heard and you explained it for the layman.

  • @stephensmith6524
    @stephensmith6524 Рік тому

    I would guess (?) that bottom-up thinking is compatible more with deductive thinking, and top-down thinking is more compatible with inductive thinking. But my guess is more a question (also healthy thinking demands both). Moreover, my experience with statistics implies that inductive-loving Bayesians are opposed to deductive-loving frequentists, and timeseries analysis also shows in two "psychological" modes (the linear time domain and the whimsical frequency domain). These are more implied questions, obviously.

  • @gretchensaaduddin5123
    @gretchensaaduddin5123 Рік тому

    Polly....this was amazing. As you may remember, I started out in music, then to music education, then to ethnomusicology. I also was pushed to go into medicine after I passed Part One of the Urology Board Exams (three professors offered to put me through med. School, but I declined). I still remember the fun we had in our various music performance groups, and our long commutes. In high ((LBHS) my name was Gretchen Wetzel (flute, piccolo and a few other instruments). I loved hearing about your work.

  • @OceanFrontVilla3
    @OceanFrontVilla3 Рік тому

    Pathetic.. the vast majority of remarks have been removed. Surprise! Greatest crime in history; "Safe and effective".

  • @carolmcgaghey6112
    @carolmcgaghey6112 Рік тому

    Put ofgitt in jail for life

  • @rajeevgangal542
    @rajeevgangal542 Рік тому

    I have been following his blog for a decade or more now and generally like his balanced takes. However I while I acknowledge that computational methods and AI sometimes overpromise, the fault is also of experimentalists who dont take it seriously and produce data to improve models. No good data no we'll performing models. And yet that's not the impression people may get from reading his blog. Another peeve is the rake that we do not need many Ph.D's now as demand is artificially inflated. True perhaps but then most of these people should practice or and not add this to their name like in this podcast interviewer name. But yeah I'm general great guy and scientist not withstanding pet peeves.

    • @FourthWayRanch
      @FourthWayRanch Рік тому

      LOL the majority of the activity in the industry is just crooked venture capitalists trying to pull off their pump and dumps. The so calle scientist are either too naive to see it or too desperate for a job to criticize.

  • @cameo2740
    @cameo2740 Рік тому

    wow this needs more views

  • @Rakibrown111
    @Rakibrown111 Рік тому

    I think people need some training in how to talk before doing podcasts, like they do for tv. that nasal american accent just hurts my brain, sounds like a bratty child talking about his stamp collection.