MK MediGuide Lectures
MK MediGuide Lectures
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From Needle to Pill: IV to PO Medication Switch
From Needle to Pill: The Game-Changing IV to PO Medication Switch
Welcome to our channel! In today's video, we'll dive into the IV to PO switch, a crucial practice in healthcare. The IV to PO switch, or intravenous to oral switch, is the transition of antibiotic administration from IV to oral routes. This switch is typically implemented when patients show clinical improvement and can safely handle oral medications.
Shifting from IV to PO therapy within 48 hours for severe infections offers numerous benefits, including cost reduction, timely antibiotic delivery, and enhanced patient comfort. It can even pave the way for early discharge and minimize the risks associated with IV therapy.
To assess eligibility for this switch at the 48-hour mark, consider two key factors. First, ensure the gastrointestinal tract is functioning adequately for oral medication absorption. Second, confirm clinical stability by being fever-free for at least 24 hours and observing a normalized white blood cell count.
Keep in mind that IV to PO conversion eligibility depends on factors like infection severity, patient characteristics, and treatment guidelines. Exclusion criteria for the switch encompass patients with unreliable oral medication responses, conditions necessitating IV therapy (e.g., meningitis), septic shock, and infections demanding prolonged IV therapy.
When considering the switch, ensure suitable oral formulations and absorption for antibiotics like Ciprofloxacin, Clindamycin, Fluconazole, Levofloxacin, Linezolid, Metronidazole, Trimethoprim/sulfamethoxazole, and Voriconazole.
Remember that dosages may vary by country, so consult local guidelines. Thanks for watching! If you found this video helpful, please like, share, and subscribe for more valuable content in our community!
Переглядів: 166

Відео

Meropenem Dose adjustment in Renal failure - Pharmacology
Переглядів 3,3 тис.Рік тому
Meropenem Dose adjustment in Renal failure or Meropenem Dose adjustment in kidney impairment - Pharmacology In this video, we will discuss the dose adjustment of Meropenem based on serum creatinine levels using the Cockcroft-Gault Formula. Meropenem is a commonly used antibiotic, and it is crucial to ensure the appropriate dose is administered to avoid adverse effects and ensure optimal efficac...
Dose Adjustment in Renal Failure by using the Cockcroft-Gault Formula (Posology) - Pharmacology
Переглядів 5 тис.Рік тому
Dose Adjustment in renal failure based on Serum Creatinine by using the Cockcroft-Gault Formula - Pharmacology Understanding Cockcroft-Gault Formula and Creatinine Clearance for Medication Dosing (Posology) Welcome to today's lecture on dose calculation based on serum creatinine levels! As a healthcare professional, it's essential to calculate the appropriate medication dose for a patient based...
Metronidazole (Flagyl) Pharmacology - Mechanism of Action - Amebiasis Treatment
Переглядів 3,6 тис.Рік тому
Metronidazole (Flagyl) Pharmacology - Mechanism of Action, Interaction, Dose - Amebiasis Treatment In this video, we discuss everything you need to know about Metronidazole - widely known as Flagyl - as a pharmacotherapeutic agent for amoebiasis. We cover its pharmacological class, the spectrum of activity against microorganisms, mechanism of action, chemical structure, pharmacokinetics, advers...
Nicotine uses & smoking
Переглядів 20Рік тому
Nicotine uses and smoking. Full video Link: ua-cam.com/video/Uhp_GivuSQg/v-deo.html Discover the fascinating actions and uses of nicotine in this short video! From its effects on the brain to its potential therapeutic applications, learn all about this powerful alkaloid and its impact on human health. Whether you're a smoker, a healthcare professional, or simply curious about the science behind...
Amoebiasis: Pharmacotherapy & Classification of amebicidal agents - Pharmacology
Переглядів 514Рік тому
Amoebiasis: Pharmacotherapy & Classification of amebicidal agents - Pharmacology The video discusses the pharmacotherapy of amebiasis and classifies the therapeutic agents into three categories: luminal amebicides, systemic amebicides, and mixed amebicides. The video begins by highlighting the importance of luminal amebicides in eradicating asymptomatic colonization of trophozoites in the intes...
Amoebiasis: Pathophysiology, Life cycle & Pharmacotherapy - Pharmacology
Переглядів 1,7 тис.Рік тому
Amoebiasis: life cycle, Types & pharmacotherapy - Pharmacology Discover the dark secrets of amoebiasis in this mind-boggling video! Learn about the life cycle of this microscopic beast and how it can wreak havoc on the human body, causing intestinal and extraintestinal infections. You'll also delve into the challenges of treating this protozoan parasite with pharmacotherapy. Don't miss out on t...
Parasympathomimetics: Clinical Uses of Indirect acting cholinergic drugs
Переглядів 561Рік тому
Parasympathomimetics: Clinical Uses, mechanism of action & Classification of indirect-Acting Cholinergic Drugs In this video, we'll discuss Parasympathomimetics, drugs that act on the cholinergic system. We'll also classify the various indirect-acting cholinergic drugs and discuss their clinical uses. If you're interested in cholinergic drugs and their clinical uses, then this video is for you!...
Parasympathomimetics: Clinical Uses & Classification of Direct Acting Cholinergic Drugs
Переглядів 2,3 тис.Рік тому
Parasympathomimetics: Clinical Uses & Classification of Direct-Acting Cholinergic Drugs In this video, we'll discuss parasympathomimetics, drugs that act on the cholinergic system. We'll also be classifying the various direct-acting cholinergic drugs and discussing their clinical uses. If you're interested in cholinergic drugs and their clinical uses, then this video is for you! By the end of t...
Myasthenia Gravis: Overview, Pathophysiology, Symptoms and Treatment | Pharmacology
Переглядів 7 тис.2 роки тому
Myasthenia Gravis Pharmacology | Pathophysiology | Symptoms | Neostigmine This video is all about the Myasthenia Gravis. myasthenia gravis is an autoimmune disease of the neuromuscular junctions, in which autoimmune antibodies produced by B cells bind to the nicotinic acetylcholine receptors on the nuromuscular end plate in the neuromuscular junction. this attachment inhibits the acetylcholine ...
Neuroglia | Glial cells | Nervous system - pharmacology
Переглядів 4262 роки тому
Neuroglia | Glial cells | Nervous system - pharmacology This video is all about the neuroglia or glial cells that are sometimes known as non-neural as well. neuroglial cells are the supporting cells of the CNS and are 5 to 15 times greater in number than neurons. neuroglia or glial cells fill spaces, provide the structural framework, produce myelin and carry on phagocytosis. neuroglia or glial ...
Cholinergic Drugs: Pharmacological Action, Indirect Acting Drugs, and Anticholinesterases
Переглядів 8543 роки тому
Cholinergic Drugs: Pharmacological Action, Indirect Acting Drugs, and Anticholinesterases
Adrenergic transmission Pharmacology | synthesis and release of norepinephrine
Переглядів 8 тис.3 роки тому
Adrenergic transmission Pharmacology | synthesis and release of norepinephrine
Cholinergic Drugs: Pharmacological actions of Parasympathomimetics, Direct acting drugs
Переглядів 1,5 тис.3 роки тому
Cholinergic Drugs: Pharmacological actions of Parasympathomimetics, Direct acting drugs
Cholinergic drugs: Parasympathomimetics classification and mechanism of action
Переглядів 10 тис.3 роки тому
Cholinergic drugs: Parasympathomimetics classification and mechanism of action
Therapeutic index - Pharmacology
Переглядів 17 тис.3 роки тому
Therapeutic index - Pharmacology
Cholinergic transmission | acetylcholine synthesis & metabolism | cholinergic drugs | pharmacology
Переглядів 3,5 тис.3 роки тому
Cholinergic transmission | acetylcholine synthesis & metabolism | cholinergic drugs | pharmacology
First Pass Effect | First pass metabolism | Pharmacology | pharmacokinetic
Переглядів 7 тис.3 роки тому
First Pass Effect | First pass metabolism | Pharmacology | pharmacokinetic
Cholinergic receptors | Muscarinic and Nicotinic receptors - Pharmacology
Переглядів 6 тис.3 роки тому
Cholinergic receptors | Muscarinic and Nicotinic receptors - Pharmacology
sympathetic vs parasympathetic nervous system | Autonomic nervous system - Pharmacology
Переглядів 7113 роки тому
sympathetic vs parasympathetic nervous system | Autonomic nervous system - Pharmacology
Parasympathetic nervous system - Pharmacology | Autonomic nervous system
Переглядів 8143 роки тому
Parasympathetic nervous system - Pharmacology | Autonomic nervous system
Sympathetic nervous system - Pharmacology | Autonomic nervous system
Переглядів 1 тис.3 роки тому
Sympathetic nervous system - Pharmacology | Autonomic nervous system
Autonomic nervous system - Pharmacology | ANS- sympathetic & parasympathetic
Переглядів 1,1 тис.3 роки тому
Autonomic nervous system - Pharmacology | ANS- sympathetic & parasympathetic
Classification of neurons | Nervous system
Переглядів 5 тис.3 роки тому
Classification of neurons | Nervous system
Neuron | Neuron Structure | Nervous system
Переглядів 4273 роки тому
Neuron | Neuron Structure | Nervous system
Cerebrum | Lobes and physiologic regions of the cerebrum | Nervous system
Переглядів 6043 роки тому
Cerebrum | Lobes and physiologic regions of the cerebrum | Nervous system
Divisions of the nervous system | CNS & PNS divisions | Nervous system
Переглядів 1 тис.4 роки тому
Divisions of the nervous system | CNS & PNS divisions | Nervous system
Cytochrome P450 isozymes - pharmacology | CYP450 isoforms | CYP3A4
Переглядів 4,9 тис.4 роки тому
Cytochrome P450 isozymes - pharmacology | CYP450 isoforms | CYP3A4
Cytochrome P450 drug metabolism - Pharmacology | mechanism of CYP drug metabolism
Переглядів 17 тис.4 роки тому
Cytochrome P450 drug metabolism - Pharmacology | mechanism of CYP drug metabolism
COVID-19 & vitamin D deficiency in aging -p3 | Cytokine storm |SARS-CoV2
Переглядів 5004 роки тому
COVID-19 & vitamin D deficiency in aging -p3 | Cytokine storm |SARS-CoV2

КОМЕНТАРІ

  • @minabish1783
    @minabish1783 2 дні тому

    Wby does it cause something on lower doses but something else on higher doses, how doez thar work?

    • @MKMediGuideLectures
      @MKMediGuideLectures День тому

      Depends on drug. Mainly due to drug receptor interactions like whether the drug is full agonist or partial agonist and also the type of receptors to which it binds.

  • @mdshan6353
    @mdshan6353 2 місяці тому

    one of the fine explanation video i ever saw thanks for posting this video

  • @mrmc55
    @mrmc55 3 місяці тому

    ❤❤❤

  • @gloryndjambi8373
    @gloryndjambi8373 4 місяці тому

    This is very very helpful. Thank you

  • @Rxconsultants
    @Rxconsultants 5 місяців тому

    Amazing 👏

  • @vardhinin.s4999
    @vardhinin.s4999 7 місяців тому

    Due to amibieosis dizziness can come?

  • @chaitanya.gatade2080
    @chaitanya.gatade2080 7 місяців тому

    helpful

  • @arbajpathan011
    @arbajpathan011 7 місяців тому

    Amobic colitis Treatment please

  • @M0-w
    @M0-w 8 місяців тому

    Dont speak in english

  • @AcalmInTheChaos
    @AcalmInTheChaos 9 місяців тому

    Very insightful

  • @FatimaWaleed-y3z
    @FatimaWaleed-y3z 10 місяців тому

    🙏🏻

  • @sereena6892
    @sereena6892 10 місяців тому

  • @prettypuff1
    @prettypuff1 11 місяців тому

    Wow this is great content

  • @tariqhassan3046
    @tariqhassan3046 11 місяців тому

    Thank you...

  • @KalsoomInsights
    @KalsoomInsights 11 місяців тому

    Too much beautiful writing styl and color combination ❤ I really appreciate your hard work👍 it's just amazing 🤩

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Sir... Amoebic ulcers can be seen in ct scan and MRI?

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Sir... Amoebiasis maine... Stool ka colour kaise hota hai?

  • @WajidKhan-vc8bz
    @WajidKhan-vc8bz Рік тому

    Nice work bro🎉

  • @karimkhan431
    @karimkhan431 Рік тому

    Causes of mysthinea Gravis please

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Sir pls make video on typhoid fever....

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      We'll do our best to upload ASAP, but we are re really busy these days. 🙂

    • @zohebmulla3670
      @zohebmulla3670 Рік тому

      @@MKMediGuideLectures ok sir thank u so much 🙏🏻

  • @arbajpathan011
    @arbajpathan011 Рік тому

    Amoebic dysentery and amoebic colitis same

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Amebic dysentery and amebic colitis are closely related but not the same. Amebic dysentery is an acute infection caused by E. histolytica. It typical symptoms are severe diarrhea, abdominal cramps, and bloody stools. On the other hand, amebic colitis (colon + inflamation) refers to a chronic infection of the colon by the same parasite. The usually presented milder symptoms such as intermittent diarrhea, abdominal discomfort, and occasionally bloody stools. While both conditions are caused by the same parasite, they differ in terms of the severity and duration of symptoms.

    • @arbajpathan011
      @arbajpathan011 Рік тому

      @@MKMediGuideLectures amoebic colitis treatment

  • @chilufyabwalyakalebaila9224

    I'm kindly requesting for a video on organophosphate poisoning

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      We'll do our best to upload as quickly as we can, but we're really busy these days. 🙂

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Is meropenem used in typhoid fever ,uti infection and cystitis?

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Meropenem is indicated for multi-drug resistant organisms. While it may have some activity against certain bacteria that can cause UTI, but not considered a first-line for uncomplicated cystitis or UTIs. It is reserved for more severe. As per Typoid fever which is caused by Salmonella typhi, It is not a first line treatment for typhoid fever. Other antibiotics are typically recommended for these conditions based CS report such as Flouroquinolones or 3rd generation CePhs like Ceftriaxone for typoid. Meropenem only used for severe infection and unresponsive to the other standard recommended ABx.

    • @zohebmulla3670
      @zohebmulla3670 Рік тому

      ​@@MKMediGuideLectures ok sir thanks a lot 🙏🏻

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Is lariago suspension or chloroquine phosphate ....is used for amoebic colitis or Amoebiasis?

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Chloroquine is used for intestinal amoebiasis. But not as first line agent. Mostly Metronidazole is used. Chloroquine is used when the other options are limited.

    • @zohebmulla3670
      @zohebmulla3670 Рік тому

      @@MKMediGuideLectures ok sir thank you so much 🙏🏻

  • @Miss-me08
    @Miss-me08 Рік тому

    Awesome stuff here,thanks for making my life easier

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Sir can entamoeba histolytica cause cystitis i.e uti infection?

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Most common extraintestinal amebiasis affect liver, lungs and brain. Kidney are very rarely affected.

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    From swimming pool and waterpark.. We can get Amoebiasis infection?

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Yes! but the chances are low. It is mostly present in poorly maintained swimming pool and Waterpark. Whatever the case, the microorganism only can infect you after reaching to your intestines.

    • @zohebmulla3670
      @zohebmulla3670 Рік тому

      ​@@MKMediGuideLectures ok sir thank u so much 🙏🏻

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Is metronidazole given in typhoid fever for diarrhea?

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      No Dear, There is no indication of METRONIDAZOLE in Micromedex or lexicomp for typhoid fever. Typoid fever is caused by Salmonella typhi. Which is a gram negative microorganism. While MTDZ have action against protozaons and anaerobic bacteria. So, specifically it is not used for typhoid fever. It can be used empirically, if there is a concomitant possible infection with anerobes or protozoans. But when specialist in infectious diseases recommends after observing the patient. Otherwise, not recommended in Typhoid fever Thank you 🙂

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      For this, Other ABX with action against Salmonella typhi are used like Floroquinolones mostly and other like 3rd generation cephalosporins.

    • @zohebmulla3670
      @zohebmulla3670 Рік тому

      @@MKMediGuideLectures ok sir thanks for the detailed information🙏🏻

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Welcome🙂

    • @zohebmulla3670
      @zohebmulla3670 Рік тому

      ​@@MKMediGuideLectures ❤

  • @zohebmulla3670
    @zohebmulla3670 Рік тому

    Is metronidazole given in typhoid fever?

  • @HamidAli-Rph
    @HamidAli-Rph Рік тому

    1st viewer🥰 keep up brooo💓💓💓

  • @WajidKhan-vc8bz
    @WajidKhan-vc8bz Рік тому

    Nice work

  • @HamidAli-Rph
    @HamidAli-Rph Рік тому

    💓💓💓

  • @LetsgoBrendanFJB
    @LetsgoBrendanFJB Рік тому

    AMAAAAZING vídeo! Thank you for spending time on it.🙏🏼 I was about to k*ll myself when a Dr figured out I had ‘NORADRENALINE’ deficiency and it changed my life completely after that - My SEVERE headaches and diarrhoea disappeared and I became a sort of “professional” optimistic and I even moved to another country. After 10 years I’m feeling that I should start to reduce the current dosage = VENLAFAXINE 300mg/day, as I’m feeling VERY tired without will to do anything. Or I needed to find something natural to feed my brain with ‘noradrenaline’. I really appreciate any suggestions.

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Thank you for taking the time to watch my video and for sharing your personal story with us. I am glad to hear that a proper diagnosis and treatment plan improved your quality of life. It's important to note that making any changes to your medication regimen should always be discussed with your healthcare provider. They can assess your current symptoms and help you determine the best course of action. In addition to medication, there are several natural ways to support healthy levels of noradrenaline in the brain. These include exercise, getting enough sleep, and eating a diet rich in nutrients such as vitamin C, iron, and tyrosine. Again, thank you for sharing your story, and I hope you find the support and guidance you need. Regards MK

  • @niveditas7880
    @niveditas7880 Рік тому

    It affects younger women and older men, rectify it.

  • @zeeshanwali216
    @zeeshanwali216 Рік тому

    Sir please tell me How i get your Nots in Hard form

  • @doniaahmed6536
    @doniaahmed6536 Рік тому

    Thanks not enough ❤❤

  • @zeeshanwali216
    @zeeshanwali216 Рік тому

    How I Get Your amazing Notes sir please tell me

  • @HamidAli-Rph
    @HamidAli-Rph Рік тому

    💓💓💓

  • @WajidKhan-vc8bz
    @WajidKhan-vc8bz Рік тому

    Nice work

  • @WajidKhan-vc8bz
    @WajidKhan-vc8bz Рік тому

    Nice

  • @nesmajawahar7926
    @nesmajawahar7926 Рік тому

    What is neuromuscular end plate here ?

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      The endplate is considered a postsynaptic structure because it is located on the muscle fiber, which is the target of the motor neuron's synaptic transmission.

    • @nesmajawahar7926
      @nesmajawahar7926 Рік тому

      @@MKMediGuideLectures Thank u

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Welcome 🙂 If you have benefited from these videos, please share them with your friends🙂

  • @dr.prakharshukla795
    @dr.prakharshukla795 Рік тому

    Great and educative video❤

  • @WajidKhan-vc8bz
    @WajidKhan-vc8bz Рік тому

    Nice work bro

  • @mzaidrasheed5778
    @mzaidrasheed5778 Рік тому

    You nailed it. Bro 🥺

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Thank You😊 Share it with your friends & help us reach big audience🙂💐

  • @WajidKhan-vc8bz
    @WajidKhan-vc8bz Рік тому

    Nice

  • @doctorvolgs7769
    @doctorvolgs7769 Рік тому

    Nice

  • @doctorvolgs7769
    @doctorvolgs7769 Рік тому

    Nice

  • @doctorvolgs7769
    @doctorvolgs7769 Рік тому

    Nice

  • @MKMediGuideLectures
    @MKMediGuideLectures Рік тому

    Thanks for watching Do like and SUBSCRIBE

  • @billy3394
    @billy3394 Рік тому

    So would this make my suboxone last longer ?

    • @billy3394
      @billy3394 Рік тому

      Would it make me absorb more of the opioids in my suboxone prescription?

    • @MKMediGuideLectures
      @MKMediGuideLectures Рік тому

      Please elaborate your question? I'm not sure which part of the video you're referring to in your question? It would be better if you discuss it with your pharmacist or physician there 🙂