GenScript USA Inc.
GenScript USA Inc.
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Відео

Advanced solutions for the development of Gene Therapies
Переглядів 71Місяць тому
Gene therapy involves introducing a functional gene into the patient's cells to replace a missing or defective one. It has revolutionized the field of medicine and has the potential to cure various genetic disorders. The two main technologies used for gene therapy are viral-based and non-viral gene editing. The primary advantage of viral-based gene editing is that viruses are highly efficient a...
Navigate CGT Success Align cGMP Gene Editing with Regulatory Frameworks
Переглядів 31Місяць тому
Cell and gene therapy is at the forefront of medical innovation, offering transformative potential for treating complex diseases. However, achieving success in these therapies requires meticulous attention to the quality of gene editing components and regulatory compliance. This webinar will explore how quality and regulatory standards for gene editing reagents influence the development and app...
Advanced solutions for CRISPR gene editing
Переглядів 338Місяць тому
CRISPR has emerged as a promising alternative to viral-based gene editing by allowing scientists to modify genes with unprecedented ease and flexibility. The discovery and development of a diverse range of CRISPR enzymes, each with its own specificities and modalities (such as CAS-9, CAS-12, CAS-13, and others), is a testament to the robustness of this technology. The new developments in Base a...
Advancing Gene Editing Technologies with Spherical Nucleic Acids
Переглядів 1203 місяці тому
Dr. Sergej Kudruk International Institute for Nanotechnology (IIN) Postdoctoral Fellow, Northwestern University, Department of Chemistry Nanomaterials have already begun to play a pivotal role in overcoming the limitations of traditional drugs by enhancing drug delivery, improving bioavailability, overcoming biological barriers in the treatment and prevention of diseases. Spherical Nucleic Acid...
Autoimmune Diseases, the Arising Opportunities for Cell Therapies
Переглядів 783 місяці тому
Dr. Dong Geng VP, Head of Early-stage Drug Development Legend Biotech CAR-T cell therapies are now the established treatments for patients with relapsed and/or refractory B cell lymphomas, B cell acute lymphoblastic leukemia, and multiple myeloma. Through deep depletion of targeted malignancy cells, CD 19-targeted and BCMA-target CAR-T treatment could lead to long-term remissions, in some cases...
Synthetic biology approaches to improve cell therapy function
Переглядів 873 місяці тому
Dr. Michelle Hung Principal Scientist GeneFab There has been an explosion in the number of genetic medicines, including, cell & gene therapies in clinical development. These therapies contain thousands to billions more atoms than small molecules and biological drugs. Thus the design and manufacturing of these advanced therapies is much more complex than more established therapeutic modalities. ...
The Power of Automation: How Robotics Can Dramatically Reduce Cell Therapy Manufacturing Costs
Переглядів 1543 місяці тому
Dr. Fred Parietti Co-founder and CEO of Multiply Labs There’s an elephant in the room when it comes to cell therapy. Hundreds of thousands of patients are in need of these life saving therapies - but the vast majority can’t access the treatment. This is because cell therapy manufacturing is reliant on a highly-skilled and limited labor pool, which results in prohibitively high prices and lack o...
Programmable Genomic Integration: a technology that enables the integration of large DNA sequences
Переглядів 1153 місяці тому
Dr. Sandeep Kumar Senior Director, Platform Tome Biosciences Tome Biosciences is leading the field of programmable genomic integration (PGI). Building on founding technologies obtained from MIT and Replace Therapeutics, Tome has developed and refined PGI resulting in stable integration of multiple kilobases of DNA at user-defined locations. Integrase-mediated PGI (I-PGI) uses a Cas9 nickase wit...
Cytokine Armored CAR NK Cell Therapy for Advanced Ovarian Cancer
Переглядів 1293 місяці тому
Dr. Branden Moriarity Associate Professor, Medical School, University of Minnesota Immunotherapy using chimeric antigen receptor (CAR) expressing NK cells engineered via viral vectors has shown exceptional efficacy against hematologic cancers in clinical trials. This method, however, is limited in cargo capacity and large-scale manufacturing for clinical use is cost-prohibitive to most academic...
De novo gene synthesis by an antiviral reverse transcriptase
Переглядів 3733 місяці тому
Dr. Samuel Sternberg Associate Professor, Department of Biochemistry and Molecular Biophysics, Columbia University Bacteria defend themselves from viral infection using diverse immune systems, many of which sense and target foreign nucleic acids. Defense-associated reverse transcriptase (DRT) systems provide an intriguing counterpoint to this immune strategy by instead leveraging DNA synthesis,...
4th Annual Gene & Cell Engineering Virtual Summit Recap
Переглядів 564 місяці тому
Watch our recap of the event! Did you miss it or weren't able to attend the entire event? No worries! You can still register now and watch on demand: bit.ly/4cPC9f6
Accelerating Cell & Gene Therapy Success with cGMP Gene Editing Components and Regulatory Compliance
Переглядів 2135 місяців тому
The manufacturing of gene editing (GE) components is a pivotal aspect of GE-based Cell and Gene Therapy development, requiring meticulous attention to product quality and regulatory compliance throughout the development lifecycle. In this webinar, we will discuss the key differences between GE components used from early discovery through to clinical application, and provide insight into how pha...
AI based Antibody Therapeutics Developability Assessment and Its Engineering
Переглядів 3395 місяців тому
Learn from an informative webinar about how AI-based platforms can facilitate the development process for antibody therapeutics and ensure candidates are not only therapeutically effective but also viable for large-scale production and clinical use. Monoclonal antibodies (mAbs) have become essential in treating a wide spectrum of diseases, with over 100 therapeutic antibody products now approve...
AET London 2024: Bispecific Antibody Therapeutics: Challenges, Opportunities and Future Directions
Переглядів 2415 місяців тому
This talk, “Bispecific Antibody Therapeutics: Challenges, Opportunities and Future Directions” was given during the 2024 Antibodies Engineering & Therapeutics Europe meeting in London, UK, by Robert Ford, PhD, Field Application Specialist at GenScript. In this presentation, you will learn about bi-specific antibodies (bsAbs) demonstrating novel functionalities that yield remarkable promise in i...
Streamlining Cell and Ex Vivo Gene Therapy Manufacturing Innovative Solutions from GenScript
Переглядів 1687 місяців тому
Streamlining Cell and Ex Vivo Gene Therapy Manufacturing Innovative Solutions from GenScript
Complete Toolbox for Gene Therapy Development with Live Q&A
Переглядів 1577 місяців тому
Complete Toolbox for Gene Therapy Development with Live Q&A
Advanced Solutions for mRNA Vaccine Development with Live Q&A
Переглядів 1267 місяців тому
Advanced Solutions for mRNA Vaccine Development with Live Q&A
Bispecific Antibody Overview & Production with CrossMab Technology
Переглядів 9687 місяців тому
Bispecific Antibody Overview & Production with CrossMab Technology
Advancing Brain Shuttle-Enabled Therapeutics for Efficient Delivery to CNS
Переглядів 2528 місяців тому
Advancing Brain Shuttle-Enabled Therapeutics for Efficient Delivery to CNS
Life Science Research Grant Program
Переглядів 7710 місяців тому
Life Science Research Grant Program
Enhancing Treatments using Targeted Protein Degradation
Переглядів 23610 місяців тому
Enhancing Treatments using Targeted Protein Degradation
The Future of Plasmid Maxi-prep is Here: AmMag™ Quatro Automated Solution
Переглядів 21711 місяців тому
The Future of Plasmid Maxi-prep is Here: AmMag™ Quatro Automated Solution
Robust production of antibody fragments and their therapeutic applications
Переглядів 19511 місяців тому
Robust production of antibody fragments and their therapeutic applications
PEGS Europe 2023: Empowering Therapeutic Antibody Development
Переглядів 9511 місяців тому
PEGS Europe 2023: Empowering Therapeutic Antibody Development
Bispecific Antibodies Structural Design, Production and Purification Strategies
Переглядів 1,6 тис.Рік тому
Bispecific Antibodies Structural Design, Production and Purification Strategies
Best in class antiviral antibodies from cognate recombinant antibody repertoires of human donors
Переглядів 55Рік тому
Best in class antiviral antibodies from cognate recombinant antibody repertoires of human donors
GenScript x XTalks Webinar: Adaptive Immune Response in Narcolepsy Type 1
Переглядів 106Рік тому
GenScript x XTalks Webinar: Adaptive Immune Response in Narcolepsy Type 1
What to Expect from a CRO
Переглядів 132Рік тому
What to Expect from a CRO
What to Expect from a CRO: What can you expect from GenScript once a project starts?
Переглядів 55Рік тому
What to Expect from a CRO: What can you expect from GenScript once a project starts?