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Characterization of Residual Impurities in Gene Therapy Drug Products

1:23:57

MockV® Customer Testimonials

3:48

Generic Vs Process Specific HCP ELISA

3:47

Dilution Linearity and Spike Recovery

3:15

HCP ELISA and HCP Ab Coverage Analysis

3:47

Spike Recovery

5:19

Predicting Viral Clearance Through the Use of Non-Infectious MVM and RVLP Surrogates

Key Learning Objectives
• Learn how viral clearance prediction is possible using non-infectious mock virus particles that mimic the physiochemical properties of live mammalian viruses
• Understand how this approach can be applied to downstream efforts such as design of experiments and high throughput screening, and can help facilitate process development/optimization
• Review several case studies utilizing MockV MVM and RVLP particles in a BSL-1 lab setting

Відео

Characterization of Residual Impurities in Gene Therapy Drug Products

1:23:57

Characterization of Residual Impurities in Gene Therapy Drug Products

Переглядів 867Рік тому

Characterization of residual impurities for gene therapy drug products is particularly challenging due to the complex nature of the final products as well as the complicated processes required to manufacture them. As these products advance through clinical development, the identification, characterization, and control of the process- and product-related impurities are important to define early ...

3:48

MockV® Customer Testimonials

Переглядів 862 роки тому

Downstream process development scientists are overcoming challenges with Viral Clearance studies by utilizing mock virus particles

3:47

Generic Vs Process Specific HCP ELISA

Переглядів 1,4 тис.4 роки тому

Explains the two different types of HCP ELISA, Generic and Process Specific

3:15

Dilution Linearity and Spike Recovery

Переглядів 10 тис.4 роки тому

Dilution Linearity and Spike Recovery are two critical experiments in assessing assay accuracy and specificity.

3:47

HCP ELISA and HCP Ab Coverage Analysis

Переглядів 4,1 тис.4 роки тому

Explanation of Host Cell Protein (HCP) ELISA and HCP Antibody Coverage Analysis www.cygnustechnologies.com/antibody-affinity-extraction-aaetm

5:19

Spike Recovery

Переглядів 8 тис.4 роки тому

Demonstration of the recommended ELISA plate setup and performance of a spike recovery experiment for four samples and controls.

6:39

Protein A Mix-N-Go™ ELISA

Переглядів 1,7 тис.4 роки тому

Demonstrates how to run assays with the Cygnus Technologies' easy-to-use Protein A Mix-N-Go™ ELISA Kits

11:03

Host Cell DNA Extraction Methods

Переглядів 1,5 тис.4 роки тому

Updated video demonstrating Cygnus Technologies' method for extraction of trace levels of DNA from biopharmaceuticals

3:14

What are HCPs? and Why do we care?

Переглядів 2,9 тис.4 роки тому

Explains what are Host Cell Proteins (HCPs) and why they are significant to the development of biopharmaceuticals

Washing Technique for Microtiter Plate - ELISA

5:10

Washing Technique for Microtiter Plate - ELISA

Переглядів 32 тис.4 роки тому

How to wash a microtiter plate This demonstration is an updated version of the recommended technique for the manual microtiter plate washing procedure.

Protein A ELISA - Sample Treatment Procedure for Cygnus' F050H and F400 Kits

4:35

Protein A ELISA - Sample Treatment Procedure for Cygnus' F050H and F400 Kits

Переглядів 1,2 тис.5 років тому

For accurate results when running the original Cygnus Protein A ELISA kits. First time evaluators of Protein A detection methods are encouraged to evaluate the Mix-N-Go™ Protein ELISA Kits, F600 and F610. Mix-N-Go™ ELISA kits are designed to perform with most natural and recombinant Protein A constructs and incorporate the revolutionary single step sample treatment procedure. These kits also re...