Medicinal Genomics
Medicinal Genomics
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What Were Some Surprising Things You Found in the analysis
Kevelin Barbosa-Xavier is a PhD student in Plant Biotechnology at Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) where she conducts research under the supervision of Thiago Motta Venancio. She is a computational biologist, investigating the genes and gene networks involved in plant secondary metabolic pathways and fiber production, specifically in the Cannabis sativa species.
Kevelin and her team recently published a study titled Cannabis Expression Atlas: a comprehensive resource for integrative analysis of Cannabis sativa L. gene expression, along with a free online tool to help researchers analyze genomic sequence data.
We discussed:
- The team’s main objectives in creating the Cannabis Expression Atlas
- How our understanding of cannabis genomics compares to other commercial crops
- How gene expression data can advance plant breeding and genetic engineering
- Potential applications of the Cannabis Expression Atlas in commercial cannabis cultivation
- and more
Thanks to This Episode's Sponsor: Medicinal Genomics
Medicinal Genomics (MGC) uses its unmatched knowledge of the cannabis genome and the microbes affecting cannabis plants to create diverse testing solutions that improve crop yield, accelerate breeding programs, and ensure product safety. Growers and breeders use MGC’s cannabis genome sequencing services to identify novel traits, stabilize genetics, and protect intellectual property. Additionally, Kannapedia.net provides bioinformatics and blockchain certification for cultivar authenticity.
Learn more at medicinalgenomics.com
Additional Resources
Cannabis Expression Atlas: a comprehensive resource for integrative analysis of Cannabis sativa L. gene expression - www.biorxiv.org/content/10.1101/2024.09.27.615413v1
Cannabis Expression Atlas - cannatlas.venanciogroup.uenf.br
Register for CannMed 25 - cvent.me/emBPno
Meet the CannMed 25 Advisory Board - cannmedevents.com/speakers/
Submit Your Abstract for CannMed 25 - www.cvent.com/c/abstracts/b940a934-cb07-4c59-8fb2-5f06265945b5
Review the Podcast - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives/
Переглядів: 23

Відео

How Are People That Use Cannabis, Using it To Treat Their Symptoms? - Laura Barrett
Переглядів 17012 годин тому
Laura Barrett, MBA, BSN, RN, known as “Nurse Laura,” is the Founder and Executive Director of the National Clinical Director Consortium and the Owner and Operator of Ask Nurse Laura. She serves on the boards of several non-profits, including the Connor Sheffield Foundation. Nurse Laura is dedicated to educating individuals and groups about cannabis and psychedelic medicine options, whether in s...
Identifying Ratios & The Importance of Doing Your Own Research with Cannabis / Hemp Products
Переглядів 7914 годин тому
Laura Barrett, MBA, BSN, RN, known as “Nurse Laura,” is the Founder and Executive Director of the National Clinical Director Consortium and the Owner and Operator of Ask Nurse Laura. She serves on the boards of several non-profits, including the Connor Sheffield Foundation. Nurse Laura is dedicated to educating individuals and groups about cannabis and psychedelic medicine options, whether in s...
Analyzing Cannabis Gene Expression with Kevelin Barbosa-Xavier
Переглядів 53721 годину тому
Kevelin Barbosa-Xavier is a PhD student in Plant Biotechnology at Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) where she conducts research under the supervision of Thiago Motta Venancio. She is a computational biologist, investigating the genes and gene networks involved in plant secondary metabolic pathways and fiber production, specifically in the Cannabis sativa species. Ke...
Investigating Cannabinoids for PTSD Relief with Laura Barrett
Переглядів 30921 день тому
Laura Barrett, MBA, BSN, RN, known as “Nurse Laura,” is the Founder and Executive Director of the National Clinical Director Consortium and the Owner and Operator of Ask Nurse Laura. She serves on the boards of several non-profits, including the Connor Sheffield Foundation. Nurse Laura is dedicated to educating individuals and groups about cannabis and psychedelic medicine options, whether in s...
How Have Attitudes from Major Sports Organizations Changed When it Comes to Cannabis?
Переглядів 7028 днів тому
How Have Attitudes from Major Sports Organizations Changed When it Comes to Cannabis?
How Did You Get Started Researching Cannabinoids and Athletics? - Elizabeth Thompson
Переглядів 288Місяць тому
How Did You Get Started Researching Cannabinoids and Athletics? - Elizabeth Thompson
Cannabinoids for Athletics, Concussions, and Pain with Elizabeth Thompson
Переглядів 421Місяць тому
Cannabinoids for Athletics, Concussions, and Pain with Elizabeth Thompson
Is Abstinence from THC a Solution for CHS? - Megan Mbengue & Codi Peterson
Переглядів 158Місяць тому
Is Abstinence from THC a Solution for CHS? - Megan Mbengue & Codi Peterson
New Cannabinoid Hyperemesis Syndrome (CHS) Survey - Megan Mbengue & Codi Peterson
Переглядів 228Місяць тому
New Cannabinoid Hyperemesis Syndrome (CHS) Survey - Megan Mbengue & Codi Peterson
Surveying Cannabinoid Hyperemesis Syndrome Patients with Megan Mbengue and Codi Peterson
Переглядів 488Місяць тому
Surveying Cannabinoid Hyperemesis Syndrome Patients with Megan Mbengue and Codi Peterson
How Do You Create a Homozygous Strain?
Переглядів 255Місяць тому
How Do You Create a Homozygous Strain?
What Is The Process of Creating a New Strain? - Justin Esquivel
Переглядів 250Місяць тому
What Is The Process of Creating a New Strain? - Justin Esquivel
Breeding Techniques to Create Unique Genetics with Justin Esquivel
Переглядів 2,1 тис.2 місяці тому
Breeding Techniques to Create Unique Genetics with Justin Esquivel
Why has there been a lack of research into terpenes as a therapeutic? - John Streicher, PhD
Переглядів 2072 місяці тому
Why has there been a lack of research into terpenes as a therapeutic? - John Streicher, PhD
What are terpenes? What is their role in cannabis? - John Streicher, PhD
Переглядів 4022 місяці тому
What are terpenes? What is their role in cannabis? - John Streicher, PhD
Investigating Terpenes for Chronic Pain Management with John Stretcher, PhD
Переглядів 1,1 тис.2 місяці тому
Investigating Terpenes for Chronic Pain Management with John Stretcher, PhD
Potency Loss in Cannabis Infused Beverages
Переглядів 1502 місяці тому
Potency Loss in Cannabis Infused Beverages
Scalping Rates, Can Liners, & Bottling Explained
Переглядів 1122 місяці тому
Scalping Rates, Can Liners, & Bottling Explained
Preserving Cannabis Beverage Potency with Harold Han, PhD
Переглядів 4243 місяці тому
Preserving Cannabis Beverage Potency with Harold Han, PhD
Treating Restless Leg Syndrome with Cannabis with Debra Kimless, MD
Переглядів 7933 місяці тому
Treating Restless Leg Syndrome with Cannabis with Debra Kimless, MD
CannMed 25 Innovation & Investment Summit | June 17-20 - Río Grande, Puerto Rico
Переглядів 2893 місяці тому
CannMed 25 Innovation & Investment Summit | June 17-20 - Río Grande, Puerto Rico
Endotoxins in Cannabis Microbial Testing - Kevin McKernan
Переглядів 1,1 тис.3 місяці тому
Endotoxins in Cannabis Microbial Testing - Kevin McKernan
Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot - Ethan Russo, MD
Переглядів 1,7 тис.3 місяці тому
Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot - Ethan Russo, MD
Applying Machine Learning Tools to the ASD Cannabis‑Responsive™ Biomarker Database - Bonni Goldstein
Переглядів 4173 місяці тому
Applying Machine Learning Tools to the ASD Cannabis‑Responsive™ Biomarker Database - Bonni Goldstein
The Art and Science of Combining Cannabinoids for Treatment Success - Dustin Sulak, DO
Переглядів 5243 місяці тому
The Art and Science of Combining Cannabinoids for Treatment Success - Dustin Sulak, DO
Transmission, Spread, and Longevity of Hop Latent viroid affecting Cannabis - Zamir Punja, PhD
Переглядів 4383 місяці тому
Transmission, Spread, and Longevity of Hop Latent viroid affecting Cannabis - Zamir Punja, PhD
Endometriosis: A Clinical Endocannabinoid Deficiency Condition? - Genester Wilson-King, MD
Переглядів 1463 місяці тому
Endometriosis: A Clinical Endocannabinoid Deficiency Condition? - Genester Wilson-King, MD
Characterization of Less Studied Cannabis Phytochemicals - Tim Lefever
Переглядів 1903 місяці тому
Characterization of Less Studied Cannabis Phytochemicals - Tim Lefever
Effect of Cannflavins on Mitigating a Motor Neuron Disease - Akeem Gardner, LLB
Переглядів 1883 місяці тому
Effect of Cannflavins on Mitigating a Motor Neuron Disease - Akeem Gardner, LLB

КОМЕНТАРІ

  • @HawaiiLimey
    @HawaiiLimey 41 хвилина тому

    As someone who enjoys growing plants and follows permaculture practices I wonder what role that the intensive selective breeding of late plays into creating favourable conditions for gram negative bacteria proliferation. In the natural presentation of cannabis the flower would be more akin to that seen in other uncultivated plants whereas to massively increase the psychoactive cannibinoids todays plants are grown to have incredibly dense flowers concentrated with resin glands. This undoubtedly would prevent airflow and UV penetration. I'd imagine that maximizing nutritient uptake including sugars would yet further provide the necessary building blocks for gram negative bacterial proliferation.

  • @Steve-vr4zb
    @Steve-vr4zb 2 дні тому

    did you just explain how you transfer cancer to a cannibas plant? why would you ever wantg to do that?

  • @hashtastic3537
    @hashtastic3537 2 дні тому

    Its cuz the companies that own the facilities dont care, its a cash grab. Ive worked for a couple and they actively stopped me from producing better quality in favor of profit. I attempted to institute actual living organic soil in 1 facility but the overall harvest would have been 10% less than the salt nutes they were using at the time (jacks) and they outright refused to listen. I tried to argue that the quality of the product would more than merit a 10% increase in price for the customer but they actually said they didnt think the customer was worth the effort since their sales were fine how things were... then they told me to dial down the trimmer depth to increase leaf to bud ratio😑

  • @wruzzer
    @wruzzer 4 дні тому

    it's a lie.

  • @olliepriddey1161
    @olliepriddey1161 4 дні тому

    Could it be that the CHS is caused by sprayed cannabis more than medical?

  • @Mccloud4200
    @Mccloud4200 5 днів тому

    This is wonderful!

  • @karinavieira646
    @karinavieira646 8 днів тому

    Congratulation Kevelin 🎉 research very interesting

  • @brian420pm
    @brian420pm 8 днів тому

    So trichome building is rock solid and not easily swayed by chemotype level breeding... it'll be a tough nut to crack. Great content!🙏

  • @TheGangjahman
    @TheGangjahman 8 днів тому

    ~🔥~🍓👑🍓~🔥~

  • @johnVojtek.
    @johnVojtek. 9 днів тому

    Wow this was sooo amazing. Thank you so much for this presentation

  • @rosemalfabon7276
    @rosemalfabon7276 9 днів тому

    Great resources will definitely go check it out. Amazing work. Congratulations on your accomplishments ❤

  • @SomeonethatsNoOne
    @SomeonethatsNoOne 9 днів тому

    Good information, appreciate this drop!

  • @InfinityGamerHDx
    @InfinityGamerHDx 9 днів тому

    Thanks for sharing🔥

  • @Jordan_Makes
    @Jordan_Makes 9 днів тому

    This is the most in depth study I have seen on CHS. Thank you for doing this research. I hope we can come up with a cure one day. After watching this it seems like the cure might have something to do with gene therapy.

  • @rayathome151-i1n
    @rayathome151-i1n 9 днів тому

    Cool stuff. I'll have to rewatch it. Thank you for the content.

  • @superconscious.
    @superconscious. 9 днів тому

    Love academics 😎

  • @natel9019
    @natel9019 9 днів тому

    Feminised stock can almost negate up to half of the genome.

    • @InfinityGamerHDx
      @InfinityGamerHDx 9 днів тому

      Male chromosomes have way less information and are mostly about male sex organs

    • @natel9019
      @natel9019 9 днів тому

      @InfinityGamerHDx A few genes can completely change the overall expression of the plant. I am in on a few breeding projects that completely disagree with you. Males definitely contribute traits to its progeny.

    • @InfinityGamerHDx
      @InfinityGamerHDx 8 днів тому

      @@natel9019 males also got a X chromosome not just Y

    • @natel9019
      @natel9019 8 днів тому

      @@InfinityGamerHDx Definitely. We have just noticed that some of the traits we like were lost when we tried to get them in via females. A few specific characteristics have carried through the male lines, thus far on a few different strains so far. Cheers

  • @terencehunter4035
    @terencehunter4035 10 днів тому

    🏴🎩🏴

  • @grigoriofabrosi1638
    @grigoriofabrosi1638 10 днів тому

    It's worth mentioning that despite what lab tests tell us, different people reach different conclusions in their personal experience and preferences; whether they are right or wrong, their personal taste informs their opinions of what works. They can be both technically wrong and experientially right.

  • @BakedByBekah
    @BakedByBekah 10 днів тому

    Can you test me I’ve got videos of myself in the shower dying I’ve had multiple hospital visits. I didn’t believe it was the Chs & I finally realized maybe it’s actually the weed doing it.

  • @BakedByBekah
    @BakedByBekah 10 днів тому

    I’ve had episodes that are worse than labor without medication. I can’t even describe how bad my episodes get & if I don’t drink water just to puke it back up I’d honest have died from dehydration

  • @letstalkcannabiz9295
    @letstalkcannabiz9295 12 днів тому

    Enforcement underway....compliance and regulations being enforced...federal legalization underway

  • @Matooosh
    @Matooosh 12 днів тому

    Mark mentioned there is "his" book. I cannot find anything under his name, any advice?

  • @suzh4187
    @suzh4187 13 днів тому

    “Standard of Care” for cancer 😳doesn’t cure anything.

  • @aledee251
    @aledee251 15 днів тому

    I had CHS as the Doctor think and I was in the hospital for two days but after the 3 day I was back to myself

  • @cxvzf
    @cxvzf 15 днів тому

    Short Summary: - The speaker discusses cannabis product recalls, starting with an overview of learning objectives related to understanding recall variability, reasons for recalls, and specific contaminants involved. - A map illustrating cannabis testing regulations across different states is presented, highlighting states with testing rules for both medical and adult use. - 38 states have legalized cannabis programs, with 20 documenting recalls on their regulatory websites. - The presentation contrasts findings with FDA product recalls in the food and pharmaceutical industries, emphasizing the importance of safeguarding public health and ensuring consumer safety. - Recent examples of recalls, including food and pharmaceutical products affected by contamination, are provided. - The analysis examined 262 recalls across 20 states up to March 2024, identifying trends and states with the highest number of recalls, particularly Colorado, Washington, Michigan, and Oregon. - The discussion points out an increase in recalls from 2021 to 2023, with certain states accounting for over 90% of the rise. - The speaker highlights the lack of transparency in recall notices across different states, noting that specific contaminants are often not named in recalls. - Pesticide contamination accounted for nearly 40% of recalls, while microbial contamination made up almost 30%. - The segment concludes with a call for better regulatory practices and transparency in recall information to ensure consumer safety, suggesting collaboration with cannabis science institutions to enhance recall data quality.

  • @lyfandeth
    @lyfandeth 16 днів тому

    Recalls why?

  • @ikersok
    @ikersok 17 днів тому

    Hi, I heard about the VIROID problem a year ago. I've been thinking about it a lot and I've come up with an idea on how to fix it. Could someone help me? Thanks.

  • @domenicomonteleone3055
    @domenicomonteleone3055 17 днів тому

    The Yellowing of the leaves is it water or plant nutrients i follow you 💯 from 🇨🇦

    • @hashtastic3537
      @hashtastic3537 2 дні тому

      Its tobacco mosaic virus I think. If it is, this wasnt an extreme case. Usually it causes extreme mutations right after the yellowing stage and your stems flatten while widening. They also develop leaf clustering and a whirled shape. Very contagious too

  • @aworldofsound5701
    @aworldofsound5701 19 днів тому

    I am pretty sure the "greenhouse" farm he shows in this video is the inside of District Cannabis in Maryland. This is my favorite facility that i have ever seen, highly advanced and a star in the world of automation and efficiency. At their grow if you can have a reader for it to accurately track any level they have it. They are truly a star in their mindfulness and resourcefulness.

  • @speedy2426
    @speedy2426 19 днів тому

    don't forget the throwing up until you lose your voice.

  • @Badg0r
    @Badg0r 19 днів тому

    This dude looks and speaks like Chandler.

  • @juliabo6088
    @juliabo6088 19 днів тому

    do purple trichomes

  • @calebharbour2111
    @calebharbour2111 21 день тому

    Absolutely fantastic video! Thank you for making this freely available to us on UA-cam❤

  • @MachineYearning
    @MachineYearning 21 день тому

    For context, 4 possible nucleotides in RNA (AUCG) at 250 nucleotides in length, if expressed linearly, gives structural entropy of just under 500 bytes, or half of a kilobyte. Disclaimer, I am not a biologist. I would imagine there's something very interesting going on in how these RNA molecules behave when folding up into more complex structures. Would love to see the rest or the talk

  • @djackson006
    @djackson006 22 дні тому

    No rem sleep can’t be good long term… unless you want mad dreams when you stop.

  • @djackson006
    @djackson006 22 дні тому

    Which cannabinoids? Just THC?

  • @ToddBurrier-u7m
    @ToddBurrier-u7m 23 дні тому

    Laura is awesome.

  • @weissefabrik
    @weissefabrik 23 дні тому

    The comment on the boveda stuff was perfect. thank you for that ;)

  • @OlegMaryAces
    @OlegMaryAces 23 дні тому

    👏👏👏 Laura 🌱💪💗

  • @thegingerballbag
    @thegingerballbag 23 дні тому

    What about all of the illegal pesticides used discovered in recent indpendent tests of the majority of legal weed shops someting to consider?. i havnt heard any of these talks ever mention anything other than it has to be the plants problem and not a problem with big agro/farm or pharma especialy in america you are sold poison daily in your food and drinks never mind the legal drugs so before i think any of this is a problem somebody needs to check its not just another american business practice problem before they try to sell you another drug to fix the problem they created 😂😅😢

  • @ramones11ful
    @ramones11ful 24 дні тому

    Excellent video!! I do have a ? I use a trim bowl to trim leaves of the buds. It saves so much time its a miricle . I fear though im losing tricomes. So are they strong enough to survive a trim bowl . Thank you/

  • @Fa20Dit
    @Fa20Dit 25 днів тому

    Basically bruxism…less pain when biting, brain thinks you can bite harder….

  • @CannabisCarl
    @CannabisCarl 26 днів тому

    I enjoy this research, but most probably think it's boring

  • @vernaholladay9829
    @vernaholladay9829 27 днів тому

    My special needs adult son was on epidiolex to help with severe seizure’s, it helped so much. After 9 months he started projectile vomiting. He got to where the only thing he tolerated was boost, he lost 20 punds, he’s a thin guy to begin with. Epidiolex was stopped in the hospital. Eating his normal diet, but failing to put on weight, he’s considered failure to thrive adult. He’s mentally at a 9 month level mentally, he’s unable to tell us anything and he’s quadriplegic. He is 46 and we are so very worried about him. He’s severely affected with tuberous sclerosis complex.

  • @djackson006
    @djackson006 27 днів тому

    You need to provide links/receipts for the studies.

    • @medicinal.genomics
      @medicinal.genomics 24 дні тому

      The graph that is shown can be referenced here in figure 2 here: pubmed.ncbi.nlm.nih.gov/34874191/ In addition, the link to where this video starts can be found here: ua-cam.com/video/E3s5cAC8uO8/v-deo.htmlfeature=shared&t=845

  • @Buffywestfield
    @Buffywestfield 28 днів тому

    So interesting, thank you for sharing! I didn't know that aspergillus from smoking a joint could cause aspergilliosis due to a genetic disorder Can you share a link to the study? Can I be screened for this genetic disorder? Does it have a name? Thanks

  • @Breakzoras
    @Breakzoras 28 днів тому

    Crazy thing is that even if you show people this video they are still going to deny that cannabis is a medicine

  • @Frxxdxm
    @Frxxdxm 28 днів тому

    Wow thank you for this!

  • @catherinedamico4596
    @catherinedamico4596 28 днів тому

    What is this… lazy diagnosis

    • @wruzzer
      @wruzzer 4 дні тому

      exactly. "oh, smoke cannabis? it's the cannabis"