Hannah Went
Hannah Went
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Unlocking the Secrets of Healthy Aging
What does it take to live not just longer but healthier lives? In this week’s episode of the Everything Epigenetics podcast, Dr. Jamie Justice and I explore the groundbreaking research and initiatives shaping the future of healthy aging. From bridging the gap between lifespan and healthspan to revolutionary breakthroughs like the XPRIZE Healthspan prize, we dive deep into the science and innovations driving progress in geroscience.
You'll learn about:
- What “healthy aging” truly means and why it’s vital for everyone.
- How the gap between lifespan and healthspan impacts society and what can be done to close it.
- The critical factors influencing long-term healthspan and actionable steps individuals can take.
- The goals and potential of the XPRIZE Healthspan initiative and the exciting innovations emerging from it.
- How targeted initiatives like the SOLVE FSHD Bonus Prize could shape the future of disease-specific health research.
- A look ahead: breakthroughs and milestones expected in the next 5-10 years in aging research.
Chapters:
00:00 Welcome and Introduction
02:30 What “healthy aging” means to Dr. Jamie Justice
07:15 Lifespan vs. Healthspan: Bridging the gap
15:40 Key factors influencing long-term healthspan
22:10 Overview of the XPRIZE Healthspan Prize
28:45 Promising innovations from XPRIZE participants
35:20 The SOLVE FSHD Bonus Prize and its impact
42:10 Future breakthroughs in geroscience and aging research
49:30 Where to connect with Dr. Jamie Justice
Where to Find Us:
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Visit our website for more information and resources: everythingepigenetics.com
Переглядів: 32

Відео

Epigenetics and Canine Longevity: Unlocking Healthier, Longer Lives for Dogs
Переглядів 7714 днів тому
In this week’s episode of the Everything Epigenetics podcast, Dr. Christopher Minteer, Nicholas Minteer, and I dive into the fascinating intersection of canine health, longevity, and epigenetics. We explore how their company, Woofgenix, is revolutionizing the field through cutting-edge research and innovative products that aim to extend the lifespan and healthspan of our beloved pets. From unde...
Epigenetic Hacks for Longevity: Strategies to Thrive at 62
Переглядів 1,1 тис.28 днів тому
In this episode of Everything Epigenetics, host Hannah Went sits down with Dave Pascoe, a retired network security architect who’s redefining the way we think about aging. Despite being 62, Dave has been able to have a lower "biological age" and slow pace of aging, a testament to his dedication to health optimization, epigenetics, and biological tuning. Known for ranking among the top contender...
From Aging to Cancer Risk in Epigenetics with Dr. Chiara Herzog
Переглядів 120Місяць тому
In this week's episode of the Everything Epigenetics podcast, Dr. Chiara Herzog and I talk about how epigenetics is making waves in the medical world and how it could change treatment. Translational scientist and research fellow Dr. Herzog provides insights from her role in the Biomarkers of Aging Consortium and her work on the TirolGESUND project, one of the largest multi-omic human lifestyle ...
Epigenetic Aging in Mood Disorders: Exploring the Role of Lithium and Future Therapies
Переглядів 190Місяць тому
In this week’s episode of the Everything Epigenetics podcast, Dr. Gabriel Fries and I discuss the fascinating intersections of epigenetics, aging, and psychiatric disorders. Dr. Fries, an Assistant Professor in Psychiatry and Behavioral Sciences at UTHealth, shares his groundbreaking research on the molecular underpinnings of mood disorders such as bipolar disorder and suicide risk. We dive int...
Detecting the Undetectable: Epigenetics in Early Cancer Detection with Dr. Joshua Routh
Переглядів 2082 місяці тому
Recent research from the University of Chicago shows that only 14% of cancers in the U.S. are diagnosed after the patient had a recommended screening test. 57% of diagnosed cancers do not have screening tests and account for 70% of all cancer-related deaths. 86% of cancer cases still go undiagnosed after recommended screenings. ‍16M life years saved in the U.S. from early-detection screenings. ...
The Future of Kidney Health: How Dr. Charles Breeze Is Changing the Game with Epigenetics
Переглядів 2882 місяці тому
In this week’s episode of the Everything Epigenetics podcast, I’m joined by Dr. Charles Breeze, an expert in computational epigenetics. We talk about his inspiring journey into the field of epigenetics, his trailblazing research on kidney function across diverse ethnic groups, and the innovative tools he's developed to push the boundaries of epigenetic research. Dr. Breeze shares how his fascin...
Alzheimer’s Disease as an Epigenetic Disease with Dr. David Katz
Переглядів 3993 місяці тому
Alzheimer’s disease is a devastating neurodegenerative condition that slowly erodes memory, cognitive function, and the ability to perform even the simplest tasks. It’s heartbreaking not only for those diagnosed but also for their loved ones as they watch a gradual loss of the person they knew. This is exactly how I felt in 2015 when I watched my grandmother be taken by this awful disease. The ...
The Power of Single-Cell Epigenetic Profiling
Переглядів 1573 місяці тому
In this week’s episode of the Everything Epigenetics podcast, Dr. Hannah Went sits down with Alex Trapp, a computational biologist deeply involved in aging research. The two explore the cutting-edge development of single-cell epigenetic clocks and their potential applications in the field of longevity science. Alex shares his journey from experimental biology to computational approaches and dis...
Development and Application of Epigenetic Predictors with Dr. Varun Dwaraka
Переглядів 1514 місяці тому
The development and application of epigenetic predictors of health is revolutionizing the way we understand and approach personalized medicine. These predictors, derived from analyzing DNA methylation patterns, provide a powerful tool for assessing biological age, disease risk, and overall health. By leveraging advanced machine learning and AI, researchers can identify specific epigenetic marke...
Unraveling the Complexity of Epigenetics in the Brain with Dr. Esther Walton
Переглядів 2664 місяці тому
In Europe, people aged 65 typically spend about half of their remaining years managing disabilities. Much of the existing research on aging has predominantly focused on identifying "cures" rather than exploring strategies for healthy aging. Dr. Esther Walton’s is breaking new frontiers with the unconventional approach that aging begins at birth and should be approached through a comprehensive l...
Epigenetic Regulation of Immunity with Dr. Andrew DiNardo
Переглядів 1845 місяців тому
The immune system adapts to various threats through innate and adaptive responses, utilizing epigenetic mechanisms to regulate gene activity without changing DNA sequences. These mechanisms help maintain long-term immune phenotypes, allowing the immune system to respond to changing environments. In innate immunity, epigenetic changes enable immediate pathogen responses, while in adaptive immuni...
Trauma's Epigenetic Impact on Mental Disorders with Dr. Janitza Montalvo-Ortiz
Переглядів 885 місяців тому
In this week’s episode of Everything Epigenetics, I am joined by Dr. Janitza Montalvo-Ortiz, Assistant Professor of Psychiatry at Yale University, who shares her journey into the world of epigenetics and psychiatry. Dr. Montalvo-Ortiz explains the pivotal role of epigenetics in understanding the genetic and environmental factors contributing to psychiatric disorders and emphasizes the importanc...
A therapeutic trip: From experience to epigenome with Dr. Candace Lewis
Переглядів 975 місяців тому
We are entering a new phase of understanding how our social environments affect our biology, particularly how they influence the genes involved in brain development and function. This knowledge helps us see how experiences like stress, trauma, and isolation can cause changes at the molecular level that may increase the risk of mental disorders. On the other hand, we're also exploring how positi...
Personalized Nutrition and Epigenetics with Dr. Lucia Aronica
Переглядів 2596 місяців тому
Personalized nutrition tailors dietary recommendations to an individual's unique biological needs, factoring in genetics, lifestyle, and health conditions to optimize health, prevent disease, and maintain overall well-being. Central to this approach is the role of epigenetics, which studies changes in gene expression that do not involve alterations to the DNA sequence but can be influenced by e...
Epigenetic Gestational Age Prediction with Kristine Løkås Haftorn
Переглядів 1189 місяців тому
Epigenetic Gestational Age Prediction with Kristine Løkås Haftorn
Causal Epigenetic Age Uncouples Damage and Adaptation with Kejun (Albert) Ying
Переглядів 37910 місяців тому
Causal Epigenetic Age Uncouples Damage and Adaptation with Kejun (Albert) Ying
The Importance of the Imprintome with Dr. Randy Jirtle
Переглядів 33810 місяців тому
The Importance of the Imprintome with Dr. Randy Jirtle
Integrating Epigenetics into the Social Models of Heath Disparities with Dr. Lauren Schmitz
Переглядів 17911 місяців тому
Integrating Epigenetics into the Social Models of Heath Disparities with Dr. Lauren Schmitz
Prioritizing Your Health Investment with Dr. Jeoff Drobot
Переглядів 19411 місяців тому
Prioritizing Your Health Investment with Dr. Jeoff Drobot
Unlocking the Epigenome from a Single Drop of Blood with Dr. Toinét Cronjé
Переглядів 108Рік тому
Unlocking the Epigenome from a Single Drop of Blood with Dr. Toinét Cronjé
Tracking and Measuring Biomarkers to Maximize Longevity with Dr. Michael Lustgarten
Переглядів 1,6 тис.Рік тому
Tracking and Measuring Biomarkers to Maximize Longevity with Dr. Michael Lustgarten
Methylation Risk Scores with Dr. Michael Thompson
Переглядів 258Рік тому
Methylation Risk Scores with Dr. Michael Thompson
The Role of Epigenetics in Functional Medicine with Dr. Jeffrey Bland
Переглядів 1,2 тис.Рік тому
The Role of Epigenetics in Functional Medicine with Dr. Jeffrey Bland
Assessing the Reproducibility and Integrity of DNA Methylation with Dr. Karen Sugden
Переглядів 149Рік тому
Assessing the Reproducibility and Integrity of DNA Methylation with Dr. Karen Sugden
MOSAIC: Multi-Organ Scores of Aging across Integrated Components with Raghav Sehgal
Переглядів 204Рік тому
MOSAIC: Multi-Organ Scores of Aging across Integrated Components with Raghav Sehgal
Personalized Biomarkers to Predict Surgery Outcomes with Dr. Christopher Ames
Переглядів 258Рік тому
Personalized Biomarkers to Predict Surgery Outcomes with Dr. Christopher Ames
Reduce Your Biological Age in Just 8-Weeks with Dr. Kara Fitzgerald
Переглядів 4,3 тис.Рік тому
Reduce Your Biological Age in Just 8-Weeks with Dr. Kara Fitzgerald
A Deeper Dive into DunedinPACE with Dr. Daniel Belsky
Переглядів 848Рік тому
A Deeper Dive into DunedinPACE with Dr. Daniel Belsky
How Fit Are You According to Your DNA? With Kristen McGreevy
Переглядів 108Рік тому
How Fit Are You According to Your DNA? With Kristen McGreevy