- 81
- 226 755
Machine Medicine Technologies
United Kingdom
Приєднався 21 лип 2017
We are a small team based in London, that develops a platform to help assess people with Parkinson’s disease better.
Motor assessment in Parkinson’s disease is plagued by issues of subjectivity and reproducibility - not to mention systematic biases such as rater drift. To counter this, we are developing a platform, called Kelvin, that can be used from any device (e.g. smartphones or tablets). Named after the famous physicist so beloved of precise measurement, the platform allows researchers to record, score, store and analyse video of Parkinson’s patients during motor assessment.
Once captured and organised, the platform uses a cutting-edge computer vision technique, called pose estimation, to objectively track the movement of the patients down to the fingertip level and deliver objective metrics of core symptoms, such as tremor and bradykinesia.
Motor assessment in Parkinson’s disease is plagued by issues of subjectivity and reproducibility - not to mention systematic biases such as rater drift. To counter this, we are developing a platform, called Kelvin, that can be used from any device (e.g. smartphones or tablets). Named after the famous physicist so beloved of precise measurement, the platform allows researchers to record, score, store and analyse video of Parkinson’s patients during motor assessment.
Once captured and organised, the platform uses a cutting-edge computer vision technique, called pose estimation, to objectively track the movement of the patients down to the fingertip level and deliver objective metrics of core symptoms, such as tremor and bradykinesia.
Effects of DBS on sleep in patients with major depressive disorder.
Dr. Joram van Rheede is a Senior Postdoctoral Neuroengineer in the Bioelectronics Lab at the Institute of Biomedical Engineering and the MRC Brain Network Dynamics Unit, University of Oxford. His current research focuses on the interaction between sleep/wake cycles, circadian rhythms, and neurological conditions using data from patients with brain stimulation devices.
Deep brain stimulation (DBS) is a therapy proven to be effective for the management of symptoms of movement disorders such as epilepsy, and is under investigation for other conditions including chronic pain, depression, and obsessive-compulsive disorder. DBS therapy settings are generally set during the clinician working day, and then applied 24/7. But how does DBS interact with sleep and circadian rhythms? Using long-term brain activity recordings from implanted DBS devices in patients with major depressive disorder, as well as examples from Parkinson’s disease and epilepsy, Dr. Van Rheede will illustrate the need for DBS to take sleep into account.
Joram will also report on progress made in the Oxford Translational Bioelectronics lab towards a sleep-aware DBS device. As DBS continues to be a critical therapy in neurological conditions, understanding its interaction with sleep and circadian rhythms is essential for optimizing treatment outcomes and developing more effective, sleep-aware DBS devices.
Deep brain stimulation (DBS) is a therapy proven to be effective for the management of symptoms of movement disorders such as epilepsy, and is under investigation for other conditions including chronic pain, depression, and obsessive-compulsive disorder. DBS therapy settings are generally set during the clinician working day, and then applied 24/7. But how does DBS interact with sleep and circadian rhythms? Using long-term brain activity recordings from implanted DBS devices in patients with major depressive disorder, as well as examples from Parkinson’s disease and epilepsy, Dr. Van Rheede will illustrate the need for DBS to take sleep into account.
Joram will also report on progress made in the Oxford Translational Bioelectronics lab towards a sleep-aware DBS device. As DBS continues to be a critical therapy in neurological conditions, understanding its interaction with sleep and circadian rhythms is essential for optimizing treatment outcomes and developing more effective, sleep-aware DBS devices.
Переглядів: 290
Відео
Brainwaves to Breakthroughs: Navigating EEG's Data Analysis in Cognitive and Medical Fields
Переглядів 814 місяці тому
Dr Conor Houghton is an associate professor in Computer Science and reader in mathematical neuroscience at the University of Bristol. He is principally focused on mathematical and computational approaches to neuroscience, particularly on models of mood and movement and on computational approaches to neurolinguistics. Electroencephalography (EEG) is a convenient approach to measuring neural acti...
MMT Toe Tap Pipeline Demo
Переглядів 804 місяці тому
An illustration of how a raw video of a patient performing a given activity (toe tapping) is analysed and given an inferred clinical score/rating, with 0 human interventions.
Patient out Reach 3 0
Переглядів 8311 місяців тому
Discover the latest enhancements to our patient-centric mobile app, Reach (RElational, Asynchronous, Clinical, Hub). We've taken a giant leap forward by integrating cutting-edge generative AI capabilities-both visual and linguistic. Meet Kelvin, your AI-powered companion residing in Reach! We asked Kelvin to give you a firsthand account of the incredible benefits he brings to you, and the resul...
Safe and effective AI-powered medical devices
Переглядів 145Рік тому
Yuriy Dushin, Lead of the Data Science team at Machine Medicine, delves into the world of developing cutting-edge computer vision algorithms for neurological motor diseases. His expertise extends to designing clinical and analytical validation studies for innovative computer vision devices. During the insightful meetup, Yuriy shared his wealth of practical experience and expertise, focusing on ...
Why the brain uses spikes (and what that means for brain disorders)?
Переглядів 222Рік тому
Professor Mark Humphries is a Chair in Computational Neuroscience in the University of Nottingham. With decades of dedicated research in the area, Professor Humphries speaks about the complexities of the human brain, specifically focusing on the fascinating topic, "Why the brain uses spikes and what that means for brain disorders." The human brain, a marvel of nature, relies on billions of neur...
MACHINE MEDICINE - Cedars Sinai Accelerator 2023
Переглядів 187Рік тому
A pitch video explaining what Machine Medicine does and why.
June 2023 Computational Medicine London Meetup
Переглядів 93Рік тому
Computational Medicine is a combination of computer science and medicine. It is all about using technology and building models to help doctors and researchers to solve leading medical problems. During the event, the participants had a chance to hear from experts in the field and network with speakers and other attendees. Our next event will take place on Wed, August 23 2023, at 6 pm. The addres...
Computational Medicine Meetup: Computer Vision-based Motor Assessments by Jonathan O’Keeffe
Переглядів 171Рік тому
Computational medicine is a combination of computer science and medicine. It is all about using technology and building models to help doctors and researchers to solve leading medical problems. Currently, doctors assess patients’ movements in a “low-tech” way by interacting with them and another person records the results. But is there a more data-driven and scalable approach to assess these mo...
Computational Medicine Meetup: Towards a Theory of Brain Computer Interface by Dimitris Pinotsis
Переглядів 207Рік тому
Computational Medicine is a combination of computer science and medicine. It is all about using technology and building models to help doctors and researchers to solve leading medical problems. Expert computational neuroscientist, Dimitris Pinotsis, talks about the theory towards Brain-Computer Interface (BCI). BCI devices allow us to interact with machines using just our thoughts; well-known e...
Machine Medicine Explainer
Переглядів 1,8 тис.Рік тому
A video explaining how Machine Medicine is building the software and data layer for delivering bioelectric medicine to hundreds of millions of patients with debilitating neurological and other diseases.
Multi-Item Activity Recognition on KELVIN
Переглядів 2222 роки тому
Multi-Item Activity Recognition on KELVIN
Video & Audio Quality Control in the KELVIN-CLINIC app
Переглядів 842 роки тому
Video & Audio Quality Control in the KELVIN-CLINIC app
KELVIN-REACH Demo | Parkinson's Disease Motor Assessment Tool at Home
Переглядів 3522 роки тому
KELVIN-REACH Demo | Parkinson's Disease Motor Assessment Tool at Home
A Computer-Vision Based Method for Quantifying Parkinsonian Gait
Переглядів 2572 роки тому
A Computer-Vision Based Method for Quantifying Parkinsonian Gait
Maximising UPDRS information while minimising assessment time
Переглядів 1452 роки тому
Maximising UPDRS information while minimising assessment time
KELVIN-PD Demo | Parkinson's Disease Motor Assessment Tool
Переглядів 1,1 тис.3 роки тому
KELVIN-PD Demo | Parkinson's Disease Motor Assessment Tool
Rigidity assessment in the KELVIN CLINIC app
Переглядів 1,4 тис.4 роки тому
Rigidity assessment in the KELVIN CLINIC app
Dr Jonathan O'Keeffe & Dr Fiona Pathiraja at the Royal Society of Medicine
Переглядів 2614 роки тому
Dr Jonathan O'Keeffe & Dr Fiona Pathiraja at the Royal Society of Medicine
Huntington's Disease chorea - automatic analysis
Переглядів 49 тис.6 років тому
Huntington's Disease chorea - automatic analysis
Give her homoeopathic medicine - 1) Mygale lasiodora 30 2) Terantula hispania 30 She will be fine & completely cured.
How you're secure of this ?
Amazing work ! Should be very useful clinically!
I sleep better when I'm able to do some meditation before bed, not easy though. I like using that mindfulness book called 30 Days to Stop Obsessing by Harper Daniels.
Where it is?
Great things Dr Madida on UA-cam has being doing for mankind, I undergo his Parkinson disease treatment plan for weeks and my Parkinson Disease was completely reversed..
That some sick dance moves
Are you joking
u know what's sick? laughing about other peoples diseases
Hello Sam Can You Provide me the Source code and Data Set of this
Can i get your Complete project for further research
Its really sad.
Is better to wear hijab
What your comment has to do with the video ?
Can someone tell me if I have Parkinson’s? I just did this test, and my right hand was terrible I didn’t last very long and i was only able to do small movements with my right hand as compared to my left hand.. I’m 22 with essential tremor and my grandmother had Parkinson’s disease
Please see a neurologist for an accurate diagnosis
I saw two board-certified neurologists: One told me I didn’t have Parkinson’s. The other told me I definitely did. And I have a witness and the after-visit reports to prove this is true.
I don’t think you can find out if you have Parkinson’s in the comments section of a UA-cam video.
@@FlaschDJ thank you for your honesty, I do appreciate that. I’m going to see a physio for my stooping back, and then hopefully see a doctor later this year to see if they can help with a formal diagnosis.
@@brandonhealy7158 Good. Keep moving.
Would a manipulated memory be as forensically genuine as the original record of that same memorable instance?
Ngl it took me awhile to mimic your hand.
In Hutchison s clinical methods it's said to test both arms together
As a sufferer with Essential Tremor, I found this video absolutely worthless. You may have longer videos that are helpful, but this short was not.
I (68) was recently diagnosed with ET. My symptoms are pretty mild. How are yours?
@@pwk22 Greetings Friend. I was diagnosed around 1997 when I was 47. My Mother had it as well, but it was never diagnosed. She was able to keep her handwriting and most of her ability to do small tasks up until shortly before her death. It annoyed her greatly. To be continued...
@@pwk22 In my case, I started noticing it in my teenage years when I attempted to take up Calligraphy. Over the years I have steadily lost ability. I type now with both thumbs, fingers anchoring both hands on the keyboard. I have also lost all ability to write and draw. It has not helped that I tripped and fell in October, breaking both wrists. I am mostly recovered from that, but the tremor marches on. To be continued...
@@pwk22 Drugs have not helped, and I think that the next step is a brain implant of some sort. I am studying my options. Please keep in mind that everyone is unique. My experience was not my Mother’s, and my experience isn’t yours. I am 71. I pray that you will stay at the level you are, and that medicines WILL help.
@@marymurphy2605 My cursive writing is poor. I have a bad time using a fork. I'm pretty nornal otherwise.
Is closed loop considered tonic stimulation?
Great interview, although talked not much about dbs and pain itself..
Proud of my countryman! 👍🏻✌🏻🧿
this guy needs to look up and apply reverse apoptosis to his research
Cool
what this color any app
քʀօʍօֆʍ 👉
If you’re considering getting a spinal cord stimulator implanted, please read this: “Implanted Spinal Cord Stimulators for Pain Relief: Illustrating the FDA’s Dangerously Lax Oversight of High-Risk Implantable Medical Devices” Public Citizen, June 2020 Michael A. Carome, M.D. You have a right to make an informed decision based on ALL the available evidence, not just the manufacturer-funded studies. You should know that your physician may be receiving compensation from those manufacturers. You have a right to ask and to receive an honest answer. A. The procedure is NOT minimally invasive, no matter what they say,. B. The devices are junk that burn, shock, and produce very serious infections and rejections from body. From 2004-2019 almost 1,000 people have died from associated effects of spinal cord stimulator surgery. C. Hundreds of people are paraplegic because the leads are placed in the extremely delicate epidural space; and while surgical techniques are improving, the surgeons haven’t figured out exactly why some people are still made paraplegic by the device and the surgery. D. Almost half of participants need re-operation from “lead migration”, shifting leads and dural puncture. Make sure you know the risks.
I am worn out just watching her.
Thank you this is such a horrific disease 🌹
なんの色？？
red
They're trying to replace physicians with AI machines!
Ye threpy aam logo tak kb Portchester gi
Ye konsi therpy hai please tell us
I want to recommend to you all about this traditional herbal doctor Ehimare on UA-cam that reverse my husband from Parkinson's disease and we have also see different amazing testimony about this doctor that encourage me and my husband to contact this herbal medicine doctor. You can also contact the Dr via email address:drehimareherbalremedyhome22@gmail.com or whatsap number +2349027349748...
Is it a positive result, which hand? Ty.
His left hand has a problem. Looks like mine, newly diagnosed with Parkinson’s.
Ye konsi therapy, hai batao na please
@@pastorpresent1 hi
Il est possible de guéri totalement l'autisme en 8 jour au maximum pour plus d'information le parkinson en 5 jour contactez nous au +221771807677
There is no cure
Thanks to Dr . OLUTA for his good work I never believe that HIV has cure, I was HIV positive over 3 year now before I came across a comment about how Dr. OLUTA cure HIV and herpes disease but when I saw it i have it in mind that he cant cure HIV I just decided to give it a try I contact him that night luckily to me he replied me, and i hold on to see the work of Dr. OLUTA if he is saying the truth he ask for some details about me i gave him all he needed and I waited to see his reply to my problem after all, he told me to go for check up and I went for HIV test I cant believe I was negative,am so happy and grateful to God for using Dr.OLUTA to cure me, that is the reason why i decided to write this wonderful testimony of our i was cured, i recommendDr. OLUTA to you all around the world,contact him on his you can also reach him through WhatsApp number+2349065326267Dr. OLUTA for helping me at this young age if you need help contact via email: (dr.olutaspellcaster@gmail. com}.m.facebook.com/pages/category/Product-Service/Drolutaherbalhome-100710878112591/
If you'd like to dig deeper into openEHR here's the UA-cam channel: ua-cam.com/channels/0rSnWtVmuvr4MJ4vHC_kQA.html
Great talk Aman and Jonathan, I really enjoyed it!
sir i appreciate your work could you please help us
Hi, is video captured by a regular video camera? Is there a demo for trial available?