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TruDiagnostic
United States
Приєднався 11 січ 2020
TruDiagnostic is a Health Data company, specializing in epigenetic testing & research.
We offer TruAge - a service that analyzes your personal patterns of DNA Methylation (a type of biomarker that can control gene regulation) to give an objective measure of biological aging, the risks associated with accelerated aging, and suggestions on how to turn back the clock.
Aging itself is the gradual loss of cell function, so accelerated aging is the #1 risk factor for many chronic diseases.
We believe DNA Methylation holds the key to analyzing those risk factors, and accurately tracking your personal progress, and the effectiveness of treatments as you work to manage aging.
--
TruDiagnostic is involved in a host of clinical trials, offer research-related lab services at our private CLIA-Certified lab, and partner with several academic research institutions to further develop the fields of epigenetics and longevity-focused personalized medicine.
Visit: trudiagnostic.com/truage
We offer TruAge - a service that analyzes your personal patterns of DNA Methylation (a type of biomarker that can control gene regulation) to give an objective measure of biological aging, the risks associated with accelerated aging, and suggestions on how to turn back the clock.
Aging itself is the gradual loss of cell function, so accelerated aging is the #1 risk factor for many chronic diseases.
We believe DNA Methylation holds the key to analyzing those risk factors, and accurately tracking your personal progress, and the effectiveness of treatments as you work to manage aging.
--
TruDiagnostic is involved in a host of clinical trials, offer research-related lab services at our private CLIA-Certified lab, and partner with several academic research institutions to further develop the fields of epigenetics and longevity-focused personalized medicine.
Visit: trudiagnostic.com/truage
The Truth About Biological Age Tests: Dr. Matt Dawson Reveals the Latest Insights
Learn what @PeterAttiaMD got wrong about biological age testing and epigenetics on the recent @hubermanlab podcast episode from our CEO, Dr. Matt Dawson.
🧬 𝗪𝗵𝗮𝘁 𝘄𝗲 𝗱𝗶𝘀𝗰𝘂𝘀𝘀:
- The importance of precision and evidence in biological age tests.
- How to differentiate between helpful vs. meaningless biological age tests.
- The evolution of biological age tests and how they have improved over time.
- The role of precision and predictive power in measuring chronic disease risk and life expectancy.
- How actuarial and advanced scientific lifespan tests compare to chronological age-based predictions.
- The reliability of various biological age tests and the credibility of their results.
- The potential of epigenetic clocks and the DunedinPACE algorithm for evaluating individual aging rates and informing clinical interventions.
The @hubermanlab episode with @PeterAttiaMD
ua-cam.com/video/79p1X_7rAMo/v-deo.html
👉 𝗢𝗨𝗥 𝗧𝗥𝗨𝗔𝗚𝗘 𝗕𝗜𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗔𝗚𝗘 𝗧𝗘𝗦𝗧
shop.trudiagnostic.com/products/truage-complete-epigenetic-collection
🍿 𝗪𝗔𝗧𝗖𝗛 𝗡𝗘𝗫𝗧
• 𝟴 𝗥𝗲𝗹𝗶𝗮𝗯𝗹𝗲 𝗪𝗮𝘆𝘀 𝗧𝗼 𝗜𝗺𝗽𝗿𝗼𝘃𝗲 𝗘𝗽𝗶𝗴𝗲𝗻𝗲𝘁𝗶𝗰 𝗔𝗴𝗶𝗻𝗴 - ua-cam.com/video/atAuDaNYmwc/v-deo.html
• 𝗘𝗳𝗳𝗲𝗰𝘁𝘀 𝗼𝗳 𝘁𝗼𝗯𝗮𝗰𝗰𝗼, 𝗮𝗹𝗰𝗼𝗵𝗼𝗹, 𝗮𝗻𝗱 𝗺𝗮𝗿𝗶𝗷𝘂𝗮𝗻𝗮 𝗼𝗻 𝗗𝗡𝗔 𝗺𝗲𝘁𝗵𝘆𝗹𝗮𝘁𝗶𝗼𝗻 -
ua-cam.com/video/GuoB_jJcf4k/v-deo.html
• 𝗡𝘂𝘁𝗿𝗶𝘁𝗶𝗼𝗻𝗮𝗹 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝗰𝗲 𝗮𝗻𝗱 𝗟𝗼𝗻𝗴𝗲𝘃𝗶𝘁𝘆 𝗱𝗶𝘀𝗰𝘂𝘀𝘀𝗲𝗱 -
ua-cam.com/video/Mk7QP7ENATc/v-deo.html
🔗 𝗦𝗢𝗖𝗜𝗔𝗟𝗦 + 𝗪𝗘𝗕𝗦𝗜𝗧𝗘
📸 Instagram - / trudiagnosticofficial
📱Facebook - / TruDiagnostic
🐦Twitter - / TruDiagnostic
🧪Website - www.trudiagnostic.com
🧬 𝗪𝗵𝗮𝘁 𝘄𝗲 𝗱𝗶𝘀𝗰𝘂𝘀𝘀:
- The importance of precision and evidence in biological age tests.
- How to differentiate between helpful vs. meaningless biological age tests.
- The evolution of biological age tests and how they have improved over time.
- The role of precision and predictive power in measuring chronic disease risk and life expectancy.
- How actuarial and advanced scientific lifespan tests compare to chronological age-based predictions.
- The reliability of various biological age tests and the credibility of their results.
- The potential of epigenetic clocks and the DunedinPACE algorithm for evaluating individual aging rates and informing clinical interventions.
The @hubermanlab episode with @PeterAttiaMD
ua-cam.com/video/79p1X_7rAMo/v-deo.html
👉 𝗢𝗨𝗥 𝗧𝗥𝗨𝗔𝗚𝗘 𝗕𝗜𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗔𝗚𝗘 𝗧𝗘𝗦𝗧
shop.trudiagnostic.com/products/truage-complete-epigenetic-collection
🍿 𝗪𝗔𝗧𝗖𝗛 𝗡𝗘𝗫𝗧
• 𝟴 𝗥𝗲𝗹𝗶𝗮𝗯𝗹𝗲 𝗪𝗮𝘆𝘀 𝗧𝗼 𝗜𝗺𝗽𝗿𝗼𝘃𝗲 𝗘𝗽𝗶𝗴𝗲𝗻𝗲𝘁𝗶𝗰 𝗔𝗴𝗶𝗻𝗴 - ua-cam.com/video/atAuDaNYmwc/v-deo.html
• 𝗘𝗳𝗳𝗲𝗰𝘁𝘀 𝗼𝗳 𝘁𝗼𝗯𝗮𝗰𝗰𝗼, 𝗮𝗹𝗰𝗼𝗵𝗼𝗹, 𝗮𝗻𝗱 𝗺𝗮𝗿𝗶𝗷𝘂𝗮𝗻𝗮 𝗼𝗻 𝗗𝗡𝗔 𝗺𝗲𝘁𝗵𝘆𝗹𝗮𝘁𝗶𝗼𝗻 -
ua-cam.com/video/GuoB_jJcf4k/v-deo.html
• 𝗡𝘂𝘁𝗿𝗶𝘁𝗶𝗼𝗻𝗮𝗹 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝗰𝗲 𝗮𝗻𝗱 𝗟𝗼𝗻𝗴𝗲𝘃𝗶𝘁𝘆 𝗱𝗶𝘀𝗰𝘂𝘀𝘀𝗲𝗱 -
ua-cam.com/video/Mk7QP7ENATc/v-deo.html
🔗 𝗦𝗢𝗖𝗜𝗔𝗟𝗦 + 𝗪𝗘𝗕𝗦𝗜𝗧𝗘
📸 Instagram - / trudiagnosticofficial
📱Facebook - / TruDiagnostic
🐦Twitter - / TruDiagnostic
🧪Website - www.trudiagnostic.com
Переглядів: 720
Відео
Applications of Epigenetic Aging Clocks & Methylation Risk using Whole Genome Methylation Profiling
Переглядів 380Місяць тому
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NEW Report Alert: Organ system clock developed with Yale
Переглядів 1 тис.2 місяці тому
Marking a milestone development in epigenetic research and clinical health applications, laboratory TruDiagnostic is launching the first ever, epigenetic aging analysis of individual organ systems, using validated and system-specific trained clocks. These algorithms, developed by scientists at Yale University, were previously released in biology journal bioRxiv as a preprint, with peer reviewed...
Understanding How to Interpret Your OMICm Age Report
Переглядів 2,5 тис.9 місяців тому
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OMICm Age Pre Launch Party with TruDiagnostic Researchers 1
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OMICm Age Introduction
Переглядів 2,4 тис.Рік тому
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Learn More About TruDiagnostic
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TRU D 45 PROMO
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How to Collect A Sample
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Intro To Epigenetic Methylation & Aging 8 18 21
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8 Reliable Ways To Improve Epigenetic Aging - TruDiagnostic
Переглядів 2,7 тис.Рік тому
Follow along on the slideshow: docs.google.com/presentation/d/1DEzpbL-ZzIRfoVnkwdzgeeaL05Do9JwYlRN_1JYKfTw/edit?usp=sharing Read the interventional Trials summary: drive.google.com/file/d/1-7oeGkq3uqhZtKAejPXiQ23dMDzUVjO5/view?usp=sharing Follow us: Facebook: TruDiagnostic Instagram: trudiagnosticofficial Pinterest: www.pinterest.com/trudiagnostic/ Twitter: twitter.c...
Report Interpretation Guide Part 2 Additional Health Reports - TruDiagnostic
Переглядів 722Рік тому
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DIFFERENT WAYS TO MEASURE BIOLOGICAL AGING 1 23 23- TruDiagnostic
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New Inflammation & Physical Performance Reports: Coming Spring 2023 to our Complete Collection Kits
Переглядів 575Рік тому
More data, same price. You read that right! Join us for an exclusive, sneak-peak at the new data reports that will soon be included in our TruAge Complete Collection. In this webinar, we go over what's being added this Spring 2023 and how you can incorporate these new metrics into your patient care. The new reports we will launch (for no cost) will be predictors of physical performance includin...
Updated Literature Review on Latest Anti Aging Studies 3 31 23- TruDiagnostic
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Hyperbaric Oxygen Therapy with HBOT expert, Dr. Jason Sonners | TruDiagnostics Q&A Series 2023
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Hyperbaric Oxygen Therapy with HBOT expert, Dr. Jason Sonners | TruDiagnostics Q&A Series 2023
Quicksilver Scientific's Founder & CEO, Dr. Chris Shade, joins Hannah Went to discuss collaboration
Переглядів 888Рік тому
Quicksilver Scientific's Founder & CEO, Dr. Chris Shade, joins Hannah Went to discuss collaboration
What exactly is Plasma Exchange? | An Interview with one of the pioneers, Dr. Dobri Kiprov
Переглядів 507Рік тому
What exactly is Plasma Exchange? | An Interview with one of the pioneers, Dr. Dobri Kiprov
Treating Mental Illnesses with Ketamine to Slow Down Accelerated Biological Aging
Переглядів 169Рік тому
Treating Mental Illnesses with Ketamine to Slow Down Accelerated Biological Aging
Nutritional Excellence and Longevity discussed | Q&A with Dr. Fuhrman
Переглядів 354Рік тому
Nutritional Excellence and Longevity discussed | Q&A with Dr. Fuhrman
Effects of tobacco, alcohol, and marijuana on DNA methylation | Q&A with Natalia Carreras
Переглядів 368Рік тому
Effects of tobacco, alcohol, and marijuana on DNA methylation | Q&A with Natalia Carreras
Dr. Vincent Giampapa Interview | Q&A Series with Hannah Went | TruDiagnostic 2022
Переглядів 583Рік тому
Dr. Vincent Giampapa Interview | Q&A Series with Hannah Went | TruDiagnostic 2022
Hannah Went with Dr. Katherine Zagone, CMO and Co-Founder of Clockwize | Q&A TruDiagnostic 2022
Переглядів 115Рік тому
Hannah Went with Dr. Katherine Zagone, CMO and Co-Founder of Clockwize | Q&A TruDiagnostic 2022
Lucas Aoun Podcast with guest Ryan Smith
Переглядів 1522 роки тому
Lucas Aoun Podcast with guest Ryan Smith
Interview with Ryan Smith and Dr Mercola: The impact of epigenetic age tracking
Переглядів 7702 роки тому
Interview with Ryan Smith and Dr Mercola: The impact of epigenetic age tracking
Epigenetic Methylation & Age: A Recap of Developments in 2021
Переглядів 1,2 тис.2 роки тому
Epigenetic Methylation & Age: A Recap of Developments in 2021
Deconstructing The Epigenetic Methylation ClocK
Переглядів 8872 роки тому
Deconstructing The Epigenetic Methylation ClocK
How to use TruDiagnostic's blood spot collection kit
Переглядів 4,9 тис.2 роки тому
How to use TruDiagnostic's blood spot collection kit
Researchers Identified the Role of KDM4B Gene in Skeletal Aging
Переглядів 903 роки тому
Researchers Identified the Role of KDM4B Gene in Skeletal Aging
I think people can get useful information out of this kind of tests, as long you don't look at it like a sort of oracle, but more like a compass (eg. Am I going in the right direction or do I need to correct my course?). But some criticism is valid, this kind of tests have high correlation with lifespan, but have yet to stand the test of time.
Kind of disappointed that Peter Attia is so misinformed and so behind on the latest technologies in the field he is considered an authority in. Loved his book Outlive and hope he can avoid confusing people in future interviews. I found my TruAge report to be insightful and useful, look forward to monitoring changes with regular testing.
Smoke and mirrors. A true lab director would never refer to the instruments as machines. I'm sure he's qualified scenically, just highly inexperienced.
The narrator is a genius and gives a lot of confidence in the company. I just bought the test
I question the accuracy of these measurements, having recently done an OMIC test ( my fourth). My A1C showed 6.4, fasting Blood Sugar 112. I did a real blood test the same week. My A1C, 5.3. ( my highest in years, it’s normally 5.0 ). My fasting BS was 79. It’s never been above 85.
Where can I get the cheat sheet?
ECGC? I think he must mean EGCG. It would be great to know about more supplements, vitamins and minerals. Chocolate polyphenols, olive polyphenols, ergothioneine, hibiscus, artichoke, aronia, lion's mane mushroom, cranberry, pterostilbene, saffron, spermidine, ursolic acid, and pregnenolone. And I really would like results from toxins found in the blood: lead, fluoride, cadmium, iron (at higher than recommended), mercury, arsenic, acrylamide, advanced glycation end-products, polybrominated diphenyl ethers, and organophosphate.
I just received my first SymphonyAge report today. I noted that my "heart age" was 58, higher than my chronological age of 56.66 (while lung age was 50, though they are supposed to be highly correlated). Your video above made it sound like factors such as heart rate, blood pressure, BMI, and weight circumference would be figured in. However, these were not requested/required of the participant, so how can they be part of the calculation? As an endurance runner, my non-blood biomarkers are excellent. So, why is my heart score above my calendar age? And what does seeing a score of 58 do for me when I already run daily and eat a whole-food diet? It doesn't say what can be done to improve it (other than things I already do).
Exciting release team! Will have to check my old tests and do a new one with this!
Congratulations to Ryan and all the Tru Diagnostic team!!! We need tools to better understand our patients, specially in the prevention amd early diagnosis area. And I guess SymphonyAge will help us a lot including to show and convince the patient for a specific treatment or conduct!!!!
Thank you!!
is mild hbot good for sleep? what brands do you recommend for home purchase
Would be good to study the effects of plasma donation which removes a significant but lower quantity of plasma on each round. ~25% for donation vs ~60% for TPE. Donation, which can be done monthly, is free at local blood banks in US. vs TPE which physicians in the "longevity" world are charging thousands for. Need dose response (minimum effective volume and frequency) as well as more data on gene expression and tissue changes. May be that it would take many months to see significant tissues changes. As an older person I will try to use some of the blood parameters in the 2022 Conboy paper to assess my plasma donation regime.
"...disrupt red cells for DNA extraction..."? Credibility undermined in first 30 secs.
They will result this as a FASTING blood glucose result - be aware and be fasted for accurate results! It was not clear to me they would be testing fasting glucose when I prepared and sent the sample
❤🙏🏻🎯🚀
Let him talk. That would have been your job.
Thanks for the feedback, Susan!
Reduced pressure results in an increase in red blood cells, however no mention of what happens to red blood cells due to longer / sustained HBOT. I would be cautious.
Please don't call a linear regression model "AI"
Here's a link to the slide deck from the talk: docs.google.com/presentation/d/1vJn3E5WVnjNhOANNxuj9mNHMF-YxmYTYPd0lyc3dr1U/edit?usp=sharing
Where’s part 1?
Great video
My Omic HBA1C came in at 6.5. I get it blood tested twice a year and have never been over 5.3, the average is about 5.0. So the Omic correlation isn’t accurate
I had the same result. Two A1Cs a year apart both 5.5 (last one done in Feb '24). Theirs showed 6.36.
My Omic HbA1c came in at 6.5, and it's 5.6 on my latest Quest lab.
It is possible that Hemoglobin A1C is just causing more damage in your body, equivalent to what 6.5 would be doing in an average person. If that is the case, maybe figure out how to mitigate that. Perhaps some supplements to fight glycation. I take benfotiamine and curcumin for that. I haven't been tested yet, so this is entirely speculation. I am actually very curious where it would put mine. I made and am using a Low Advanced Glycation End-products diet, combined with several supplements, to reduce the creation of AGEs in my body. It is not an easy diet, and almost impossible to eat out and stay compliant.
This is wonderful. Really useful and well explained
Isoputreanine is in chickens, so is it also in eggs?
ribitol increases succinate!!
Is Hsp70 in Kejun Ying's adaptage?
you call a Hazard Ratio of 1.02..1.08 incredible? (~@3.00) In which direction? incredible good or incredible insignificant? @7:35 you call principal component algorithms "incredibly precise"... Well, that's b.s.. First, PCA in itself is a stupid algorithm, 2nd class at best and second, you can not call an algorithm "incredibly precise". stopped watching.
Hazard ratio per year. An 8% chance of dying in a year sounds pretty dreadful to me. For most things, scientists add the hazard ratios for several years together. Often 5 years. If you want extreme, something extreme must have happened, like breaking a hip, or having a major heart attack.
Fantastic. Really exciting and ground breaking.
Great content. ....🌻🌈💝
This is absolutely INCREDIBLE~~~ Thank you both for partnering up. I am a believer in Dr Shade and in TruDiagnostic!!
This was an amazing presentation Ryan! Holy cow, you guys have been doing great work over the last 5 years. Will be very excited to offer this newer generation testing to our patients. This webinar answered a lot of longstanding questions I had about DNA methylation proxies.
Would like to see a comparison with GrimAge
46:19 is there any reason you don't offer a GrimAge report? You can calculate that with just methylation data, correct?
Love it🔥
Great information🔥
So when is this available commerecially?
My hemoglobin A1C DNAmage is totally not correlated with my actual hemoglobin A1c but I still worry b/c despite having better baseline glucose,I have thicker spikes than most epople, and some kinds of fruit may not be safe for me to eat
Can she biobank my samples? I'm in Boston
PS. There was mention of replacing old plasma with young plasma but this has many drawbacks, Instead it t would be interesting to test simple plasma donation (in older people) as is done at blood banks in the US. Each donation takes out about 25% of plasma and can be done monthly. This isn't as much as the Conboy work on NBE which took out 50% in animals, but it is a significant volume. It's also an easy thing to do unlike the multi-thousand dollar clones of the Conboy process which are being done now and in the pipeline by new startups.
I looked into this. American Red Cross can do plasma donation (i.e. exchange for our purpose!), but only if your blood type is of 2 specific types, which mine is not. There are several clinics in Mexico that offer plasma exchange procedures FYI...
In plasma donation, they just replace it with saline water. Problem is, you lose a lot of albumen. The liver should replace this, but until it does, you will have a low level. Albumen is a powerful antioxidant, and has many important roles. In a procedure called plasmaphereses, they basically do the same extraction, but they put albumen back as well as saline water. The downside is that you pay, and need a doctor's prescription. Donation, on the other hand, they give you money.
@@manojpadki There are at least two big companies that will take your plasma (donation) and pay you. They don't care about blood type. They process the stuff and turn it into drugs, separating and concentrating components. These are lifesaving drugs for some people.
Thanks. On NMN and AKG, I recall a presentation, 2022 I believe, by Adam Antebi in which he showed that low insulin resulted in increased NMN and AKG. How low in humans I have no idea as I think work was done in mice or rats. But low insulin has multiple benefits and it would be interesting to correlate it with rate of epi aging. Also work by Janet Lord which showed that long time exercisers maintained their thymus and immunity well into 70s and 80s. Along with that work from Riekelt Houtkooper's lab which showed that NAD+ was preserved in older people who met certain exercise thresholds. Seems like diet and exercise (assuming no smoking and drinking) may negate the need to involve some of the interventions, like Fahey's work on the thymus, or taking NR and NMN. Would just need some work to sort out, but maybe something as simple as determining if rate of aging is slowed to maximum amount by diet and exercise regimes alone. It appeared that modest CR by itself when a long way to doing this.
Any idea when trial results will publish?
1:00 DNA extraction from red blood cells is not scientifically accurate - since there is no DNA (no nucleus) inside RBC (en.wikipedia.org/wiki/Red_blood_cell)
My epitoc2 is 592
This is fantastic, thank you.
Is it possible or can be possible in near future to increase height at any age or after growthplates fusion. Can person of 5’ become 6’ or , 6’ person become 7’ . Is it possible? I want research should be done in this area . No cut or operation just some machine n biological team who will supervise everything and plans diet n schedule . Something like that.
Is it safe to undergo HBOT for a person who has had a Stapedectomy (middle ear surgery)? Will the 2X Oxygen pressure damage the inserted prosthesis?
Many of my patients are on testosterone replacement after menopause or oophorectomy, and that is not mentioned instead of DHEA. DHEA is only useful in men and is a precursor to Testosterone. After menopause women are healthier if they are treated with E2 and T. Has Testosterone been considered?
Are you looking for a test subject ? Sign me up!
Do the plasma bags touch a lot of plastic?
Excited for the results of his study.